STX1B (syntaxin 1B) - Rat Genome Database

Name: STX1B
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: STX1B (syntaxin 1B) Chlorocebus sabaeus

Analyze

Symbol:

STX1B

Name:

syntaxin 1B

RGD ID:

18654589

Description:

ENCODES a protein that exhibits protein domain specific binding (ortholog); protein kinase binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN calcium ion-regulated exocytosis of neurotransmitter (ortholog); exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); negative regulation of synaptic vesicle recycling (ortholog); ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); Duchenne muscular dystrophy (ortholog); epilepsy (ortholog); FOUND IN axon (ortholog); centrosome (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

syntaxin-1B

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	STX1B (syntaxin 1B)	NCBI	Ortholog
Mus musculus (house mouse):	Stx1b (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Stx1b (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Stx1b (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	STX1B (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	STX1B (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Stx1b (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	STX1B (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Stx1b (syntaxin 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,683,526 - 27,702,032 (-)	NCBI
ChlSab1.1 Ensembl	5	27,684,082 - 27,694,814 (-)	Ensembl

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

branched-chain keto acid dehydrogenase kinase deficiency (ISO)

Duchenne muscular dystrophy (ISO)

epilepsy (ISO)

Febrile Seizures (ISO)

generalized epilepsy with febrile seizures plus 9 (ISO)

genetic disease (ISO)

visual epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium ion-regulated exocytosis of neurotransmitter (ISO)

exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ISO)

negative regulation of synaptic vesicle recycling (ISO)

positive regulation of excitatory postsynaptic potential (ISO)

positive regulation of neurotransmitter secretion (ISO)

positive regulation of spontaneous neurotransmitter secretion (ISO)

protein localization to membrane (ISO)

protein transport (ISO)

regulation of exocytosis (ISO)

regulation of gene expression (ISO)

regulation of synaptic vesicle priming (ISO)

spontaneous neurotransmitter secretion (ISO)

synaptic vesicle docking (ISO)

synaptic vesicle exocytosis (ISO)

synaptic vesicle fusion to presynaptic active zone membrane (ISO)

vesicle docking involved in exocytosis (ISO)

vesicle-mediated transport (ISO)

Cellular Component

axon (ISO)

centrosome (ISO)

cytoplasm (ISO)

membrane (ISO)

neuromuscular junction (ISO)

nuclear lamina (ISO)

nucleoplasm (ISO)

nucleus (ISO)

plasma membrane (ISO)

presynapse (ISO)

presynaptic active zone membrane (ISO)

presynaptic membrane (ISO)

Molecular Function

protein binding (ISO)

protein domain specific binding (ISO)

protein kinase binding (ISO)

signaling receptor binding (ISO)

References

Genomics

Comparative Map Data

STX1B
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,683,526 - 27,702,032 (-)	NCBI
ChlSab1.1 Ensembl	5	27,684,082 - 27,694,814 (-)	Ensembl

STX1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	16	30,989,256 - 31,010,638 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	16	30,989,256 - 31,010,638 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	16	31,000,577 - 31,021,829 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	30,910,869 - 30,929,276 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	16	30,910,868 - 30,929,276	NCBI
Celera	16	29,275,546 - 29,296,879 (+)	NCBI
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	28,563,033 - 28,574,857 (-)	NCBI		HuRef
CHM1_1	16	32,317,577 - 32,338,959 (-)	NCBI		CHM1_1

Stx1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	127,403,072 - 127,423,703 (-)	NCBI	GRCm39		mm39
GRCm38	7	127,803,900 - 127,824,531 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,803,900 - 127,824,549 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	134,950,358 - 134,968,045 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	127,598,364 - 127,615,438 (-)	NCBI			mm8
Celera	7	127,641,815 - 127,659,486 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

Stx1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	199,251,842 - 199,270,465 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	199,251,844 - 199,270,627 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	206,276,724 - 206,292,888 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	187,092,014 - 187,108,481 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	187,239,062 - 187,258,524 (-)	NCBI
Celera	1	180,069,042 - 180,085,214 (-)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

Stx1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	7,838,684 - 7,857,700 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	7,838,684 - 7,857,700 (-)	NCBI	ChiLan1.0	ChiLan1.0

STX1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	16	31,356,907 - 31,378,864 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	31,356,907 - 31,378,870 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	16	23,956,426 - 23,979,646 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

STX1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	6	17,210,433 - 17,241,363 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	6	17,209,972 - 17,219,903 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Stx1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936501	13,370,678 - 13,378,933 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STX1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	17,439,581 - 17,459,516 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	17,439,563 - 17,459,517 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	17,848,121 - 17,856,072 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Stx1b
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624782	14,054,762 - 14,073,890 (-)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	18		58
Low	18	16	2
Below cutoff		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007990460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCSAT00000003782 ⟹ ENSCSAP00000002058

