Eya1 (EYA transcriptional coactivator and phosphatase 1) - Rat Genome Database

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Gene: Eya1 (EYA transcriptional coactivator and phosphatase 1) Mus musculus
Analyze
Symbol: Eya1
Name: EYA transcriptional coactivator and phosphatase 1
RGD ID: 1317055
MGI Page MGI
Description: Exhibits RNA binding activity and protein tyrosine phosphatase activity. Involved in several processes, including animal organ development; cell fate specification; and positive regulation of cell population proliferation. Localizes to cytoplasm; nucleus; and protein-DNA complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study branchiootorenal syndrome. Human ortholog(s) of this gene implicated in branchiootorenal syndrome and branchiootorenal syndrome 1. Orthologous to human EYA1 (EYA transcriptional coactivator and phosphatase 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol; 4-hydroperoxycyclophosphamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b; bor; eyes absent 1 homolog; eyes absent homolog 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,239,177 - 14,381,259 (-)NCBIGRCm39mm39
GRCm39 Ensembl114,239,178 - 14,380,459 (-)Ensembl
GRCm38114,168,953 - 14,311,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,168,954 - 14,310,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,159,039 - 14,300,280 (-)NCBIGRCm37mm9NCBIm37
MGSCv36114,154,172 - 14,295,413 (-)NCBImm8
Celera114,109,695 - 14,251,151 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure development  (IBA,IGI)
animal organ morphogenesis  (IMP)
aorta morphogenesis  (IMP)
branching involved in ureteric bud morphogenesis  (IGI)
cell differentiation  (IBA)
cell fate commitment  (IMP)
cellular protein localization  (IMP)
cellular response to DNA damage stimulus  (IEA)
chromatin organization  (IEA)
cochlea morphogenesis  (IMP)
DNA repair  (IEA)
double-strand break repair  (ISO)
ear morphogenesis  (IEA)
embryonic skeletal system morphogenesis  (IMP)
establishment of mitotic spindle orientation  (IGI,IMP)
establishment or maintenance of apical/basal cell polarity  (IMP)
histone dephosphorylation  (IBA,ISO)
inner ear morphogenesis  (IGI,IMP)
lung epithelial cell differentiation  (IGI)
mesodermal cell fate specification  (IDA)
metanephros development  (IMP)
middle ear morphogenesis  (IMP)
multicellular organism development  (IEA)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IBA,IMP)
neuron fate specification  (IGI)
otic vesicle development  (IGI)
otic vesicle morphogenesis  (IMP)
outer ear morphogenesis  (IMP)
outflow tract morphogenesis  (IMP)
pattern specification process  (IGI,IMP)
peptidyl-tyrosine dephosphorylation  (IEA)
pharyngeal system development  (IMP)
positive regulation of DNA repair  (IBA,ISO)
positive regulation of epithelial cell proliferation  (IMP)
positive regulation of Notch signaling pathway  (IMP)
positive regulation of secondary heart field cardioblast proliferation  (IGI)
positive regulation of transcription by RNA polymerase II  (IGI)
positive regulation of transcription, DNA-templated  (IDA)
protein dephosphorylation  (IDA)
protein sumoylation  (IDA)
regulation of neuron differentiation  (IGI,IMP)
response to ionizing radiation  (ISO)
semicircular canal morphogenesis  (IMP)
striated muscle tissue development  (IGI)
ureteric bud development  (IGI)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic arch morphology  (IAGP)
abnormal auditory brainstem response  (IEA)
abnormal basisphenoid bone morphology  (IAGP)
abnormal body wall morphology  (IEA)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cell differentiation  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal cochlear ganglion morphology  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal common crus morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal embryo size  (IEA)
abnormal endolymphatic duct morphology  (IAGP)
abnormal epaxial muscle morphology  (IAGP)
abnormal external auditory canal morphology  (IAGP)
abnormal extraocular muscle morphology  (IAGP)
abnormal facial morphology  (IEA)
abnormal facial nerve morphology  (IAGP)
abnormal first pharyngeal pouch morphology  (IAGP)
abnormal geniculate ganglion morphology  (IAGP)
abnormal head shape  (IEA)
abnormal hyoid bone lesser horn morphology  (IAGP)
abnormal hyoid bone morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal inner ear morphology  (IAGP)
abnormal ischium morphology  (IAGP)
abnormal jaw morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lateral semicircular canal morphology  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal mitotic spindle morphology  (IAGP)
