NOL3 (nucleolar protein 3) - Rat Genome Database

Name: NOL3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: NOL3 (nucleolar protein 3) Chlorocebus sabaeus

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Symbol:

NOL3

Name:

nucleolar protein 3

RGD ID:

18618425

Description:

ENCODES a protein that exhibits calcium ion binding (ortholog); caspase binding (ortholog); cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle cell apoptotic process (ortholog); cellular response to hydrogen peroxide (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); cataract 5 multiple types (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleolus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NOL3 (nucleolar protein 3)	NCBI	Ortholog
Mus musculus (house mouse):	Nol3 (nucleolar protein 3 (apoptosis repressor with CARD domain))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nol3 (nucleolar protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nol3 (nucleolar protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NOL3 (nucleolar protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nol3 (nucleolar protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	60,281,492 - 60,286,865 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,039,019 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

cataract 5 multiple types (ISO)

Chromosome 16q12 Duplication Syndrome (ISO)

COVID-19 (ISO)

Familial Myoclonus 1 (ISO)

mitochondrial metabolism disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood vessel remodeling (ISO)

cardiac muscle cell apoptotic process (ISO)

cellular response to hydrogen peroxide (ISO)

cellular response to hypoxia (ISO)

inhibition of cysteine-type endopeptidase activity (ISO)

intrinsic apoptotic signaling pathway (ISO)

mRNA splice site recognition (ISO)

myoblast differentiation (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of cardiac muscle cell apoptotic process (ISO)

negative regulation of cysteine-type endopeptidase activity (ISO)

negative regulation of cytosolic calcium ion concentration (ISO)

negative regulation of death-inducing signaling complex assembly (ISO)

negative regulation of extrinsic apoptotic signaling pathway (ISO)

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ISO)

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (ISO)

negative regulation of intrinsic apoptotic signaling pathway (ISO)

negative regulation of mitochondrial calcium ion concentration (ISO)

negative regulation of mitochondrial membrane permeability involved in apoptotic process (ISO)

negative regulation of muscle atrophy (ISO)

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (ISO)

negative regulation of programmed necrotic cell death (ISO)

negative regulation of protein targeting to mitochondrion (ISO)

negative regulation of release of cytochrome c from mitochondria (ISO)

negative regulation of striated muscle cell apoptotic process (ISO)

negative regulation of tumor necrosis factor-mediated signaling pathway (ISO)

protein complex oligomerization (ISO)

regulation of gene expression (ISO)

regulation of non-canonical NF-kappaB signal transduction (ISO)

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (ISO)

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (ISO)

response to hypoxia (ISO)

response to injury involved in regulation of muscle adaptation (ISO)

response to ischemia (ISO)

smooth muscle cell proliferation (ISO)

Cellular Component

cytoplasm (ISO)

mitochondrion (ISO)

nucleolus (ISO)

sarcoplasm (ISO)

sarcoplasmic reticulum (ISO)

Molecular Function

calcium ion binding (ISO)

caspase binding (ISO)

cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ISO)

death effector domain binding (ISO)

death receptor binding (ISO)

identical protein binding (ISO)

kinase binding (ISO)

phosphatase binding (ISO)

protein binding (ISO)

signaling receptor binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

NOL3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	60,281,492 - 60,286,865 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,039,019 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

NOL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	67,170,538 - 67,175,737 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	67,170,154 - 67,175,737 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	67,204,441 - 67,209,640 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	65,765,371 - 65,767,127 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	65,765,370 - 65,767,125	NCBI
Celera	16	51,712,649 - 51,717,887 (+)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	53,077,589 - 53,082,828 (+)	NCBI		HuRef
CHM1_1	16	68,611,732 - 68,616,967 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	72,964,831 - 72,970,031 (+)	NCBI		T2T-CHM13v2.0

Nol3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	106,002,777 - 106,008,571 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	106,002,772 - 106,008,571 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	105,276,145 - 105,281,939 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	105,276,140 - 105,281,939 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	107,800,347 - 107,805,839 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	108,165,576 - 108,171,068 (+)	NCBI		MGSCv36	mm8
Celera	8	109,499,596 - 109,505,088 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.04	NCBI

Nol3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,066,493 - 50,068,175 (+)	NCBI		GRCr8
mRatBN7.2	19	33,154,061 - 33,158,250 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,154,062 - 33,158,250 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	39,972,172 - 39,973,839 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	40,625,491 - 40,627,158 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	42,914,430 - 42,916,067 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	37,232,567 - 37,236,668 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,235,001 - 37,236,649 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	48,098,203 - 48,102,390 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	35,094,345 - 35,096,012 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	35,099,225 - 35,100,893 (+)	NCBI
Celera	19	32,585,344 - 32,587,011 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

Nol3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	9,443,090 - 9,447,095 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955484	9,443,090 - 9,447,142 (-)	NCBI	ChiLan1.0	ChiLan1.0

NOL3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	76,700,244 - 76,705,501 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	82,612,801 - 82,618,419 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	47,516,156 - 47,521,441 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	66,904,738 - 66,909,956 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	66,904,738 - 66,909,956 (+)	Ensembl	panpan1.1		panPan2

Nol3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	41,940,899 - 41,944,816 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	17,644,653 - 17,648,211 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	17,644,299 - 17,648,213 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007994028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007994029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007994030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007994031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007994029 ⟹ XP_007992220

