HOOK3 (hook microtubule tethering protein 3) - Rat Genome Database
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Gene: HOOK3 (hook microtubule tethering protein 3) Sus scrofa
Analyze
Symbol: HOOK3
Name: hook microtubule tethering protein 3
RGD ID: 14081346
Description: ENCODES a protein that exhibits dynactin binding (inferred); dynein intermediate chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN interkinetic nuclear migration (ortholog); microtubule anchoring at centrosome (ortholog); negative regulation of neurogenesis (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A12 (ortholog); Dwarfism (ortholog); Idiopathic Basal Ganglia Calcification 1 (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: protein Hook homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1711,817,987 - 11,924,884 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11711,817,963 - 11,919,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
HOOK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1711,817,987 - 11,924,884 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11711,817,963 - 11,919,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HOOK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl842,896,946 - 43,030,535 (+)EnsemblGRCh38hg38GRCh38
GRCh38842,896,978 - 43,030,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37842,752,121 - 42,885,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36842,871,190 - 42,994,084 (+)NCBINCBI36hg18NCBI36
Build 34842,871,189 - 42,994,084NCBI
Celera841,700,858 - 41,834,504 (+)NCBI
Cytogenetic Map8p11.21NCBI
HuRef841,275,201 - 41,408,559 (+)NCBIHuRef
CHM1_1842,798,954 - 42,932,603 (+)NCBICHM1_1
Hook3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,511,449 - 26,609,646 (-)NCBIGRCm39mm39
GRCm39 Ensembl826,511,449 - 26,609,252 (-)Ensembl
GRCm38826,021,421 - 26,119,618 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl826,021,421 - 26,119,224 (-)EnsemblGRCm38mm10GRCm38
MGSCv37827,131,893 - 27,229,696 (-)NCBIGRCm37mm9NCBIm37
MGSCv36827,497,435 - 27,584,559 (-)NCBImm8
Celera827,491,977 - 27,589,321 (-)NCBICelera
Cytogenetic Map8A2NCBI
Hook3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21665,954,293 - 66,058,812 (+)NCBI
Rnor_6.01670,710,347 - 70,818,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01670,376,538 - 70,483,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,338,144 - 70,424,173 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1663,865,670 - 63,960,092 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Hook3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545713,149,013 - 13,249,321 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545713,149,013 - 13,249,524 (+)NCBIChiLan1.0ChiLan1.0
HOOK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1839,589,942 - 39,720,341 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl839,595,762 - 39,711,043 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0842,145,427 - 42,278,727 (+)NCBIMhudiblu_PPA_v0panPan3
HOOK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1622,784,267 - 22,901,991 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11622,791,198 - 22,940,168 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Hook3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004937108873 - 110,949 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOOK3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1840,897,108 - 41,023,068 (+)NCBI
ChlSab1.1 Ensembl840,897,209 - 41,021,808 (+)Ensembl
Hook3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624780127,718 - 237,701 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000031247   ⟹   ENSSSCP00000019399
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,818,028 - 11,911,920 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042749   ⟹   ENSSSCP00000047583
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,817,987 - 11,924,884 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000046572   ⟹   ENSSSCP00000032150
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,818,063 - 11,911,895 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062728   ⟹   ENSSSCP00000057032
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,818,039 - 11,911,920 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000074154   ⟹   ENSSSCP00000069333
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,818,063 - 11,911,895 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000078456   ⟹   ENSSSCP00000071960
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,822,895 - 11,909,869 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000079974   ⟹   ENSSSCP00000068544
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1711,818,063 - 11,913,439 (+)Ensembl
RefSeq Acc Id: XM_021077846   ⟹   XP_020933505
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11711,817,996 - 11,919,152 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077847   ⟹   XP_020933506
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11711,817,963 - 11,911,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077848   ⟹   XP_020933507
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11711,844,378 - 11,919,152 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077849   ⟹   XP_020933508
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11711,847,847 - 11,919,152 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077850   ⟹   XP_020933509
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11711,847,899 - 11,919,152 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020933506   ⟸   XM_021077847
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020933505   ⟸   XM_021077846
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020933507   ⟸   XM_021077848
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020933508   ⟸   XM_021077849
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020933509   ⟸   XM_021077850
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSSSCP00000071960   ⟸   ENSSSCT00000078456
RefSeq Acc Id: ENSSSCP00000069333   ⟸   ENSSSCT00000074154
RefSeq Acc Id: ENSSSCP00000068544   ⟸   ENSSSCT00000079974
RefSeq Acc Id: ENSSSCP00000019399   ⟸   ENSSSCT00000031247
RefSeq Acc Id: ENSSSCP00000047583   ⟸   ENSSSCT00000042749
RefSeq Acc Id: ENSSSCP00000032150   ⟸   ENSSSCT00000046572
RefSeq Acc Id: ENSSSCP00000057032   ⟸   ENSSSCT00000062728
Protein Domains
Calponin-homology (CH)   HOOK   HOOK_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024486 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000019399 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000032150 UniProtKB/TrEMBL
  ENSSSCP00000047583 UniProtKB/TrEMBL
  ENSSSCP00000057032 UniProtKB/TrEMBL
  ENSSSCP00000068544 UniProtKB/TrEMBL
  ENSSSCP00000069333 UniProtKB/TrEMBL
  ENSSSCP00000071960 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031247 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000042749 UniProtKB/TrEMBL
  ENSSSCT00000046572 UniProtKB/TrEMBL
  ENSSSCT00000062728 UniProtKB/TrEMBL
  ENSSSCT00000074154 UniProtKB/TrEMBL
  ENSSSCT00000078456 UniProtKB/TrEMBL
  ENSSSCT00000079974 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Hook-like_fam UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
NCBI Gene HOOK3 ENTREZGENE
Pfam HOOK UniProtKB/TrEMBL
  HOOK_N UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
UniProt A0A286ZL02_PIG UniProtKB/TrEMBL
  A0A287AUQ4_PIG UniProtKB/TrEMBL
  A0A287BKK1_PIG UniProtKB/TrEMBL
  A0A5G2QYW3_PIG UniProtKB/TrEMBL
  A0A5G2R6J5_PIG UniProtKB/TrEMBL
  A0A5G2RCY4_PIG UniProtKB/TrEMBL
  I3L5U9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:98037 ENTREZGENE