Ghrhr (growth hormone releasing hormone receptor) - Rat Genome Database

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Gene: Ghrhr (growth hormone releasing hormone receptor) Heterocephalus glaber
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Symbol: Ghrhr
Name: growth hormone releasing hormone receptor
RGD ID: 18911598
Description: ENCODES a protein that exhibits growth hormone-releasing hormone receptor activity (ortholog); INVOLVED IN activation of adenylate cyclase activity (ortholog); adenohypophysis development (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); disorder of sexual development (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); nuclear inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: growth hormone-releasing hormone receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624783200,935 - 214,453 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624783200,940 - 214,373 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ghrhr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624783200,935 - 214,453 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624783200,940 - 214,373 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
GHRHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,963,953 - 30,979,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,938,669 - 30,993,254 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37731,003,568 - 31,019,143 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,970,161 - 30,985,668 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34730,776,875 - 30,788,828NCBI
Celera730,992,840 - 31,008,351 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,885,854 - 30,901,378 (+)NCBIHuRef
CHM1_1731,003,564 - 31,019,092 (+)NCBICHM1_1
T2T-CHM13v2.0731,101,596 - 31,117,172 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2731,053,140 - 31,068,651 (+)NCBI
Ghrhr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39655,353,204 - 55,365,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl655,353,280 - 55,365,515 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38655,376,295 - 55,388,530 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl655,376,295 - 55,388,530 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37655,326,289 - 55,338,524 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36655,305,940 - 55,317,897 (+)NCBIMGSCv36mm8
Celera655,910,067 - 55,922,286 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
Ghrhr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,830,345 - 85,863,127 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl485,830,486 - 85,863,127 (+)EnsemblGRCr8
mRatBN7.2484,498,159 - 84,532,851 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl484,500,212 - 84,532,776 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx489,718,589 - 89,754,998 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0485,493,999 - 85,530,402 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,899,789 - 83,936,121 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd487,064,979 - 87,097,649 (+)NCBI
Lyon_Normotensive484,749,089 - 84,781,733 (+)NCBI
Lyon_Hypertensive485,266,273 - 85,298,917 (+)NCBI
F344_StmMcwi485,142,791 - 85,179,178 (+)NCBI
Rnor_6.0485,587,321 - 85,602,389 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,588,595 - 85,601,666 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.04150,221,064 - 150,253,706 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4484,135,530 - 84,148,503 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera479,386,911 - 79,400,313 (+)NCBICelera
RGSC_v3.1484,421,996 - 84,434,974 (+)NCBI
Cytogenetic Map4q24NCBI
Ghrhr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,102,367 - 32,115,080 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495541032,084,210 - 32,114,844 (+)NCBIChiLan1.0ChiLan1.0
GHRHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2635,775,238 - 35,790,875 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1784,099,966 - 84,115,603 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0731,582,134 - 31,592,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1731,701,641 - 31,712,200 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl731,696,914 - 31,712,200 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
GHRHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11443,626,862 - 43,638,737 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1443,626,845 - 43,638,753 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1443,059,230 - 43,070,721 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01443,567,602 - 43,579,114 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1443,567,473 - 43,579,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11443,683,226 - 43,694,708 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01443,359,784 - 43,371,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01443,721,032 - 43,732,545 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ghrhr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap12144,609,845 - 144,624,990 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_02440511887,980,695 - 87,991,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364787,188,826 - 7,201,932 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364787,188,826 - 7,202,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHRHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,030,510 - 42,046,184 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11842,030,505 - 42,046,178 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21846,427,131 - 46,436,821 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHRHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12130,830,781 - 30,845,630 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366604277,286,895 - 77,301,754 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.12127,402,765 - 27,417,536 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2127,404,886 - 27,417,521 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Ghrhr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1685,684,312 - 85,697,608 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000010954   ⟹   ENSHGLP00000010832
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624783200,940 - 214,373 (+)Ensembl
RefSeq Acc Id: XM_004856289   ⟹   XP_004856346
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624783200,946 - 214,453 (+)NCBI
RefSeq Acc Id: XM_021237627   ⟹   XP_021093286
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624783200,943 - 214,453 (+)NCBI
RefSeq Acc Id: XM_021237628   ⟹   XP_021093287
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624783200,939 - 214,453 (+)NCBI
RefSeq Acc Id: XM_021237629   ⟹   XP_021093288
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624783200,935 - 214,453 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856346 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093286 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093287 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010832
RefSeq Acc Id: XP_021093288   ⟸   XM_021237629
- Peptide Label: isoform X4
- UniProtKB: A0AAX6R9D6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093287   ⟸   XM_021237628
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R9M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093286   ⟸   XM_021237627
- Peptide Label: isoform X1
- UniProtKB: A0AAX6R8T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856346   ⟸   XM_004856289
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PQ11 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010832   ⟸   ENSHGLT00000010954


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007773 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010954 ENTREZGENE
Gene3D-CATH GPCR, family 2, extracellular hormone receptor domain UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_2 UniProtKB/TrEMBL
  GPCR_2-like_TM UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_GHRH_rcpt UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
KEGG Report hgl:101713164 UniProtKB/TrEMBL
NCBI Gene Ghrhr ENTREZGENE
PANTHER GROWTH HORMONE-RELEASING HORMONE RECEPTOR UniProtKB/TrEMBL
  PDF RECEPTOR-LIKE PROTEIN-RELATED UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
PRINTS GHRHRECEPTOR UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
SMART HormR UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
  Hormone receptor domain UniProtKB/TrEMBL
UniProt A0AAX6PQ11 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R8T5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R9D6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R9M4 ENTREZGENE, UniProtKB/TrEMBL