TRPM7 (transient receptor potential cation channel subfamily M member 7) - Rat Genome Database

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Gene: TRPM7 (transient receptor potential cation channel subfamily M member 7) Chlorocebus sabaeus
Analyze
Symbol: TRPM7
Name: transient receptor potential cation channel subfamily M member 7
RGD ID: 18525752
Description: ENCODES a protein that exhibits calcium channel activity (ortholog); monoatomic cation channel activity (ortholog); protein kinase activity (ortholog); INVOLVED IN actomyosin structure organization (ortholog); calcium ion transport (ortholog); calcium-dependent cell-matrix adhesion (ortholog); ASSOCIATED WITH adenoma (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 (ortholog); FOUND IN neuronal cell body (ortholog); synaptic vesicle membrane (ortholog); varicosity (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,644,637 - 32,772,753 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2632,669,187 - 32,771,378 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048108,383,877 - 108,505,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRPM7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,644,637 - 32,772,753 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2632,669,187 - 32,771,378 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048108,383,877 - 108,505,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRPM7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381550,557,158 - 50,686,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1550,552,473 - 50,686,797 (-)EnsemblGRCh38hg38GRCh38
GRCh371550,849,355 - 50,978,994 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361548,639,782 - 48,766,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 341548,639,782 - 48,766,260NCBI
Celera1527,741,918 - 27,871,940 (-)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1527,680,107 - 27,809,975 (-)NCBIHuRef
CHM1_11550,967,308 - 51,096,974 (-)NCBICHM1_1
T2T-CHM13v2.01548,365,238 - 48,493,853 (-)NCBIT2T-CHM13v2.0
Trpm7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392126,633,478 - 126,718,181 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2126,633,485 - 126,718,150 (-)EnsemblGRCm39 Ensembl
GRCm382126,791,558 - 126,876,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2126,791,565 - 126,876,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv372126,617,294 - 126,701,997 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362126,483,006 - 126,567,652 (-)NCBIMGSCv36mm8
Celera2128,031,446 - 128,117,211 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.76NCBI
Trpm7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,499,617 - 134,588,113 (-)NCBIGRCr8
mRatBN7.23114,046,258 - 114,134,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,046,258 - 114,135,190 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3117,929,825 - 118,020,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,525,352 - 126,616,298 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,185,735 - 124,276,677 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,258,189 - 119,347,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,259,467 - 119,330,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03125,783,080 - 125,871,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,320,799 - 114,410,498 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13114,227,081 - 114,234,961 (-)NCBI
Celera3112,886,549 - 112,974,913 (-)NCBICelera
Cytogenetic Map3q36NCBI
Trpm7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554093,691,039 - 3,785,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554093,690,722 - 3,787,139 (+)NCBIChiLan1.0ChiLan1.0
TRPM7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21639,808,442 - 39,937,735 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11543,988,947 - 44,115,197 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01529,513,220 - 29,639,506 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11547,852,859 - 47,977,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1547,853,187 - 47,977,451 (-)Ensemblpanpan1.1panPan2
TRPM7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13016,465,546 - 16,579,874 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3016,466,234 - 16,579,594 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3016,391,627 - 16,505,679 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03016,609,528 - 16,723,877 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3016,609,860 - 16,723,804 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13016,531,991 - 16,646,305 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03016,650,052 - 16,764,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03016,756,456 - 16,870,962 (-)NCBIUU_Cfam_GSD_1.0
Trpm7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864094,716,326 - 94,818,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647112,565,054 - 12,665,962 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647112,564,617 - 12,666,229 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPM7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,146,117 - 121,250,224 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,146,093 - 121,250,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21134,584,969 - 134,689,668 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Trpm7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247319,491,157 - 9,588,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247319,490,885 - 9,588,255 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 24 18 58
Low 12 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000009065   ⟹   ENSCSAP00000007197
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2632,669,187 - 32,771,378 (+)Ensembl
RefSeq Acc Id: XM_008016620   ⟹   XP_008014811
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,644,637 - 32,772,753 (+)NCBI
Vero_WHO_p1.0NW_023666048108,383,877 - 108,505,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016621   ⟹   XP_008014812
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,644,637 - 32,772,753 (+)NCBI
Vero_WHO_p1.0NW_023666048108,383,887 - 108,505,629 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016624   ⟹   XP_008014815
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,671,635 - 32,772,753 (+)NCBI
Vero_WHO_p1.0NW_023666048108,383,877 - 108,485,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038009979   ⟹   XP_037865907
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048108,408,801 - 108,505,678 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008014811 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014812 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014815 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865907 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007197
  ENSCSAP00000007197.1
Reference Protein Sequences
RefSeq Acc Id: XP_008014811   ⟸   XM_008016620
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RF08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014812   ⟸   XM_008016621
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RF08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014815   ⟸   XM_008016624
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RF08 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007197   ⟸   ENSCSAT00000009065
RefSeq Acc Id: XP_037865907   ⟸   XM_038009979
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011086 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009065.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1010 UniProtKB/TrEMBL
  MHCK/EF2 kinase UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
  TRPM7 UniProtKB/TrEMBL
  TRPM_SLOG UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
  TRPM_tetra_sf UniProtKB/TrEMBL
NCBI Gene TRPM7 ENTREZGENE
PANTHER PTHR13800:SF8 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  LSDAT_euk UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9RF08 ENTREZGENE, UniProtKB/TrEMBL