Rnf217 (ring finger protein 217) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Rnf217 (ring finger protein 217) Mus musculus
Analyze
Symbol: Rnf217
Name: ring finger protein 217
RGD ID: 1620489
MGI Page MGI
Description: Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in adrenal gland; cerebral cortex intermediate zone; cerebral cortex mantle layer; cerebral cortex ventricular layer; and vertebral axis musculature. Orthologous to human RNF217 (ring finger protein 217).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI853829; AU016819; E3 ubiquitin-protein ligase RNF217; expressed sequence AI853829; IBR domain containing 1; IBR domain-containing protein 1; Ibrd; Ibrdc1; probable E3 ubiquitin-protein ligase RNF217
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391031,377,883 - 31,485,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1031,369,189 - 31,485,180 (-)EnsemblGRCm39 Ensembl
GRCm381031,501,887 - 31,609,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1031,493,193 - 31,609,184 (-)EnsemblGRCm38mm10GRCm38
MGSCv371031,221,693 - 31,329,531 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361031,191,301 - 31,300,328 (-)NCBIMGSCv36mm8
Celera1032,427,225 - 32,533,457 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1017.45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf217Mousemultiple sclerosis  ISORNF217 (Homo sapiens)8554872ClinVar Annotator: match by term: Multiple sclerosis and susceptibility toClinVar 

1 to 20 of 64 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf217Mouse(-)-epigallocatechin 3-gallate multiple interactionsISORNF217 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RNF217 mRNACTDPMID:22079256
Rnf217Mouse(1->4)-beta-D-glucan multiple interactionsEXP 6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RNF217 mRNACTDPMID:36331819
Rnf217Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of RNF217 mRNACTDPMID:22206623
Rnf217Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RNF217 mRNACTDPMID:19933214
Rnf217Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORnf217 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of RNF217 mRNACTDPMID:32109520
Rnf217Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORNF217 (Homo sapiens)6480464[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of RNF217 mRNACTDPMID:29704546
Rnf217Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of RNF217 mRNACTDPMID:24680724
Rnf217Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of RNF217 mRNACTDPMID:39298647
Rnf217Mouse4-hydroxyphenyl retinamide decreases expressionEXP 6480464Fenretinide results in decreased expression of RNF217 mRNACTDPMID:28973697
Rnf217Mouse6-propyl-2-thiouracil increases expressionISORnf217 (Rattus norvegicus)6480464Propylthiouracil results in increased expression of RNF217 mRNACTDPMID:24780913
Rnf217Mousearistolochic acid A decreases expressionISORNF217 (Homo sapiens)6480464aristolochic acid I results in decreased expression of RNF217 mRNACTDPMID:33212167
Rnf217Mouseatrazine affects methylationISORnf217 (Rattus norvegicus)6480464Atrazine affects the methylation of RNF217 geneCTDPMID:35440735
Rnf217Mousebelinostat multiple interactionsISORNF217 (Homo sapiens)6480464[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF217 mRNACTDPMID:27188386
Rnf217Mousebelinostat increases expressionISORNF217 (Homo sapiens)6480464belinostat results in increased expression of RNF217 mRNACTDPMID:26272509
Rnf217Mousebenzo[a]pyrene increases methylationISORNF217 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of RNF217 5' UTRCTDPMID:27901495
Rnf217Mousebis(2-ethylhexyl) phthalate decreases expressionEXP 6480464Diethylhexyl Phthalate results in decreased expression of RNF217 mRNACTDPMID:34319233
Rnf217Mousebisphenol A affects expressionISORnf217 (Rattus norvegicus)6480464bisphenol A affects the expression of RNF217 mRNACTDPMID:25181051
Rnf217Mousebisphenol A affects methylationISORNF217 (Homo sapiens)6480464bisphenol A affects the methylation of RNF217 geneCTDPMID:31601247
Rnf217Mousebisphenol A multiple interactionsISORNF217 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] affects the methylation of RNF217 geneCTDPMID:31601247
Rnf217Mousebisphenol A increases methylationISORnf217 (Rattus norvegicus)6480464bisphenol A results in increased methylation of RNF217 geneCTDPMID:28505145

