Kcp (kielin cysteine rich BMP regulator) - Rat Genome Database

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Gene: Kcp (kielin cysteine rich BMP regulator) Rattus norvegicus
Analyze
Symbol: Kcp
Name: kielin cysteine rich BMP regulator
RGD ID: 1561119
Description: Predicted to be involved in hematopoietic progenitor cell differentiation and positive regulation of BMP signaling pathway. Predicted to localize to extracellular space. Orthologous to human KCP (kielin cysteine rich BMP regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Crim2; cysteine rich BMP regulator 2 (chordin like); involucrin-like; kielin/chordin-like protein; LOC102555244; LOC296952; RGD1561119; similar to kielin-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
Rnor_6.0 Ensembl456,760,220 - 56,786,754 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0456,750,782 - 56,796,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0456,527,313 - 56,562,303 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,362,648 - 56,389,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera453,181,654 - 53,227,746 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15793581   PMID:24029230  


Genomics

Comparative Map Data
Kcp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
Rnor_6.0 Ensembl456,760,220 - 56,786,754 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0456,750,782 - 56,796,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0456,527,313 - 56,562,303 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,362,648 - 56,389,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera453,181,654 - 53,227,746 (-)NCBICelera
Cytogenetic Map4q22NCBI
KCP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7128,862,042 - 128,910,719 (-)EnsemblGRCh38hg38GRCh38
GRCh387128,870,645 - 128,910,719 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377128,516,919 - 128,550,763 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,318,191 - 128,337,966 (-)NCBINCBI36hg18NCBI36
Celera7123,313,433 - 123,347,287 (-)NCBI
Cytogenetic Map7q32.1NCBI
HuRef7122,878,556 - 122,912,025 (-)NCBIHuRef
CHM1_17128,450,213 - 128,484,063 (-)NCBICHM1_1
CRA_TCAGchr7v27127,900,664 - 127,934,517 (-)NCBI
Kcp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,473,161 - 29,508,006 (-)NCBIGRCm39mm39
GRCm39 Ensembl629,473,161 - 29,507,951 (-)Ensembl
GRCm38629,473,162 - 29,508,003 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,473,162 - 29,507,952 (-)EnsemblGRCm38mm10GRCm38
MGSCv37629,432,036 - 29,457,934 (-)NCBIGRCm37mm9NCBIm37
MGSCv36629,432,046 - 29,457,947 (-)NCBImm8
Celera629,489,910 - 29,515,855 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
Kcp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554799,670,430 - 9,727,275 (-)NCBIChiLan1.0ChiLan1.0
KCP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17133,353,386 - 133,387,202 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7133,353,558 - 133,387,170 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07120,822,442 - 120,861,638 (-)NCBIMhudiblu_PPA_v0panPan3
KCP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,752,162 - 7,776,428 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,751,351 - 7,780,558 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,439,042 - 7,463,109 (+)NCBI
ROS_Cfam_1.0147,518,053 - 7,542,127 (+)NCBI
UMICH_Zoey_3.1147,723,081 - 7,747,150 (+)NCBI
UNSW_CanFamBas_1.0147,465,097 - 7,489,152 (+)NCBI
UU_Cfam_GSD_1.0147,610,499 - 7,634,756 (+)NCBI
LOC101974992
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511854,677,380 - 54,702,823 (-)NCBI
SpeTri2.0NW_00493647915,801,196 - 15,826,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1819,711,112 - 19,741,637 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,689,111 - 19,741,641 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,758,697 - 20,811,227 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103226871
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12197,479,087 - 97,510,949 (-)NCBI
Vero_WHO_p1.0NW_0236660425,891,814 - 5,929,350 (+)NCBI
Kcp
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247837,290,663 - 7,316,866 (+)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4304323179575658Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4304401764915903Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)4734240492484039Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41263897457638974Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41614994161149941Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)41822218761039065Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42399172176238799Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42399172176238799Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)42463187469631874Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42665474981874227Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)429549895112807890Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43182556083531021Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43182556083531021Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43182556083531021Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)43363780361708341Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43427793299067150Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)436615599145611886Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43768517573066691Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43770327275345433Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)437703272115372927Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)43920822284208222Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)43920824784208247Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44241577787415777Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)443414605155469929Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)443414792146942075Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)443414792146942075Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)446898276145611886Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)449906054145611886Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45532485779575658Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45532485779575658Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45532485779575658Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45532485779575658Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)455324953148360954Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)455375865125671711Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45579156482134846Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45579156492484312Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45579183479557856Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)456092756101092756Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)456092756101092756Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:106
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000050644, ENSRNOT00000050795
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 2 2 20 30
Low 31 32 29 4 29 5 8 72 15 11 11 5
Below cutoff 3 10 23 10 15 10 3 3 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008762841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000050795   ⟹   ENSRNOP00000043530
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl456,760,220 - 56,786,754 (-)Ensembl
RefSeq Acc Id: XM_008762841   ⟹   XP_008761063
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0456,750,782 - 56,796,878 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008775690   ⟹   XP_008773912
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera453,181,654 - 53,227,746 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592967   ⟹   XP_017448456
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
Rnor_6.0456,760,152 - 56,796,878 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592968   ⟹   XP_017448457
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0456,763,393 - 56,796,878 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592969   ⟹   XP_017448458
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0456,770,782 - 56,796,878 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602768   ⟹   XP_017458257
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera453,190,758 - 53,227,746 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602769   ⟹   XP_017458258
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera453,194,261 - 53,227,746 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602770   ⟹   XP_017458259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera453,201,650 - 53,227,746 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108993   ⟹   XP_038964921
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039108995   ⟹   XP_038964923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039108996   ⟹   XP_038964924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,083 (-)NCBI
RefSeq Acc Id: XM_039108997   ⟹   XP_038964925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039108998   ⟹   XP_038964926
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039108999   ⟹   XP_038964927
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,104,694 (-)NCBI
RefSeq Acc Id: XM_039109000   ⟹   XP_038964928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,104,694 (-)NCBI
RefSeq Acc Id: XM_039109001   ⟹   XP_038964929
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,104,694 (-)NCBI
RefSeq Acc Id: XM_039109002   ⟹   XP_038964930
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,087,965 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039109004   ⟹   XP_038964932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,089,317 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039109005   ⟹   XP_038964933
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,099,362 (-)NCBI
RefSeq Acc Id: XM_039109006   ⟹   XP_038964934
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,093,270 - 58,118,170 (-)NCBI
RefSeq Acc Id: XM_039109007   ⟹   XP_038964935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,082,856 - 58,098,315 (-)NCBI
RefSeq Acc Id: XM_039109008   ⟹   XP_038964936
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,094,636 - 58,118,170 (-)NCBI
RefSeq Acc Id: XR_005504136
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,085,161 - 58,118,170 (-)NCBI
RefSeq Acc Id: XR_005504137
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,085,161 - 58,118,170 (-)NCBI
RefSeq Acc Id: XR_005504138
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,087,181 - 58,118,170 (-)NCBI
RefSeq Acc Id: XR_005504139
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,093,142 - 58,118,170 (-)NCBI
RefSeq Acc Id: XR_005504140
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2458,094,633 - 58,118,170 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_008773912   ⟸   XM_008775690
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008761063   ⟸   XM_008762841
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017458257   ⟸   XM_017602768
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017458258   ⟸   XM_017602769
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017458259   ⟸   XM_017602770
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017448456   ⟸   XM_017592967
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017448457   ⟸   XM_017592968
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017448458   ⟸   XM_017592969
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000043530   ⟸   ENSRNOT00000050795
RefSeq Acc Id: XP_038964925   ⟸   XM_039108997
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038964923   ⟸   XM_039108995
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038964926   ⟸   XM_039108998
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038964921   ⟸   XM_039108993
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038964924   ⟸   XM_039108996
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038964927   ⟸   XM_039108999
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038964928   ⟸   XM_039109000
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038964929   ⟸   XM_039109001
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038964933   ⟸   XM_039109005
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038964935   ⟸   XM_039109007
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038964930   ⟸   XM_039109002
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038964932   ⟸   XM_039109004
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038964934   ⟸   XM_039109006
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038964936   ⟸   XM_039109008
- Peptide Label: isoform X14
Protein Domains
VWFC   VWFD

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561119 AgrOrtholog
Ensembl Genes ENSRNOG00000021855 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000043530 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050795 UniProtKB/TrEMBL
InterPro Ser_inhib-like_sf UniProtKB/TrEMBL
  Unchr_dom_Cys-rich UniProtKB/TrEMBL
  von_Willebrand_fac_D UniProtKB/TrEMBL
  VWF_C UniProtKB/TrEMBL
NCBI Gene 296952 ENTREZGENE
Pfam VWC UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
PhenoGen Kcp PhenoGen
PROSITE VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
  VWFD UniProtKB/TrEMBL
SMART SM00832 UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
Superfamily-SCOP Cysrich_TIL UniProtKB/TrEMBL
UniProt D3ZGP6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-21 Kcp  kielin cysteine rich BMP regulator  Kcp  kielin/chordin-like protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Kcp  kielin/chordin-like protein  LOC102555244  involucrin-like  Data Merged 737654 PROVISIONAL
2013-12-18 LOC102555244  involucrin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-02-23 Kcp  kielin/chordin-like protein  Crim2  cysteine rich BMP regulator 2 (chordin like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Crim2  cysteine rich BMP regulator 2 (chordin like)  RGD1561119_predicted  similar to kielin-like (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561119_predicted  similar to kielin-like (predicted)  LOC296952  similar to kielin-like  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC296952  similar to kielin-like      Symbol and Name status set to provisional 70820 PROVISIONAL