Ldaf1 (lipid droplet assembly factor 1) - Rat Genome Database

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Gene: Ldaf1 (lipid droplet assembly factor 1) Heterocephalus glaber
Analyze
Symbol: Ldaf1
Name: lipid droplet assembly factor 1 (Ensembl:transmembrane protein 159)
RGD ID: 18912391
Description: INVOLVED IN lipid droplet formation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); lipid droplet (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Promethin; Tmem159; transmembrane protein 159
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,243,806 - 7,259,638 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,244,332 - 7,259,105 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Ldaf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,243,806 - 7,259,638 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,244,332 - 7,259,105 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LDAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381621,158,674 - 21,180,616 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1621,158,377 - 21,180,616 (+)EnsemblGRCh38hg38GRCh38
GRCh371621,169,995 - 21,191,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,077,501 - 21,099,431 (+)NCBINCBI36Build 36hg18NCBI36
Celera1620,479,745 - 20,501,782 (+)NCBICelera
Cytogenetic Map16p12.3NCBI
HuRef1619,705,255 - 19,727,143 (+)NCBIHuRef
CHM1_11621,257,154 - 21,279,197 (+)NCBICHM1_1
T2T-CHM13v2.01621,089,598 - 21,111,555 (+)NCBIT2T-CHM13v2.0
Ldaf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,701,599 - 119,720,212 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7119,701,576 - 119,720,215 (+)EnsemblGRCm39 Ensembl
GRCm387120,102,342 - 120,120,987 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7120,102,353 - 120,120,992 (+)EnsemblGRCm38mm10GRCm38
MGSCv377127,245,940 - 127,264,500 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367119,893,575 - 119,912,135 (+)NCBIMGSCv36mm8
Celera7120,011,610 - 120,030,538 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map764.37NCBI
Ldaf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,915,919 - 183,934,374 (+)NCBIGRCr8
mRatBN7.21174,484,438 - 174,503,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,484,447 - 174,503,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1182,802,178 - 182,820,613 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01189,988,218 - 190,006,655 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,721,980 - 182,740,658 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,870,596 - 189,889,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,870,622 - 189,889,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,800,304 - 196,819,295 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1172,234,268 - 172,252,725 (+)NCBICelera
Cytogenetic Map1q36NCBI
Ldaf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955493368,399 - 386,716 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955493368,399 - 386,651 (+)NCBIChiLan1.0ChiLan1.0
LDAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21822,325,762 - 22,348,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,846,269 - 26,869,348 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,227,549 - 17,250,533 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11621,187,479 - 21,210,432 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1621,187,479 - 21,210,432 (+)Ensemblpanpan1.1panPan2
LDAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,254,281 - 24,268,129 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,209,125 - 24,267,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha625,693,511 - 25,705,828 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0624,407,145 - 24,419,464 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl624,358,101 - 24,419,328 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1624,210,514 - 24,222,833 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0624,102,683 - 24,117,837 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0624,489,635 - 24,501,962 (-)NCBIUU_Cfam_GSD_1.0
Ldaf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344118,258,832 - 118,274,339 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365016,356,687 - 6,373,572 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365016,356,709 - 6,369,010 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl324,876,637 - 24,910,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1324,876,631 - 24,910,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2325,776,868 - 25,782,674 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LDAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,278,601 - 19,301,339 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,278,646 - 19,301,959 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606810,578,441 - 10,601,833 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020804   ⟹   ENSHGLP00000020602
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247827,243,806 - 7,259,638 (+)Ensembl
RefSeq Acc Id: XM_004855902   ⟹   XP_004855959
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247827,244,332 - 7,259,105 (+)NCBI
RefSeq Acc Id: XM_021237295   ⟹   XP_021092954
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247827,244,332 - 7,259,105 (+)NCBI
RefSeq Acc Id: XM_021237296   ⟹   XP_021092955
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247827,244,332 - 7,259,105 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855959 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092954 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092955 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13205 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020602
  ENSHGLP00000045664
  ENSHGLP00100038787
  ENSHGLP00100055426
  ENSHGLP00100058311
GenBank Protein JAN96652 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021092954   ⟸   XM_021237295
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004855959   ⟸   XM_004855902
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J2V2 (UniProtKB/TrEMBL),   G5AKF8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092955   ⟸   XM_021237296
- Peptide Label: isoform X3
- UniProtKB: G5BV94 (UniProtKB/TrEMBL),   G5AKF8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020602   ⟸   ENSHGLT00000020804


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014735 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100010133 UniProtKB/TrEMBL
  ENSHGLG00100040860 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020804 ENTREZGENE
  ENSHGLT00000056774 UniProtKB/TrEMBL
  ENSHGLT00100043583 UniProtKB/TrEMBL
  ENSHGLT00100053769 UniProtKB/TrEMBL
  ENSHGLT00100055152 UniProtKB/TrEMBL
InterPro LDAF1 UniProtKB/TrEMBL
KEGG Report hgl:101705325 UniProtKB/TrEMBL
NCBI Gene Tmem159 ENTREZGENE
PANTHER LIPID DROPLET ASSEMBLY FACTOR 1 UniProtKB/TrEMBL
  PTHR14275 UniProtKB/TrEMBL
Pfam Promethin UniProtKB/TrEMBL
UniProt A0A0P6J2V2 ENTREZGENE, UniProtKB/TrEMBL
  G5AKF8 ENTREZGENE, UniProtKB/TrEMBL
  G5BV94 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-16 Ldaf1  lipid droplet assembly factor 1  Tmem159  transmembrane protein 159  Symbol and/or name change 5135510 APPROVED