MTURN (maturin, neural progenitor differentiation regulator homolog) - Rat Genome Database

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Gene: MTURN (maturin, neural progenitor differentiation regulator homolog) Homo sapiens
Analyze
Symbol: MTURN
Name: maturin, neural progenitor differentiation regulator homolog
RGD ID: 1603878
HGNC Page HGNC:25457
Description: Involved in negative regulation of NF-kappaB transcription factor activity; positive regulation of MAPK cascade; and positive regulation of megakaryocyte differentiation. Located in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC007036.5; C7orf41; Ells1; FLJ25903; hypothetical protein LOC222166; maturin; maturin neural progenitor differentiation regulator protein homolog; maturin, neural progenitor differentiation regulator homolog (Xenopus); UPF0452 protein C7orf41
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,134,986 - 30,162,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,134,986 - 30,162,765 (+)EnsemblGRCh38hg38GRCh38
GRCh37730,174,602 - 30,202,378 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,141,077 - 30,168,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera730,163,906 - 30,191,735 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,056,754 - 30,084,572 (+)NCBIHuRef
CHM1_1730,174,629 - 30,202,485 (+)NCBICHM1_1
T2T-CHM13v2.0730,272,637 - 30,300,448 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2730,224,343 - 30,252,173 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9847074   PMID:12477932   PMID:12690205   PMID:14702039   PMID:17213182   PMID:19322201   PMID:20379614   PMID:21832049   PMID:21873635   PMID:24095902   PMID:24681962   PMID:31552488  
PMID:32296183   PMID:33506033   PMID:33528492   PMID:33961781  


Genomics

Comparative Map Data
MTURN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,134,986 - 30,162,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,134,986 - 30,162,765 (+)EnsemblGRCh38hg38GRCh38
GRCh37730,174,602 - 30,202,378 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,141,077 - 30,168,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera730,163,906 - 30,191,735 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,056,754 - 30,084,572 (+)NCBIHuRef
CHM1_1730,174,629 - 30,202,485 (+)NCBICHM1_1
T2T-CHM13v2.0730,272,637 - 30,300,448 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2730,224,343 - 30,252,173 (+)NCBI
Mturn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,658,609 - 54,680,840 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,658,609 - 54,680,836 (+)EnsemblGRCm39 Ensembl
GRCm38654,681,624 - 54,703,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,681,624 - 54,703,851 (+)EnsemblGRCm38mm10GRCm38
MGSCv37654,631,766 - 54,650,400 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36654,611,350 - 54,629,984 (+)NCBIMGSCv36mm8
Celera655,210,674 - 55,229,300 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.07NCBI
Mturn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,137,825 - 85,158,790 (+)NCBIGRCr8
mRatBN7.2483,807,528 - 83,828,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,807,579 - 83,824,950 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,028,677 - 89,049,590 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,804,099 - 84,825,012 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,219,027 - 83,239,949 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,854,341 - 84,875,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,854,386 - 84,871,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,514,247 - 149,531,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4483,087,757 - 83,105,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera478,676,774 - 78,694,109 (+)NCBICelera
Cytogenetic Map4q24NCBI
Mturn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541031,435,282 - 31,445,861 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541031,435,282 - 31,450,450 (+)NCBIChiLan1.0ChiLan1.0
MTURN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2634,955,350 - 34,983,213 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1783,280,078 - 83,307,941 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0730,766,592 - 30,794,436 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1730,884,473 - 30,909,999 (+)NCBIpanpan1.1PanPan1.1panPan2
MTURN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11442,890,343 - 42,928,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1442,899,944 - 42,930,117 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1442,333,147 - 42,362,237 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01442,843,199 - 42,872,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1442,843,239 - 42,872,546 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11442,959,136 - 42,987,937 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01442,637,616 - 42,666,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01442,996,504 - 43,025,394 (+)NCBIUU_Cfam_GSD_1.0
Mturn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511887,202,674 - 87,230,242 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364786,422,724 - 6,436,743 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364786,422,151 - 6,438,782 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTURN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,771,454 - 42,802,093 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11842,767,452 - 42,802,109 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21847,154,964 - 47,185,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTURN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12128,216,742 - 28,246,518 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2128,219,327 - 28,246,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604276,444,217 - 76,473,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mturn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624739626,141 - 650,645 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624739626,141 - 649,791 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MTURN
5 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7p22.3-14.1(chr7:54185-41875885)x3 copy number gain See cases [RCV000051159] Chr7:54185..41875885 [GRCh38]
Chr7:54185..41915483 [GRCh37]
Chr7:149268..41882008 [NCBI36]
Chr7:7p22.3-14.1		 pathogenic
GRCh38/hg38 7p15.2-14.3(chr7:25511691-30421133)x1 copy number loss See cases [RCV000052310] Chr7:25511691..30421133 [GRCh38]
Chr7:25551310..30460749 [GRCh37]
Chr7:25517835..30427274 [NCBI36]
Chr7:7p15.2-14.3		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p22.3-14.2(chr7:54185-37089712)x3 copy number gain See cases [RCV000053530] Chr7:54185..37089712 [GRCh38]
Chr7:54185..37129317 [GRCh37]
Chr7:149268..37095842 [NCBI36]
Chr7:7p22.3-14.2		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p21.1-14.3(chr7:20561456-32005143)x1 copy number loss See cases [RCV000136775] Chr7:20561456..32005143 [GRCh38]
Chr7:20601079..32044755 [GRCh37]
Chr7:20567604..32011280 [NCBI36]
Chr7:7p21.1-14.3		 pathogenic
GRCh37/hg19 7p15.3-14.3(chr7:22935369-32621975)x1 copy number loss See cases [RCV000240125] Chr7:22935369..32621975 [GRCh37]
Chr7:7p15.3-14.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p21.3-14.2(chr7:11562624-36395416)x3 copy number gain See cases [RCV000446478] Chr7:11562624..36395416 [GRCh37]
Chr7:7p21.3-14.2		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p21.3-12.1(chr7:11048840-52863626)x3 copy number gain See cases [RCV000512091] Chr7:11048840..52863626 [GRCh37]
Chr7:7p21.3-12.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p14.3(chr7:29751912-30452918)x3 copy number gain See cases [RCV000511864] Chr7:29751912..30452918 [GRCh37]
Chr7:7p14.3		 uncertain significance
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_152793.3(MTURN):c.275C>A (p.Ser92Tyr) single nucleotide variant not specified [RCV004315142] Chr7:30146289 [GRCh38]
Chr7:30185905 [GRCh37]
Chr7:7p14.3		 uncertain significance
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Childhood apraxia of speech [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NC_000007.13:g.23236782_30690453del7453672 deletion Silver Russell Syndrome-related disorder [RCV000785664] Chr7:23236782..30690453 [GRCh37]
