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Gene: Yju2 (YJU2 splicing factor) Rattus norvegicus

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Symbol:

Yju2

Name:

YJU2 splicing factor

RGD ID:

1589601

Description:

Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to be part of U2-type catalytic step 1 spliceosome. Orthologous to human YJU2 (YJU2 splicing factor homolog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; paracetamol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Ccdc94; coiled-coil domain containing 94; coiled-coil domain-containing protein 94; LOC501285; MGC156684; similar to CG8435-PA; splicing factor YJU2; YJU2 splicing factor homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	YJU2 (YJU2 splicing factor homolog)	RGD	RGD
Mus musculus (house mouse):	Yju2 (YJU2 splicing factor)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Yju2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	YJU2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	YJU2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Yju2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	YJU2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	YJU2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Yju2 (YJU2 splicing factor homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Yju2 (YJU2 splicing factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	YJU2 (YJU2 splicing factor homolog)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F37C12.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8435	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YJU2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	yju2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	yju2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	876,790 - 886,687 (+)	NCBI		GRCr8
mRatBN7.2	9	789,603 - 799,505 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	789,606 - 799,496 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	1,236,798 - 1,246,612 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	6,583,974 - 6,593,798 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	5,541,835 - 5,551,650 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	11,098,914 - 11,108,806 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	11,098,924 - 11,108,741 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	10,084,078 - 10,093,964 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	7,706,956 - 7,716,779 (-)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Yju2	Rat	amenorrhea		ISO	YJU2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Primary amenorrhea	ClinVar	PMID:21681106

