NR2F1 (nuclear receptor subfamily 2 group F member 1) - Rat Genome Database

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Gene: NR2F1 (nuclear receptor subfamily 2 group F member 1) Sus scrofa
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Symbol: NR2F1
Name: nuclear receptor subfamily 2 group F member 1
RGD ID: 14190379
Description: ENCODES a protein that exhibits retinoic acid-responsive element binding (ortholog); INVOLVED IN cerebral cortex regionalization (ortholog); forebrain development (ortholog); negative regulation of neuron projection development (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Bosch-Boonstra-Schaaf optic atrophy syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH arotinoid acid; deoxynivalenol; zearalenone
Type: protein-coding
RefSeq Status: MODEL
Previously known as: COUP transcription factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2100,447,705 - 100,457,506 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12100,447,661 - 100,457,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22103,839,017 - 103,848,870 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NR2F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2100,447,705 - 100,457,506 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12100,447,661 - 100,457,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22103,839,017 - 103,848,870 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR2F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38593,583,222 - 93,594,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl593,583,222 - 93,594,611 (+)Ensemblhg38GRCh38
GRCh37592,918,928 - 92,930,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36592,944,799 - 92,955,544 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34592,944,798 - 92,955,540NCBI
Celera588,778,440 - 88,789,186 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef588,092,169 - 88,102,739 (+)NCBIHuRef
CHM1_1592,351,749 - 92,362,489 (+)NCBICHM1_1
T2T-CHM13v2.0594,067,283 - 94,078,673 (+)NCBIT2T-CHM13v2.0
Nr2f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391378,337,090 - 78,346,954 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1378,337,092 - 78,347,876 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381378,188,971 - 78,198,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1378,188,973 - 78,199,757 (-)Ensemblmm10GRCm38
MGSCv371378,328,234 - 78,338,243 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361378,652,524 - 78,662,420 (-)NCBIMGSCv36mm8
Celera1380,475,542 - 80,485,460 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1341.38NCBI
Nr2f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr829,776,179 - 9,785,924 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl29,776,179 - 9,785,924 (-)EnsemblGRCr8
mRatBN7.228,040,375 - 8,050,123 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl28,040,377 - 8,050,123 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx215,156,212 - 15,165,958 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0213,255,522 - 13,265,268 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.027,905,787 - 7,915,533 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.025,569,954 - 5,579,894 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl25,569,935 - 5,579,894 (-)Ensemblrn6Rnor6.0
Rnor_5.025,553,211 - 5,563,152 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.425,765,399 - 5,794,104 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera24,489,100 - 4,498,590 (-)NCBICelera
RGSC_v3.125,791,963 - 5,820,665 (-)NCBI
Cytogenetic Map2q11NCBI
Nr2f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541818,614,995 - 18,624,584 (-)Ensembl
ChiLan1.0NW_00495541818,615,548 - 18,622,984 (-)NCBIChiLan1.0ChiLan1.0
NR2F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2421,798,293 - 21,808,047 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1519,951,902 - 19,964,301 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0521,773,283 - 21,785,746 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1521,909,691 - 21,918,776 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl521,910,463 - 21,918,776 (-)EnsemblpanPan2panpan1.1
NR2F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1315,707,198 - 15,716,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl315,707,640 - 15,716,875 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha317,056,142 - 17,065,912 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0315,603,857 - 15,613,637 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl315,603,875 - 15,613,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1315,559,980 - 15,569,747 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0315,546,214 - 15,555,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0315,764,483 - 15,774,264 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nr2f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213171,322,457 - 171,331,829 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365239,507,965 - 9,517,272 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365239,508,204 - 9,517,266 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR2F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1487,463,514 - 87,475,900 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl487,466,249 - 87,475,112 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604936,657,859 - 36,670,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr2f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474312,478,832 - 12,488,458 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474312,479,427 - 12,488,178 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nr2f1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13218,424,902 - 218,434,065 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in NR2F1