Chr7:7p15.3-14.3		 pathogenic
GRCh37/hg19 7p15.3-14.3(chr7:23877135-33139446)x1 copy number loss not provided [RCV001005924] Chr7:23877135..33139446 [GRCh37]
Chr7:7p15.3-14.3		 pathogenic
GRCh37/hg19 7p15.1-14.3(chr7:28487175-32037495)x3 copy number gain not provided [RCV001005926] Chr7:28487175..32037495 [GRCh37]
Chr7:7p15.1-14.3		 likely pathogenic
GRCh37/hg19 7p14.3(chr7:29758030-31318843)x3 copy number gain not provided [RCV001258937] Chr7:29758030..31318843 [GRCh37]
Chr7:7p14.3		 likely pathogenic
GRCh37/hg19 7p15.2-14.1(chr7:27507832-39072473) copy number gain not specified [RCV002053677] Chr7:27507832..39072473 [GRCh37]
Chr7:7p15.2-14.1		 likely pathogenic
GRCh37/hg19 7p21.3-14.2(chr7:10745750-35305167) copy number gain not specified [RCV002053668] Chr7:10745750..35305167 [GRCh37]
Chr7:7p21.3-14.2		 likely pathogenic
NC_000007.13:g.(?_30054351)_(31018859_?)dup duplication Ehlers-Danlos syndrome, kyphoscoliotic type, 2 [RCV001911803] Chr7:30054351..31018859 [GRCh37]
Chr7:7p14.3		 uncertain significance
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p15.3-14.3(chr7:25451740-33864069) copy number loss Cyclical vomiting syndrome [RCV002280775] Chr7:25451740..33864069 [GRCh37]
Chr7:7p15.3-14.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
GRCh37/hg19 7p15.2-14.3(chr7:27133786-34466477)x1 copy number loss not provided [RCV002475752] Chr7:27133786..34466477 [GRCh37]
Chr7:7p15.2-14.3		 pathogenic
NM_152793.3(MTURN):c.82G>A (p.Glu28Lys) single nucleotide variant not specified [RCV004114353] Chr7:30135218 [GRCh38]
Chr7:30174834 [GRCh37]
Chr7:7p14.3		 uncertain significance
GRCh37/hg19 7p14.3(chr7:28940557-31806164)x3 copy number gain not specified [RCV003986729] Chr7:28940557..31806164 [GRCh37]
Chr7:7p14.3		 uncertain significance
GRCh37/hg19 7p21.1-14.3(chr7:17736012-30663423)x1 copy number loss not specified [RCV003986712] Chr7:17736012..30663423 [GRCh37]
Chr7:7p21.1-14.3		 pathogenic
NM_152793.3(MTURN):c.340G>A (p.Val114Met) single nucleotide variant not specified [RCV004512896] Chr7:30157492 [GRCh38]
Chr7:30197108 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_152793.3(MTURN):c.143A>G (p.Asn48Ser) single nucleotide variant not specified [RCV004512887] Chr7:30135279 [GRCh38]
Chr7:30174895 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_152793.3(MTURN):c.90G>T (p.Arg30Ser) single nucleotide variant not specified [RCV004638563] Chr7:30135226 [GRCh38]
Chr7:30174842 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_152793.3(MTURN):c.313G>A (p.Asp105Asn) single nucleotide variant not specified [RCV004646835] Chr7:30157465 [GRCh38]
Chr7:30197081 [GRCh37]
Chr7:7p14.3		 uncertain significance
NC_000007.13:g.(?_30054351)_(30963244_?)del deletion Charcot-Marie-Tooth disease type 2 [RCV004583590] Chr7:30054351..30963244 [GRCh37]
Chr7:7p14.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5193
Count of miRNA genes:1108
Interacting mature miRNAs:1380
Transcripts:ENST00000324453, ENST00000324489, ENST00000409688, ENST00000415604, ENST00000434060, ENST00000455738
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407154258GWAS803234_Hgut microbiome measurement QTL GWAS803234 (human)0.000001gut microbiome measurement73013722830137229Human
406979861GWAS628837_Hdental caries QTL GWAS628837 (human)0.0000007dental caries73014918830149189Human
2289453BW297_HBody weight QTL 297 (human)3.83Body weightbody mass index72334946449349464Human
407159947GWAS808923_Hgut microbiome measurement QTL GWAS808923 (human)0.000003gut microbiome measurement73013722830137229Human
407247321GWAS896297_Hcomplement factor H-related protein 3 measurement QTL GWAS896297 (human)0.000003complement factor H-related protein 3 measurement73014308830143089Human

Markers in Region
STS-H98629  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,198,852 - 30,199,009UniSTSGRCh37
Build 36730,165,377 - 30,165,534RGDNCBI36
Celera730,188,206 - 30,188,363RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,081,043 - 30,081,200UniSTS
CRA_TCAGchr7v2730,248,644 - 30,248,801UniSTS
GeneMap99-GB4 RH Map7133.57UniSTS
