Hook3 (hook microtubule tethering protein 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Hook3 (hook microtubule tethering protein 3) Heterocephalus glaber
Analyze
Symbol: Hook3
Name: hook microtubule tethering protein 3
RGD ID: 18923597
Description: ENCODES a protein that exhibits dynactin binding (ortholog); dynein intermediate chain binding (ortholog); dynein light chain binding (ortholog); INVOLVED IN early endosome to late endosome transport (ortholog); endosome organization (ortholog); endosome to lysosome transport (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A12 (ortholog); Dwarfism (ortholog); Idiopathic Basal Ganglia Calcification 1 (ortholog); FOUND IN centriolar satellite (ortholog); cis-Golgi network (ortholog); FHF complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hook homolog 3; Hook-like protein 3; protein Hook homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624780127,090 - 235,648 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624780127,718 - 237,701 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hook3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624780127,090 - 235,648 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624780127,718 - 237,701 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HOOK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38842,896,978 - 43,030,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl842,896,946 - 43,030,535 (+)EnsemblGRCh38hg38GRCh38
GRCh37842,752,121 - 42,885,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36842,871,190 - 42,994,084 (+)NCBINCBI36Build 36hg18NCBI36
Build 34842,871,189 - 42,994,084NCBI
Celera841,700,858 - 41,834,504 (+)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef841,275,201 - 41,408,559 (+)NCBIHuRef
CHM1_1842,798,954 - 42,932,603 (+)NCBICHM1_1
T2T-CHM13v2.0843,165,918 - 43,299,475 (+)NCBIT2T-CHM13v2.0
Hook3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,511,449 - 26,609,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl826,511,449 - 26,609,252 (-)EnsemblGRCm39 Ensembl
GRCm38826,021,421 - 26,119,618 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl826,021,421 - 26,119,224 (-)EnsemblGRCm38mm10GRCm38
MGSCv37827,131,893 - 27,229,696 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36827,497,435 - 27,584,559 (-)NCBIMGSCv36mm8
Celera827,491,977 - 27,589,321 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.29NCBI
Hook3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81672,656,929 - 72,751,696 (+)NCBIGRCr8
mRatBN7.21665,954,293 - 66,058,812 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1665,954,350 - 66,061,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1671,237,359 - 71,327,657 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01674,643,695 - 74,733,986 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01669,883,875 - 69,974,033 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01670,710,347 - 70,818,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01670,376,538 - 70,483,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,338,144 - 70,424,173 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1663,865,670 - 63,960,092 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Hook3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545713,149,013 - 13,249,321 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545713,149,013 - 13,249,524 (+)NCBIChiLan1.0ChiLan1.0
HOOK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2761,354,487 - 61,487,797 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1837,070,523 - 37,203,836 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0842,145,427 - 42,278,727 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1839,589,942 - 39,720,341 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl839,595,762 - 39,711,043 (+)Ensemblpanpan1.1panPan2
HOOK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11622,791,198 - 22,940,168 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1622,784,267 - 22,901,991 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1623,296,402 - 23,406,210 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01624,542,973 - 24,652,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1624,491,022 - 24,652,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11622,911,279 - 23,020,972 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01623,476,174 - 23,585,989 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01623,527,294 - 23,636,812 (-)NCBIUU_Cfam_GSD_1.0
Hook3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494345,815,977 - 45,936,880 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493710860 - 110,939 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004937108873 - 110,949 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOOK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1711,818,031 - 11,923,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11711,817,963 - 11,919,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HOOK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1840,897,108 - 41,023,068 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl840,897,209 - 41,021,808 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666052746,378 - 872,950 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000004321   ⟹   ENSHGLP00000004261
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624780127,090 - 235,648 (+)Ensembl
RefSeq Acc Id: XM_004855259   ⟹   XP_004855316
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624780127,718 - 237,701 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855316 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13065 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004261
GenBank Protein JAN97062 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004855316   ⟸   XM_004855259
- UniProtKB: G5BUV4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004261   ⟸   ENSHGLT00000004321


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003116 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004321 ENTREZGENE
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Hook_C UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
KEGG Report hgl:101704484 UniProtKB/TrEMBL
NCBI Gene Hook3 ENTREZGENE
PANTHER HOOK PROTEINS UniProtKB/TrEMBL
  PROTEIN HOOK HOMOLOG 3 UniProtKB/TrEMBL
Pfam HOOK UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
Superfamily-SCOP Hook domain UniProtKB/TrEMBL
UniProt G5BUV4 ENTREZGENE, UniProtKB/TrEMBL