BSX (brain specific homeobox) - Rat Genome Database

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Gene: BSX (brain specific homeobox) Chlorocebus sabaeus
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Symbol: BSX
Name: brain specific homeobox
RGD ID: 18507092
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); schizophrenia (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: brain-specific homeobox protein homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,366,225 - 114,373,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,368,217 - 114,372,282 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604311,756,497 - 11,762,214 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BSXGreen Monkeychromosome 11 partial duplication syndrome  ISOBSX (Homo sapiens)8554872ClinVar Annotator: match by term: Distal trisomy 11qClinVarPMID:25741868
BSXGreen MonkeyDwarfism  ISOBSX (Homo sapiens)8554872ClinVar Annotator: match by term: Short statureClinVarPMID:32581362
BSXGreen Monkeyschizophrenia  ISOBSX (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BSXGreen Monkeyeating behavior acts_upstream_of_or_withinIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107
BSXGreen Monkeylocomotory behavior acts_upstream_of_or_withinIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107
BSXGreen Monkeymammary gland involution acts_upstream_of_or_withinIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107
BSXGreen Monkeypositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107
BSXGreen Monkeypositive regulation of transcription by RNA polymerase II involved_inISOBsx (Mus musculus)9068941 PMID:17353277NTNU_SBPMID:17353277
BSXGreen Monkeyregulation of DNA-templated transcription involved_inIEAInterPro:IPR017970150520179 InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BSXGreen Monkeynucleus located_inIEAUniRule:UR000401037150520179 UniProtGO_REF:0000104
BSXGreen Monkeynucleus located_inIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107
BSXGreen Monkeynucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
BSXGreen Monkeynucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
BSXGreen Monkeytranscription regulator complex part_ofIEAUniProtKB:Q810B3 and ensembl:ENSMUSP00000068057150520179 EnsemblGO_REF:0000107

Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows

PMID:22301074  



BSX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,366,225 - 114,373,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,368,217 - 114,372,282 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604311,756,497 - 11,762,214 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BSX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811122,977,570 - 122,981,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11122,977,570 - 122,981,834 (-)EnsemblGRCh38hg38GRCh38
GRCh3711122,848,278 - 122,852,542 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611122,353,567 - 122,357,589 (-)NCBINCBI36Build 36hg18NCBI36
Celera11120,007,843 - 120,011,864 (-)NCBICelera
Cytogenetic Map11q24.1NCBI
HuRef11118,791,194 - 118,795,215 (-)NCBIHuRef
CHM1_111122,734,114 - 122,738,138 (-)NCBICHM1_1
T2T-CHM13v2.011123,005,290 - 123,009,556 (-)NCBIT2T-CHM13v2.0
Bsx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39940,782,994 - 40,790,258 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl940,785,423 - 40,791,353 (+)EnsemblGRCm39 Ensembl
GRCm38940,874,127 - 40,878,962 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl940,874,127 - 40,880,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv37940,682,210 - 40,686,055 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36940,625,196 - 40,629,041 (+)NCBIMGSCv36mm8
Celera938,108,339 - 38,112,231 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map921.65NCBI
Bsx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8850,151,204 - 50,154,960 (+)NCBIGRCr8
mRatBN7.2841,254,105 - 41,257,861 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl841,254,105 - 41,257,861 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx846,753,980 - 46,757,730 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0845,032,569 - 45,036,319 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0842,900,173 - 42,903,923 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0845,061,670 - 45,065,430 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl845,061,670 - 45,065,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0843,548,484 - 43,552,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4843,855,822 - 43,860,107 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera840,853,382 - 40,857,138 (+)NCBICelera
Cytogenetic Map8q22NCBI
Bsx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541223,797,630 - 23,801,479 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541223,796,973 - 23,801,479 (-)NCBIChiLan1.0ChiLan1.0
BSX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29123,675,988 - 123,683,677 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111124,780,810 - 124,788,435 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011117,807,856 - 117,815,571 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111121,731,049 - 121,735,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11121,731,049 - 121,735,101 (-)Ensemblpanpan1.1panPan2
BSX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1511,365,635 - 11,369,575 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl511,365,805 - 11,369,575 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha511,421,482 - 11,425,252 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0511,316,513 - 11,320,283 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl511,316,513 - 11,320,283 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1511,419,843 - 11,423,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0511,358,923 - 11,362,696 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0511,396,771 - 11,400,541 (+)NCBIUU_Cfam_GSD_1.0
BSX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl949,905,428 - 49,909,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1949,873,031 - 49,910,581 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2955,249,305 - 55,254,781 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Bsx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248802,131,722 - 2,135,685 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248802,128,744 - 2,137,465 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in BSX
197 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
2 2 17 17 17 2 2


RefSeq Transcripts XM_008021260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000000431   ⟹   ENSCSAP00000015628
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1114,368,217 - 114,372,282 (-)Ensembl
RefSeq Acc Id: XM_008021260   ⟹   XP_008019451
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11114,366,225 - 114,373,943 (-)NCBI
Vero_WHO_p1.0NW_02366604311,756,497 - 11,762,214 (+)NCBI
Sequence:
Protein RefSeqs XP_008019451 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015628
  ENSCSAP00000015628.1
RefSeq Acc Id: XP_008019451   ⟸   XM_008021260
- UniProtKB: A0A0D9S439 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000015628   ⟸   ENSCSAT00000000431



1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000002413 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000431.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
  Homeobox_TF UniProtKB/TrEMBL
KEGG Report csab:103248690 UniProtKB/TrEMBL
NCBI Gene BSX ENTREZGENE
PANTHER BRAIN-SPECIFIC HOMEOBOX UniProtKB/TrEMBL
  HOMEO BOX HB9 LIKE A-RELATED UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A0D9S439 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows