Ptch2 (patched 2) - Rat Genome Database

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Gene: Ptch2 (patched 2) Mus musculus
Analyze
Symbol: Ptch2
Name: patched 2
RGD ID: 1615950
MGI Page MGI
Description: Predicted to enable hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Acts upstream of or within several processes, including epidermal cell fate specification; hair cycle; and positive regulation of epidermal cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and limb. Human ortholog(s) of this gene implicated in basal cell carcinoma and medulloblastoma. Orthologous to human PTCH2 (patched 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: patched homolog 2; protein patched homolog 2; ptc; ptc2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,953,253 - 116,973,298 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,953,272 - 116,973,298 (+)EnsemblGRCm39 Ensembl
GRCm384117,096,056 - 117,116,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,096,075 - 117,116,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,768,961 - 116,787,436 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,594,288 - 116,612,763 (+)NCBIMGSCv36mm8
MGSCv364114,859,487 - 114,878,450 (+)NCBIMGSCv36mm8
Celera4115,831,925 - 115,852,375 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Hedgehog signaling update. Cohen MM, Am J Med Genet A. 2010 Aug;152A(8):1875-914. doi: 10.1002/ajmg.a.32909.
2. Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. Mimeault M and Batra SK, Pharmacol Rev. 2010 Sep;62(3):497-524.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9237688   PMID:9462734   PMID:9671585   PMID:9768360   PMID:9768363   PMID:9811851   PMID:9858693   PMID:10027293   PMID:10349636   PMID:10465785   PMID:10512189   PMID:10529434  
PMID:10926756   PMID:10981962   PMID:11042159   PMID:11044393   PMID:11076861   PMID:11217851   PMID:11311154   PMID:11389830   PMID:11476582   PMID:11758785   PMID:11784021   PMID:12403705  
PMID:12438747   PMID:12466851   PMID:12477932   PMID:12533516   PMID:12615071   PMID:14610273   PMID:14681479   PMID:14724733   PMID:14973295   PMID:15563592   PMID:15668330   PMID:16141072  
PMID:16141073   PMID:16168717   PMID:16236765   PMID:16284245   PMID:16602821   PMID:16849540   PMID:16914743   PMID:16958114   PMID:17257418   PMID:17397822   PMID:17442700   PMID:17631878  
PMID:18022614   PMID:18206867   PMID:18417110   PMID:18591670   PMID:18625210   PMID:18799693   PMID:18832395   PMID:19076778   PMID:19445942   PMID:19487286   PMID:19570847   PMID:19574535  
PMID:19783740   PMID:19815519   PMID:20637749   PMID:21731673   PMID:21873635   PMID:22869526   PMID:23034632   PMID:23077214   PMID:23123965   PMID:23618354   PMID:23900540   PMID:24194600  
PMID:24318810   PMID:24492243   PMID:24990743   PMID:25085974   PMID:25224227   PMID:25422376   PMID:25448692   PMID:25458012   PMID:26057579   PMID:26238476   PMID:26697723   PMID:26834157  
PMID:26932670   PMID:27046536   PMID:27320915   PMID:27498049   PMID:27552050   PMID:27647915   PMID:28049658   PMID:28202523   PMID:28323616   PMID:28344083   PMID:28380258   PMID:28527696  
PMID:28688895   PMID:28943241   PMID:29109083   PMID:30166346   PMID:30352686   PMID:31068622   PMID:31145830   PMID:31167144   PMID:31226309   PMID:31719045   PMID:32332736   PMID:32674056  
PMID:32702291   PMID:32747435   PMID:32945847   PMID:34321999   PMID:34346313   PMID:34353359   PMID:34979374   PMID:35112129   PMID:36459481   PMID:37228654   PMID:37516749   PMID:38131461  
PMID:38355793   PMID:39012257  


Genomics

Comparative Map Data
Ptch2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,953,253 - 116,973,298 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,953,272 - 116,973,298 (+)EnsemblGRCm39 Ensembl
GRCm384117,096,056 - 117,116,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,096,075 - 117,116,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,768,961 - 116,787,436 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,594,288 - 116,612,763 (+)NCBIMGSCv36mm8
MGSCv364114,859,487 - 114,878,450 (+)NCBIMGSCv36mm8
Celera4115,831,925 - 115,852,375 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
PTCH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38144,819,845 - 44,843,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl144,819,154 - 44,843,253 (-)EnsemblGRCh38hg38GRCh38