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Yju2	Rat	1,2-dimethylhydrazine	increases expression	ISO	Yju2 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of YJU2 mRNA	CTD	PMID:22206623
Yju2	Rat	2,2',4,4'-Tetrabromodiphenyl ether	increases expression	EXP		6480464	2 more ...	CTD	PMID:27291303
Yju2	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	Yju2 (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in decreased expression of YJU2 mRNA	CTD	PMID:21354282
Yju2	Rat	antirheumatic drug	decreases expression	ISO	YJU2 (Homo sapiens)	6480464	Antirheumatic Agents results in decreased expression of YJU2 mRNA	CTD	PMID:24449571
Yju2	Rat	arsane	affects methylation	ISO	YJU2 (Homo sapiens)	6480464	Arsenic affects the methylation of YJU2 gene	CTD	PMID:25304211
Yju2	Rat	arsenic atom	affects methylation	ISO	YJU2 (Homo sapiens)	6480464	Arsenic affects the methylation of YJU2 gene	CTD	PMID:25304211
Yju2	Rat	arsenite(3-)	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	arsenite promotes the reaction [G3BP1 protein binds to YJU2 mRNA]	CTD	PMID:32406909
Yju2	Rat	atrazine	increases expression	ISO	YJU2 (Homo sapiens)	6480464	Atrazine results in increased expression of YJU2 mRNA	CTD	PMID:22378314
Yju2	Rat	bis(2-chloroethyl) sulfide	increases phosphorylation	ISO	YJU2 (Homo sapiens)	6480464	Mustard Gas results in increased phosphorylation of YJU2 protein	CTD	PMID:19845377
Yju2	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of YJU2 mRNA	CTD	PMID:30816183 and PMID:32528016
Yju2	Rat	bisphenol A	decreases methylation	ISO	YJU2 (Homo sapiens)	6480464	bisphenol A results in decreased methylation of YJU2 gene	CTD	PMID:31601247
Yju2	Rat	bisphenol A	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of YJU2 gene	CTD	PMID:31601247
Yju2	Rat	cadmium atom	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of YJU2 mRNA	CTD	PMID:35301059
Yju2	Rat	cadmium dichloride	decreases expression	ISO	Yju2 (Mus musculus)	6480464	Cadmium Chloride results in decreased expression of YJU2 mRNA	CTD	PMID:20883709
Yju2	Rat	cadmium dichloride	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of YJU2 mRNA	CTD	PMID:35301059
Yju2	Rat	cadmium dichloride	increases expression	ISO	YJU2 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of YJU2 mRNA	CTD	PMID:38568856
Yju2	Rat	copper atom	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA	CTD	PMID:24690739
Yju2	Rat	copper(0)	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA	CTD	PMID:24690739
Yju2	Rat	copper(II) sulfate	increases expression	ISO	YJU2 (Homo sapiens)	6480464	Copper Sulfate results in increased expression of YJU2 mRNA	CTD	PMID:19549813
Yju2	Rat	coumarin	decreases phosphorylation	ISO	YJU2 (Homo sapiens)	6480464	coumarin results in decreased phosphorylation of YJU2 protein	CTD	PMID:35688186
Yju2	Rat	Dibutyl phosphate	affects expression	ISO	YJU2 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of YJU2 mRNA	CTD	PMID:37042841
Yju2	Rat	disulfiram	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA	CTD	PMID:24690739
Yju2	Rat	doxorubicin	decreases expression	ISO	YJU2 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of YJU2 mRNA	CTD	PMID:29803840
Yju2	Rat	ethanol	affects expression	ISO	Yju2 (Mus musculus)	6480464	Ethanol affects the expression of YJU2 mRNA	CTD	PMID:30319688
Yju2	Rat	fulvestrant	multiple interactions	ISO	YJU2 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of YJU2 gene	CTD	PMID:31601247
Yju2	Rat	ivermectin	decreases expression	ISO	YJU2 (Homo sapiens)	6480464	Ivermectin results in decreased expression of YJU2 protein	CTD	PMID:32959892
Yju2	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of YJU2 mRNA	CTD	PMID:33387578
Yju2	Rat	potassium dichromate	decreases expression	ISO	Yju2 (Mus musculus)	6480464	Potassium Dichromate results in decreased expression of YJU2 mRNA	CTD	PMID:23608068
Yju2	Rat	sodium arsenite	decreases expression	ISO	Yju2 (Mus musculus)	6480464	sodium arsenite results in decreased expression of YJU2 mRNA	CTD	PMID:20883709
Yju2	Rat	sunitinib	increases expression	ISO	YJU2 (Homo sapiens)	6480464	Sunitinib results in increased expression of YJU2 mRNA	CTD	PMID:31533062
Yju2	Rat	tamoxifen	increases expression	ISO	Yju2 (Mus musculus)	6480464	Tamoxifen results in increased expression of YJU2 mRNA	CTD	PMID:17555576
Yju2	Rat	thiram	increases expression	ISO	YJU2 (Homo sapiens)	6480464	Thiram results in increased expression of YJU2 mRNA	CTD	PMID:38568856
Yju2	Rat	titanium dioxide	decreases methylation	ISO	Yju2 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of CCDC94 gene and titanium dioxide results in decreased methylation of CCDC94 promoter	CTD	PMID:35295148
Yju2	Rat	valproic acid	affects expression	ISO	YJU2 (Homo sapiens)	6480464	Valproic Acid affects the expression of YJU2 mRNA	CTD	PMID:25979313
Yju2	Rat	valproic acid	decreases expression	ISO	Yju2 (Mus musculus)	6480464	Valproic Acid results in decreased expression of YJU2 mRNA	CTD	PMID:21427059

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Yju2	Rat	generation of catalytic spliceosome for first transesterification step	involved_in	IEA	UniRule:UR001137104	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Yju2	Rat	mRNA processing	involved_in	IEA	UniProtKB-KW:KW-0507	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Yju2	Rat	mRNA splicing, via spliceosome	involved_in	IEA	InterPro:IPR007590 and InterPro:IPR043701	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Yju2	Rat	RNA splicing	involved_in	IBA	PANTHER:PTN000251377 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Yju2	Rat	RNA splicing	involved_in	IEA	UniProtKB-KW:KW-0508	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Yju2	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Yju2	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Yju2	Rat	spliceosomal complex	part_of	IEA	UniProtKB-KW:KW-0747	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Yju2	Rat	U2-type catalytic step 1 spliceosome	part_of	ISO	YJU2 (Homo sapiens)	1624291	PMID:29301961	RGD	PMID:29301961
Yju2	Rat	U2-type catalytic step 1 spliceosome	part_of	IEA	UniRule:UR001137104	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Yju2	Rat	U2-type catalytic step 1 spliceosome	part_of	IBA	PANTHER:PTN000251428 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Yju2	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Yju2	Rat	protein binding	enables	ISO	YJU2 (Homo sapiens)	1624291	UniProtKB:A0A384NQ31 more ...	RGD	PMID:25416956 more ...