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	60,281,492 - 60,286,168 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,038,410 (-)	NCBI

Sequence:

show sequence

CAGCGACCCGTCACCGGCTGCGGCGCTCGGGGTGAGGTCTGTGGGCCCCGCCCTGCCGCAGGAC
TCTCAAGCTCTGGGACTGGGCCTGACAATGGGCAACGCGCAGGAGCGGCCGTCGGAGACTATAG
ACCGCGAGAGGAAACGCCTGGTCGAGACATTGCAGGCGGACTCGGGGCTGCTGCTGGACGCGCT
GTTGGCGCGAGGCGTGCTCACCGGGCCAGAGTACGAGGCATTGGATGCACTGCCTGATGCCGAG
CGGAGGGTGCGCCGCCTACTGCTGCTGGTGCAGGGCAAGGGCGAGGCCGCCTGCCAGGAGCTGC
TGCGCTGTGCCCAGCGTACCGCAGGCGCGCCTGACCCCGCCTGGGACTGGCAGCACGTGGGTCC
GGGTTACCGGGACCGCAGCTATGACCCTCCATGCCCAGGCCACTGGACGCCGGAGGCACCCGGC
TCGGGGACCACATGCCCCGGGTTGCCCAGAGCTTCAGACACCGACGAGGCCGGGGGCCTCGAGG
GCTGCGAGGCGGTGCAATCCGGGACCCCAGAGGAACCAGAGCCAGAGCTGGAAGCAGAGGCCTC
TGAAGAGGCTGAACTGGAGCCAGAGCCAGAGCTGGAACCCGAACCTGAAGCAGAACCAGAGCCG
GAACTGGAGCCAGAACCAGACCCAGAGCCTGAGCCCGACTTCGAGGAAGGGGATGAGTCGGAAG
ATTCCTGAAGGCCAGAACTCTGACTGGCCATGCCCCGCCCATGCTGGATAGGACCTGGGATGCT
GCTGGAGCCGAATCGGATGCCACCAAGGCTCAGTCCAGCCCAGTACTTCTGGAAGTGAATAAAC
TCCGGAGGGTCCACCGGGACCTGGGCTCTCTCCA

hide sequence

RefSeq Acc Id:

XM_007994030 ⟹ XP_007992221

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	60,281,492 - 60,286,079 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,038,383 (-)	NCBI

Sequence:

show sequence

TCTGGGAGGCCTGACAATGGGCAACGCGCAGGAGCGGCCGTCGGAGACTATAGACCGCGAGAGG
AAACGCCTGGTCGAGACATTGCAGGCGGACTCGGGGCTGCTGCTGGACGCGCTGTTGGCGCGAG
GCGTGCTCACCGGGCCAGAGTACGAGGCATTGGATGCACTGCCTGATGCCGAGCGGAGGGTGCG
CCGCCTACTGCTGCTGGTGCAGGGCAAGGGCGAGGCCGCCTGCCAGGAGCTGCTGCGCTGTGCC
CAGCGTACCGCAGGCGCGCCTGACCCCGCCTGGGACTGGCAGCACGTGGGTCCGGGTTACCGGG
ACCGCAGCTATGACCCTCCATGCCCAGGCCACTGGACGCCGGAGGCACCCGGCTCGGGGACCAC
ATGCCCCGGGTTGCCCAGAGCTTCAGACACCGACGAGGCCGGGGGCCTCGAGGGCTGCGAGGCG
GTGCAATCCGGGACCCCAGAGGAACCAGAGCCAGAGCTGGAAGCAGAGGCCTCTGAAGAGGCTG
AACTGGAGCCAGAGCCAGAGCTGGAACCCGAACCTGAAGCAGAACCAGAGCCGGAACTGGAGCC
AGAACCAGACCCAGAGCCTGAGCCCGACTTCGAGGAAGGGGATGAGTCGGAAGATTCCTGAAGG
CCAGAACTCTGACTGGCCATGCCCCGCCCATGCTGGATAGGACCTGGGATGCTGCTGGAGCCGA
ATCGGATGCCACCAAGGCTCAGTCCAGCCCAGTACTTCTGGAAGTGAATAAACTCCGGAGGGTC
CACCGGGACCTGGGCTCTCTCCA

hide sequence

RefSeq Acc Id:

XM_038008368 ⟹ XP_037864296

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,039,019 (-)	NCBI

RefSeq Acc Id:

XM_038008369 ⟹ XP_037864297

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,038,217 (-)	NCBI

RefSeq Acc Id:

XM_038008370 ⟹ XP_037864298

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,038,355 (-)	NCBI

RefSeq Acc Id:

XM_038008371 ⟹ XP_037864299

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	23,033,169 - 23,038,217 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007992220	(Get FASTA)	NCBI Sequence Viewer
	XP_007992221	(Get FASTA)	NCBI Sequence Viewer
	XP_037864296	(Get FASTA)	NCBI Sequence Viewer
	XP_037864297	(Get FASTA)	NCBI Sequence Viewer
	XP_037864298	(Get FASTA)	NCBI Sequence Viewer
	XP_037864299	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_007992220 ⟸ XM_007994029
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_007992221 ⟸ XM_007994030
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_037864296 ⟸ XM_038008368
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_037864298 ⟸ XM_038008370
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_037864299 ⟸ XM_038008371
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_037864297 ⟸ XM_038008369
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	NOL3	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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