ARL2BP (ARF like GTPase 2 binding protein) - Rat Genome Database

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Gene: ARL2BP (ARF like GTPase 2 binding protein) Chlorocebus sabaeus
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Symbol: ARL2BP
Name: ARF like GTPase 2 binding protein (Ensembl:ADP ribosylation factor like GTPase 2 binding protein)
RGD ID: 18349394
Description: ENCODES a protein that exhibits transcription coactivator activity (inferred); INVOLVED IN positive regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN centrosome (inferred); cilium (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADP-ribosylation factor-like protein 2-binding protein; LOC103233055
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,192,283 - 43,200,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,192,287 - 43,201,681 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604733,118,182 - 33,127,306 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ARL2BP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,192,283 - 43,200,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,192,287 - 43,201,681 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604733,118,182 - 33,127,306 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ARL2BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,245,259 - 57,253,635 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,245,259 - 57,253,635 (+)EnsemblGRCh38hg38GRCh38
GRCh371657,279,171 - 57,287,547 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,836,539 - 55,845,046 (+)NCBINCBI36Build 36hg18NCBI36
Build 341655,836,538 - 55,845,046NCBI
Celera1641,778,726 - 41,787,233 (+)NCBICelera
Cytogenetic Map16q13NCBI
HuRef1643,148,688 - 43,157,185 (+)NCBIHuRef
CHM1_11658,687,284 - 58,695,791 (+)NCBICHM1_1
T2T-CHM13v2.01663,041,248 - 63,049,621 (+)NCBIT2T-CHM13v2.0
Arl2bp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,393,228 - 95,401,085 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,393,228 - 95,401,053 (+)EnsemblGRCm39 Ensembl
GRCm38894,666,600 - 94,674,457 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,666,600 - 94,674,425 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,190,655 - 97,198,322 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36897,555,884 - 97,563,551 (+)NCBIMGSCv36mm8
Celera898,995,245 - 99,002,895 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.65NCBI
Arl2bp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,342,895 - 10,352,529 (-)NCBIGRCr8
mRatBN7.21910,336,921 - 10,346,555 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,336,921 - 10,346,564 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1910,300,195 - 10,309,713 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01911,067,044 - 11,076,562 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,353,992 - 10,363,509 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,753,670 - 10,763,247 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,753,681 - 10,763,110 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01910,747,782 - 10,757,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,777,163 - 10,786,698 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1910,226,305 - 10,235,761 (-)NCBICelera
Cytogenetic Map19p13NCBI
Arl2bp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543314,887,094 - 14,894,119 (+)NCBIChiLan1.0ChiLan1.0
ARL2BP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21866,714,280 - 66,722,836 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11672,635,053 - 72,643,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01637,520,140 - 37,528,634 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11656,653,883 - 56,661,404 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1656,653,742 - 56,661,404 (+)Ensemblpanpan1.1panPan2
ARL2BP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,127,139 - 59,133,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,128,323 - 59,133,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,754,660 - 55,762,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0259,664,788 - 59,672,205 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,665,634 - 59,672,310 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,496,410 - 56,503,621 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,503,458 - 57,510,873 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,397,522 - 58,404,950 (-)NCBIUU_Cfam_GSD_1.0
Arl2bp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,236,986 - 50,245,702 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,343,336 - 9,352,065 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,343,333 - 9,352,089 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL2BP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,207,071 - 19,223,194 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,207,013 - 19,215,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,197,974 - 17,205,969 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Arl2bp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474628,798,870 - 28,805,988 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARL2BP
117 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007993429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000002958   ⟹   ENSCSAP00000001250
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl543,192,287 - 43,201,681 (+)Ensembl
RefSeq Acc Id: XM_007993429   ⟹   XP_007991620
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1543,192,283 - 43,200,113 (+)NCBI
Vero_WHO_p1.0NW_02366604733,118,182 - 33,127,306 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007991620 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001250
  ENSCSAP00000001250.1
RefSeq Acc Id: XP_007991620   ⟸   XM_007993429
- UniProtKB: A0A0D9QY11 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001250   ⟸   ENSCSAT00000002958


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004927 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002958.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1520.10 UniProtKB/TrEMBL
InterPro ARL2BP UniProtKB/TrEMBL
  BART_dom UniProtKB/TrEMBL
  BART_sf UniProtKB/TrEMBL
KEGG Report csab:103233055 UniProtKB/TrEMBL
NCBI Gene ARL2BP ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN UniProtKB/TrEMBL
  PTHR15487 UniProtKB/TrEMBL
Pfam ARL2_Bind_BART UniProtKB/TrEMBL
UniProt A0A0D9QY11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 ARL2BP  ARF like GTPase 2 binding protein  ARL2BP  ADP ribosylation factor like GTPase 2 binding protein  Symbol and/or name change 5135510 APPROVED
2022-08-09 ARL2BP  ADP ribosylation factor like GTPase 2 binding protein  LOC103233055  ADP ribosylation factor like GTPase 2 binding protein  Symbol and/or name change 5135510 APPROVED
2020-12-08 LOC103233055  ADP ribosylation factor like GTPase 2 binding protein  ARL2BP  ADP ribosylation factor like GTPase 2 binding protein  Symbol and/or name change 5135510 APPROVED