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932	PMID:29301961

Yju2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	876,790 - 886,687 (+)	NCBI		GRCr8
mRatBN7.2	9	789,603 - 799,505 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	789,606 - 799,496 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	1,236,798 - 1,246,612 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	6,583,974 - 6,593,798 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	5,541,835 - 5,551,650 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	11,098,914 - 11,108,806 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	11,098,924 - 11,108,741 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	10,084,078 - 10,093,964 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	7,706,956 - 7,716,779 (-)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

YJU2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	4,247,080 - 4,269,088 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	4,247,080 - 4,269,088 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	4,247,077 - 4,269,085 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	4,198,111 - 4,220,085 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	4,186,494 - 4,208,470 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	4,010,325 - 4,032,247 (+)	NCBI		HuRef
CHM1_1	19	4,246,732 - 4,268,702 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	4,229,720 - 4,252,363 (+)	NCBI		T2T-CHM13v2.0

Yju2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	56,266,187 - 56,274,951 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	56,266,099 - 56,275,285 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	55,959,187 - 55,967,951 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	55,959,099 - 55,968,285 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	56,098,610 - 56,107,374 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	55,552,467 - 55,561,574 (+)	NCBI		MGSCv36	mm8
Celera	17	59,377,714 - 59,386,478 (+)	NCBI		Celera
Cytogenetic Map	17	D	NCBI
cM Map	17	29.08	NCBI

Yju2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	4,592,523 - 4,606,005 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	4,591,242 - 4,605,403 (-)	NCBI	ChiLan1.0	ChiLan1.0

YJU2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	8,644,495 - 8,666,464 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	7,874,484 - 7,896,519 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	3,270,432 - 3,292,457 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	4,217,448 - 4,239,684 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	4,217,457 - 4,239,684 (+)	Ensembl	panpan1.1		panPan2

YJU2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	55,367,512 - 55,380,755 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	55,368,480 - 55,380,679 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	55,095,555 - 55,108,798 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	56,026,737 - 56,039,990 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	56,026,667 - 56,039,942 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	55,086,676 - 55,099,906 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	55,567,887 - 55,581,120 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	55,766,561 - 55,779,809 (-)	NCBI		UU_Cfam_GSD_1.0

Yju2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	215,395,972 - 215,407,869 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	2,427,126 - 2,440,939 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	2,426,786 - 2,438,811 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

YJU2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	74,509,739 - 74,528,300 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	74,507,830 - 74,528,333 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	75,001,394 - 75,022,973 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

YJU2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	3,995,769 - 4,013,288 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666081	4,200,131 - 4,223,532 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Yju2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	5,381,617 - 5,397,782 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	5,381,387 - 5,397,893 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Yju2
17 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	503
Count of miRNA genes:	264
Interacting mature miRNAs:	311
Transcripts:	ENSRNOT00000072357
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	14209783	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat

RH134940

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	799,190 - 799,410 (-)	MAPPER	mRatBN7.2
Rnor_6.0	9	11,099,009 - 11,099,228	NCBI	Rnor6.0
Rnor_5.0	9	10,084,173 - 10,084,392	UniSTS	Rnor5.0
Celera	9	7,707,047 - 7,707,266	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001109673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC129098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC169032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072357 ⟹ ENSRNOP00000067468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	789,606 - 799,496 (+)	Ensembl
Rnor_6.0 Ensembl	9	11,098,924 - 11,108,741 (-)	Ensembl

RefSeq Acc Id:

NM_001109673 ⟹ NP_001103143

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	876,864 - 886,687 (+)	NCBI
mRatBN7.2	9	789,677 - 799,501 (+)	NCBI
Rnor_6.0	9	11,098,918 - 11,108,741 (-)	NCBI
Rnor_5.0	9	10,084,078 - 10,093,964 (-)	NCBI
Celera	9	7,706,956 - 7,716,779 (-)	RGD

