Lrp4 (LDL receptor related protein 4) - Rat Genome Database

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Gene: Lrp4 (LDL receptor related protein 4) Heterocephalus glaber
Analyze
Symbol: Lrp4
Name: LDL receptor related protein 4
RGD ID: 18907668
Description: ENCODES a protein that exhibits apolipoprotein binding (ortholog); coreceptor activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN amyloid-beta clearance by cellular catabolic process (ortholog); dendrite morphogenesis (ortholog); dorsal/ventral pattern formation (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Cenani-Lenz syndactyly syndrome (ortholog); congenital disorder of glycosylation type IIc (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN cell surface (ortholog); dendrite (ortholog); neuromuscular junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: low-density lipoprotein receptor-related protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247671,708,866 - 1,757,629 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lrp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247671,708,866 - 1,757,629 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LRP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381146,856,717 - 46,918,550 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1146,856,717 - 46,918,642 (-)EnsemblGRCh38hg38GRCh38
GRCh371146,878,268 - 46,940,101 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361146,834,994 - 46,896,652 (-)NCBINCBI36Build 36hg18NCBI36
Build 341146,834,994 - 46,874,397NCBI
Celera1147,024,050 - 47,085,802 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1146,584,196 - 46,645,441 (-)NCBIHuRef
CHM1_11146,876,690 - 46,938,585 (-)NCBICHM1_1
T2T-CHM13v2.01147,013,618 - 47,075,418 (-)NCBIT2T-CHM13v2.0
Lrp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39291,287,794 - 91,344,246 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl291,287,856 - 91,344,124 (+)EnsemblGRCm39 Ensembl
GRCm38291,457,456 - 91,513,901 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,457,511 - 91,513,779 (+)EnsemblGRCm38mm10GRCm38
MGSCv37291,297,688 - 91,354,058 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36291,258,540 - 91,314,618 (+)NCBIMGSCv36mm8
Celera292,845,990 - 92,902,350 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.63NCBI
Lrp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8397,885,373 - 97,939,366 (+)NCBIGRCr8
mRatBN7.2377,429,600 - 77,483,593 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl377,429,798 - 77,483,593 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,903,881 - 80,957,484 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0389,502,902 - 89,556,508 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0387,354,307 - 87,408,281 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0380,362,643 - 80,416,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,362,858 - 80,416,679 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0387,062,818 - 87,116,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,821,638 - 75,875,100 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,718,009 - 75,771,472 (+)NCBI
Celera376,634,746 - 76,688,537 (+)NCBICelera
Cytogenetic Map3q24NCBI
Lrp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554221,191,338 - 1,238,227 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554221,191,338 - 1,238,227 (+)NCBIChiLan1.0ChiLan1.0
LRP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,062,785 - 49,123,346 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,082,564 - 49,143,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01146,808,090 - 46,868,649 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,364,195 - 47,409,143 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,366,321 - 47,411,105 (-)Ensemblpanpan1.1panPan2
LRP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,616,683 - 42,667,297 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,616,426 - 42,665,794 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1841,344,660 - 41,396,887 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01843,271,285 - 43,323,513 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1843,271,155 - 43,323,246 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,756,909 - 42,808,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01842,312,112 - 42,364,153 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01843,041,646 - 43,093,851 (+)NCBIUU_Cfam_GSD_1.0
Lrp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494720,100,527 - 20,153,707 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365622,211,514 - 2,263,937 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365622,211,519 - 2,262,899 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl215,616,131 - 15,672,874 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1215,616,137 - 15,672,876 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,979,254 - 17,017,635 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,393,489 - 18,474,514 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,413,513 - 18,471,444 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038115,697,194 - 115,757,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004851895   ⟹   XP_004851952
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247671,728,272 - 1,757,629 (+)NCBI
RefSeq Acc Id: XM_004851897   ⟹   XP_004851954
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247671,708,866 - 1,733,283 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004851952 (Get FASTA)   NCBI Sequence Viewer  
  XP_004851954 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004851954   ⟸   XM_004851897
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004851952   ⟸   XM_004851895
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
NCBI Gene Lrp4 ENTREZGENE