RH45883  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,197,914 - 30,198,036UniSTSGRCh37
Build 36730,164,439 - 30,164,561RGDNCBI36
Celera730,187,268 - 30,187,390RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,080,105 - 30,080,227UniSTS
CRA_TCAGchr7v2730,247,706 - 30,247,828UniSTS
GeneMap99-GB4 RH Map7133.57UniSTS
SHGC-53497  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,197,779 - 30,197,998UniSTSGRCh37
Build 36730,164,304 - 30,164,523RGDNCBI36
Celera730,187,133 - 30,187,352RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,079,970 - 30,080,189UniSTS
CRA_TCAGchr7v2730,247,571 - 30,247,790UniSTS
TNG Radiation Hybrid Map714355.0UniSTS
RH28602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,200,163 - 30,200,245UniSTSGRCh37
Build 36730,166,688 - 30,166,770RGDNCBI36
Celera730,189,517 - 30,189,599RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,082,354 - 30,082,436UniSTS
CRA_TCAGchr7v2730,249,955 - 30,250,037UniSTS
RH13728  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,185,445 - 30,185,643UniSTSGRCh37
Build 36730,151,970 - 30,152,168RGDNCBI36
Celera730,174,799 - 30,174,997RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,067,636 - 30,067,834UniSTS
CRA_TCAGchr7v2730,235,237 - 30,235,435UniSTS
G63258  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,182,483 - 30,182,830UniSTSGRCh37
Build 36730,149,008 - 30,149,355RGDNCBI36
Celera730,171,838 - 30,172,185RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,064,669 - 30,065,016UniSTS
CRA_TCAGchr7v2730,232,275 - 30,232,622UniSTS
TNG Radiation Hybrid Map714321.0UniSTS
SHGC-31928  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,202,230 - 30,202,379UniSTSGRCh37
Build 36730,168,755 - 30,168,904RGDNCBI36
Celera730,191,584 - 30,191,733RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,084,421 - 30,084,570UniSTS
CRA_TCAGchr7v2730,252,022 - 30,252,171UniSTS
TNG Radiation Hybrid Map714355.0UniSTS
Stanford-G3 RH Map71066.0UniSTS
Whitehead-RH Map798.2UniSTS
NCBI RH Map7457.4UniSTS
GeneMap99-G3 RH Map71066.0UniSTS
SHGC-56006  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,202,058 - 30,202,332UniSTSGRCh37
Build 36730,168,583 - 30,168,857RGDNCBI36
Celera730,191,412 - 30,191,686RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,084,249 - 30,084,523UniSTS
CRA_TCAGchr7v2730,251,850 - 30,252,124UniSTS
GeneMap99-GB4 RH Map7151.92UniSTS
Whitehead-RH Map789.5UniSTS
RH45752  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37730,201,736 - 30,201,924UniSTSGRCh37
Build 36730,168,261 - 30,168,449RGDNCBI36
Celera730,191,090 - 30,191,278RGD
Cytogenetic Map7p14.3UniSTS
HuRef730,083,927 - 30,084,115UniSTS
CRA_TCAGchr7v2730,251,528 - 30,251,716UniSTS
GeneMap99-GB4 RH Map7132.66UniSTS
NCBI RH Map7457.8UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2434 2788 2249 4970 1726 2351 4 623 1947 465 2268 7293 6463 52 3733 852 1743 1616 175 1

Sequence


Ensembl Acc Id: ENST00000324453   ⟹   ENSP00000324204
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl730,134,986 - 30,162,762 (+)Ensembl
Ensembl Acc Id: ENST00000324489   ⟹   ENSP00000324755
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl730,145,801 - 30,162,765 (+)Ensembl
Ensembl Acc Id: ENST00000409688   ⟹   ENSP00000386490
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl730,134,988 - 30,157,969 (+)Ensembl
Ensembl Acc Id: ENST00000434060   ⟹   ENSP00000415658
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl730,137,259 - 30,146,295 (+)Ensembl
RefSeq Acc Id: NM_152793   ⟹   NP_690006
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38730,134,986 - 30,162,762 (+)NCBI
GRCh37730,174,552 - 30,202,381 (+)RGD
GRCh37730,174,552 - 30,202,381 (+)NCBI
Build 36730,141,077 - 30,168,906 (+)NCBI Archive
Celera730,163,906 - 30,191,735 (+)RGD
HuRef730,056,754 - 30,084,572 (+)RGD
CHM1_1730,174,629 - 30,202,485 (+)NCBI
T2T-CHM13v2.0730,272,637 - 30,300,448 (+)NCBI
CRA_TCAGchr7v2730,224,343 - 30,252,173 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_005249652   ⟹   XP_005249709
