SLC8B1 (solute carrier family 8 member B1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: SLC8B1 (solute carrier family 8 member B1) Chlorocebus sabaeus
Analyze
Symbol: SLC8B1
Name: solute carrier family 8 member B1
RGD ID: 18479029
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); mitochondrial calcium ion transmembrane transport (ortholog); sodium ion transmembrane transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Cerebral Hemorrhage (ortholog); FOUND IN mitochondrial inner membrane (ortholog); sarcolemma (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/potassium/calcium exchanger 6, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111108,553,545 - 108,590,017 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11108,553,794 - 108,589,533 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037136,502,914 - 136,538,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC8B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111108,553,545 - 108,590,017 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11108,553,794 - 108,589,533 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037136,502,914 - 136,538,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC8B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812113,298,771 - 113,335,109 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12113,298,759 - 113,359,493 (-)EnsemblGRCh38hg38GRCh38
GRCh3712113,736,576 - 113,772,914 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612112,220,954 - 112,257,308 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412112,199,291 - 112,235,645NCBI
Celera12113,363,396 - 113,399,748 (-)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12110,749,040 - 110,785,386 (-)NCBIHuRef
CHM1_112113,704,819 - 113,741,134 (-)NCBICHM1_1
T2T-CHM13v2.012113,275,399 - 113,311,727 (-)NCBIT2T-CHM13v2.0
Slc8b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395120,649,233 - 120,672,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5120,649,233 - 120,672,089 (+)EnsemblGRCm39 Ensembl
GRCm385120,511,168 - 120,534,024 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5120,511,168 - 120,534,024 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,961,201 - 120,984,033 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365120,771,809 - 120,794,636 (+)NCBIMGSCv36mm8
Celera5117,595,553 - 117,618,613 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.63NCBI
Slc8b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,690,333 - 41,713,657 (-)NCBIGRCr8
mRatBN7.21236,029,759 - 36,053,087 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,029,760 - 36,053,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1237,208,956 - 37,232,225 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,820,175 - 37,843,444 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,872,639 - 36,895,908 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01241,566,980 - 41,590,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,566,981 - 41,590,244 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,421,506 - 43,444,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,227,844 - 37,250,698 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1237,689,943 - 37,713,214 (-)NCBICelera
Cytogenetic Map12q16NCBI
Slc8b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,595,604 - 9,605,271 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,594,872 - 9,617,136 (-)NCBIChiLan1.0ChiLan1.0
SLC8B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210121,387,323 - 121,421,061 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112121,384,127 - 121,417,927 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012110,903,215 - 110,936,908 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112114,286,624 - 114,319,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12114,286,624 - 114,319,683 (-)Ensemblpanpan1.1panPan2
SLC8B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12610,662,491 - 10,688,182 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2610,662,208 - 10,687,629 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2610,784,902 - 10,810,095 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02610,906,960 - 10,932,125 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,906,963 - 10,932,067 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12610,880,877 - 10,906,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,943,518 - 10,968,703 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,992,669 - 11,017,851 (-)NCBIUU_Cfam_GSD_1.0
Slc8b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118148,663,425 - 148,682,942 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366683,160,148 - 3,181,814 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC8B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1438,773,407 - 38,808,265 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11438,773,396 - 38,808,261 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,272,619 - 41,288,609 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Slc8b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,168,834 - 19,178,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474719,158,395 - 19,179,450 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000415   ⟹   ENSCSAP00000015643
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11108,553,794 - 108,589,533 (-)Ensembl
RefSeq Acc Id: XM_037996485   ⟹   XP_037852413
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037136,502,916 - 136,538,476 (+)NCBI
RefSeq Acc Id: XM_037996486   ⟹   XP_037852414
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037136,502,914 - 136,538,476 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037852413 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852414 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015643.1
Ensembl Acc Id: ENSCSAP00000015643   ⟸   ENSCSAT00000000415
RefSeq Acc Id: XP_037852414   ⟸   XM_037996486
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037852413   ⟸   XM_037996485
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S454 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000415.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1420.30 UniProtKB/TrEMBL
InterPro CaCA_antiporter UniProtKB/TrEMBL
  NaCa_Exmemb UniProtKB/TrEMBL
  NCX_ion-bd_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103239167 UniProtKB/TrEMBL
NCBI Gene SLC8B1 ENTREZGENE
PANTHER MITOCHONDRIAL SODIUM/CALCIUM EXCHANGER PROTEIN UniProtKB/TrEMBL
  NA+/CA2+ K+ INDEPENDENT EXCHANGER UniProtKB/TrEMBL
Pfam Na_Ca_ex UniProtKB/TrEMBL
UniProt A0A0D9S454 ENTREZGENE, UniProtKB/TrEMBL