Advanced Search (OLGA)

Gene: Bsx (brain specific homeobox) Rattus norvegicus

Subscribe to Updates

Analyze

Symbol:

Bsx

Name:

brain specific homeobox

RGD ID:

1565120

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of transcription by RNA polymerase II; and stem cell population maintenance. Predicted to act upstream of or within several processes, including eating behavior; mammary gland involution; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human BSX (brain specific homeobox); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; lead diacetate.

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

brain-specific homeobox protein homolog; LOC500982; RGD1565120; similar to brain-specific homeodomain protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BSX (brain specific homeobox)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Bsx (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bsx (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BSX (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BSX (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BSX (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BSX (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bsx (brain specific homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	VWA2 (von Willebrand factor A domain containing 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Bsx (brain specific homeobox)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BSX (brain specific homeobox)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bsx (brain-specific homeobox)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bsh	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	tab-1	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	bsx	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	50,151,204 - 50,154,960 (+)	NCBI		GRCr8
mRatBN7.2	8	41,254,105 - 41,257,861 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	41,254,105 - 41,257,861 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	46,753,980 - 46,757,730 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	45,032,569 - 45,036,319 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	42,900,173 - 42,903,923 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	45,061,670 - 45,065,430 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	45,061,670 - 45,065,430 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	43,548,484 - 43,552,239 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	43,855,822 - 43,860,107 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	40,853,382 - 40,857,138 (+)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Bsx	Rat	chromosome 11 partial duplication syndrome		ISO	BSX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Distal trisomy 11q	ClinVar	PMID:25741868
Bsx	Rat	Dwarfism		ISO	BSX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Short stature	ClinVar	PMID:32581362
Bsx	Rat	schizophrenia		ISO	BSX (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Bsx	Rat	1,2-dichloroethane	decreases expression	ISO	Bsx (Mus musculus)	6480464	ethylene dichloride results in decreased expression of BSX mRNA	CTD	PMID:28960355
Bsx	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Bsx (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of BSX mRNA	CTD	PMID:24058054
Bsx	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of BSX mRNA	CTD	PMID:32109520
Bsx	Rat	3,4-methylenedioxymethamphetamine	decreases expression	ISO	Bsx (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of BSX mRNA	CTD	PMID:20188158
Bsx	Rat	aflatoxin B1	decreases methylation	ISO	BSX (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of BSX gene and Aflatoxin B1 results in decreased methylation of BSX intron	CTD	PMID:27153756 and PMID:30157460
Bsx	Rat	amosite asbestos	decreases methylation	ISO	BSX (Homo sapiens)	6480464	Asbestos and Amosite results in decreased methylation of BSX promoter	CTD	PMID:29626692
Bsx	Rat	benzo[a]pyrene	increases methylation	ISO	BSX (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of BSX promoter	CTD	PMID:27901495
Bsx	Rat	benzo[a]pyrene	affects methylation	ISO	BSX (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of BSX exon and Benzo(a)pyrene affects the methylation of BSX intron	CTD	PMID:27901495 and PMID:30157460
Bsx	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of BSX mRNA	CTD	PMID:25181051
Bsx	Rat	cadmium atom	multiple interactions	ISO	BSX (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BSX mRNA	CTD	PMID:35301059
Bsx	Rat	cadmium dichloride	increases expression	ISO	BSX (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of BSX mRNA	CTD	PMID:38568856
Bsx	Rat	cadmium dichloride	multiple interactions	ISO	BSX (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BSX mRNA	CTD	PMID:35301059
Bsx	Rat	crocidolite asbestos	decreases methylation	ISO	BSX (Homo sapiens)	6480464	Asbestos and Crocidolite results in decreased methylation of BSX promoter	CTD	PMID:29626692
Bsx	Rat	cyclosporin A	decreases methylation	ISO	BSX (Homo sapiens)	6480464	Cyclosporine results in decreased methylation of BSX promoter	CTD	PMID:27989131
Bsx	Rat	lead diacetate	decreases expression	EXP		6480464	lead acetate results in decreased expression of BSX mRNA	CTD	PMID:22641619
Bsx	Rat	resveratrol	multiple interactions	ISO	BSX (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of BSX mRNA	CTD	PMID:23557933
Bsx	Rat	titanium dioxide	decreases methylation	ISO	Bsx (Mus musculus)	6480464	titanium dioxide results in decreased methylation of BSX gene	CTD	PMID:35295148
Bsx	Rat	triptonide	increases expression	ISO	Bsx (Mus musculus)	6480464	triptonide results in increased expression of BSX mRNA	CTD	PMID:33045310