RefSeq Status:

Type:

CODING

Position:

Vervet Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	27,684,082 - 27,694,814 (-)	Ensembl

RefSeq Acc Id:

XM_007990460 ⟹ XP_007988651

RefSeq Status:

Type:

CODING

Position:

Vervet Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	27,683,526 - 27,702,032 (-)	NCBI

Sequence:

show sequence

CGAGGCGGGAGACCGGGAGCAGCAACAGAGGCAGGAGGACGAGGAGGAGGAGGAGGAGCCGTCG
CAGGATGAAGGATCGGACTCAGGAGCTGCGGAGTGCGAAAGACAGTGATGATGAAGAGGAGGTG
GTCCACGTGGATCGGGACCACTTCATGGATGAGTTCTTTGAACAGGTGGAAGAGATCCGGGGCT
GCATTGAGAAACTGTCGGAGGATGTGGAGCAGGTGAAAAAACAGCATAGCGCCATCCTGGCTGC
CCCCAACCCAGATGAGAAGACCAAACAGGAGCTGGAGGACCTCACTGCAGACATCAAGAAGACG
GCCAACAAGGTTCGGTCCAAATTGAAAGCGATCGAGCAAAGCATTGAACAGGAGGAGGGGCTCA
ACCGTTCCTCCGCGGACCTGCGCATCCGCAAGACCCAGCACTCCACACTGTCCCGGAAGTTCGT
GGAGGTAATGACCGAATATAACGCGACCCAGTCCAAGTACCGGGACCGCTGCAAGGACCGGATC
CAGCGGCAACTGGAGATCACTGGAAGGACCACCACCAACGAAGAACTGGAAGACATGCTGGAGA
GCGGGAAGCTGGCTATCTTCACAGATGACATCAAAATGGACTCACAGATGACGAAGCAGGCGCT
GAATGAGATCGAGACAAGGCACAATGAGATCATCAAGCTGGAAACCAGCATCCGTGAGCTGCAC
GACATGTTTGTGGACATGGCCATGCTTGTAGAGAGCCAGGGAGAGATGATTGACCGCATCGAGT
ACAACGTGGAACATTCTGTAGACTACGTGGAGCGAGCTGTGTCTGACACCAAGAAAGCAGTGAA
ATATCAGAGCAAGGCCCGGAGGAAGAAAATCATGATCATCATTTGCTGTGTGGTGCTGGGGGTG
GTCTTGGCGTCATCCATTGGGGGGACGCTGGGCTTGTAGGCCCCCCACCCTTCTCTCTCCCAGA
CCCCTCCCCCACCACATCGGGAGCAATACCCCCACCACCCCTTTCACTCCATCCCCTGCTCCAG
GCTCACCCCCAAAACAGACCCAGGCAGCCCCACCCCTCCTCCACCCCCATGGCAGACCCTGGTG
TCCCTGGACCTTACCCGGCCATGGACCTCCCTGCCCCCGCACGTAGATCGCAGCAGGCGTGATT
ACACATGCACACCAACATGCATGCCGCCGGCACATGCTCAAGACGTGTGGACACCCCAGCGTGT
GTGTGCGTGTGATGTGTGTGATGCACCAGAGCACCCCCCTGACCCCGCCTCGGGTATGTGTGCG
TGGTCTGAGCTTCCCCCTTCACCGGGGCTGTTGTGTAGACTGCAGCCGAGTGTAACACAGCTGC
CCACCACGCCCCTCTCTGTCCTCTGTGAACGGTGTGTGTGTGTGAGTGAGACCACAGATCTGTG
GACACGCCATTCGTGTACGTGGAATTTTGTGTTTGAGTGTTTGAACCTAATGCAACAGCAACAA
AGCCACTGATACC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007988651	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_007988651 ⟸ XM_007990460

RefSeq Acc Id:

ENSCSAP00000002058 ⟸ ENSCSAT00000003782

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005756	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCSAP00000002058	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003782	UniProtKB/TrEMBL
InterPro	SNARE	UniProtKB/TrEMBL
	STX1	UniProtKB/TrEMBL
	Syntaxin/epimorphin_CS	UniProtKB/TrEMBL
	Syntaxin_N	UniProtKB/TrEMBL
	T_SNARE_dom	UniProtKB/TrEMBL
NCBI Gene	STX1B	ENTREZGENE
PANTHER	PTHR19957:SF84	UniProtKB/TrEMBL
Pfam	SNARE	UniProtKB/TrEMBL
	Syntaxin	UniProtKB/TrEMBL
PROSITE	SYNTAXIN	UniProtKB/TrEMBL
	T_SNARE	UniProtKB/TrEMBL
SMART	SynN	UniProtKB/TrEMBL
	t_SNARE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47661	UniProtKB/TrEMBL
UniProt	A0A0D9R0B9_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM