Mturn (maturin, neural progenitor differentiation regulator homolog (Xenopus)) - Rat Genome Database

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Gene: Mturn (maturin, neural progenitor differentiation regulator homolog (Xenopus)) Mus musculus
Analyze
Symbol: Mturn
Name: maturin, neural progenitor differentiation regulator homolog (Xenopus)
RGD ID: 1619177
MGI Page MGI
Description: Involved in positive regulation of megakaryocyte differentiation. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; ileum; male reproductive gland or organ; notochord; and retina. Orthologous to human MTURN (maturin, neural progenitor differentiation regulator homolog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410066E13Rik; AI448550; B230212L03Rik; hypothetical protein LOC68235; maturin; maturin neural progenitor differentiation regulator protein homolog; UPF0452 protein C7orf41 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,658,609 - 54,680,840 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,658,609 - 54,680,836 (+)EnsemblGRCm39 Ensembl
GRCm38654,681,624 - 54,703,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,681,624 - 54,703,851 (+)EnsemblGRCm38mm10GRCm38
MGSCv37654,631,766 - 54,650,400 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36654,611,350 - 54,629,984 (+)NCBIMGSCv36mm8
Celera655,210,674 - 55,229,300 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:22008794  
PMID:24095902   PMID:24194600   PMID:24681962   PMID:27626380   PMID:31957809   PMID:33506033   PMID:34321999  


Genomics

Comparative Map Data
Mturn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,658,609 - 54,680,840 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,658,609 - 54,680,836 (+)EnsemblGRCm39 Ensembl
GRCm38654,681,624 - 54,703,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,681,624 - 54,703,851 (+)EnsemblGRCm38mm10GRCm38
MGSCv37654,631,766 - 54,650,400 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36654,611,350 - 54,629,984 (+)NCBIMGSCv36mm8
Celera655,210,674 - 55,229,300 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.07NCBI
MTURN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,134,986 - 30,162,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,134,986 - 30,162,762 (+)EnsemblGRCh38hg38GRCh38
GRCh37730,174,602 - 30,202,378 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,141,077 - 30,168,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera730,163,906 - 30,191,735 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,056,754 - 30,084,572 (+)NCBIHuRef
CHM1_1730,174,629 - 30,202,485 (+)NCBICHM1_1
T2T-CHM13v2.0730,272,637 - 30,300,448 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2730,224,343 - 30,252,173 (+)NCBI
Mturn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,137,825 - 85,158,790 (+)NCBIGRCr8
mRatBN7.2483,807,528 - 83,828,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,807,579 - 83,824,950 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,028,677 - 89,049,590 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,804,099 - 84,825,012 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,219,027 - 83,239,949 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,854,341 - 84,875,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,854,386 - 84,871,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,514,247 - 149,531,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4483,087,757 - 83,105,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera478,676,774 - 78,694,109 (+)NCBICelera
Cytogenetic Map4q24NCBI
Mturn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541031,435,282 - 31,445,861 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541031,435,282 - 31,450,450 (+)NCBIChiLan1.0ChiLan1.0
MTURN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2634,955,350 - 34,983,213 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1783,280,078 - 83,307,941 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0730,766,592 - 30,794,436 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1730,884,473 - 30,909,999 (+)NCBIpanpan1.1PanPan1.1panPan2
MTURN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11442,890,343 - 42,928,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1442,899,944 - 42,930,117 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1442,333,147 - 42,362,237 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01442,843,199 - 42,872,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1442,843,239 - 42,872,546 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11442,959,136 - 42,987,937 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01442,637,616 - 42,666,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01442,996,504 - 43,025,394 (+)NCBIUU_Cfam_GSD_1.0
Mturn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511887,202,674 - 87,230,242 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364786,422,724 - 6,436,743 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364786,422,151 - 6,438,782 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTURN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,771,454 - 42,802,093 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11842,767,452 - 42,802,109 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21847,154,964 - 47,185,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTURN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12128,216,742 - 28,246,518 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2128,219,327 - 28,246,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604276,444,217 - 76,473,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mturn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624739626,141 - 650,645 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624739626,141 - 649,791 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mturn
833 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:378
Count of miRNA genes:266
Interacting mature miRNAs:315
Transcripts:ENSMUST00000046276
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
14696807Rbcn2_mrod bipolar cell number 2 (mouse)65118698056186985Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse

