Nr2f1 (nuclear receptor subfamily 2 group F member 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nr2f1 (nuclear receptor subfamily 2 group F member 1) Heterocephalus glaber
Analyze
Symbol: Nr2f1
Name: nuclear receptor subfamily 2 group F member 1
RGD ID: 18905036
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); retinoic acid-responsive element binding (ortholog); INVOLVED IN cerebral cortex regionalization (ortholog); forebrain development (ortholog); interneuron migration (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Bosch-Boonstra-Schaaf optic atrophy syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: COUP transcription factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474312,478,832 - 12,488,458 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474312,479,427 - 12,488,178 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nr2f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474312,478,832 - 12,488,458 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474312,479,427 - 12,488,178 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NR2F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38593,583,222 - 93,594,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl593,583,222 - 93,594,611 (+)EnsemblGRCh38hg38GRCh38
GRCh37592,918,928 - 92,930,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36592,944,799 - 92,955,544 (+)NCBINCBI36Build 36hg18NCBI36
Build 34592,944,798 - 92,955,540NCBI
Celera588,778,440 - 88,789,186 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef588,092,169 - 88,102,739 (+)NCBIHuRef
CHM1_1592,351,749 - 92,362,489 (+)NCBICHM1_1
T2T-CHM13v2.0594,067,283 - 94,078,673 (+)NCBIT2T-CHM13v2.0
Nr2f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391378,337,090 - 78,346,954 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1378,337,092 - 78,347,876 (-)EnsemblGRCm39 Ensembl
GRCm381378,188,971 - 78,198,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1378,188,973 - 78,199,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv371378,328,234 - 78,338,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361378,652,524 - 78,662,420 (-)NCBIMGSCv36mm8
Celera1380,475,542 - 80,485,460 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1341.38NCBI
Nr2f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr829,776,179 - 9,785,924 (-)NCBIGRCr8
mRatBN7.228,040,375 - 8,050,123 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl28,040,377 - 8,050,123 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx215,156,212 - 15,165,958 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0213,255,522 - 13,265,268 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.027,905,787 - 7,915,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.025,569,954 - 5,579,894 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl25,569,935 - 5,579,894 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.025,553,211 - 5,563,152 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.425,765,399 - 5,794,104 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.125,791,963 - 5,820,665 (-)NCBI
Celera24,489,100 - 4,498,590 (-)NCBICelera
Cytogenetic Map2q11NCBI
Nr2f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541818,614,995 - 18,624,584 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541818,615,548 - 18,622,984 (-)NCBIChiLan1.0ChiLan1.0
NR2F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2421,798,293 - 21,808,047 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1519,951,902 - 19,964,301 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0521,773,283 - 21,785,746 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1521,909,691 - 21,918,776 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl521,910,463 - 21,918,776 (-)Ensemblpanpan1.1panPan2
NR2F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1315,707,198 - 15,716,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl315,707,640 - 15,716,875 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha317,056,142 - 17,065,912 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0315,603,857 - 15,613,637 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl315,603,875 - 15,613,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1315,559,980 - 15,569,747 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0315,546,214 - 15,555,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0315,764,483 - 15,774,264 (-)NCBIUU_Cfam_GSD_1.0
Nr2f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213171,322,457 - 171,331,829 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365239,507,965 - 9,517,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365239,508,204 - 9,517,266 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR2F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2100,447,705 - 100,457,506 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12100,447,661 - 100,457,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22103,839,017 - 103,848,870 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR2F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1487,463,514 - 87,475,900 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl487,466,249 - 87,475,112 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604936,657,859 - 36,670,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013383   ⟹   ENSHGLP00000013244
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474312,478,832 - 12,488,458 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000013384   ⟹   ENSHGLP00000013245
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474312,480,495 - 12,488,458 (+)Ensembl
RefSeq Acc Id: XM_004841684   ⟹   XP_004841741
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474312,481,061 - 12,488,178 (+)NCBI
RefSeq Acc Id: XM_013071098   ⟹   XP_012926552
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474312,479,427 - 12,488,178 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004841741 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926552 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012926552   ⟸   XM_013071098
- Peptide Label: isoform X2
- UniProtKB: A0AAX6QSJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841741   ⟸   XM_004841684
- Peptide Label: isoform X1
- UniProtKB: A0AAX6P1X2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000013245   ⟸   ENSHGLT00000013384
Ensembl Acc Id: ENSHGLP00000013244   ⟸   ENSHGLT00000013383


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009458 Ensembl
Gene3D-CATH Retinoid X Receptor UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR2 UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
NCBI Gene Nr2f1 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
PRINTS COUPTNFACTOR UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
Superfamily-SCOP Nuclear receptor ligand-binding domain UniProtKB/TrEMBL
UniProt A0AAX6P1X2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QSJ9 ENTREZGENE, UniProtKB/TrEMBL