abnormal orientation of cochlear hair cell stereociliary bundles  (IAGP)
abnormal otic vesicle development  (IAGP)
abnormal outer ear morphology  (IEA)
abnormal palate development  (IAGP)
abnormal posterior semicircular canal morphology  (IAGP)
abnormal pterygoid process morphology  (IAGP)
abnormal pubis morphology  (IAGP)
abnormal pulmonary artery morphology  (IAGP)
abnormal semicircular canal ampulla morphology  (IAGP)
abnormal semicircular canal morphology  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal sternocostal joint morphology  (IAGP)
abnormal temporal bone morphology  (IAGP)
abnormal thyroid cartilage morphology  (IAGP)
abnormal tympanic membrane morphology  (IAGP)
abnormal ureteric bud morphology  (IAGP)
abnormal utricle morphology  (IAGP)
abnormal vestibular labyrinth morphology  (IAGP)
abnormal vestibular saccule morphology  (IAGP)
abnormal vestibulocochlear nerve morphology  (IAGP)
abnormal zygomatic bone morphology  (IAGP)
absent auditory bulla  (IAGP)
absent cochlea  (IAGP)
absent endolymphatic duct  (IAGP)
absent external auditory canal  (IAGP)
absent hypaxial muscle  (IAGP)
absent inner ear  (IAGP)
absent inner ear vestibule  (IAGP)
absent kidney  (IAGP)
absent lateral semicircular canal  (IAGP)
absent malleus processus brevis  (IAGP)
absent maxilla  (IAGP)
absent organ of Corti  (IAGP)
absent outer ear  (IAGP)
absent parathyroid glands  (IAGP)
absent petrosal ganglion  (IAGP)
absent posterior semicircular canal  (IAGP)
absent premaxilla  (IAGP)
absent stapes  (IAGP)
absent thyroid gland isthmus  (IAGP)
absent tympanic cavity  (IAGP)
absent ureter  (IAGP)
absent ureteric bud  (IAGP)
absent vestibular ganglion  (IAGP)
absent vestibular saccule  (IAGP)
anotia  (IAGP)
athymia  (IAGP)
cervical vertebral fusion  (IAGP)
circling  (IAGP)
cleft secondary palate  (IAGP)
cochlear ganglion degeneration  (IAGP)
conductive hearing loss  (IAGP)
deafness  (IAGP)
decreased cell proliferation  (IAGP)
decreased cochlear coiling  (IAGP)
decreased cochlear inner hair cell number  (IAGP)
decreased cochlear outer hair cell number  (IAGP)
decreased lateral semicircular canal size  (IAGP)
decreased maxillary shelf size  (IAGP)
decreased otic epithelial cell proliferation  (IAGP)
decreased outer hair cell stereocilia number  (IAGP)
decreased palatine bone horizontal plate size  (IAGP)
decreased posterior semicircular canal size  (IAGP)
decreased superior semicircular canal size  (IAGP)
decreased tympanic ring size  (IAGP)
decreased vestibular hair cell number  (IAGP)
double outlet right ventricle  (IAGP)
eyelids open at birth  (IAGP)
facial muscle hypoplasia  (IAGP)
female infertility  (IAGP)
fusion of middle ear ossicles  (IAGP)
head bobbing  (IAGP)
impaired branching involved in ureteric bud morphogenesis  (IAGP)
increased apoptosis  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased cochlear outer hair cell number  (IAGP)
increased metanephric mesenchyme apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased otic epithelial cell apoptosis  (IAGP)
interrupted aortic arch  (IAGP)
large nasal septum  (IAGP)
mandible hypoplasia  (IAGP)
microcephaly  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosis  (IAGP)
persistent ultimobranchial bodies  (IAGP)
pituitary gland hypoplasia  (IAGP)
preauricular pit  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
renal hypoplasia  (IAGP)
retroesophageal right subclavian artery  (IAGP)
rib fusion  (IAGP)
right aortic arch  (IAGP)
short endolymphatic duct  (IAGP)
single kidney  (IAGP)
small cranium  (IAGP)
small lung  (IAGP)
small otic vesicle  (IAGP)
small pituitary gland  (IAGP)
small vestibular saccule  (IAGP)
thyroid gland hypoplasia  (IAGP)
tongue muscle hypoplasia  (IAGP)
vascular ring  (IAGP)
References

Additional References at PubMed
PMID:9006082   PMID:9020840   PMID:9195991   PMID:9342347   PMID:9817915   PMID:9851982   PMID:9853969   PMID:9887327   PMID:9915577   PMID:10072433   PMID:10349636   PMID:10471511  
PMID:10490620   PMID:10603348   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11688560   PMID:11700312   PMID:11734542   PMID:11804780   PMID:11950062   PMID:12050119   PMID:12070080  
PMID:12072567   PMID:12477932   PMID:12642503   PMID:12729564   PMID:12783782   PMID:12874121   PMID:14517553   PMID:14628042   PMID:14628052   PMID:14695375   PMID:14973294   PMID:15130495  
PMID:15141091   PMID:15226428   PMID:15242798   PMID:15492887   PMID:15496442   PMID:15499560   PMID:15817220   PMID:15905075   PMID:16018995   PMID:16024294   PMID:16054034   PMID:16109395  
PMID:16141072   PMID:16141073   PMID:16319112   PMID:16319116   PMID:16442091   PMID:16488112   PMID:16530750   PMID:16790474   PMID:16797546   PMID:16870172   PMID:16916509   PMID:16990542  
