Pramel36 (PRAME like 36) - Rat Genome Database

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Gene: Pramel36 (PRAME like 36) Mus musculus
Analyze
Symbol: Pramel36
Name: PRAME like 36
RGD ID: 1624892
MGI Page MGI
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EG666089; Gm16429; PRAME family member 8; predicted gene 16429
RGD Orthologs
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39594,072,872 - 94,076,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl594,072,636 - 94,076,911 (-)EnsemblGRCm39 Ensembl
GRCm38593,925,013 - 93,929,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)EnsemblGRCm38mm10GRCm38
MGSCv37594,999,981 - 95,004,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36594,999,981 - 95,004,256 (-)NCBIMGSCv36mm8
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
triptonide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635  


Genomics

Comparative Map Data
Pramel36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39594,072,872 - 94,076,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl594,072,636 - 94,076,911 (-)EnsemblGRCm39 Ensembl
GRCm38593,925,013 - 93,929,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)EnsemblGRCm38mm10GRCm38
MGSCv37594,999,981 - 95,004,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36594,999,981 - 95,004,256 (-)NCBIMGSCv36mm8
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
Pramel36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81414,094,547 - 14,097,183 (+)NCBIGRCr8
mRatBN7.21413,790,596 - 13,793,232 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1413,790,596 - 13,793,232 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01415,448,363 - 15,451,121 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1415,448,485 - 15,451,121 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01415,386,870 - 15,389,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41415,595,222 - 15,597,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1413,815,621 - 13,818,379 (+)NCBICelera
Cytogenetic Map14p22NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:58
Interacting mature miRNAs:59
Transcripts:ENSMUST00000179824
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57717582397658215Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
12910816Ogrq2_moverall growth rate QTL 2 (mouse)57717582397658215Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57531534898019803Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_001476028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000179824   ⟹   ENSMUSP00000136364
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl594,072,937 - 94,075,731 (-)Ensembl
GRCm38.p6 Ensembl593,925,078 - 93,927,872 (-)Ensembl
Ensembl Acc Id: ENSMUST00000201400   ⟹   ENSMUSP00000143980
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl594,072,636 - 94,076,911 (-)Ensembl
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)Ensembl
RefSeq Acc Id: XM_001476028   ⟹   XP_001476078
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39594,072,872 - 94,076,898 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001476078 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000084169.6
  ENSMUSP00000136125.2
  ENSMUSP00000143980
  ENSMUSP00000143980.2
Ensembl Acc Id: ENSMUSP00000136364   ⟸   ENSMUST00000179824
Ensembl Acc Id: ENSMUSP00000143980   ⟸   ENSMUST00000201400
RefSeq Acc Id: XP_001476078   ⟸   XM_001476028
- UniProtKB: A0AAG1GHN1 (UniProtKB/TrEMBL),   J3QMM8 (UniProtKB/TrEMBL),   L7N204 (UniProtKB/TrEMBL)
- Sequence:

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-J3QMM8-F1-model_v2 AlphaFold J3QMM8 1-481 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3704105 AgrOrtholog
Ensembl Genes ENSMUSG00000094043 UniProtKB/TrEMBL
  ENSMUSG00000096230 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000096236 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000086950.6 UniProtKB/TrEMBL
  ENSMUST00000177853.2 UniProtKB/TrEMBL
  ENSMUST00000201400 ENTREZGENE
  ENSMUST00000201400.4 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  PRAME_domain UniProtKB/TrEMBL
  PRAME_family UniProtKB/TrEMBL
KEGG Report mmu:100040981 UniProtKB/TrEMBL
  mmu:666187 UniProtKB/TrEMBL
MGD MGI:3704105 ENTREZGENE
NCBI Gene Pramel36 ENTREZGENE
PANTHER PRAME-LIKE 36-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel36 PhenoGen
PIRSF PRAME UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0AAG1GHN1 ENTREZGENE, UniProtKB/TrEMBL
  J3QMM8 ENTREZGENE, UniProtKB/TrEMBL
  L7N204 ENTREZGENE
UniProt Secondary L7N204 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Pramel36  PRAME like 36  Gm16429  predicted gene 16429  Symbol and/or name change 5135510 APPROVED
2024-08-21 Gm16429  predicted gene 16429  Pramel36  PRAME like 36  Symbol and/or name change 5135510 APPROVED
2020-06-19 Pramel36  PRAME like 36  Gm16429  predicted gene 16429  Symbol and/or name change 5135510 APPROVED