Eya1 (EYA transcriptional coactivator and phosphatase 1) - Rat Genome Database

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Gene: Eya1 (EYA transcriptional coactivator and phosphatase 1) Heterocephalus glaber
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Symbol: Eya1
Name: EYA transcriptional coactivator and phosphatase 1
RGD ID: 18921529
Description: ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); aorta morphogenesis (ortholog); branching involved in ureteric bud morphogenesis (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH anterior segment dysgenesis (ortholog); branchiooculofacial syndrome (ortholog); branchiootic syndrome (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: eyes absent homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474419,782,790 - 19,977,335 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474419,782,174 - 19,975,496 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Eya1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474419,782,790 - 19,977,335 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474419,782,174 - 19,975,496 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EYA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38871,197,433 - 71,548,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl871,197,433 - 71,592,025 (-)EnsemblGRCh38hg38GRCh38
GRCh37872,109,668 - 72,460,329 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36872,272,222 - 72,437,021 (-)NCBINCBI36Build 36hg18NCBI36
Build 34872,272,221 - 72,437,021NCBI
Celera868,106,627 - 68,271,433 (-)NCBICelera
Cytogenetic Map8q13.3NCBI
HuRef867,603,371 - 67,768,504 (-)NCBIHuRef
CHM1_1872,164,260 - 72,329,031 (-)NCBICHM1_1
T2T-CHM13v2.0871,626,530 - 71,983,583 (-)NCBIT2T-CHM13v2.0
Eya1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,239,177 - 14,381,259 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,239,178 - 14,380,459 (-)EnsemblGRCm39 Ensembl
GRCm38114,168,953 - 14,311,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,168,954 - 14,310,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,159,039 - 14,300,280 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36114,154,172 - 14,295,413 (-)NCBIMGSCv36mm8
Celera114,109,695 - 14,251,151 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.31NCBI
Eya1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr859,646,599 - 9,884,609 (+)NCBIGRCr8
mRatBN7.254,863,501 - 5,101,483 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl54,955,543 - 5,101,483 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.054,275,728 - 4,495,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl54,373,626 - 4,513,142 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.054,252,745 - 4,487,853 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.454,132,825 - 4,276,837 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera54,454,356 - 4,554,997 (+)NCBICelera
Celera54,581,829 - 4,692,568 (+)NCBICelera
Cytogenetic Map5q11NCBI
Eya1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554448,495,530 - 8,655,100 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554448,336,071 - 8,655,041 (+)NCBIChiLan1.0ChiLan1.0
EYA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2786,938,623 - 87,280,457 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1862,568,011 - 62,730,070 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0867,728,057 - 68,060,069 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1869,387,769 - 69,551,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl869,387,769 - 69,551,829 (-)Ensemblpanpan1.1panPan2
EYA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12920,176,306 - 20,595,131 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2920,177,014 - 20,525,653 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2920,436,698 - 20,855,121 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02920,275,380 - 20,693,971 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2920,274,650 - 20,771,147 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12920,325,900 - 20,743,158 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02920,378,421 - 20,796,035 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02920,660,077 - 21,078,705 (-)NCBIUU_Cfam_GSD_1.0
Eya1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530358,739,647 - 59,053,061 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936648395,524 - 546,729 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936648395,526 - 546,705 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EYA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl463,970,807 - 64,328,105 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1463,970,939 - 64,328,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2469,915,648 - 69,943,761 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EYA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1866,902,961 - 67,238,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl866,902,972 - 67,060,567 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603974,161,305 - 74,511,047 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004842059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002393928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01023499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000027444   ⟹   ENSHGLP00000027203
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474419,782,790 - 19,975,386 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000027445   ⟹   ENSHGLP00000027204
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474419,787,419 - 19,977,335 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000027446   ⟹   ENSHGLP00000027205
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474419,787,419 - 19,977,335 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000027447   ⟹   ENSHGLP00000027206
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474419,787,866 - 19,975,246 (+)Ensembl
RefSeq Acc Id: XM_004842059   ⟹   XP_004842116
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,176 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_013071264   ⟹   XP_012926718
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,177 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_021256021   ⟹   XP_021111680
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,177 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_021256022   ⟹   XP_021111681
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,176 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_021256023   ⟹   XP_021111682
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,176 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_021256024   ⟹   XP_021111683
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,175 - 19,975,496 (+)NCBI
RefSeq Acc Id: XM_021256025   ⟹   XP_021111684
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,174 - 19,960,970 (+)NCBI
RefSeq Acc Id: XM_021256026   ⟹   XP_021111685
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,832,482 - 19,975,496 (+)NCBI
RefSeq Acc Id: XR_002393928
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474419,782,175 - 19,975,255 (+)NCBI
RefSeq Acc Id: XP_021111684   ⟸   XM_021256025
- Peptide Label: isoform X7
RefSeq Acc Id: XP_021111683   ⟸   XM_021256024
- Peptide Label: isoform X6
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842116   ⟸   XM_004842059
- Peptide Label: isoform X5
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111681   ⟸   XM_021256022
- Peptide Label: isoform X3
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111682   ⟸   XM_021256023
- Peptide Label: isoform X4
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111680   ⟸   XM_021256021
- Peptide Label: isoform X1
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926718   ⟸   XM_013071264
- Peptide Label: isoform X2
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111685   ⟸   XM_021256026
- Peptide Label: isoform X8
- UniProtKB: G5B8F9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027205   ⟸   ENSHGLT00000027446
Ensembl Acc Id: ENSHGLP00000027203   ⟸   ENSHGLT00000027444
Ensembl Acc Id: ENSHGLP00000027206   ⟸   ENSHGLT00000027447
Ensembl Acc Id: ENSHGLP00000027204   ⟸   ENSHGLT00000027445


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019347 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027444 ENTREZGENE
  ENSHGLT00000027446 ENTREZGENE
  ENSHGLT00000027447 ENTREZGENE
Gene3D-CATH 3.40.50.12350 UniProtKB/TrEMBL
InterPro EYA_dom UniProtKB/TrEMBL
  EYA_dom_metazoan UniProtKB/TrEMBL
  EYA_dom_sf UniProtKB/TrEMBL
  EYA_fam UniProtKB/TrEMBL
NCBI Gene Eya1 ENTREZGENE
PANTHER EYES ABSENT UniProtKB/TrEMBL
  EYES ABSENT HOMOLOG 1 UniProtKB/TrEMBL
Pfam Hydrolase UniProtKB/TrEMBL
UniProt G5B8F9 ENTREZGENE, UniProtKB/TrEMBL