119 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000015465   ⟹   ENSSSCP00000015055
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2100,447,705 - 100,457,506 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000037613   ⟹   ENSSSCP00000047766
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2100,447,803 - 100,457,506 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000065997   ⟹   ENSSSCP00000036185
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2100,448,748 - 100,456,987 (+)Ensembl
RefSeq Acc Id: XM_003354213   ⟹   XP_003354261
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12100,447,661 - 100,456,987 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003354214   ⟹   XP_003354262
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12100,448,548 - 100,457,510 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003354261   ⟸   XM_003354213
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TCJ9 (UniProtKB/TrEMBL),   F1RNX7 (UniProtKB/TrEMBL),   A0A8D0P7V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003354262   ⟸   XM_003354214
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TGR9 (UniProtKB/TrEMBL),   A0A8D1F517 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000015055   ⟸   ENSSSCT00000015465
Ensembl Acc Id: ENSSSCP00000036185   ⟸   ENSSSCT00000065997
Ensembl Acc Id: ENSSSCP00000047766   ⟸   ENSSSCT00000037613
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014157 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015055569 UniProtKB/TrEMBL
  ENSSSCG00025052437 UniProtKB/TrEMBL
  ENSSSCG00030016506 UniProtKB/TrEMBL
  ENSSSCG00030037214 UniProtKB/TrEMBL
  ENSSSCG00035071188 UniProtKB/TrEMBL
  ENSSSCG00040020750 UniProtKB/TrEMBL
  ENSSSCG00040053726 UniProtKB/TrEMBL
  ENSSSCG00045027580 UniProtKB/TrEMBL
  ENSSSCG00045027982 UniProtKB/TrEMBL
  ENSSSCG00050019418 UniProtKB/TrEMBL
  ENSSSCG00050023599 UniProtKB/TrEMBL
  ENSSSCG00055012879 UniProtKB/TrEMBL
  ENSSSCG00060000889 UniProtKB/TrEMBL
  ENSSSCG00060032083 UniProtKB/TrEMBL
  ENSSSCG00065026327 UniProtKB/TrEMBL
  ENSSSCG00070008710 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015465 ENTREZGENE
  ENSSSCT00000015465.5 UniProtKB/TrEMBL
  ENSSSCT00000037613.3 UniProtKB/TrEMBL
  ENSSSCT00015074070.1 UniProtKB/TrEMBL
  ENSSSCT00015074116.1 UniProtKB/TrEMBL
  ENSSSCT00025071806.1 UniProtKB/TrEMBL
  ENSSSCT00025071902.1 UniProtKB/TrEMBL
  ENSSSCT00025071987.1 UniProtKB/TrEMBL
  ENSSSCT00030022887.1 UniProtKB/TrEMBL
  ENSSSCT00030051810.1 UniProtKB/TrEMBL
  ENSSSCT00030051853.1 UniProtKB/TrEMBL
  ENSSSCT00030051876.1 UniProtKB/TrEMBL
  ENSSSCT00035096224.1 UniProtKB/TrEMBL
  ENSSSCT00035096256.1 UniProtKB/TrEMBL
  ENSSSCT00035096274.1 UniProtKB/TrEMBL
  ENSSSCT00040028074.1 UniProtKB/TrEMBL
  ENSSSCT00040028131.1 UniProtKB/TrEMBL
  ENSSSCT00040028139.1 UniProtKB/TrEMBL
  ENSSSCT00040072764.1 UniProtKB/TrEMBL
  ENSSSCT00045047202.1 UniProtKB/TrEMBL
  ENSSSCT00045047901.1 UniProtKB/TrEMBL
  ENSSSCT00045047980.1 UniProtKB/TrEMBL
  ENSSSCT00045048070.1 UniProtKB/TrEMBL
  ENSSSCT00050026238.1 UniProtKB/TrEMBL
  ENSSSCT00050026258.1 UniProtKB/TrEMBL
  ENSSSCT00050026269.1 UniProtKB/TrEMBL
  ENSSSCT00050031878.1 UniProtKB/TrEMBL
  ENSSSCT00055025496.1 UniProtKB/TrEMBL
  ENSSSCT00055025553.1 UniProtKB/TrEMBL
  ENSSSCT00055025591.1 UniProtKB/TrEMBL
  ENSSSCT00060001035.1 UniProtKB/TrEMBL
  ENSSSCT00060043485.1 UniProtKB/TrEMBL
  ENSSSCT00060043493.1 UniProtKB/TrEMBL
  ENSSSCT00060043502.1 UniProtKB/TrEMBL
  ENSSSCT00065035369.1 UniProtKB/TrEMBL
  ENSSSCT00065035372.1 UniProtKB/TrEMBL
  ENSSSCT00065035373.1 UniProtKB/TrEMBL
  ENSSSCT00070016891.1 UniProtKB/TrEMBL
  ENSSSCT00070016906.1 UniProtKB/TrEMBL
  ENSSSCT00070016916.1 UniProtKB/TrEMBL
  ENSSSCT00070016921.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro NHR_like_dom_sf UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR2 UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report ssc:100621341 UniProtKB/TrEMBL
NCBI Gene NR2F1 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS COUPTNFACTOR UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt A0A287AV73_PIG UniProtKB/TrEMBL
  A0A4X1TCJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TEC4_PIG UniProtKB/TrEMBL
  A0A4X1TFX9_PIG UniProtKB/TrEMBL
  A0A4X1TGR9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0P7V3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1F517 ENTREZGENE, UniProtKB/TrEMBL
  F1RNX7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90880 ENTREZGENE