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Gene: Nanos2 (nanos C2HC-type zinc finger 2) Mus musculus

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Symbol:

Nanos2

Name:

nanos C2HC-type zinc finger 2

RGD ID:

1622821

MGI Page

MGI

Description:

Enables mRNA binding activity. Involved in several processes, including germ-line stem cell population maintenance; mRNA catabolic process; and negative regulation of meiotic nuclear division. Located in P-body and perinuclear region of cytoplasm. Is expressed in early conceptus; gonad; mesonephros; and telencephalon. Orthologous to human NANOS2 (nanos C2HC-type zinc finger 2).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

n; nanos homolog 2; nanos homolog 2 (Drosophila); NOS-2; nos2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NANOS2 (nanos C2HC-type zinc finger 2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Nanos2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nanos2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NANOS2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NANOS2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nanos2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NANOS2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NANOS2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nanos2 (nanos C2HC-type zinc finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NANOS2 (nanos C2HC-type zinc finger 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Nanos2 (nanos C2HC-type zinc finger 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nanos2 (nanos homolog 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB\|ZFIN)
Caenorhabditis elegans (roundworm):	nos-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	nos	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	nos	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	nos-2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	18,721,449 - 18,722,887 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	18,721,325 - 18,722,887 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	18,987,524 - 18,988,962 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	18,987,400 - 18,988,962 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	19,572,873 - 19,574,311 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	18,146,046 - 18,147,484 (+)	NCBI		MGSCv36	mm8
Celera	7	16,399,407 - 16,400,845 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.45	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

male infertility (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (EXP)

1,2-dimethylhydrazine (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,4,4'-trichlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

all-trans-retinoic acid (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

busulfan (EXP)

fulvestrant (ISO)

mono(2-ethylhexyl) phthalate (EXP)

PCB138 (EXP)

resveratrol (ISO)

silver atom (EXP)

silver(0) (EXP)

thioacetamide (ISO)

triptonide (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEA)

germ-line stem cell population maintenance (IMP)

mRNA catabolic process (IMP)

mRNA destabilization (IEA,ISO)

negative regulation of meiotic nuclear division (IMP)

negative regulation of translation (IBA,IEA,ISO)

oogenesis (IBA)

spermatogenesis (IMP)

Cellular Component

cytoplasm (IDA,ISO)

nucleus (IEA,ISO)

P-body (IDA)

perinuclear region of cytoplasm (IBA,IDA,ISO,ISS)

Molecular Function

enzyme activator activity (IEA,ISO)

mRNA binding (IBA,IDA)

protein binding (IPI)

zinc ion binding (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal gametogenesis (IAGP)

abnormal male germ cell apoptosis (IAGP)

abnormal male germ cell morphology (IAGP)

abnormal male meiosis (IAGP)

abnormal male reproductive system physiology (IAGP)

abnormal seminiferous tubule morphology (IAGP)

abnormal skin coloration (IEA)

abnormal spermatogenesis (IAGP)

azoospermia (IAGP)

decreased male germ cell number (IAGP)

decreased testis weight (IAGP)

increased blood urea nitrogen level (IEA)

male infertility (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12947200	PMID:14656712	PMID:14681479	PMID:16806845	PMID:17138666	PMID:18281459	PMID:19745153	PMID:19818747	PMID:20133598	PMID:20159962	PMID:20652721	PMID:20707993
PMID:20833365	PMID:20965161	PMID:21115610	PMID:21267068	PMID:21504946	PMID:21621532	PMID:21674058	PMID:21873635	PMID:21991325	PMID:22071108	PMID:22102605	PMID:22190708
PMID:22262692	PMID:22360967	PMID:22393026	PMID:22448252	PMID:23034635	PMID:23221368	PMID:23284137	PMID:23497137	PMID:24038201	PMID:24183939	PMID:24576537	PMID:24850856
PMID:25142465	PMID:25344072	PMID:25416063	PMID:25605784	PMID:25725066	PMID:26120033	PMID:26589352	PMID:26609159	PMID:27072294	PMID:28118982	PMID:28128212	PMID:28162974
PMID:28341395	PMID:28760667	PMID:29339164	PMID:29501710	PMID:29545285	PMID:30322389	PMID:30679547	PMID:31095680	PMID:32339196	PMID:32452519	PMID:32929012	PMID:33199444
PMID:33199844	PMID:33912935	PMID:34278268	PMID:34401671	PMID:34494084	PMID:34686326	PMID:35394008	PMID:35426065	PMID:35705038	PMID:36796745	PMID:38355793