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38730,134,986 - 30,162,762 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054357567   ⟹   XP_054213542
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0730,272,637 - 30,300,448 (+)NCBI
RefSeq Acc Id: NP_690006   ⟸   NM_152793
- UniProtKB: Q8N8M4 (UniProtKB/Swiss-Prot),   Q8N791 (UniProtKB/Swiss-Prot),   B8ZZW9 (UniProtKB/Swiss-Prot),   Q8NEX2 (UniProtKB/Swiss-Prot),   Q8N3F0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005249709   ⟸   XM_005249652
- Peptide Label: isoform X1
- UniProtKB: Q8N8M4 (UniProtKB/Swiss-Prot),   Q8N791 (UniProtKB/Swiss-Prot),   B8ZZW9 (UniProtKB/Swiss-Prot),   Q8NEX2 (UniProtKB/Swiss-Prot),   Q8N3F0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000324204   ⟸   ENST00000324453
Ensembl Acc Id: ENSP00000324755   ⟸   ENST00000324489
Ensembl Acc Id: ENSP00000386490   ⟸   ENST00000409688
Ensembl Acc Id: ENSP00000415658   ⟸   ENST00000434060
RefSeq Acc Id: XP_054213542   ⟸   XM_054357567
- Peptide Label: isoform X1
- UniProtKB: Q8NEX2 (UniProtKB/Swiss-Prot),   Q8N8M4 (UniProtKB/Swiss-Prot),   Q8N791 (UniProtKB/Swiss-Prot),   Q8N3F0 (UniProtKB/Swiss-Prot),   B8ZZW9 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N3F0-F1-model_v2 AlphaFold Q8N3F0 1-131 view protein structure

Promoters
RGD ID:7210269
Promoter ID:EPDNEW_H10880
Type:initiation region
Name:MTURN_2
Description:maturin, neural progenitor differentiation regulator homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10881  EPDNEW_H10883  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38730,134,732 - 30,134,792EPDNEW
RGD ID:7210271
Promoter ID:EPDNEW_H10881
Type:initiation region
Name:MTURN_1
Description:maturin, neural progenitor differentiation regulator homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10880  EPDNEW_H10883  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38730,134,986 - 30,135,046EPDNEW
RGD ID:6805314
Promoter ID:HG_KWN:56799
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000409688,   OTTHUMT00000250409,   UC010KVR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36730,140,791 - 30,141,392 (+)MPROMDB
RGD ID:7210275
Promoter ID:EPDNEW_H10883
Type:initiation region
Name:MTURN_3
Description:maturin, neural progenitor differentiation regulator homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10880  EPDNEW_H10881  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38730,145,845 - 30,145,905EPDNEW
RGD ID:6805128
Promoter ID:HG_KWN:56803
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour
Transcripts:OTTHUMT00000327701
Position:
Human AssemblyChrPosition (strand)Source
Build 36730,163,191 - 30,163,691 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25457 AgrOrtholog
COSMIC MTURN COSMIC
Ensembl Genes ENSG00000180354 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000324453 ENTREZGENE
  ENST00000324453.13 UniProtKB/Swiss-Prot
  ENST00000324489.5 UniProtKB/Swiss-Prot
  ENST00000409688.1 UniProtKB/Swiss-Prot
  ENST00000434060.1 UniProtKB/TrEMBL
GTEx ENSG00000180354 GTEx
HGNC ID HGNC:25457 ENTREZGENE
Human Proteome Map MTURN Human Proteome Map
InterPro Maturin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:222166 UniProtKB/Swiss-Prot
NCBI Gene 222166 ENTREZGENE
OMIM 620491 OMIM
PANTHER MATURIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR32008 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF4581 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA147358571 PharmGKB
UniProt B8ZZW9 ENTREZGENE
  C9JBT1_HUMAN UniProtKB/TrEMBL
  MTURN_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q8N791 ENTREZGENE
  Q8N8M4 ENTREZGENE
  Q8NEX2 ENTREZGENE
UniProt Secondary B8ZZW9 UniProtKB/Swiss-Prot
  Q8N791 UniProtKB/Swiss-Prot
  Q8N8M4 UniProtKB/Swiss-Prot
  Q8NEX2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-02 MTURN  maturin, neural progenitor differentiation regulator homolog    maturin, neural progenitor differentiation regulator homolog (Xenopus)  Symbol and/or name change 5135510 APPROVED
2013-10-22 MTURN  maturin, neural progenitor differentiation regulator homolog (Xenopus)  C7orf41  chromosome 7 open reading frame 41  Symbol and/or name change 5135510 APPROVED