GRCh37145,285,517 - 45,308,925 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,060,674 - 45,081,203 (-)NCBINCBI36Build 36hg18NCBI36
Celera143,568,356 - 43,591,362 (-)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef143,398,182 - 43,420,910 (-)NCBIHuRef
CHM1_1145,401,618 - 45,424,714 (-)NCBICHM1_1
T2T-CHM13v2.0144,691,074 - 44,714,486 (-)NCBIT2T-CHM13v2.0
Ptch2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,808,856 - 135,829,087 (+)NCBIGRCr8
mRatBN7.25130,571,956 - 130,592,506 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,572,312 - 130,592,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5133,196,938 - 133,216,756 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,951,546 - 134,971,365 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,973,962 - 134,993,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,962,252 - 135,983,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,962,911 - 135,983,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,757,425 - 139,776,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,408,481 - 137,429,633 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15137,410,236 - 137,433,563 (+)NCBI
Celera5129,093,838 - 129,114,695 (+)NCBICelera
Cytogenetic Map5q36NCBI
Ptch2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546413,387,844 - 13,403,991 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546413,387,844 - 13,403,991 (+)NCBIChiLan1.0ChiLan1.0
PTCH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21181,961,952 - 181,985,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11181,102,730 - 181,127,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,125,693 - 44,147,462 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1145,492,111 - 45,513,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl145,490,789 - 45,513,055 (-)Ensemblpanpan1.1panPan2
PTCH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11515,488,357 - 15,503,748 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1515,487,639 - 15,503,234 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1515,608,551 - 15,623,939 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01515,643,729 - 15,659,090 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1515,643,844 - 15,659,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11515,440,572 - 15,455,919 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01515,508,480 - 15,523,831 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01515,581,190 - 15,596,607 (+)NCBIUU_Cfam_GSD_1.0
Ptch2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505860,227,398 - 60,245,014 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,052,305 - 26,069,312 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,052,277 - 26,069,500 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTCH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6166,495,763 - 166,512,648 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16166,491,649 - 166,513,137 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26153,908,118 - 153,910,272 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTCH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12087,953,877 - 87,975,087 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2087,953,971 - 87,974,607 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603328,965,428 - 28,987,647 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptch2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624906706,492 - 726,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624906707,270 - 726,570 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptch2
1354 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2883
Count of miRNA genes:812
Interacting mature miRNAs:1061
Transcripts:ENSMUST00000030443, ENSMUST00000123226, ENSMUST00000135133, ENSMUST00000137209, ENSMUST00000144620, ENSMUST00000156989
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4110857197125893793Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488118237118557197Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
1301996Mmtg2_mmodifier of mammary tumor growth 2 (mouse)Not determined4116270979124055180Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000030443   ⟹   ENSMUSP00000030443
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,953,272 - 116,972,580 (+)Ensembl