PMID:17036046   PMID:17098221   PMID:17382312   PMID:17537792   PMID:17785448   PMID:18219393   PMID:18287559   PMID:18424556   PMID:18485340   PMID:18678597   PMID:18759246   PMID:18787044  
PMID:18816442   PMID:18836772   PMID:19027001   PMID:19234442   PMID:19235731   PMID:19591821   PMID:19715689   PMID:19716816   PMID:19877281   PMID:20040500   PMID:20110314   PMID:20439720  
PMID:20503367   PMID:20589882   PMID:20589901   PMID:20727173   PMID:20736290   PMID:20843830   PMID:20869363   PMID:20956555   PMID:21128305   PMID:21129374   PMID:21267068   PMID:21281623  
PMID:21350016   PMID:21364285   PMID:21386911   PMID:21533152   PMID:21858105   PMID:21873635   PMID:21936910   PMID:21963425   PMID:21968101   PMID:22182523   PMID:22267199   PMID:22340499  
PMID:22510988   PMID:22511595   PMID:22513373   PMID:23263983   PMID:23614009   PMID:23636126   PMID:23895934   PMID:23974041   PMID:24067355   PMID:24301466   PMID:24378336   PMID:24440154  
PMID:24489909   PMID:24550112   PMID:24598167   PMID:24752894   PMID:25458011   PMID:25617721   PMID:25641696   PMID:25803581   PMID:25816987   PMID:25859222   PMID:25903664   PMID:26116176  
PMID:26550799   PMID:27820600   PMID:28346476   PMID:28455376   PMID:28492243   PMID:28892484   PMID:29140246   PMID:29509905   PMID:30377232   PMID:30561639   PMID:30635573   PMID:31142573  
PMID:31351040   PMID:31956913   PMID:31988190   PMID:32715478   PMID:33298461  


Genomics

Comparative Map Data
Eya1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,239,177 - 14,381,259 (-)NCBIGRCm39mm39
GRCm39 Ensembl114,239,178 - 14,380,459 (-)Ensembl
GRCm38114,168,953 - 14,311,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,168,954 - 14,310,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,159,039 - 14,300,280 (-)NCBIGRCm37mm9NCBIm37
MGSCv36114,154,172 - 14,295,413 (-)NCBImm8
Celera114,109,695 - 14,251,151 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.31NCBI
EYA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl871,197,433 - 71,592,025 (-)EnsemblGRCh38hg38GRCh38
GRCh38871,197,433 - 71,548,104 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37872,109,668 - 72,460,329 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36872,272,222 - 72,437,021 (-)NCBINCBI36hg18NCBI36
Build 34872,272,221 - 72,437,021NCBI
Celera868,106,627 - 68,271,433 (-)NCBI
Cytogenetic Map8q13.3NCBI
HuRef867,603,371 - 67,768,504 (-)NCBIHuRef
CHM1_1872,164,260 - 72,329,031 (-)NCBICHM1_1
Eya1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.254,863,501 - 5,101,483 (+)NCBI
Rnor_6.0 Ensembl54,373,626 - 4,513,142 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.054,275,728 - 4,495,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.054,252,745 - 4,487,853 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.454,132,825 - 4,276,837 (+)NCBIRGSC3.4rn4RGSC3.4
Celera54,454,356 - 4,554,997 (+)NCBICelera
Celera54,581,829 - 4,692,568 (+)NCBICelera
Cytogenetic Map5q11NCBI
Eya1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554448,495,530 - 8,655,100 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554448,336,071 - 8,655,041 (+)NCBIChiLan1.0ChiLan1.0
EYA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1869,387,769 - 69,551,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl869,387,769 - 69,551,829 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0867,728,057 - 68,060,069 (-)NCBIMhudiblu_PPA_v0panPan3
EYA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12920,176,306 - 20,595,131 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2920,177,014 - 20,525,653 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2920,436,698 - 20,855,121 (-)NCBI
ROS_Cfam_1.02920,275,380 - 20,693,971 (-)NCBI
UMICH_Zoey_3.12920,325,900 - 20,743,158 (-)NCBI
UNSW_CanFamBas_1.02920,378,421 - 20,796,035 (-)NCBI
UU_Cfam_GSD_1.02920,660,077 - 21,078,705 (-)NCBI
Eya1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530358,739,647 - 59,053,061 (+)NCBI
SpeTri2.0NW_004936648395,526 - 546,705 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EYA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl463,970,511 - 64,328,105 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1463,970,939 - 64,328,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2469,915,648 - 69,943,761 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EYA1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1866,902,961 - 67,238,149 (-)NCBI
ChlSab1.1 Ensembl866,902,972 - 67,060,567 (-)Ensembl
Eya1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474419,782,174 - 19,975,496 (+)NCBI

Position Markers
RH131160  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,169,052 - 14,169,275UniSTSGRCm38
