Trpm7 (transient receptor potential cation channel subfamily M member 7) - Rat Genome Database

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Gene: Trpm7 (transient receptor potential cation channel subfamily M member 7) Chinchilla lanigera
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Symbol: Trpm7
Name: transient receptor potential cation channel subfamily M member 7
RGD ID: 9043529
Description: ENCODES a protein that exhibits actin binding (ortholog); calcium channel activity (ortholog); kinase activity (ortholog); INVOLVED IN actomyosin structure organization (ortholog); calcium ion transport (ortholog); calcium-dependent cell-matrix adhesion (ortholog); ASSOCIATED WITH adenoma (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 (ortholog); FOUND IN neuronal cell body (ortholog); plasma membrane (ortholog); ruffle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transient receptor potential cation channel, subfamily M, member 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554093,691,039 - 3,785,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554093,690,722 - 3,787,139 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trpm7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554093,691,039 - 3,785,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554093,690,722 - 3,787,139 (+)NCBIChiLan1.0ChiLan1.0
TRPM7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381550,557,158 - 50,686,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1550,552,473 - 50,686,797 (-)EnsemblGRCh38hg38GRCh38
GRCh371550,849,355 - 50,978,994 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361548,639,782 - 48,766,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 341548,639,782 - 48,766,260NCBI
Celera1527,741,918 - 27,871,940 (-)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1527,680,107 - 27,809,975 (-)NCBIHuRef
CHM1_11550,967,308 - 51,096,974 (-)NCBICHM1_1
T2T-CHM13v2.01548,365,238 - 48,493,853 (-)NCBIT2T-CHM13v2.0
Trpm7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392126,633,478 - 126,718,181 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2126,633,485 - 126,718,150 (-)EnsemblGRCm39 Ensembl
GRCm382126,791,558 - 126,876,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2126,791,565 - 126,876,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv372126,617,294 - 126,701,997 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362126,483,006 - 126,567,652 (-)NCBIMGSCv36mm8
Celera2128,031,446 - 128,117,211 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.76NCBI
Trpm7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,499,617 - 134,588,113 (-)NCBIGRCr8
mRatBN7.23114,046,258 - 114,134,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,046,258 - 114,135,190 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3117,929,825 - 118,020,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,525,352 - 126,616,298 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,185,735 - 124,276,677 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,258,189 - 119,347,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,259,467 - 119,330,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03125,783,080 - 125,871,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,320,799 - 114,410,498 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13114,227,081 - 114,234,961 (-)NCBI
Celera3112,886,549 - 112,974,913 (-)NCBICelera
Cytogenetic Map3q36NCBI
TRPM7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21639,808,442 - 39,937,735 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11543,988,947 - 44,115,197 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01529,513,220 - 29,639,506 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11547,852,859 - 47,977,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1547,853,187 - 47,977,451 (-)Ensemblpanpan1.1panPan2
TRPM7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13016,465,546 - 16,579,874 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3016,466,234 - 16,579,594 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3016,391,627 - 16,505,679 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03016,609,528 - 16,723,877 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3016,609,860 - 16,723,804 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13016,531,991 - 16,646,305 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03016,650,052 - 16,764,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03016,756,456 - 16,870,962 (-)NCBIUU_Cfam_GSD_1.0
Trpm7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864094,716,326 - 94,818,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647112,565,054 - 12,665,962 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647112,564,617 - 12,666,229 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPM7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,146,117 - 121,250,224 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,146,093 - 121,250,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21134,584,969 - 134,689,668 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRPM7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,644,637 - 32,772,753 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2632,669,187 - 32,771,378 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048108,383,877 - 108,505,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trpm7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247319,491,157 - 9,588,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247319,490,885 - 9,588,255 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000016217   ⟹   ENSCLAP00000016053
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554093,691,039 - 3,785,908 (+)Ensembl
RefSeq Acc Id: XM_005376661   ⟹   XP_005376718
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554093,690,754 - 3,787,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376664   ⟹   XP_005376721
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554093,690,754 - 3,785,910 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376665   ⟹   XP_005376722
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554093,690,722 - 3,733,573 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376718 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376721 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000016053
  ENSCLAP00000016053.1
RefSeq Acc Id: XP_005376722   ⟸   XM_005376665
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005376721   ⟸   XM_005376664
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VQ25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005376718   ⟸   XM_005376661
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VQ25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000016053   ⟸   ENSCLAT00000016217
Protein Domains
Alpha-type protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011050 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016217 ENTREZGENE
  ENSCLAT00000016217.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1010 UniProtKB/TrEMBL
  MHCK/EF2 kinase UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
  TRPM7 UniProtKB/TrEMBL
  TRPM_SLOG UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
  TRPM_tetra_sf UniProtKB/TrEMBL
NCBI Gene Trpm7 ENTREZGENE
PANTHER PTHR13800:SF8 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
  LSDAT_euk UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VQ25 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Trpm7  transient receptor potential cation channel subfamily M member 7    transient receptor potential cation channel, subfamily M, member 7  Symbol and/or name change 5135510 APPROVED