TMEM126A (transmembrane protein 126A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: TMEM126A (transmembrane protein 126A) Chlorocebus sabaeus
Analyze
Symbol: TMEM126A
Name: transmembrane protein 126A
RGD ID: 18773472
Description: INVOLVED IN toll-like receptor 4 signaling pathway (ortholog); ASSOCIATED WITH exudative vitreoretinopathy 1 (ortholog); Hereditary Optic Atrophies (ortholog); intellectual disability (ortholog); FOUND IN mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1176,888,688 - 76,897,883 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl176,888,734 - 76,897,841 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604348,824,623 - 48,833,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TMEM126A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1176,888,688 - 76,897,883 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl176,888,734 - 76,897,841 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604348,824,623 - 48,833,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TMEM126A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,647,967 - 85,656,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,647,967 - 85,656,547 (+)EnsemblGRCh38hg38GRCh38
GRCh371185,359,011 - 85,367,586 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,036,693 - 85,045,235 (+)NCBINCBI36Build 36hg18NCBI36
Celera1182,668,277 - 82,676,912 (+)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1181,656,256 - 81,664,891 (+)NCBIHuRef
CHM1_11185,243,754 - 85,252,388 (+)NCBICHM1_1
T2T-CHM13v2.01185,584,644 - 85,593,220 (+)NCBIT2T-CHM13v2.0
Tmem126a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39790,099,908 - 90,106,411 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl790,099,908 - 90,106,437 (-)EnsemblGRCm39 Ensembl
GRCm38790,450,700 - 90,457,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl790,450,700 - 90,457,229 (-)EnsemblGRCm38mm10GRCm38
MGSCv37797,599,222 - 97,605,718 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36790,325,904 - 90,332,400 (-)NCBIMGSCv36mm8
Celera787,778,196 - 87,784,676 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map750.59NCBI
Tmem126a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,837,015 - 153,843,192 (-)NCBIGRCr8
mRatBN7.21144,424,481 - 144,430,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1144,422,703 - 144,430,628 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1152,347,274 - 152,353,446 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01159,528,451 - 159,534,610 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01152,402,370 - 152,408,529 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01156,283,105 - 156,291,057 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1156,283,128 - 156,291,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,529,113 - 162,537,179 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41147,129,330 - 147,137,259 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11147,207,735 - 147,215,665 (-)NCBI
Celera1142,643,098 - 142,651,027 (-)NCBICelera
Cytogenetic Map1q32NCBI
Tmem126a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554147,216,286 - 7,224,475 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554147,214,408 - 7,224,499 (-)NCBIChiLan1.0ChiLan1.0
TMEM126A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2986,567,317 - 86,579,574 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11187,620,767 - 87,630,548 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,703,855 - 80,712,459 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,312,434 - 84,321,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,312,434 - 84,321,037 (+)Ensemblpanpan1.1panPan2
TMEM126A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12113,787,074 - 13,795,779 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2113,787,123 - 13,795,739 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2113,653,725 - 13,662,471 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02113,967,872 - 13,976,597 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2113,967,464 - 13,976,562 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12113,756,370 - 13,765,102 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02113,828,697 - 13,837,423 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02113,881,469 - 13,890,217 (-)NCBIUU_Cfam_GSD_1.0
Tmem126a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494771,938,905 - 71,945,739 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493649813,538,565 - 13,545,338 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM126A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl919,576,295 - 19,585,277 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1919,576,241 - 19,585,869 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2921,846,389 - 21,855,417 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tmem126a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248454,264,497 - 4,272,973 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008020337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000001713   ⟹   ENSCSAP00000000054
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl176,888,734 - 76,897,841 (+)Ensembl
RefSeq Acc Id: XM_008020337   ⟹   XP_008018528
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,888,688 - 76,897,883 (+)NCBI
Vero_WHO_p1.0NW_02366604348,824,623 - 48,833,726 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008018528 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000054
  ENSCSAP00000000054.1
RefSeq Acc Id: XP_008018528   ⟸   XM_008020337
- UniProtKB: A0A0D9QUL5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000054   ⟸   ENSCSAT00000001713


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003683 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001713.1 UniProtKB/TrEMBL
InterPro TMEM126 UniProtKB/TrEMBL
KEGG Report csab:103248135 UniProtKB/TrEMBL
NCBI Gene TMEM126A ENTREZGENE
PANTHER PTHR16296 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 126A UniProtKB/TrEMBL
Pfam TMEM126 UniProtKB/TrEMBL
UniProt A0A0D9QUL5 ENTREZGENE, UniProtKB/TrEMBL