MGSCv37114,159,133 - 14,159,356UniSTSGRCm37
Celera114,109,789 - 14,110,012UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
C86010  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,191,748 - 14,191,860UniSTSGRCm38
MGSCv37114,181,829 - 14,181,941UniSTSGRCm37
Celera114,132,665 - 14,132,777UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
Whitehead/MRC_RH1243.62UniSTS
Eya1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,252,590 - 14,253,046UniSTSGRCm38
Celera114,193,545 - 14,194,001UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
cM Map110.4UniSTS
35.MMHAP50FLD5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,274,992 - 14,275,152UniSTSGRCm38
MGSCv37114,265,073 - 14,265,233UniSTSGRCm37
Celera114,215,872 - 14,216,032UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
Whitehead_YAC1 UniSTS
D1Mit430  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,281,275 - 14,281,387UniSTSGRCm38
MGSCv37114,271,356 - 14,271,468UniSTSGRCm37
Celera114,222,167 - 14,222,283UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.0UniSTS
Whitehead Genetic16.6UniSTS
Whitehead/MRC_RH1249.16UniSTS
Whitehead_YAC1 UniSTS
U61110  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38114,170,827 - 14,170,921UniSTSGRCm38
MGSCv37114,160,908 - 14,161,002UniSTSGRCm37
Celera114,111,564 - 14,111,658UniSTS
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
Whitehead/MRC_RH1240.69UniSTS
Eya1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1A3UniSTS
cM Map110.4UniSTS
Eya1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1A3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412226Alpq4_malcohol preference QTL 4 (mouse)Not determined1122906465Mouse
1301891Alcp25_malcohol preference locus 25 (mouse)Not determined1125132961Mouse
1300834Cia20_mcollagen induced arthritis 20 (mouse)Not determined1125132961Mouse
1301482Morph1_mmorphine antinociception 1 (mouse)Not determined1130297523Mouse
1301275Sle10_msystematic lupus erythematosus susceptibility 10 (mouse)Not determined1281197036812128Mouse
1301370Adip1_madiposity 1 (mouse)Not determined1281197036812128Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1387139637871663Mouse
10043970Obq23_mobesity QTL 23 (mouse)Not determined1494244138942441Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1963436143634520Mouse
14700685Civq2_mcerebral infarct volume QTL 2 (mouse)11130140145301401Mouse
38501065Nociq4_mnociceptive sensitivity QTL 4 (mouse)11195484515072061Mouse
4141646Fecq3_mfecundity QTL 3 (mouse)Not determined11284669626478604Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1689
Count of miRNA genes:407
Interacting mature miRNAs:458
Transcripts:ENSMUST00000027066, ENSMUST00000080664, ENSMUST00000168081
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001310459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011238344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011238346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC156988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF097544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ007995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U61110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027066   ⟹   ENSMUSP00000027066
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,168,954 - 14,310,200 (-)Ensembl
RefSeq Acc Id: ENSMUST00000080664   ⟹   ENSMUSP00000079493
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,169,666 - 14,310,119 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168081   ⟹   ENSMUSP00000126383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,168,958 - 14,310,235 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185329
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,301,204 - 14,310,051 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185453   ⟹   ENSMUSP00000141072
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,270,707 - 14,304,628 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187790   ⟹   ENSMUSP00000139542
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,270,775 - 14,309,836 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188857   ⟹   ENSMUSP00000140171
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,252,600 - 14,304,619 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189526   ⟹   ENSMUSP00000140619
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,207,926 - 14,231,492 (-)Ensembl
RefSeq Acc Id: ENSMUST00000190337   ⟹   ENSMUSP00000141112
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl114,170,643 - 14,304,570 (-)Ensembl
RefSeq Acc Id: NM_001252192   ⟹   NP_001239121
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,182 - 14,380,423 (-)NCBI
GRCm38114,168,958 - 14,310,199 (-)NCBI
Celera114,109,695 - 14,251,151 (-)ENTREZGENE
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001310459   ⟹   NP_001297388
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,182 - 14,380,423 (-)NCBI
GRCm38114,168,958 - 14,310,199 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010164   ⟹   NP_034294
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,182 - 14,380,423 (-)NCBI
GRCm38114,168,958 - 14,310,199 (-)NCBI
MGSCv37114,159,039 - 14,300,280 (-)RGD
Celera114,109,695 - 14,251,151 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006495446   ⟹   XP_006495509
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,172 (-)NCBI
GRCm38114,168,953 - 14,304,970 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006495451   ⟹   XP_006495514
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,381,259 (-)NCBI
GRCm38114,168,953 - 14,311,035 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006495452   ⟹   XP_006495515
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,381,259 (-)NCBI
GRCm38114,168,953 - 14,311,035 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011238344   ⟹   XP_011236646
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,381,259 (-)NCBI
GRCm38114,168,953 - 14,311,035 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011238346   ⟹   XP_011236648
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,174 (-)NCBI
GRCm38114,168,953 - 14,305,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315348   ⟹   XP_017170837
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,171 (-)NCBI
GRCm38114,168,953 - 14,304,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315381   ⟹   XP_017170870
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,174 (-)NCBI
GRCm38114,168,953 - 14,305,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315414   ⟹   XP_017170903
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,381,259 (-)NCBI
GRCm38114,168,953 - 14,311,035 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315422   ⟹   XP_017170911
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,170 (-)NCBI
GRCm38114,168,953 - 14,304,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247470   ⟹   XP_030103330
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,375,172 (-)NCBI
GRCm38114,168,953 - 14,304,970 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159644   ⟹   XP_036015537
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,253,445 - 14,381,259 (-)NCBI
RefSeq Acc Id: XM_036159662   ⟹   XP_036015555
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,344,827 (-)NCBI
RefSeq Acc Id: XM_036159667   ⟹   XP_036015560
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,278,145 - 14,381,259 (-)NCBI
RefSeq Acc Id: XM_036159675   ⟹   XP_036015568
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,278,155 - 14,381,259 (-)NCBI
RefSeq Acc Id: XR_001780756
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,239,177 - 14,381,259 (-)NCBI
GRCm38114,168,953 - 14,311,035 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001239121 (Get FASTA)   NCBI Sequence Viewer  
  NP_001297388 (Get FASTA)   NCBI Sequence Viewer  
  NP_034294 (Get FASTA)   NCBI Sequence Viewer  
  XP_006495509 (Get FASTA)   NCBI Sequence Viewer  
  XP_006495514 (Get FASTA)   NCBI Sequence Viewer  
  XP_006495515 (Get FASTA)   NCBI Sequence Viewer  
  XP_011236646 (Get FASTA)   NCBI Sequence Viewer  
  XP_011236648 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170837 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170870 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170903 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170911 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103330 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015537 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015555 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015560 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015568 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB48017 (Get FASTA)   NCBI Sequence Viewer  
  AAD19355 (Get FASTA)   NCBI Sequence Viewer  
  AAH60260 (Get FASTA)   NCBI Sequence Viewer  
  AAH66860 (Get FASTA)   NCBI Sequence Viewer  
  BAC31251 (Get FASTA)   NCBI Sequence Viewer  
  BAE36732 (Get FASTA)   NCBI Sequence Viewer  
  CAA07818 (Get FASTA)   NCBI Sequence Viewer  
  CAA71312 (Get FASTA)   NCBI Sequence Viewer  
  EDL14327 (Get FASTA)   NCBI Sequence Viewer  
  P97767 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_034294   ⟸   NM_010164
- Peptide Label: isoform 1
- UniProtKB: F6YST4 (UniProtKB/TrEMBL),   Q6PAJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001239121   ⟸   NM_001252192
