Pramel36 (PRAME like 36) - Rat Genome Database

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Gene: Pramel36 (PRAME like 36) Mus musculus
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Symbol: Pramel36
Name: PRAME like 36
RGD ID: 1624892
MGI Page MGI
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EG666089; Gm16429; PRAME family member 8; predicted gene 16429
RGD Orthologs
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39594,072,872 - 94,076,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl594,072,636 - 94,076,911 (-)EnsemblGRCm39 Ensembl
GRCm38593,925,013 - 93,929,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)EnsemblGRCm38mm10GRCm38
MGSCv37594,999,981 - 95,004,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36594,999,981 - 95,004,256 (-)NCBIMGSCv36mm8
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pramel36Mousetriptonide increases expressionEXP 6480464triptonide results in increased expression of PRAMEL36 mRNACTDPMID:33045310


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pramel36Mousebiological_process involved_inND 2290270 MGIGO_REF:0000015
Pramel36Mouseproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIBAPANTHER:PTN000368795 more ...2290270 GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pramel36MouseCul2-RING ubiquitin ligase complex part_ofIBAPANTHER:PTN000368795 more ...2290270 GO_CentralGO_REF:0000033
Pramel36MouseCul2-RING ubiquitin ligase complex part_ofISOUniProtKB:P0DUQ2 and UniProtKB:Q5VXH42290270 GO_CentralGO_REF:0000119
Pramel36Mousecytoplasm is_active_inIBAPANTHER:PTN000368795 more ...2290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pramel36Mousemolecular_function enablesND 2290270 MGIGO_REF:0000015
Pramel36Mouseubiquitin-like ligase-substrate adaptor activity enablesISOUniProtKB:P0DUQ2 and UniProtKB:Q5VXH42290270 GO_CentralGO_REF:0000119
Pramel36Mouseubiquitin-like ligase-substrate adaptor activity enablesIBAPANTHER:PTN000368795 more ...2290270 GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:21873635  



Pramel36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39594,072,872 - 94,076,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl594,072,636 - 94,076,911 (-)EnsemblGRCm39 Ensembl
GRCm38593,925,013 - 93,929,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)EnsemblGRCm38mm10GRCm38
MGSCv37594,999,981 - 95,004,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36594,999,981 - 95,004,256 (-)NCBIMGSCv36mm8
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
Pramel36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81414,094,547 - 14,097,183 (+)NCBIGRCr8
mRatBN7.21413,790,596 - 13,793,232 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1413,790,596 - 13,793,232 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01415,448,363 - 15,451,121 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1415,448,485 - 15,451,121 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01415,386,870 - 15,389,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41415,595,222 - 15,597,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1413,815,621 - 13,818,379 (+)NCBICelera
Cytogenetic Map14p22NCBI

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Variants in Pramel36
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:58
Interacting mature miRNAs:59
Transcripts:ENSMUST00000179824
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 53 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57717582397658215Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse

1 to 10 of 53 rows





RefSeq Transcripts XM_001476028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000179824   ⟹   ENSMUSP00000136364
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl594,072,937 - 94,075,731 (-)Ensembl
GRCm38.p6 Ensembl593,925,078 - 93,927,872 (-)Ensembl
Ensembl Acc Id: ENSMUST00000201400   ⟹   ENSMUSP00000143980
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl594,072,636 - 94,076,911 (-)Ensembl
GRCm38.p6 Ensembl593,924,777 - 93,929,052 (-)Ensembl
RefSeq Acc Id: XM_001476028   ⟹   XP_001476078
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39594,072,872 - 94,076,898 (-)NCBI
Sequence:
Protein RefSeqs XP_001476078 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000084169.6
  ENSMUSP00000136125.2
  ENSMUSP00000143980
  ENSMUSP00000143980.2
Ensembl Acc Id: ENSMUSP00000136364   ⟸   ENSMUST00000179824
Ensembl Acc Id: ENSMUSP00000143980   ⟸   ENSMUST00000201400
RefSeq Acc Id: XP_001476078   ⟸   XM_001476028
- UniProtKB: A0AAG1GHN1 (UniProtKB/TrEMBL),   J3QMM8 (UniProtKB/TrEMBL),   L7N204 (UniProtKB/TrEMBL)
- Sequence:

Name Modeler Protein Id AA Range Protein Structure
AF-J3QMM8-F1-model_v2 AlphaFold J3QMM8 1-481 view protein structure



1 to 24 of 24 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000094043 UniProtKB/TrEMBL
  ENSMUSG00000096230 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000096236 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000086950.6 UniProtKB/TrEMBL
  ENSMUST00000177853.2 UniProtKB/TrEMBL
  ENSMUST00000201400 ENTREZGENE
  ENSMUST00000201400.4 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  PRAME_domain UniProtKB/TrEMBL
  PRAME_family UniProtKB/TrEMBL
KEGG Report mmu:100040981 UniProtKB/TrEMBL
  mmu:666187 UniProtKB/TrEMBL
MGD MGI:3704105 ENTREZGENE
NCBI Gene Pramel36 ENTREZGENE
PANTHER PRAME-LIKE 36-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel36 PhenoGen
PIRSF PRAME UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0AAG1GHN1 ENTREZGENE, UniProtKB/TrEMBL
  J3QMM8 ENTREZGENE, UniProtKB/TrEMBL
  L7N204 ENTREZGENE
UniProt Secondary L7N204 UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Pramel36  PRAME like 36  Gm16429  predicted gene 16429  Symbol and/or name change 5135510 APPROVED
2024-08-21 Gm16429  predicted gene 16429  Pramel36  PRAME like 36  Symbol and/or name change 5135510 APPROVED
2020-06-19 Pramel36  PRAME like 36  Gm16429  predicted gene 16429  Symbol and/or name change 5135510 APPROVED