Prkab2 (protein kinase AMP-activated non-catalytic subunit beta 2) - Rat Genome Database

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Gene: Prkab2 (protein kinase AMP-activated non-catalytic subunit beta 2) Heterocephalus glaber
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Symbol: Prkab2
Name: protein kinase AMP-activated non-catalytic subunit beta 2
RGD ID: 18920951
Description: ENCODES a protein that exhibits AMP-activated protein kinase activity (ortholog); enzyme binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to nutrient levels (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); cataract 46 juvenile-onset (ortholog); chromosome 1q21.1 deletion syndrome (ortholog); FOUND IN apical plasma membrane (ortholog); cAMP-dependent protein kinase complex (ortholog); nucleotide-activated protein kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 5'-AMP-activated protein kinase subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477216,110,294 - 16,127,119 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477216,110,805 - 16,127,221 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Prkab2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477216,110,294 - 16,127,119 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477216,110,805 - 16,127,221 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRKAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,155,106 - 147,172,470 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1147,155,106 - 147,172,550 (-)EnsemblGRCh38hg38GRCh38
GRCh371146,626,685 - 146,644,049 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361145,093,309 - 145,110,753 (-)NCBINCBI36Build 36hg18NCBI36
Build 341143,851,502 - 143,868,945NCBI
Celera1122,340,718 - 122,358,162 (+)NCBICelera
Cytogenetic Map1q21.1NCBI
HuRef1120,039,190 - 120,056,673 (-)NCBIHuRef
CHM1_11148,523,232 - 148,540,715 (-)NCBICHM1_1
T2T-CHM13v2.01147,635,939 - 147,653,299 (+)NCBIT2T-CHM13v2.0
Prkab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39397,565,527 - 97,581,128 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl397,565,509 - 97,581,128 (+)EnsemblGRCm39 Ensembl
GRCm38397,658,211 - 97,673,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl397,658,193 - 97,673,812 (+)EnsemblGRCm38mm10GRCm38
MGSCv37397,462,135 - 97,477,006 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36397,743,617 - 97,758,488 (+)NCBIMGSCv36mm8
Celera399,057,874 - 99,072,745 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.25NCBI
Prkab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82187,946,008 - 187,961,615 (+)NCBIGRCr8
mRatBN7.22185,257,218 - 185,272,846 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2185,257,213 - 185,269,872 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2192,905,393 - 192,917,612 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02190,713,236 - 190,725,438 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02185,538,007 - 185,550,226 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02199,831,990 - 199,847,623 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2199,831,990 - 199,847,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,309,807 - 219,325,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,498,430 - 192,510,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12192,461,183 - 192,473,369 (+)NCBI
Celera2177,749,772 - 177,761,966 (+)NCBICelera
Cytogenetic Map2q34NCBI
Prkab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555681,252,736 - 1,279,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555681,253,331 - 1,279,761 (+)NCBIChiLan1.0ChiLan1.0
PRKAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21102,556,601 - 102,574,428 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11102,144,935 - 102,162,775 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01122,577,308 - 122,595,083 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11112,934,877 - 112,952,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1112,934,877 - 112,952,364 (+)Ensemblpanpan1.1panPan2
PRKAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11757,614,499 - 57,630,041 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1757,616,451 - 57,630,041 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1757,138,994 - 57,154,977 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01758,608,987 - 58,624,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1758,547,205 - 58,625,036 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11757,507,665 - 57,523,856 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01757,555,486 - 57,571,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01758,281,440 - 58,297,432 (-)NCBIUU_Cfam_GSD_1.0
LOC101973983
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050583,224,028 - 3,239,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493695377,688 - 93,374 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493695377,671 - 93,383 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4100,378,071 - 100,394,338 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14100,378,047 - 100,394,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24110,207,633 - 110,223,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKAB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603815,067,417 - 15,083,027 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006570   ⟹   ENSHGLP00000006488
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477216,110,294 - 16,127,119 (-)Ensembl
RefSeq Acc Id: XM_004853879   ⟹   XP_004853936
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477216,110,805 - 16,127,221 (-)NCBI
RefSeq Acc Id: XM_013075573   ⟹   XP_012931027
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477216,110,805 - 16,127,221 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004853936 (Get FASTA)   NCBI Sequence Viewer  
  XP_012931027 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB06116 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006488
  ENSHGLP00000033622
  ENSHGLP00100048589
RefSeq Acc Id: XP_004853936   ⟸   XM_004853879
- Peptide Label: isoform X1
- UniProtKB: G5BA05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012931027   ⟸   XM_013075573
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R0J8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006488   ⟸   ENSHGLT00000006570


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004744 Ensembl, ENTREZGENE
  ENSHGLG00000033772 UniProtKB/TrEMBL
  ENSHGLG00100049772 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006570 ENTREZGENE
  ENSHGLT00000084898 UniProtKB/TrEMBL
  ENSHGLT00100047984 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  6.20.250.60 UniProtKB/TrEMBL
InterPro AMPK1_CBM UniProtKB/TrEMBL
  ASC_dom UniProtKB/TrEMBL
  ASC_dom_sf UniProtKB/TrEMBL
  CRP1_MDG1_kinase UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
KEGG Report hgl:101720100 UniProtKB/TrEMBL
NCBI Gene Prkab2 ENTREZGENE
PANTHER 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT UniProtKB/TrEMBL
  5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 UniProtKB/TrEMBL
Pfam AMPK1_CBM UniProtKB/TrEMBL
  AMPKBI UniProtKB/TrEMBL
SMART AMPKBI UniProtKB/TrEMBL
Superfamily-SCOP SSF160219 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0AAX6R0J8 ENTREZGENE, UniProtKB/TrEMBL
  G5BA05 ENTREZGENE, UniProtKB/TrEMBL