Markers in Region
BE457609  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38654,699,801 - 54,699,947UniSTSGRCm38
MGSCv37654,649,795 - 54,649,941UniSTSGRCm37
Celera655,228,695 - 55,228,841UniSTS
Cytogenetic Map6B3UniSTS
Whitehead/MRC_RH6538.31UniSTS
AI448550  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38654,703,539 - 54,703,693UniSTSGRCm38
MGSCv37654,653,533 - 54,653,687UniSTSGRCm37
Celera655,232,433 - 55,232,587UniSTS
Cytogenetic Map6B3UniSTS
Whitehead/MRC_RH6540.76UniSTS
UniSTS:235449  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38654,701,089 - 54,701,422UniSTSGRCm38
MGSCv37654,651,083 - 54,651,416UniSTSGRCm37
Celera655,229,983 - 55,230,316UniSTS
Cytogenetic Map6B3UniSTS
UniSTS:235451  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38654,703,539 - 54,703,761UniSTSGRCm38
MGSCv37654,653,533 - 54,653,755UniSTSGRCm37
Celera655,232,433 - 55,232,655UniSTS
Cytogenetic Map6B3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000185518
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl654,658,787 - 54,666,505 (+)Ensembl
GRCm38.p6 Ensembl654,681,802 - 54,689,520 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187701   ⟹   ENSMUSP00000140358
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl654,658,739 - 54,678,126 (+)Ensembl
GRCm38.p6 Ensembl654,681,754 - 54,701,141 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190641   ⟹   ENSMUSP00000140586
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl654,658,609 - 54,680,836 (+)Ensembl
GRCm38.p6 Ensembl654,681,624 - 54,703,851 (+)Ensembl
RefSeq Acc Id: NM_001289740   ⟹   NP_001276669
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39654,658,609 - 54,680,840 (+)NCBI
GRCm38654,681,624 - 54,703,855 (+)NCBI
Celera655,210,526 - 55,232,749 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289741   ⟹   NP_001276670
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39654,658,609 - 54,680,840 (+)NCBI
GRCm38654,681,624 - 54,703,855 (+)NCBI
Celera655,210,526 - 55,232,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241447   ⟹   XP_011239749
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39654,658,609 - 54,676,631 (+)NCBI
GRCm38654,681,624 - 54,699,638 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001276669   ⟸   NM_001289740
- Peptide Label: isoform a
- UniProtKB: Q8CGA4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276670   ⟸   NM_001289741
- Peptide Label: isoform b
- UniProtKB: A0A087WQV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239749   ⟸   XM_011241447
- Peptide Label: isoform X1
- UniProtKB: A0A087WQV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000140586   ⟸   ENSMUST00000190641
RefSeq Acc Id: ENSMUSP00000140358   ⟸   ENSMUST00000187701

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CGA4-F1-model_v2 AlphaFold Q8CGA4 1-131 view protein structure

Promoters
RGD ID:6838715
Promoter ID:MM_KWN:46095
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Kidney,   Lung
Transcripts:ENSMUST00000046276
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36654,631,346 - 54,631,932 (+)MPROMDB
RGD ID:6889822
Promoter ID:EPDNEW_M8345
Type:initiation region
Name:Mturn_1
Description:Mus musculus maturin, neural progenitor differentiation regulatorhomolog , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38654,681,724 - 54,681,784EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915485 AgrOrtholog
Ensembl Genes ENSMUSG00000038065 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000187701 ENTREZGENE
  ENSMUST00000187701.2 UniProtKB/TrEMBL
  ENSMUST00000190641 ENTREZGENE
  ENSMUST00000190641.7 UniProtKB/Swiss-Prot
InterPro Maturin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68235 UniProtKB/Swiss-Prot
MGD MGI:1915485 ENTREZGENE
NCBI Gene 68235 ENTREZGENE
PANTHER MATURIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR32008 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF4581 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mturn PhenoGen
UniProt A0A087WQV4 ENTREZGENE, UniProtKB/TrEMBL
  MTURN_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9CR65_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-05 Mturn  maturin, neural progenitor differentiation regulator homolog (Xenopus)  2410066E13Rik  RIKEN cDNA 2410066E13 gene  Symbol and/or name change 5135510 APPROVED