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Bsx	Rat	cell differentiation	involved_in	IBA	FB:FBgn0000529 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Bsx	Rat	eating behavior	acts_upstream_of_or_within	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	eating behavior	acts_upstream_of_or_within	ISO	Bsx (Mus musculus)	1624291	MGI:3716209 PMID:17550780	RGD	PMID:17550780
Bsx	Rat	locomotory behavior	acts_upstream_of_or_within	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	locomotory behavior	acts_upstream_of_or_within	ISO	Bsx (Mus musculus)	1624291	MGI:3716209 PMID:17550780	RGD	PMID:17550780
Bsx	Rat	mammary gland involution	acts_upstream_of_or_within	ISO	Bsx (Mus musculus)	1624291	MGI:3719242 more ...	RGD	PMID:17485440
Bsx	Rat	mammary gland involution	acts_upstream_of_or_within	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	positive regulation of transcription by RNA polymerase II	involved_in	ISO	Bsx (Mus musculus) and PR:Q810B3-1	1624291	PMID:17353277	RGD	PMID:17353277
Bsx	Rat	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	ISO	Bsx (Mus musculus)	1624291	MGI:1890077 PMID:17550780	RGD	PMID:17550780
Bsx	Rat	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR017970	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Bsx	Rat	regulation of transcription by RNA polymerase II	involved_in	IBA	MGI:101926 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Bsx	Rat	stem cell population maintenance	involved_in	IBA	MGI:1919200 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Bsx	Rat	nucleus	located_in	ISO	Bsx (Mus musculus)	1624291	PMID:17550780	RGD	PMID:17550780
Bsx	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Bsx	Rat	nucleus	located_in	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	nucleus	located_in	IEA	UniRule:UR000401037	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Bsx	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Bsx	Rat	transcription regulator complex	part_of	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	transcription regulator complex	part_of	ISO	Bsx (Mus musculus)	1624291	PMID:17550780	RGD	PMID:17550780

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Bsx	Rat	DNA binding	enables	IEA	UniRule:UR000401037	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Bsx	Rat	DNA binding	enables	IEA	InterPro:IPR001356 and InterPro:IPR020479	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Bsx	Rat	DNA binding	enables	IEA	UniProtKB-KW:KW-0238 and UniProtKB-KW:KW-0371	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Bsx	Rat	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	ISO	Bsx (Mus musculus) and PR:Q810B3-1	1624291	PMID:17353277	RGD	PMID:17353277
Bsx	Rat	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	InterPro:IPR017970	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Bsx	Rat	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	MGI:101926 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Bsx	Rat	protein binding	enables	ISO	Bsx (Mus musculus)	1624291	PR:Q01147 PMID:17550780	RGD	PMID:17550780
Bsx	Rat	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	ISO	Bsx (Mus musculus) and PR:Q810B3-1	1624291	PMID:17353277	RGD	PMID:17353277
Bsx	Rat	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:101926 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Bsx	Rat	sequence-specific DNA binding	enables	ISO	Bsx (Mus musculus)	1624291	PMID:17550780	RGD	PMID:17550780
Bsx	Rat	sequence-specific DNA binding	enables	IEA	UniProtKB:Q810B3 and ensembl:ENSMUSP00000068057	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Bsx	Rat	sequence-specific double-stranded DNA binding	enables	ISO	BSX (Homo sapiens)	1624291	PMID:28473536	RGD	PMID:28473536
Bsx	Rat	sequence-specific double-stranded DNA binding	enables	IEA	UniProtKB:Q3C1V8 and ensembl:ENSP00000344285	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:17353277	PMID:17485440	PMID:17550780	PMID:20335227	PMID:31808568

Bsx
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	50,151,204 - 50,154,960 (+)	NCBI		GRCr8
mRatBN7.2	8	41,254,105 - 41,257,861 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	41,254,105 - 41,257,861 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	46,753,980 - 46,757,730 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	45,032,569 - 45,036,319 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	42,900,173 - 42,903,923 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	45,061,670 - 45,065,430 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	45,061,670 - 45,065,430 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	43,548,484 - 43,552,239 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	43,855,822 - 43,860,107 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	40,853,382 - 40,857,138 (+)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

BSX
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	122,977,570 - 122,981,834 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	122,977,570 - 122,981,834 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	122,848,278 - 122,852,542 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	122,353,567 - 122,357,589 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	120,007,843 - 120,011,864 (-)	NCBI		Celera
Cytogenetic Map	11	q24.1	NCBI
HuRef	11	118,791,194 - 118,795,215 (-)	NCBI		HuRef
CHM1_1	11	122,734,114 - 122,738,138 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	123,005,290 - 123,009,556 (-)	NCBI		T2T-CHM13v2.0

Bsx
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	40,782,994 - 40,790,258 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	40,785,423 - 40,791,353 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	40,874,127 - 40,878,962 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	40,874,127 - 40,880,057 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	40,682,210 - 40,686,055 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	40,625,196 - 40,629,041 (+)	NCBI		MGSCv36	mm8
Celera	9	38,108,339 - 38,112,231 (+)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	21.65	NCBI

Bsx
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	23,797,630 - 23,801,479 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	23,796,973 - 23,801,479 (-)	NCBI	ChiLan1.0	ChiLan1.0

BSX
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	123,675,988 - 123,683,677 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	124,780,810 - 124,788,435 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	117,807,856 - 117,815,571 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	121,731,049 - 121,735,101 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	121,731,049 - 121,735,101 (-)	Ensembl	panpan1.1		panPan2

BSX
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	11,365,635 - 11,369,575 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	11,365,805 - 11,369,575 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	11,421,482 - 11,425,252 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	11,316,513 - 11,320,283 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	11,316,513 - 11,320,283 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	11,419,843 - 11,423,613 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	11,358,923 - 11,362,696 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	11,396,771 - 11,400,541 (+)	NCBI		UU_Cfam_GSD_1.0

BSX
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	49,905,428 - 49,909,226 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	49,873,031 - 49,910,581 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	55,249,305 - 55,254,781 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BSX
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	114,366,225 - 114,373,943 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	114,368,217 - 114,372,282 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	11,756,497 - 11,762,214 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bsx
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624880	2,131,722 - 2,135,685 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624880	2,128,744 - 2,137,465 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Bsx
37 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	105
Count of miRNA genes:	88
Interacting mature miRNAs:	94
Transcripts:	ENSRNOT00000028909
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30856404	75856404	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	30848154	101699754	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	30848154	61290444	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	30848154	101699754	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	31737729	76737729	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	35582032	80582032	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	42692818	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	30848154	101699754	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	28242912	73242912	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	28242912	99525068	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	30848154	82460899	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	27205715	99103503	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	19331152	93965294	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	29502665	70386295	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	22662330	67662330	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	40713066	82925667	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	35551938	80551938	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	40713066	93965294	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	27205715	99103503	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	58482492	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30848259	105647037	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	27205715	99103503	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	26644912	46711092	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	16290444	61290444	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	30848154	82460899	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	30188867	94457446	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	28242912	53961020	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	30848154	82460899	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2097640	47097640	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2097640	47097640	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2097640	47097640	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	14906751	59906751	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	29502665	50095447	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2097640	47097640	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	27205715	54998217	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	36469535	99083736	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	18984168	84531599	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	26130187	71130187	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	30848154	82460899	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	26130187	71130187	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

circulatory system	ectoderm	endocrine system	mesenchyme	mesoderm	nervous system	renal system	reproductive system
1	57	2	18	3	57	15	18


RefSeq Transcripts	NM_001191995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000028909 ⟹ ENSRNOP00000030106

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	41,254,105 - 41,257,861 (+)	Ensembl
Rnor_6.0 Ensembl	8	45,061,670 - 45,065,430 (+)	Ensembl

RefSeq Acc Id:

NM_001191995 ⟹ NP_001178924

RefSeq Status:

INFERRED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	50,151,204 - 50,154,960 (+)	NCBI
mRatBN7.2	8	41,254,105 - 41,257,861 (+)	NCBI
Rnor_6.0	8	45,061,670 - 45,065,430 (+)	NCBI
Rnor_5.0	8	43,548,484 - 43,552,239 (+)	NCBI
Celera	8	40,853,382 - 40,857,138 (+)	NCBI

Sequence:

show sequence

CTGCACTTTGTCCGGGCCCTCGCCCCGTGCCAGGCGCTCTGCAAGATGAATCTCAACTTCACTTCCCCTCTCCATCCAGCATCTTCTCAGAGGCCCACGTCGTTTTTCATCGAGGACATTCTGCTACA
CAAGCCCAAGCCGTTGAGGGAAGTGGCCCCTGACCACTTTGCCAGCTCTCTGGCCTCTAGGGTGCCTTTGCTAGACTATGGCTACCCCCTTATGCCCACACCCACCCTCCTCACCCCTCACACTCATC
ATCCTCTGCATAAGGGGGAGCATCATCACCCTTATTTCCTGGCCACCTCAGGGATGCCGGTCCCGGCTCTGTTCCCGCACCCGCAGCATGCAGAGCTACCCGGGAAGCACTGCCGCCGCCGCAAAGCT
CGCACGGTGTTTTCTGACTCGCAGCTCTCCGGCCTGGAGAAAAGGTTCGAAATCCAGCGCTACCTGTCGACACCAGAGCGTGTGGAGCTGGCCACTGCTCTCAGCCTCTCTGAGACTCAGGTGAAAAC
GTGGTTCCAGAACCGGCGGATGAAGCATAAAAAACAGCTGAGGAAAAGTCAAGACGAACCCAAAGCCGCAGACGGGCCTGAGAGCCCAGAGGGCAGCCCTCGTGCTCCCGAGGGCGCGCCCGCCGACG
CTCGGCTGAGTTTGCCGGCCGGTGCCTTCGTGCTTACAGAGCCGGAGGACGAGGTGGACATTGGGGACGAAGGCGAGCTCAGCTCAGGGCCGCACGTGCTCTGAGTGGCCAGGCTGGGAAGGGAGACC
CGGGCGAGGAGGCTGTGGGGCCAGACCCGGTTCTTTCCGGGCGAGAAGACTCGCGGAGACTCTAGACTGTTCCTGCGGCCTGGACTGGAAGAAAGAAAGGC

hide sequence


Protein RefSeqs	NP_001178924	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030106
	ENSRNOP00000030106.3

RefSeq Acc Id:

NP_001178924 ⟸ NM_001191995

- UniProtKB:

D4A5F6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHTHHPLHKGEHHHPYFLATSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKR
FEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPESPEGSPRAPEGAPADARLSLPAGAFVLTEPEDEVDIGDEGELSSGPHVL

hide sequence

Ensembl Acc Id:

ENSRNOP00000030106 ⟸ ENSRNOT00000028909

Protein Domains

Homeobox

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A5F6-F1-model_v2	AlphaFold	D4A5F6	1-232	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-30827	BioCyc
Ensembl Genes	ENSRNOG00000024438	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000028909	ENTREZGENE
	ENSRNOT00000028909.5	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_region	UniProtKB/TrEMBL
	Homeobox_TF	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
KEGG Report	rno:500982	UniProtKB/TrEMBL
NCBI Gene	500982	ENTREZGENE
PANTHER	BRAIN-SPECIFIC HOMEOBOX	UniProtKB/TrEMBL
	HOMEO BOX HB9 LIKE A-RELATED	UniProtKB/TrEMBL
Pfam	Homeobox	UniProtKB/TrEMBL
PhenoGen	Bsx	PhenoGen
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024438	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	D4A5F6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Bsx	brain specific homeobox	RGD1565120_predicted	similar to brain-specific homeodomain protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565120_predicted	similar to brain-specific homeodomain protein (predicted)	LOC500982	similar to brain-specific homeodomain protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC500982	similar to brain-specific homeodomain protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Send us a Message

Imported Disease Annotations - ClinVar