1 to 20 of 64 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf217Mouseprotein ubiquitination involved_inIEAUniPathway:UPA001432290270 UniProtGO_REF:0000041
Rnf217Mouseubiquitin-dependent protein catabolic process involved_inIBAPANTHER:PTN000188395 more ...2290270 GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf217Mousecytoplasm located_inIEAUniProtKB-SubCell:SL-00862290270 UniProtGO_REF:0000044
Rnf217Mousecytoplasm is_active_inIBAPANTHER:PTN000188395 more ...2290270 GO_CentralGO_REF:0000033
Rnf217Mousemembrane located_inIEAUniProtKB-SubCell:SL-01622290270 UniProtGO_REF:0000044
Rnf217Mouseubiquitin ligase complex part_ofIBAPANTHER:PTN000188395 more ...2290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnf217Mouseubiquitin conjugating enzyme binding enablesIBAPANTHER:PTN000188395 more ...2290270 GO_CentralGO_REF:0000033
Rnf217Mouseubiquitin protein ligase activity enablesIBAPANTHER:PTN000188395 more ...2290270 GO_CentralGO_REF:0000033
Rnf217Mouseubiquitin-protein transferase activity enablesIEAInterPro:IPR0311272290270 InterProGO_REF:0000002
Rnf217Mousezinc ion binding enablesIEAUniProtKB-KW:KW-08632290270 UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548   PMID:10725249   PMID:10922068   PMID:15782199   PMID:21267068   PMID:21677750   PMID:21873635   PMID:33895792   PMID:34321999   PMID:38355793  



Rnf217
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391031,377,883 - 31,485,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1031,369,189 - 31,485,180 (-)EnsemblGRCm39 Ensembl
GRCm381031,501,887 - 31,609,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1031,493,193 - 31,609,184 (-)EnsemblGRCm38mm10GRCm38
MGSCv371031,221,693 - 31,329,531 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361031,191,301 - 31,300,328 (-)NCBIMGSCv36mm8
Celera1032,427,225 - 32,533,457 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1017.45NCBI
RNF217
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386124,962,437 - 125,092,634 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6124,962,437 - 125,092,633 (+)EnsemblGRCh38hg38GRCh38
GRCh376125,283,583 - 125,413,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366125,346,213 - 125,446,360 (+)NCBINCBI36Build 36hg18NCBI36
Build 346125,346,212 - 125,446,359NCBI
Celera6126,049,522 - 126,149,701 (+)NCBICelera
Cytogenetic Map6q22.31NCBI
HuRef6122,881,176 - 122,981,254 (+)NCBIHuRef
CHM1_16125,567,969 - 125,668,114 (+)NCBICHM1_1
T2T-CHM13v2.06126,150,465 - 126,280,671 (+)NCBIT2T-CHM13v2.0
Rnf217
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,835,741 - 27,927,805 (+)NCBIGRCr8
mRatBN7.2126,016,668 - 26,108,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl126,015,728 - 26,108,736 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx125,764,307 - 25,856,182 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0131,764,134 - 31,856,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0125,964,885 - 26,056,790 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0128,301,960 - 28,391,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl128,301,922 - 28,390,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0129,676,521 - 29,846,859 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4126,630,933 - 26,723,874 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1126,556,135 - 26,727,060 (+)NCBI
Celera124,711,297 - 24,803,602 (+)NCBICelera
Cytogenetic Map1p11NCBI
Rnf217
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554366,458,088 - 6,566,112 (+)NCBIChiLan1.0ChiLan1.0
RNF217
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25144,952,595 - 145,081,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16142,856,546 - 142,985,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06122,747,128 - 122,875,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16126,878,597 - 127,001,757 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6126,867,604 - 126,992,867 (+)Ensemblpanpan1.1panPan2
RNF217
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1163,902,985 - 64,094,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl163,962,515 - 64,085,011 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha164,771,771 - 64,904,604 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0164,169,156 - 64,302,061 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl164,168,719 - 64,294,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1164,100,868 - 64,233,594 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0163,830,960 - 64,020,201 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0164,538,810 - 64,671,819 (+)NCBIUU_Cfam_GSD_1.0
Rnf217
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946114,090,629 - 114,132,623 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366394,295,293 - 4,325,468 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF217
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl137,788,472 - 37,912,122 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1137,784,359 - 37,912,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2141,674,373 - 41,734,266 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF217
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11348,612,687 - 48,743,821 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604020,922,993 - 21,056,572 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf217
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247986,390,200 - 6,499,471 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Rnf217
4145 total Variants

