Dctn4 (dynactin subunit 4) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Dctn4 (dynactin subunit 4) Heterocephalus glaber
Analyze
Symbol: Dctn4
Name: dynactin subunit 4
RGD ID: 18925675
Description: PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH cystic fibrosis (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasmic dynein complex (ortholog); focal adhesion (ortholog); kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,951,228 - 9,986,164 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,951,520 - 9,986,194 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dctn4Naked Mole-Ratfamilial adenomatous polyposis 1  ISODCTN4 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial adenomatous polyposis 1ClinVarPMID:17963004 more ...
Dctn4Naked Mole-RatHereditary Neoplastic Syndromes  ISODCTN4 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:17963004 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dctn4Naked Mole-Ratcystic fibrosis  ISODCTN4 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22772370
Dctn4Naked Mole-RatPseudomonas Infections  ISODCTN4 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22772370


Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dctn4Naked Mole-Ratcell cortex located_inIEAUniProtKB-SubCell:SL-0138150520179 UniProtGO_REF:0000044
Dctn4Naked Mole-Ratcentrosome located_inIEAUniProtKB:Q9UJW0 and ensembl:ENSP00000416968150520179 EnsemblGO_REF:0000107
Dctn4Naked Mole-Ratcentrosome located_inIEAUniProtKB-SubCell:SL-0048150520179 UniProtGO_REF:0000044
Dctn4Naked Mole-Ratcytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
Dctn4Naked Mole-Ratcytoplasmic dynein complex part_ofISODctn4 (Rattus norvegicus)9068941PMID:10525537MGIPMID:10525537 and REF_RGD_ID:632517
Dctn4Naked Mole-Ratcytoskeleton located_inIEAUniProtKB-KW:KW-0206150520179 UniProtGO_REF:0000043
Dctn4Naked Mole-Ratdynactin complex part_ofIEAPANTHER:PTN000315427 and PANTHER:PTN000315430150520179 TreeGrafterGO_REF:0000118
Dctn4Naked Mole-Ratdynactin complex part_ofIEAInterPro:IPR008603150520179 InterProGO_REF:0000002
Dctn4Naked Mole-Ratfocal adhesion located_inISODctn4 (Rattus norvegicus)9068941 RGDPMID:10607597 and REF_RGD_ID:70710
Dctn4Naked Mole-Ratkinetochore  ISODctn4 (Rattus norvegicus)9068941 RGDPMID:10607597 and REF_RGD_ID:70710
Dctn4Naked Mole-Ratsarcomere located_inIEAUniProtKB-SubCell:SL-0313150520179 UniProtGO_REF:0000044
Dctn4Naked Mole-Ratspindle pole  ISODctn4 (Rattus norvegicus)9068941 RGDPMID:10607597 and REF_RGD_ID:70710
Dctn4Naked Mole-Ratstress fiber located_inIEAUniProtKB-SubCell:SL-0501150520179 UniProtGO_REF:0000044
1 to 13 of 13 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dctn4Naked Mole-Ratmitochondria transport pathway  ISODCTN4 (Homo sapiens)9068941 RGDPMID:15473859 and REF_RGD_ID:10402155
PMID:21993625   PMID:22301074   PMID:30032202  