Sequence:

show sequence

ATTTCTTCTCTTGTTCGTTGAACAGGAAGCGAAGATGTCGGAACGGAAAGTTTTAAACAAATACTACCCACCTGACTTTGACCCATCGAAGATCCCGAAACTCAAGTTACCCAAGGACCGGCAGTACG
TGGTGCGGCTGATGGCCCCATTCAACATGAGGTGTAAGACATGTGGAGAATACATCTACAAGGGGAAGAAGTTCAATGCACGAAAGGAAACAGTCCAGAATGAGGCATACCTGGGCTTGCCAATCTTC
CGTTTCTATATCAAGTGCACACGCTGCTTGGCCGAGATCACCTTTAAGACAGACCCAGAGAACACAGACTACACCATGGAGCATGGGGCCACGCGCAACTTCCAGGCTGAGAAGCTTCTGGAGGAGGA
GGAAAAGCGCATGCAGAAGGAGCGTGAGGATGAGGAGCTGAACAACCCCATGAAGGTCCTAGAGAACCGTACAAAGGACTCTAAGCTGGAGATGGAAGTGCTAGAGAACCTACAAGAGCTAAAAGACC
TGAACCAGCGGCAGGCCCACGTGGACTTTGAGGCCATGCTGCTACAACACCGCCTATCTCAGGAGCAGTGGCAACAGCAGCAGGAAGAGGAAGACGAGCGTGAGACAGTGGCCTTGCTGGAGGAGGCT
CGTTATCGAAGGCTTCTGGATGACTCTGACTCAGAGGATGAGGCTCCACCTTCCCAACCACAGGCAGCTGCAAGACCCAACCCCACAGCCATTCTTGATGAGGTACCAAAGACCAAGAGGAAGGCAGA
GGGCCTGTGCAGGAAAGCCCAGTTGGCAGGCTTGGTTATACCAAAGAAGGCAAAGACGGAAGCCAACCGGGTTTCAGAGCAGGTCCGGGTGCCCACCACTGGTGCCCCCGAGAGCAGGAAGGTGGCCA
ACCCTGCACCCCAGACACCTGGTGCCTCCTCCCTGAGCCAGCTCGGTGCATATGGGGACAGTGAGGACAGTGACAGCTGAGCATCAGTGATGCTCACCGTGGCATCATAGACCAAGAAATGAAGATGG
TATCAAGCAAACACCTTCAGCCAAGCCTCAGGACCATTCTACCATGGGTGGGCAGGGTGTGGAGAAGCACTGTCCCCAGGCACCCCAGGACAGACAGCCTGGTCCAGTCCTTCAGTCCTTGATGTGTG
AAGCCTGTTAACTGATCCCTTCCTGCAGCAGATGTGAACACTGTCTGACATAGGATGGGGGCAGGGACCCTGGGCAGCATCTGCCAACCATACGCAAGGCCTGGGGCTCCACCCACATGCAACACAGT
AGTACTGTAAAAACAAGAAGAATAGAAAATCAGCTGAAGCTTTTGGACCGGAAGACAGTGGAGACAAAATGAACAGGACTCCAAAGGACTTGTCCAGGATTCCACAGTGACTCAGAAGCAAGCCCAGT
GAGTCAATGTCCTGACCAATCTGTGGCCCACTGTGTGCCAGTTCACGACATTCGGTCTCCAGTGTGGAGGAAAGTGACCCATCCCAGTAAATGCAGCACCCAGGAGCTGGACATAGAATCTGAGTACA
AAGCCATCCTTGGCTATAAGGCTTTCGTGGCACAACCCAGGCCTGTCTAAACCTCGGAAGGCTTGTTTGCTACTTTCAAACAAGAACACCAAAGTCTGGTTGCAACAGGAACTTCACAGTCGAAAAAG
CTTAAAATGTAGCCTGGGCCTGGGCTTGTCCACCTCAATACAGCAAACTTTTGACAGCCCCTCACTGTGGAATGACACCACAGACATTTCACACCTAATATAAAGCTGGTGGGAGCAACACCACTGTA
CCCTCAGAGACTGGTTCTCCCTCAAAACTGTCACTGCTAAACAGGTAAGAGTGTTCGCAGCAGGGTTGGGGGAGGGGTCAAGCAAATGTCATTCCACAGCCTGGAAATCCTAATCTTCCTTTAATAAG
AGTTAACCTCCTCCTAAGGTTTTCCTCATTGTATACTAAAAGCAAGTGTTCGTTACCTCGGTGAAATCTGCCGGAACTAGCATGTATTTGCCACTGGAACAAACAATGGGTTTTTCTTAATTAATAAA
ACATTAACATGAAAATGTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006244336 ⟹ XP_006244398