Predicted Target Of
Summary Value
Count of predictions:182
Count of miRNA genes:165
Interacting mature miRNAs:169
Transcripts:ENSMUST00000081989
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse

1 to 10 of 32 rows
15.MMHAP12FLE3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381031,502,292 - 31,502,490UniSTSGRCm38
MGSCv371031,222,098 - 31,222,296UniSTSGRCm37
Celera1032,427,630 - 32,427,828UniSTS
Cytogenetic Map10A4UniSTS
Whitehead_YAC10 UniSTS
D10Mit155  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381031,550,768 - 31,550,915UniSTSGRCm38
MGSCv371031,270,574 - 31,270,721UniSTSGRCm37
Celera1032,476,104 - 32,476,251UniSTS
Cytogenetic Map10A4UniSTS
cM Map1023.0UniSTS
Whitehead Genetic1017.5UniSTS
Whitehead_YAC10 UniSTS
AI853829  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381031,501,928 - 31,502,011UniSTSGRCm38
MGSCv371031,221,734 - 31,221,817UniSTSGRCm37
Celera1032,427,266 - 32,427,349UniSTS
Cytogenetic Map10A4UniSTS
Whitehead/MRC_RH10405.8UniSTS
Whitehead/MRC_RH10408.19UniSTS







Ensembl Acc Id: ENSMUST00000081989   ⟹   ENSMUSP00000080650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1031,369,189 - 31,485,180 (-)Ensembl
GRCm38.p6 Ensembl1031,493,193 - 31,609,184 (-)Ensembl
RefSeq Acc Id: NM_001146349   ⟹   NP_001139821
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391031,377,883 - 31,485,721 (-)NCBI
GRCm381031,501,887 - 31,609,725 (-)ENTREZGENE
MGSCv371031,221,693 - 31,329,531 (-)RGD
Celera1032,427,225 - 32,533,457 (-)RGD
cM Map10 ENTREZGENE
Sequence:
Protein RefSeqs NP_001139821 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3YYI7 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000080650
  ENSMUSP00000080650.6
RefSeq Acc Id: NP_001139821   ⟸   NM_001146349
- UniProtKB: D3YYI7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000080650   ⟸   ENSMUST00000081989

Name Modeler Protein Id AA Range Protein Structure
AF-D3YYI7-F1-model_v2 AlphaFold D3YYI7 1-515 view protein structure

RGD ID:6818860
Promoter ID:MM_KWN:3860
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000081989,   NM_001146349
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361031,328,486 - 31,329,697 (-)MPROMDB
RGD ID:8671750
Promoter ID:EPDNEW_M13906
Type:initiation region
Name:Rnf217_1
Description:Mus musculus ring finger protein 217 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381031,609,725 - 31,609,785EPDNEW


1 to 23 of 23 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000063760 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000081989 ENTREZGENE
  ENSMUST00000081989.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.1750 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro BRcat_RBR_RNF217 UniProtKB/Swiss-Prot
  E3_UB_ligase_RBR UniProtKB/Swiss-Prot
  IBR_dom UniProtKB/Swiss-Prot
  Rcat_RBR_RNF217 UniProtKB/Swiss-Prot
  RNF217_RBR_vRING-HC UniProtKB/Swiss-Prot
  TRIAD_supradom UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report mmu:268291 UniProtKB/Swiss-Prot
MGD MGI:3610311 ENTREZGENE
NCBI Gene 268291 ENTREZGENE
PANTHER PTHR11685 UniProtKB/Swiss-Prot
Pfam IBR UniProtKB/Swiss-Prot
  IBR_1 UniProtKB/Swiss-Prot
PhenoGen Rnf217 PhenoGen
PROSITE TRIAD UniProtKB/Swiss-Prot
SMART IBR UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
UniProt D3YYI7 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-09 Rnf217  ring finger protein 217  AI853829  expressed sequence AI853829  Data merged from RGD:1610556 737654 PROVISIONAL