CPLX2 (complexin 2) - Rat Genome Database

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Gene: CPLX2 (complexin 2) Chlorocebus sabaeus
Analyze
Symbol: CPLX2
Name: complexin 2
RGD ID: 18468210
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); SNARE binding (ortholog); syntaxin-1 binding (ortholog); INVOLVED IN synaptic vesicle exocytosis (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); psychotic disorder (ortholog); FOUND IN calyx of Held (ortholog); dendrite (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: complexin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12377,943,553 - 78,031,083 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,025,798 - 78,027,094 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666034557,841 - 646,727 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPLX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12377,943,553 - 78,031,083 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,025,798 - 78,027,094 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666034557,841 - 646,727 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CPLX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385175,796,533 - 175,884,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5175,796,310 - 175,884,021 (+)EnsemblGRCh38hg38GRCh38
GRCh375175,223,536 - 175,311,024 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,156,216 - 175,243,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 345175,156,215 - 175,243,629NCBI
Celera5171,262,673 - 171,350,105 (+)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,322,487 - 170,409,702 (+)NCBIHuRef
CHM1_15174,656,299 - 174,743,770 (+)NCBICHM1_1
T2T-CHM13v2.05176,340,215 - 176,427,717 (+)NCBIT2T-CHM13v2.0
Cplx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,455,447 - 54,531,736 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,519,162 - 54,531,730 (+)EnsemblGRCm39 Ensembl
GRCm381354,301,964 - 54,383,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,371,349 - 54,383,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv371354,472,713 - 54,485,278 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,380,974 - 54,393,539 (+)NCBIMGSCv36mm8
Celera1355,439,482 - 55,451,914 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1328.59NCBI
Cplx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,224,673 - 10,297,974 (-)NCBIGRCr8
mRatBN7.21710,219,577 - 10,292,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,222,347 - 10,293,855 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1710,237,601 - 10,245,934 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,770,838 - 11,779,143 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,234,026 - 10,242,359 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,756,871 - 10,828,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,756,285 - 10,818,835 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,880,802 - 12,952,180 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,314,592 - 16,322,938 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11716,314,591 - 16,322,938 (-)NCBI
Celera1710,295,626 - 10,303,931 (-)NCBICelera
Cytogenetic Map17p14NCBI
Cplx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,308,517 - 28,388,742 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,308,807 - 28,388,650 (+)NCBIChiLan1.0ChiLan1.0
CPLX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24170,925,024 - 171,014,363 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,064,487 - 169,153,901 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,144,671 - 171,233,028 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,041,212 - 178,128,595 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5178,115,947 - 178,128,595 (+)Ensemblpanpan1.1panPan2
CPLX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1437,203,003 - 37,275,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl437,206,082 - 37,275,954 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha437,150,959 - 37,235,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0437,569,467 - 37,653,831 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1437,394,694 - 37,478,954 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,582,684 - 37,667,026 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0438,092,304 - 38,176,702 (-)NCBIUU_Cfam_GSD_1.0
Cplx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,252,379 - 121,335,618 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936597348,203 - 357,997 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936597276,540 - 356,822 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPLX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,732,533 - 81,813,271 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,732,527 - 81,813,189 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Cplx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473314,089,018 - 14,097,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473314,085,085 - 14,170,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000007536   ⟹   ENSCSAP00000005711
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2378,025,798 - 78,027,094 (+)Ensembl
RefSeq Acc Id: XM_008015355   ⟹   XP_008013546
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12378,018,529 - 78,031,083 (+)NCBI
Vero_WHO_p1.0NW_023666034557,841 - 570,496 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008015356   ⟹   XP_008013547
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12377,943,553 - 78,031,083 (+)NCBI
Vero_WHO_p1.0NW_023666034557,841 - 646,727 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008013546 (Get FASTA)   NCBI Sequence Viewer  
  XP_008013547 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005711
  ENSCSAP00000005711.1
RefSeq Acc Id: XP_008013547   ⟸   XM_008015356
- UniProtKB: A0A0D9RAS2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008013546   ⟸   XM_008015355
- UniProtKB: A0A0D9RAS2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000005711   ⟸   ENSCSAT00000007536


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009460 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007536.1 UniProtKB/TrEMBL
Gene3D-CATH Single Helix bin UniProtKB/TrEMBL
InterPro Synaphin UniProtKB/TrEMBL
KEGG Report csab:103245019 UniProtKB/TrEMBL
NCBI Gene CPLX2 ENTREZGENE
PANTHER COMPLEXIN-2 UniProtKB/TrEMBL
  PTHR16705 UniProtKB/TrEMBL
Pfam Synaphin UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/TrEMBL
UniProt A0A0D9RAS2 ENTREZGENE, UniProtKB/TrEMBL