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	876,790 - 886,687 (+)	NCBI
mRatBN7.2	9	789,603 - 799,505 (+)	NCBI
Rnor_6.0	9	11,098,914 - 11,108,806 (-)	NCBI
Rnor_5.0	9	10,084,078 - 10,093,964 (-)	NCBI

Sequence:

show sequence

ACGGCTGAGGAAGTGGCGACACTGAGGCTCCTGATCCGAGAAACTCCACGAGGACTAAGAGAAC
AATTTCTTCTCTTGTTCGTTGAACAGGAAGCGAAGATGTCGGAACGGAAAGTTTTAAACAAATACTACCCACCTGACTTTGACCCATCGAAGATCCCGAAACTCAAGTTACCCAAGGACCGGCAGTAC
GTGGTGCGGCTGATGGCCCCATTCAACATGAGGTGTAAGACATGTGGAGAATACATCTACAAGGGGAAGAAGTTCAATGCACGAAAGGAAACAGTCCAGAATGAGGCATACCTGGGCTTGCCAATCTT
CCGTTTCTATATCAAGTGCACACGCTGCTTGGCCGAGATCACCTTTAAGACAGACCCAGAGAACACAGACTACACCATGGAGCATGGGGCCACGCGCAACTTCCAGGCTGAGAAGCTTCTGGAGGAGG
AGGAAAAGCGCATGCAGAAGGAGCGTGAGGATGAGGAGCTGAACAACCCCATGAAGGTCCTAGAGAACCGTACAAAGGACTCTAAGCTGGAGATGGAAGTGCTAGAGAACCTACAAGAGCTAAAAGAC
CTGAACCAGCGGCAGGCCCACGTGGACTTTGAGGCCATGCTGCTACAACACCGCCTATCTCAGGAGCAGTGGCAACAGCAGCAGGAAGAGGAAGACGAGCGTGAGACAGTGGCCTTGCTGGAGGAGGC
TCGTTATCGAAGGCTTCTGGATGACTCTGACTCAGAGGATGAGGCTCCACCTTCCCAACCACAGGCAGCTGCAAGACCCAACCCCACAGCCATTCTTGATGAGGTGCCCCCGAGAGCAGGAAGGTGGC
CAACCCTGCACCCCAGACACCTGGTGCCTCCTCCCTGAGCCAGCTCGGTGCATATGGGGACAGTGAGGACAGTGACAGCTGAGCATCAGTGATGCTCACCGTGGCATCATAGACCAAGAAATGAAGAT
GGTATCAAGCAAACACCTTCAGCCAAGCCTCAGGACCATTCTACCATGGGTGGGCAGGGTGTGGAGAAGCACTGTCCCCAGGCACCCCAGGACAGACAGCCTGGTCCAGTCCTTCAGTCCTTGATGTG
TGAAGCCTGTTAACTGATCCCTTCCTGCAGCAGATGTGAACACTGTCTGACATAGGATGGGGGCAGGGACCCTGGGCAGCATCTGCCAACCATACGCAAGGCCTGGGGCTCCACCCACATGCAACACA
GTAGTACTGTAAAAACAAGAAGAATAGAAAATCAGCTGAAGCTTTTGGACCGGAAGACAGTGGAGACAAAATGAACAGGACTCCAAAGGACTTGTCCAGGATTCCACAGTGACTCAGAAGCAAGCCCA
GTGAGTCAATGTCCTGACCAATCTGTGGCCCACTGTGTGCCAGTTCACGACATTCGGTCTCCAGTGTGGAGGAAAGTGACCCATCCCAGTAAATGCAGCACCCAGGAGCTGGACATAGAATCTGAGTA
CAAAGCCATCCTTGGCTATAAGGCTTTCGTGGCACAACCCAGGCCTGTCTAAACCTCGGAAGGCTTGTTTGCTACTTTCAAACAAGAACACCAAAGTCTGGTTGCAACAGGAACTTCACAGTCGAAAA
AGCTTAAAATGTAGCCTGGGCCTGGGCTTGTCCACCTCAATACAGCAAACTTTTGACAGCCCCTCACTGTGGAATGACACCACAGACATTTCACACCTAATATAAAGCTGGTGGGAGCAACACCACTG
TACCCTCAGAGACTGGTTCTCCCTCAAAACTGTCACTGCTAAACAGGTAAGAGTGTTCGCAGCAGGGTTGGGGGAGGGGTCAAGCAAATGTCATTCCACAGCCTGGAAATCCTAATCTTCCTTTAATA
AGAGTTAACCTCCTCCTAAGGTTTTCCTCATTGTATACTAAAAGCAAGTGTTCGTTACCTCGGTGAAATCTGCCGGAACTAGCATGTATTTGCCACTGGAACAAACAATGGGTTTTTCTTAATTAATA
AAACATTAACATGAAAATGTCAAAAAATGAA

