RNF217 (ring finger protein 217) - Rat Genome Database

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Gene: RNF217 (ring finger protein 217) Sus scrofa
Analyze
Symbol: RNF217
Name: ring finger protein 217
RGD ID: 13848287
Description: ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin conjugating enzyme binding (inferred); INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (inferred); protein polyubiquitination (inferred); protein ubiquitination (inferred); ASSOCIATED WITH genetic disease (ortholog); multiple sclerosis (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable E3 ubiquitin-protein ligase RNF217
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl137,788,472 - 37,912,122 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1137,784,359 - 37,912,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2141,674,373 - 41,734,266 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
membrane  (IEA)
ubiquitin ligase complex  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF217
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl137,788,472 - 37,912,122 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1137,784,359 - 37,912,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2141,674,373 - 41,734,266 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF217
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386124,962,437 - 125,092,634 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6124,962,437 - 125,092,633 (+)EnsemblGRCh38hg38GRCh38
GRCh376125,283,583 - 125,413,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366125,346,213 - 125,446,360 (+)NCBINCBI36Build 36hg18NCBI36
Build 346125,346,212 - 125,446,359NCBI
Celera6126,049,522 - 126,149,701 (+)NCBICelera
Cytogenetic Map6q22.31NCBI
HuRef6122,881,176 - 122,981,254 (+)NCBIHuRef
CHM1_16125,567,969 - 125,668,114 (+)NCBICHM1_1
T2T-CHM13v2.06126,150,465 - 126,280,671 (+)NCBIT2T-CHM13v2.0
Rnf217
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391031,377,883 - 31,485,721 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1031,369,189 - 31,485,180 (-)EnsemblGRCm39 Ensembl
GRCm381031,501,887 - 31,609,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1031,493,193 - 31,609,184 (-)EnsemblGRCm38mm10GRCm38
MGSCv371031,221,693 - 31,329,531 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361031,191,301 - 31,300,328 (-)NCBIMGSCv36mm8
Celera1032,427,225 - 32,533,457 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1017.45NCBI
Rnf217
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,835,741 - 27,927,805 (+)NCBIGRCr8
mRatBN7.2126,016,668 - 26,108,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl126,015,728 - 26,108,736 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx125,764,307 - 25,856,182 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0131,764,134 - 31,856,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0125,964,885 - 26,056,790 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0128,301,960 - 28,391,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl128,301,922 - 28,390,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0129,676,521 - 29,846,859 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4126,630,933 - 26,723,874 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1126,556,135 - 26,727,060 (+)NCBI
Celera124,711,297 - 24,803,602 (+)NCBICelera
Cytogenetic Map1p11NCBI
Rnf217
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554366,458,088 - 6,566,112 (+)NCBIChiLan1.0ChiLan1.0
RNF217
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25144,952,595 - 145,081,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16142,856,546 - 142,985,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06122,747,128 - 122,875,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16126,878,597 - 127,001,757 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6126,867,604 - 126,992,867 (+)Ensemblpanpan1.1panPan2
RNF217
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1163,902,985 - 64,094,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl163,962,515 - 64,085,011 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha164,771,771 - 64,904,604 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0164,169,156 - 64,302,061 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl164,168,719 - 64,294,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1164,100,868 - 64,233,594 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0163,830,960 - 64,020,201 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0164,538,810 - 64,671,819 (+)NCBIUU_Cfam_GSD_1.0
Rnf217
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946114,090,629 - 114,132,623 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366394,295,293 - 4,325,468 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF217
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11348,612,687 - 48,743,821 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604020,922,993 - 21,056,572 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf217
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247986,390,200 - 6,499,471 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RNF217
2460 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 2
Low 10 4 2 5 2 22 2 3 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000022320   ⟹   ENSSSCP00000020793
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl137,793,470 - 37,912,122 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071767   ⟹   ENSSSCP00000060621
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl137,788,472 - 37,834,758 (-)Ensembl
RefSeq Acc Id: XM_021072754   ⟹   XP_020928413
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1137,784,359 - 37,912,122 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020928413   ⟸   XM_021072754
- UniProtKB: A0A8D0X3I1 (UniProtKB/TrEMBL),   I3L9T0 (UniProtKB/TrEMBL),   A0A8D1RRE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000020793   ⟸   ENSSSCT00000022320
RefSeq Acc Id: ENSSSCP00000060621   ⟸   ENSSSCT00000071767
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021149 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030046428 UniProtKB/TrEMBL
  ENSSSCG00040073481 UniProtKB/TrEMBL
  ENSSSCG00045008405 UniProtKB/TrEMBL
  ENSSSCG00050008343 UniProtKB/TrEMBL
  ENSSSCG00055025009 UniProtKB/TrEMBL
  ENSSSCG00060016609 UniProtKB/TrEMBL
  ENSSSCG00065012182 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000022320 ENTREZGENE
  ENSSSCT00000022320.3 UniProtKB/TrEMBL
  ENSSSCT00000071767.2 UniProtKB/TrEMBL
  ENSSSCT00030064793.1 UniProtKB/TrEMBL
  ENSSSCT00040101397.1 UniProtKB/TrEMBL
  ENSSSCT00045014151.1 UniProtKB/TrEMBL
  ENSSSCT00050011357.1 UniProtKB/TrEMBL
  ENSSSCT00055049466.1 UniProtKB/TrEMBL
  ENSSSCT00060022153.1 UniProtKB/TrEMBL
  ENSSSCT00065016204.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1750 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro BRcat_RBR_RNF217 UniProtKB/TrEMBL
  E3_UB_ligase_RBR UniProtKB/TrEMBL
  IBR_dom UniProtKB/TrEMBL
  Rcat_RBR_RNF217 UniProtKB/TrEMBL
  RNF217_RBR_vRING-HC UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene RNF217 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF217 UniProtKB/TrEMBL
  PTHR11685 UniProtKB/TrEMBL
Pfam IBR UniProtKB/TrEMBL
PROSITE TRIAD UniProtKB/TrEMBL
SMART IBR UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A5G2Q8Q6_PIG UniProtKB/TrEMBL
  A0A8D0X3I1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RRE1 ENTREZGENE, UniProtKB/TrEMBL
  I3L9T0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:103162 ENTREZGENE