GRCm38.p6 Ensembl4117,096,075 - 117,115,383 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,970,621 - 116,973,298 (+)Ensembl
GRCm38.p6 Ensembl4117,113,424 - 117,116,101 (+)Ensembl
Ensembl Acc Id: ENSMUST00000135133
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,967,432 - 116,968,285 (+)Ensembl
GRCm38.p6 Ensembl4117,110,235 - 117,111,088 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137209   ⟹   ENSMUSP00000114461
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,962,435 - 116,965,711 (+)Ensembl
GRCm38.p6 Ensembl4117,105,238 - 117,108,514 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144620   ⟹   ENSMUSP00000122548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,953,293 - 116,972,580 (+)Ensembl
GRCm38.p6 Ensembl4117,096,096 - 117,115,383 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156989
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,962,117 - 116,963,510 (+)Ensembl
GRCm38.p6 Ensembl4117,104,920 - 117,106,313 (+)Ensembl
RefSeq Acc Id: NM_001312903   ⟹   NP_001299832
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,953,253 - 116,973,298 (+)NCBI
GRCm384117,096,056 - 117,116,101 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008958   ⟹   NP_032984
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,953,253 - 116,973,298 (+)NCBI
GRCm384117,096,056 - 117,116,101 (+)NCBI
MGSCv374116,768,961 - 116,787,436 (+)RGD
Celera4115,831,925 - 115,852,375 (+)RGD
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001299832 (Get FASTA)   NCBI Sequence Viewer  
  NP_032984 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA24691 (Get FASTA)   NCBI Sequence Viewer  
  CAC88120 (Get FASTA)   NCBI Sequence Viewer  
  EDL30571 (Get FASTA)   NCBI Sequence Viewer  
  EDL30572 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000030443
  ENSMUSP00000030443.6
GenBank Protein O35595 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032984   ⟸   NM_008958
- Peptide Label: isoform 1
- UniProtKB: A2AE82 (UniProtKB/Swiss-Prot),   Q546T0 (UniProtKB/Swiss-Prot),   O35595 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001299832   ⟸   NM_001312903
- Peptide Label: isoform 2
- Sequence:
Ensembl Acc Id: ENSMUSP00000122548   ⟸   ENSMUST00000144620
Ensembl Acc Id: ENSMUSP00000114461   ⟸   ENSMUST00000137209
Ensembl Acc Id: ENSMUSP00000030443   ⟸   ENSMUST00000030443
Protein Domains
SSD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35595-F1-model_v2 AlphaFold O35595 1-1182 view protein structure

Promoters
RGD ID:6836000
Promoter ID:MM_KWN:39215
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6,   ES_Cell
Transcripts:OTTMUST00000023049,   OTTMUST00000023050
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,767,781 - 116,768,752 (+)MPROMDB
RGD ID:6836001
Promoter ID:MM_KWN:39217
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000023054
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,781,926 - 116,782,426 (+)MPROMDB
RGD ID:6884348
Promoter ID:EPDNEW_M5625
Type:initiation region
Name:Ptch2_1
Description:Mus musculus patched 2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384117,096,059 - 117,096,119EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1095405 AgrOrtholog
Ensembl Genes ENSMUSG00000028681 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030443 ENTREZGENE
  ENSMUST00000030443.12 UniProtKB/Swiss-Prot
Gene3D-CATH Multidrug efflux transporter AcrB transmembrane domain UniProtKB/Swiss-Prot
InterPro HMGCR/SNAP/NPC1-like_SSD UniProtKB/Swiss-Prot
  Ptc/Disp UniProtKB/Swiss-Prot
  SSD UniProtKB/Swiss-Prot
  TM_rcpt_patched UniProtKB/Swiss-Prot
KEGG Report mmu:19207 UniProtKB/Swiss-Prot
MGD MGI:1095405 ENTREZGENE
NCBI Gene 19207 ENTREZGENE
PANTHER PROTEIN PATCHED UniProtKB/Swiss-Prot
  PROTEIN PATCHED HOMOLOG 2 UniProtKB/Swiss-Prot
Pfam Patched UniProtKB/Swiss-Prot
  Sterol-sensing UniProtKB/Swiss-Prot
PhenoGen Ptch2 PhenoGen
PROSITE SSD UniProtKB/Swiss-Prot
Superfamily-SCOP Multidrug efflux transporter AcrB transmembrane domain UniProtKB/Swiss-Prot
UniProt A2AE82 ENTREZGENE
  D6RG83_MOUSE UniProtKB/TrEMBL
  F6XYY1_MOUSE UniProtKB/TrEMBL
  O35595 ENTREZGENE, UniProtKB/Swiss-Prot
  Q546T0 ENTREZGENE
UniProt Secondary A2AE82 UniProtKB/Swiss-Prot
  Q546T0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Ptch2  patched 2    patched homolog 2  Symbol and/or name change 5135510 APPROVED