hide sequence


Protein RefSeqs	NP_001103143	(Get FASTA)	NCBI Sequence Viewer
	XP_006244398	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI29099	(Get FASTA)	NCBI Sequence Viewer
	AAI69032	(Get FASTA)	NCBI Sequence Viewer
	EDL83681	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067468
	ENSRNOP00000067468.2
	ENSRNOP00000089807

RefSeq Acc Id:

NP_001103143 ⟸ NM_001109673

- UniProtKB:

A2VD11 (UniProtKB/TrEMBL), A6KR23 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRMQKEREDE
ELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLLQHRLSQEQWQQQQEEEDERETVALLEEARYRRLLDDSDSEDEAPPSQPQAAARPNPTAILDEVPKTKRKAEGLCRKAQLAGL
VIPKKAKTEANRVSEQVRVPTTGAPESRKVANPAPQTPGASSLSQLGAYGDSEDSDS

hide sequence

RefSeq Acc Id:	XP_006244398 ⟸ XM_006244336
- Peptide Label:	isoform X1
- UniProtKB:	A6KR23 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQ NEAYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRMQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLLQHRLSQEQWQQQQEEEDE RETVALLEEARYRRLLDDSDSEDEAPPSQPQAAARPNPTAILDEVPPRAGRWPTLHPRHLVPPP hide sequence

Ensembl Acc Id:

ENSRNOP00000067468 ⟸ ENSRNOT00000072357

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A2VD11-F1-model_v2	AlphaFold	A2VD11	1-313	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13696476

Promoter ID:

EPDNEW_R7001

Type:

initiation region

Name:

Ccdc94_1

Description:

coiled-coil domain containing 94

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	11,108,774 - 11,108,834	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-28572	BioCyc
Ensembl Genes	ENSRNOG00000047456	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072357	ENTREZGENE
	ENSRNOT00000072357.2	UniProtKB/TrEMBL
	ENSRNOT00000106114	ENTREZGENE
IMAGE_CLONE	IMAGE:8373484	IMAGE-MGC_LOAD
InterPro	DUF572	UniProtKB/TrEMBL
	Yju2	UniProtKB/TrEMBL
KEGG Report	rno:501285	UniProtKB/TrEMBL
MGC_CLONE	MGC:156684	IMAGE-MGC_LOAD
NCBI Gene	501285	ENTREZGENE
PANTHER	DUF572	UniProtKB/TrEMBL
	SPLICING FACTOR YJU2	UniProtKB/TrEMBL
Pfam	DUF572	UniProtKB/TrEMBL
PhenoGen	Yju2	PhenoGen
RatGTEx	ENSRNOG00000047456	RatGTEx
UniProt	A2VD11	ENTREZGENE, UniProtKB/TrEMBL
	A6KR23	ENTREZGENE, UniProtKB/TrEMBL
	M0RCY0_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-05-13	Yju2	YJU2 splicing factor	Yju2	YJU2 splicing factor homolog	Name changed	629549	APPROVED
2018-03-01	Yju2	YJU2 splicing factor homolog	Ccdc94	coiled-coil domain containing 94	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Ccdc94	coiled-coil domain containing 94	LOC501285	similar to CG8435-PA	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC501285	similar to CG8435-PA			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar