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Gene: EYA1 (EYA transcriptional coactivator and phosphatase 1) Homo sapiens
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Symbol: EYA1
Name: EYA transcriptional coactivator and phosphatase 1
Description: Exhibits protein tyrosine phosphatase activity. Involved in several processes, including histone dephosphorylation; positive regulation of DNA repair; and response to ionizing radiation. Localizes to the cytoplasm and nuclear body. Implicated in branchiootic syndrome and branchiootorenal syndrome. Biomarker of mitochondrial myopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BOP; BOR; BOS1; eyes absent homolog 1; MGC141875; OFC1
Orthologs:
Mus musculus (house mouse) : Eya1 (EYA transcriptional coactivator and phosphatase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eya1 (EYA transcriptional coactivator and phosphatase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eya1 (EYA transcriptional coactivator and phosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EYA1 (EYA transcriptional coactivator and phosphatase 1)
Canis lupus familiaris (dog) : EYA1 (EYA transcriptional coactivator and phosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eya1 (EYA transcriptional coactivator and phosphatase 1)
Sus scrofa (pig) : EYA1 (EYA transcriptional coactivator and phosphatase 1)
Chlorocebus sabaeus (green monkey) : EYA1 (EYA transcriptional coactivator and phosphatase 1)
Heterocephalus glaber (naked mole-rat) : Eya1 (EYA transcriptional coactivator and phosphatase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl871,197,433 - 71,592,025 (-)Ensembl
GRCh38871,197,433 - 71,548,104 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37872,109,668 - 72,459,888 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36872,272,222 - 72,437,021 (-)NCBINCBI36hg18NCBI36
Build 34872,272,221 - 72,437,021NCBI
Celera868,106,627 - 68,271,433 (-)NCBI
Cytogenetic Map8q13.3NCBI
HuRef867,603,371 - 67,768,504 (-)NCBIHuRef
CHM1_1872,164,260 - 72,329,031 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on EYA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317054
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.