Genomics

Comparative Map Data

Nanos2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	18,721,449 - 18,722,887 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	18,721,325 - 18,722,887 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	18,987,524 - 18,988,962 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	18,987,400 - 18,988,962 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	19,572,873 - 19,574,311 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	18,146,046 - 18,147,484 (+)	NCBI		MGSCv36	mm8
Celera	7	16,399,407 - 16,400,845 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.45	NCBI

NANOS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	45,913,214 - 45,914,778 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	45,913,214 - 45,914,778 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	46,416,472 - 46,418,036 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	51,108,312 - 51,109,876 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	51,108,314 - 51,109,876	NCBI
Celera	19	43,221,499 - 43,223,063 (-)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	42,844,824 - 42,846,388 (-)	NCBI		HuRef
CHM1_1	19	46,418,965 - 46,420,529 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	48,740,655 - 48,742,219 (-)	NCBI		T2T-CHM13v2.0

Nanos2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	87,763,716 - 87,765,176 (+)	NCBI		GRCr8
mRatBN7.2	1	78,635,668 - 78,637,128 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	78,635,668 - 78,637,128 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	84,024,658 - 84,026,118 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,582,270 - 92,583,730 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	85,779,762 - 85,781,222 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,894,450 - 79,895,910 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,894,450 - 79,895,910 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	81,155,091 - 81,156,551 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,341,105 - 78,342,565 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	73,101,755 - 73,103,215 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Nanos2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955574	333,116 - 333,529 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955574	333,007 - 333,529 (-)	NCBI	ChiLan1.0	ChiLan1.0

NANOS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	52,077,294 - 52,086,515 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	53,948,686 - 53,957,908 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	42,922,655 - 42,924,679 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	51,458,466 - 51,460,116 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	51,459,529 - 51,459,945 (-)	Ensembl	panpan1.1		panPan2

NANOS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	109,716,634 - 109,717,701 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	109,716,699 - 109,717,115 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	109,202,035 - 109,203,102 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	110,251,017 - 110,252,084 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	110,251,082 - 110,251,498 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	109,925,501 - 109,926,568 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	109,560,220 - 109,561,287 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	110,428,944 - 110,430,011 (+)	NCBI		UU_Cfam_GSD_1.0

Nanos2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	17,884,913 - 17,885,868 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936706	2,232,265 - 2,232,657 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936706	2,232,265 - 2,232,657 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NANOS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	52,219,418 - 52,219,834 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	52,218,889 - 52,219,834 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	47,481,251 - 47,481,667 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NANOS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	39,359,581 - 39,361,699 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	39,360,640 - 39,361,056 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	19,001,703 - 19,003,343 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nanos2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624832	7,309,334 - 7,310,645 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nanos2
63 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	339
Count of miRNA genes:	265
Interacting mature miRNAs:	293
Transcripts:	ENSMUST00000063563
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300722	Sle3_m	systemic lupus erythmatosus susceptibility 3 (mouse)			Not determined		7	3511728	87142720	Mouse
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6502999	133501729	Mouse
4141566	Femwf8_m	femur work to failure 8 (mouse)			Not determined			13032485	47032621	Mouse
38501068	Tip1_m	tuberculosis immunophenotype 1, spleen CFU (mouse)					7	3602999	72549748	Mouse
1301115	Lrdm1_m	lymphoproliferation (Fas) renal disease modifier 1 (mouse)			Not determined		7	3352048	24879418	Mouse
25314314	Sccor1_m	synaptonemal complex length to mean MLH1 count ratio 1 (mouse)					7	13333925	47349748	Mouse
12904941	Edlmmq6_m	extensor digitorum longus muscle mass QTL 6 (mouse)					7	1	21821047	Mouse
1301177	Vent3_m	ventricular size 3 (mouse)			Not determined		7	1	20511925	Mouse
10054067	Sle20_m	systematic lupus erythematosus susceptibility 20 (mouse)			Not determined		7	1	20511925	Mouse
10449139	Eosn1_m	eosinophil differential 1 (mouse)					7	12480877	46480877	Mouse
12904948	Tammq5_m	tibialis anterior muscle mass QTL 5 (mouse)					7	1	21821047	Mouse
11522751	Cocia17_m	cocaine-induced activity, QTL 17 (mouse)					7	13135204	47135204	Mouse
12792978	Fbmd3_m	femoral bone mineral density 3, females only (mouse)					7	7050288	142367832	Mouse
1301572	Sluc30_m	susceptibility to lung cancer 30 (mouse)			Not determined		7	2431696	36431844	Mouse
1357699	Nhdlq6_m	non-HDL QTL 6 (mouse)			Not determined		7	9988867	43988984	Mouse
10449158	Eosn3_m	eosinophil differential 3 (mouse)					7	12480877	46480877	Mouse
1558893	Spir1_m	Streptococcus pneumoniae infection resistance 1 (mouse)			Not determined		7	10305798	44305936	Mouse
12904953	Gmmq5_m	gastrocnemius muscle mass QTL 5 (mouse)					7	1	21821047	Mouse
1302188	Lxw6_m	lupus BXSB x NZW 6 (mouse)			Not determined		7	1	21698146	Mouse
1559016	Drsi_m	DCC-related Spp1 induction (mouse)			Not determined		7	16637293	49159331	Mouse

Markers in Region

Nanos2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	7	19,573,137 - 19,573,629	UniSTS	GRCm37
Celera	7	16,399,671 - 16,400,163	UniSTS
Cytogenetic Map	7	A3	UniSTS
cM Map	7		UniSTS

UniSTS:489564

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	18,987,559 - 18,988,324	UniSTS	GRCm38
MGSCv37	7	19,572,908 - 19,573,673	UniSTS	GRCm37
Celera	7	16,399,442 - 16,400,207	UniSTS
Cytogenetic Map	7	A3	UniSTS

Nanos2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	18,987,788 - 18,988,280	UniSTS	GRCm38
MGSCv37	7	19,573,137 - 19,573,629	UniSTS	GRCm37
Celera	7	16,399,671 - 16,400,163	UniSTS
Cytogenetic Map	7	A3	UniSTS
cM Map	7		UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_194064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB095972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC170864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ936992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000063563 ⟹ ENSMUSP00000069765

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	18,721,325 - 18,722,887 (+)	Ensembl
GRCm38.p6 Ensembl	7	18,987,400 - 18,988,962 (+)	Ensembl

RefSeq Acc Id:

NM_194064 ⟹ NP_918953

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	18,721,449 - 18,722,887 (+)	NCBI
GRCm38	7	18,987,524 - 18,988,962 (+)	ENTREZGENE
MGSCv37	7	19,572,873 - 19,574,311 (+)	RGD
Celera	7	16,399,407 - 16,400,845 (+)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

AAAACTCCTGCTCCTGCCCTCTGACCTCACAGCCCCTGCTCCCCAGTCCCTCTCCAGTGCCCAC
AGCCACATTTAAGTGCCATGGACCTACCGCCCTTTGACATGTGGAGAGACTACTTTAACCTGAG
CCAGGTGGTGATGGATATAATTCAGAGCCGGAAGCAAAGACAGGAGGGTGAGGTAGCTGAGGAG
CCCAACTCCAGGCCCCAGGAGAAGAGTGAGCAGGACCTGGAGGGCTACCCTGGATGTCTGCCTA
CCATATGCAACTTCTGCAAGCACAATGGGGAGTCTCGTCACGTCTACACCTCACACCAGCTGAA
GACGCCTGAAGGGGTGGTTGTGTGTCCCATCCTGAGGCACTATGTGTGTCCTCTATGTGGAGCC
ACCGGCGACCAGGCTCATACACTCAAGTATTGTCCACTCAACAGCAGTCAGCAGTCTCTCTACC
GACGCAGTGGGCGAAACTCAGCTGGTCGCAGAGTCAAGCGATAATTGAGACCCTGTGAGGTACC
TGTCACCCACAACCCACACCCTCCTGCTTCTGACCCTAGTCCCCTCTGCTCTGCTCACCCAGCC
CGCTGGAGGTCCCCCGATCTCAACGTTTTCTGTGCCTTCAGGATCCTGAAACACTGGGAAATGC
TGGCAGCCCAGACTGTGTGTCTCAGACATTCCTGGTACTGTGAGAACCCTTCTCCATGGACCGT
GTGAGTCTTGGTGGTTTCTTTTGGATTGTGAGGGCCTGGTGATGACTTCTCGGTTCCTCTCTAA
AGATCCCTTGGGGGGGAGGGGTCCTTGGATTTGCTATCCTATAGAGTCAGTGTGCTCTGACAGG
CCAGTCTTCAGAACCTGGGGACAGTGCCAGAGACTGATCCTGATCGTCACTGCCAAGAAGTGGA
TGTTGGTACTGACTATGAGACCATCCATCTATCTTCACCTTTTTTCAGCATCTGCAGACTCAAA
CTTCTCCATGGACCATTCACGTTCAGCTCCTTAGTTCCTTGAACATGGCCATGTCCATCAGGAA
TAAGAGGAAGGTTACAGGAACTAGAGGAGGGTTGGGACCCTCTGGGAAGGCTGCCAGACCTTTG
TAACTTCAGACTGCCTCGGGTGAGCAGAAGCCCACAGATTTCACTTCATCACTAACCATGGTTC
ACTCTATTCCTGCCCCCAGCCCCACTCGTTGATGGATCCCTGACTCCCGGTGGGTGAGAGACAT
TCTCTCTCTTCTACCCATCCAATATAGTTGAGTGTGTTACGTCAGTGTGTGTCCCATGGTGAGA
AGAGTCTGAGACCTCATGGGACTGATGACTGCTTAGGTTTTAATTTTAGGGGCAGAGAAGAATG
CCAGTTGGGTTTTATGCTATCTAGGAGGTTGGCTTGGAAATGGGATGAGGGTGGAGGAGGGGTG
TCTGCTGCTGAATAAAGCGTTGTTAGTCTAC

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Protein Sequences


Protein RefSeqs	NP_918953	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AFN66120	(Get FASTA)	NCBI Sequence Viewer
	BAC82557	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000069765
	ENSMUSP00000069765.8
GenBank Protein	P60322	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_918953 ⟸ NM_194064
- UniProtKB:	F8VQ09 (UniProtKB/Swiss-Prot), P60322 (UniProtKB/Swiss-Prot), I6ZHM2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLPPFDMWRDYFNLSQVVMDIIQSRKQRQEGEVAEEPNSRPQEKSEQDLEGYPGCLPTICNFC KHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSSQQSLYRRSGRN SAGRRVKR hide sequence

Ensembl Acc Id:

ENSMUSP00000069765 ⟸ ENSMUST00000063563

Protein Domains

Nanos-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P60322-F1-model_v2	AlphaFold	P60322	1-136	view protein structure

Promoters

RGD ID:

6892020

Promoter ID:

EPDNEW_M9461

Type:

initiation region

Name:

Nanos2_1

Description:

Mus musculus nanos C2HC-type zinc finger 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	18,987,568 - 18,987,628	EPDNEW

RGD ID:

6841612

Promoter ID:

MM_KWN:49011

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour

Transcripts:

NM_194064

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	7	19,573,246 - 19,573,746 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2676627	AgrOrtholog
Ensembl Genes	ENSMUSG00000051965	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000063563	ENTREZGENE
	ENSMUST00000063563.9	UniProtKB/Swiss-Prot
Gene3D-CATH	4.10.60.30	UniProtKB/Swiss-Prot
InterPro	Nanos/Xcar2	UniProtKB/Swiss-Prot
	Nanos_sf	UniProtKB/Swiss-Prot
	Znf_nanos-typ	UniProtKB/Swiss-Prot
KEGG Report	mmu:378430	UniProtKB/Swiss-Prot
MGD	MGI:2676627	ENTREZGENE
NCBI Gene	378430	ENTREZGENE
PANTHER	PTHR12887	UniProtKB/Swiss-Prot
Pfam	zf-nanos	UniProtKB/Swiss-Prot
PhenoGen	Nanos2	PhenoGen
PROSITE	ZF_NANOS	UniProtKB/Swiss-Prot
UniProt	F8VQ09	ENTREZGENE
	I6ZHM2	ENTREZGENE, UniProtKB/TrEMBL
	NANO2_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	F8VQ09	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-10-31	Nanos2	nanos C2HC-type zinc finger 2		nanos homolog 2 (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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