Orai3 (ORAI calcium release-activated calcium modulator 3) - Rat Genome Database

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Gene: Orai3 (ORAI calcium release-activated calcium modulator 3) Heterocephalus glaber
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Symbol: Orai3
Name: ORAI calcium release-activated calcium modulator 3
RGD ID: 18909988
Description: ENCODES a protein that exhibits calcium channel activity (inferred); store-operated calcium channel activity (inferred); INVOLVED IN store-operated calcium entry (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); dilated cardiomyopathy (ortholog); generalized epilepsy with febrile seizures plus 9 (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein orai-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478214,020,791 - 14,030,867 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478214,020,815 - 14,028,055 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Orai3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478214,020,791 - 14,030,867 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478214,020,815 - 14,028,055 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ORAI3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,949,068 - 30,954,938 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,949,068 - 30,956,461 (+)EnsemblGRCh38hg38GRCh38
GRCh371630,960,389 - 30,966,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,867,916 - 30,873,760 (+)NCBINCBI36Build 36hg18NCBI36
Celera1629,331,449 - 29,337,301 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,523,075 - 28,528,912 (+)NCBIHuRef
CHM1_11632,277,415 - 32,283,267 (+)NCBICHM1_1
T2T-CHM13v2.01631,336,531 - 31,342,399 (+)NCBIT2T-CHM13v2.0
Orai3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,368,987 - 127,374,322 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,368,987 - 127,374,322 (+)EnsemblGRCm39 Ensembl
GRCm387127,769,815 - 127,775,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,769,815 - 127,775,150 (+)EnsemblGRCm38mm10GRCm38
MGSCv377134,913,329 - 134,918,664 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,560,993 - 127,566,152 (+)NCBIMGSCv36mm8
Celera7127,605,006 - 127,610,345 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.73NCBI
Orai3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,811,671 - 191,816,530 (+)NCBIGRCr8
mRatBN7.21182,381,196 - 182,386,055 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,344,293 - 182,386,052 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,731,737 - 190,736,596 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,917,832 - 197,922,691 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,588,302 - 190,593,161 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,217,504 - 199,222,363 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,217,016 - 199,222,851 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,239,787 - 206,244,646 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,054,514 - 187,059,373 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,204,394 - 187,209,253 (+)NCBI
Celera1180,032,317 - 180,037,176 (+)NCBICelera
Cytogenetic Map1q37NCBI
Orai3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,799,738 - 7,806,590 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,799,738 - 7,806,590 (+)NCBIChiLan1.0ChiLan1.0
ORAI3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21834,154,764 - 34,160,896 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,956,223 - 38,962,309 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,014,018 - 24,019,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,314,878 - 31,321,562 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,314,922 - 31,323,320 (+)Ensemblpanpan1.1panPan2
ORAI3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,248,900 - 17,253,935 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,248,884 - 17,274,850 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,823,980 - 18,829,005 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,379,252 - 17,384,277 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,379,685 - 17,384,254 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,179,607 - 17,184,632 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,098,744 - 17,103,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,411,301 - 17,416,327 (-)NCBIUU_Cfam_GSD_1.0
Orai3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,234,885 - 125,240,976 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650113,332,757 - 13,339,324 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650113,332,859 - 13,338,838 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORAI3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,490,528 - 17,497,063 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,490,524 - 17,497,391 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,807,162 - 17,814,006 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ORAI3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,637,919 - 27,644,585 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,638,731 - 27,644,829 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,826,773 - 1,832,820 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000023909   ⟹   ENSHGLP00000023691
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478214,020,791 - 14,030,867 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000023910   ⟹   ENSHGLP00000023692
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478214,021,010 - 14,027,521 (+)Ensembl
RefSeq Acc Id: XM_004856199   ⟹   XP_004856256
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478214,020,815 - 14,028,055 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856256 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023691
RefSeq Acc Id: XP_004856256   ⟸   XM_004856199
- UniProtKB: G5BYD4 (UniProtKB/TrEMBL),   A0AAX6PQ50 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000023692   ⟸   ENSHGLT00000023910
Ensembl Acc Id: ENSHGLP00000023691   ⟸   ENSHGLT00000023909


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016905 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023909 ENTREZGENE
Gene3D-CATH Calcium release-activated calcium channel protein Orai UniProtKB/TrEMBL
InterPro CRAC_channel UniProtKB/TrEMBL
  Orai_sf UniProtKB/TrEMBL
NCBI Gene Orai3 ENTREZGENE
PANTHER CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN ORAI-3 UniProtKB/TrEMBL
Pfam Orai-1 UniProtKB/TrEMBL
UniProt A0AAX6PQ50 ENTREZGENE, UniProtKB/TrEMBL
  G5BYD4 ENTREZGENE, UniProtKB/TrEMBL