Dctn4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,951,228 - 9,986,164 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,951,520 - 9,986,194 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DCTN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,708,440 - 150,759,017 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5150,706,840 - 150,759,095 (-)EnsemblGRCh38hg38GRCh38
GRCh375150,088,002 - 150,138,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365150,068,502 - 150,118,769 (-)NCBINCBI36Build 36hg18NCBI36
Build 345150,068,502 - 150,118,769NCBI
Celera5146,169,659 - 146,220,011 (-)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5145,234,095 - 145,284,314 (-)NCBIHuRef
CHM1_15149,521,113 - 149,571,477 (-)NCBICHM1_1
T2T-CHM13v2.05151,244,948 - 151,295,528 (-)NCBIT2T-CHM13v2.0
Dctn4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391860,659,226 - 60,691,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1860,659,257 - 60,691,838 (+)EnsemblGRCm39 Ensembl
GRCm381860,526,154 - 60,558,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1860,526,185 - 60,558,766 (+)EnsemblGRCm38mm10GRCm38
MGSCv371860,685,875 - 60,718,416 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361860,651,590 - 60,684,131 (+)NCBIMGSCv36mm8
Celera1861,811,724 - 61,843,194 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1834.36NCBI
Dctn4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81856,251,187 - 56,279,844 (+)NCBIGRCr8
mRatBN7.21853,982,355 - 54,009,409 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1853,982,358 - 54,009,399 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1856,070,601 - 56,095,730 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01856,785,203 - 56,810,332 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01854,606,356 - 54,630,946 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01855,797,188 - 55,824,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1855,797,198 - 55,822,036 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,030,617 - 55,057,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,478,185 - 56,502,775 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11856,550,362 - 56,576,103 (+)NCBI
Celera1852,136,101 - 52,160,691 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Dctn4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554153,850,086 - 3,886,953 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554153,850,475 - 3,886,953 (+)NCBIChiLan1.0ChiLan1.0
DCTN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24145,938,960 - 145,992,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15144,078,506 - 144,128,568 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05146,134,587 - 146,184,639 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15152,138,052 - 152,187,140 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5152,138,052 - 152,187,140 (-)Ensemblpanpan1.1panPan2
DCTN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,423,591 - 58,453,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,423,635 - 58,450,874 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,188,803 - 58,218,047 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0458,903,399 - 58,932,644 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl458,903,411 - 58,932,644 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1458,691,730 - 58,720,975 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0458,806,123 - 58,835,620 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,337,230 - 59,366,747 (+)NCBIUU_Cfam_GSD_1.0
Dctn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213142,678,462 - 142,711,176 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365044,252,431 - 4,285,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365044,252,442 - 4,285,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCTN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,681,003 - 151,783,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,681,001 - 151,713,923 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DCTN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,321,724 - 53,364,507 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603424,355,939 - 24,401,037 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000009231   ⟹   ENSHGLP00000009132
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247749,951,228 - 9,986,164 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000009232   ⟹   ENSHGLP00000009133
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247749,951,228 - 9,986,164 (-)Ensembl
RefSeq Acc Id: XM_004854433   ⟹   XP_004854490
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247749,951,520 - 9,986,194 (-)NCBI
RefSeq Acc Id: XM_004854434   ⟹   XP_004854491
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247749,951,520 - 9,986,194 (-)NCBI
RefSeq Acc Id: XM_021266231   ⟹   XP_021121890
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247749,951,520 - 9,985,756 (-)NCBI
Protein RefSeqs XP_004854490 (Get FASTA)   NCBI Sequence Viewer  
  XP_004854491 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121890 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB05082 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009132
  ENSHGLP00000009133
GenBank Protein JAO03211 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004854491   ⟸   XM_004854434
- Peptide Label: isoform X3
- UniProtKB: A0A0P6K8P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004854490   ⟸   XM_004854433
- Peptide Label: isoform X1
- UniProtKB: G5B721 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121890   ⟸   XM_021266231
- Peptide Label: isoform X2
- UniProtKB: A0AAX6TJ63 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000009132   ⟸   ENSHGLT00000009231
Ensembl Acc Id: ENSHGLP00000009133   ⟸   ENSHGLT00000009232



1 to 12 of 12 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000006565 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000009231 ENTREZGENE
  ENSHGLT00000009232 ENTREZGENE
InterPro DCTN4 UniProtKB/TrEMBL
KEGG Report hgl:101697514 UniProtKB/TrEMBL
NCBI Gene Dctn4 ENTREZGENE
PANTHER DYNACTIN SUBUNIT 4 UniProtKB/TrEMBL
  PTHR13034 UniProtKB/TrEMBL
Pfam Dynactin_p62 UniProtKB/TrEMBL
UniProt A0A0P6K8P7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TJ63 ENTREZGENE, UniProtKB/TrEMBL
  G5B721 ENTREZGENE, UniProtKB/TrEMBL
1 to 12 of 12 rows