- Peptide Label: isoform 2
- UniProtKB: Q6PAJ8 (UniProtKB/TrEMBL),   Q8C9D0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006495515   ⟸   XM_006495452
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006495514   ⟸   XM_006495451
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006495509   ⟸   XM_006495446
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011236646   ⟸   XM_011238344
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011236648   ⟸   XM_011238346
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017170903   ⟸   XM_017315414
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017170870   ⟸   XM_017315381
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017170911   ⟸   XM_017315422
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017170837   ⟸   XM_017315348
- Peptide Label: isoform X3
- UniProtKB: P97767 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001297388   ⟸   NM_001310459
- Peptide Label: isoform 3
- UniProtKB: P97767 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030103330   ⟸   XM_030247470
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000027066   ⟸   ENSMUST00000027066
RefSeq Acc Id: ENSMUSP00000141072   ⟸   ENSMUST00000185453
RefSeq Acc Id: ENSMUSP00000141112   ⟸   ENSMUST00000190337
RefSeq Acc Id: ENSMUSP00000140171   ⟸   ENSMUST00000188857
RefSeq Acc Id: ENSMUSP00000079493   ⟸   ENSMUST00000080664
RefSeq Acc Id: ENSMUSP00000139542   ⟸   ENSMUST00000187790
RefSeq Acc Id: ENSMUSP00000126383   ⟸   ENSMUST00000168081
RefSeq Acc Id: ENSMUSP00000140619   ⟸   ENSMUST00000189526
RefSeq Acc Id: XP_036015555   ⟸   XM_036159662
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036015537   ⟸   XM_036159644
- Peptide Label: isoform X6
RefSeq Acc Id: XP_036015560   ⟸   XM_036159667
- Peptide Label: isoform X9
RefSeq Acc Id: XP_036015568   ⟸   XM_036159675
- Peptide Label: isoform X10

Promoters
RGD ID:6817695
Promoter ID:MM_KWN:160
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   MEF_B6
Transcripts:ENSMUST00000027066,   ENSMUST00000080664,   NM_010164,   UC007AIY.1,   UC007AIZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36114,299,764 - 14,300,264 (-)MPROMDB
RGD ID:6873210
Promoter ID:EPDNEW_M56
Type:initiation region
Name:Eya1_1
Description:Mus musculus EYA transcriptional coactivator and phosphatase1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38114,304,632 - 14,304,692EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109344 AgrOrtholog
Ensembl Genes ENSMUSG00000025932 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000027066 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000079493 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000126383 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000139542 UniProtKB/TrEMBL
  ENSMUSP00000140171 UniProtKB/TrEMBL
  ENSMUSP00000140619 UniProtKB/TrEMBL
  ENSMUSP00000141072 UniProtKB/TrEMBL
  ENSMUSP00000141112 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027066 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000080664 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000168081 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000185453 UniProtKB/TrEMBL
  ENSMUST00000187790 UniProtKB/TrEMBL
  ENSMUST00000188857 UniProtKB/TrEMBL
  ENSMUST00000189526 UniProtKB/TrEMBL
  ENSMUST00000190337 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.12350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EYA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EYA_dom_metazoan UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EYA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EYA_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Eyes_absent_h1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14048 UniProtKB/Swiss-Prot
MGD MGI:109344 ENTREZGENE
NCBI Gene 14048 ENTREZGENE
PANTHER PTHR10190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10190:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eya1 PhenoGen
TIGRFAMs EYA-cons_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WNY3_MOUSE UniProtKB/TrEMBL
  A0A087WQF4_MOUSE UniProtKB/TrEMBL
  A0A087WRG6_MOUSE UniProtKB/TrEMBL
  A0A087WSJ4_MOUSE UniProtKB/TrEMBL
  EYA1_MOUSE UniProtKB/Swiss-Prot
  F6YST4 ENTREZGENE, UniProtKB/TrEMBL
  P97767 ENTREZGENE
  Q3TSE3_MOUSE UniProtKB/TrEMBL
  Q6NXW1_MOUSE UniProtKB/TrEMBL
  Q6PAJ8 ENTREZGENE, UniProtKB/TrEMBL
  Q8C9D0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7B3B8 UniProtKB/TrEMBL
  G5E864 UniProtKB/Swiss-Prot
  O08818 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Eya1  EYA transcriptional coactivator and phosphatase 1    eyes absent 1 homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED