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Gene: Kcp (kielin cysteine rich BMP regulator) Rattus norvegicus

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Symbol:

Kcp

Name:

kielin cysteine rich BMP regulator

RGD ID:

1561119

Description:

Predicted to be involved in positive regulation of BMP signaling pathway. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Orthologous to human KCP (kielin cysteine rich BMP regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Crim2; cysteine rich BMP regulator 2 (chordin like); involucrin-like; kielin/chordin-like protein; LOC102555244; LOC296952; RGD1561119; similar to kielin-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KCP (kielin cysteine rich BMP regulator)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Kcp (kielin/chordin-like protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kcp (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KCP (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KCP (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kcp (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KCP (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KCP (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kcp (kielin cysteine rich BMP regulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PLCG2 (phospholipase C gamma 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Kcp (kielin/chordin-like protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	KCP (kielin cysteine rich BMP regulator)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-266m15.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	kcp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	59,048,209 - 59,083,522 (-)	NCBI		GRCr8
mRatBN7.2	4	58,082,856 - 58,118,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	58,082,857 - 58,109,768 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	56,750,782 - 56,796,878 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	56,760,220 - 56,786,754 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	56,527,313 - 56,562,303 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	56,362,648 - 56,389,182 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	53,181,654 - 53,227,746 (-)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcp	Rat	autosomal dominant limb-girdle muscular dystrophy type 2		ISO	RGD:1601689	8554872	ClinVar Annotator: match by term: Autosomal dominant limb-girdle muscular dystrophy type 1F	ClinVar	PMID:28492532
Kcp	Rat	myofibrillar myopathy 5		ISO	RGD:1601689	8554872	ClinVar Annotator: match by term: Myofibrillar myopathy 5	ClinVar	PMID:15929027\|PMID:22961544\|PMID:27908349\|PMID:28492532
Kcp	Rat	pleomorphic xanthoastrocytoma		ISO	RGD:1601689	8554872	ClinVar Annotator: match by term: Pleomorphic xanthoastrocytoma	ClinVar	PMID:28299358

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcp	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of KCP mRNA	CTD	PMID:32109520
Kcp	Rat	2,3,7,8-Tetrachlorodibenzofuran	increases expression	EXP		6480464	2,3,7,8-tetrachlorodibenzofuran results in increased expression of KCP mRNA	CTD	PMID:32109520
Kcp	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1557784	6480464	bisphenol S results in increased expression of KCP mRNA	CTD	PMID:30951980
Kcp	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	RGD:1557784	6480464	bisphenol S affects the methylation of KCP gene	CTD	PMID:31683443
Kcp	Rat	7,12-dimethyltetraphene	increases expression	ISO	RGD:1557784	6480464	9,10-Dimethyl-1,2-benzanthracene results in increased expression of KCP protein	CTD	PMID:39910959
Kcp	Rat	actinomycin D	multiple interactions	ISO	RGD:1601689	6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of KCP mRNA	CTD	PMID:38460933
Kcp	Rat	aflatoxin B1	increases methylation	ISO	RGD:1601689	6480464	Aflatoxin B1 results in increased methylation of KCP intron	CTD	PMID:30157460
Kcp	Rat	arsenite(3-)	increases methylation	ISO	RGD:1601689	6480464	arsenite results in increased methylation of KCP promoter	CTD	PMID:23974009
Kcp	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1601689	6480464	Benzo(a)pyrene results in increased expression of KCP mRNA	CTD	PMID:20064835\|PMID:32234424
Kcp	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1601689	6480464	Benzo(a)pyrene results in increased methylation of KCP 3' UTR	CTD	PMID:27901495
Kcp	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1601689	6480464	Benzo(a)pyrene affects the methylation of KCP promoter	CTD	PMID:27901495
Kcp	Rat	benzo[b]fluoranthene	increases expression	ISO	RGD:1557784	6480464	benzo(b)fluoranthene results in increased expression of KCP mRNA	CTD	PMID:26377693
Kcp	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1601689	6480464	Diethylhexyl Phthalate results in decreased expression of KCP mRNA	CTD	PMID:36774801
Kcp	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of KCP mRNA	CTD	PMID:25181051
Kcp	Rat	bisphenol A	decreases methylation	ISO	RGD:1601689	6480464	bisphenol A results in decreased methylation of KCP gene	CTD	PMID:31601247
Kcp	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of KCP mRNA	CTD	PMID:30816183
Kcp	Rat	bisphenol A	increases expression	ISO	RGD:1557784	6480464	bisphenol A results in increased expression of KCP mRNA	CTD	PMID:30951980
Kcp	Rat	bisphenol F	increases expression	ISO	RGD:1557784	6480464	bisphenol F results in increased expression of KCP mRNA	CTD	PMID:30951980
Kcp	Rat	bisphenol F	decreases expression	ISO	RGD:1557784	6480464	bisphenol F results in decreased expression of KCP mRNA	CTD	PMID:38685157
Kcp	Rat	cadmium dichloride	increases expression	ISO	RGD:1601689	6480464	Cadmium Chloride results in increased expression of KCP mRNA	CTD	PMID:26472689\|PMID:38568856
Kcp	Rat	carbon nanotube	decreases expression	ISO	RGD:1557784	6480464	Nanotubes, Carbon analog results in decreased expression of KCP mRNA; Nanotubes, Carbon results in decreased more ...	CTD	PMID:25620056
Kcp	Rat	chlorpyrifos	increases expression	ISO	RGD:1557784	6480464	Chlorpyrifos results in increased expression of KCP mRNA	CTD	PMID:37019170
Kcp	Rat	cisplatin	multiple interactions	ISO	RGD:1601689	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of KCP mRNA	CTD	PMID:27392435
Kcp	Rat	Cuprizon	decreases expression	EXP		6480464	Cuprizone results in decreased expression of KCP mRNA	CTD	PMID:26577399
Kcp	Rat	dorsomorphin	multiple interactions	ISO	RGD:1601689	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kcp	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of KCP mRNA	CTD	PMID:29391264
Kcp	Rat	epichlorohydrin	affects response to substance	ISO	RGD:1601689	6480464	KCP gene SNP affects the susceptibility to Epichlorohydrin	CTD	PMID:25622337
Kcp	Rat	formaldehyde	increases expression	ISO	RGD:1601689	6480464	Formaldehyde results in increased expression of KCP mRNA	CTD	PMID:23649840
Kcp	Rat	glyphosate	affects methylation	ISO	RGD:1601689	6480464	Glyphosate affects the methylation of KCP gene	CTD	PMID:35377194
Kcp	Rat	Nutlin-3	multiple interactions	ISO	RGD:1601689	6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of KCP mRNA	CTD	PMID:38460933
Kcp	Rat	paracetamol	decreases expression	ISO	RGD:1601689	6480464	Acetaminophen results in decreased expression of KCP mRNA	CTD	PMID:22230336
Kcp	Rat	phenylmercury acetate	decreases expression	ISO	RGD:1601689	6480464	Phenylmercuric Acetate results in decreased expression of KCP mRNA	CTD	PMID:26272509
Kcp	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1601689	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kcp	Rat	resveratrol	multiple interactions	ISO	RGD:1601689	6480464	[Plant Extracts co-treated with Resveratrol] results in decreased expression of KCP mRNA	CTD	PMID:23557933
Kcp	Rat	SB 431542	multiple interactions	ISO	RGD:1601689	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kcp	Rat	sodium arsenite	increases expression	ISO	RGD:1601689	6480464	sodium arsenite results in increased expression of KCP mRNA	CTD	PMID:38568856
Kcp	Rat	sodium arsenite	increases expression	ISO	RGD:1557784	6480464	sodium arsenite results in increased expression of KCP mRNA	CTD	PMID:37682722
Kcp	Rat	sodium arsenite	decreases expression	ISO	RGD:1601689	6480464	sodium arsenite results in decreased expression of KCP mRNA	CTD	PMID:34032870
Kcp	Rat	sodium fluoride	increases expression	ISO	RGD:1557784	6480464	Sodium Fluoride results in increased expression of KCP protein	CTD	PMID:28918527
Kcp	Rat	tetrachloroethene	decreases expression	ISO	RGD:1557784	6480464	Tetrachloroethylene results in decreased expression of KCP mRNA	CTD	PMID:28973375
Kcp	Rat	titanium dioxide	decreases methylation	ISO	RGD:1557784	6480464	titanium dioxide results in decreased methylation of KCP gene	CTD	PMID:35295148
Kcp	Rat	triptonide	increases expression	ISO	RGD:1557784	6480464	triptonide results in increased expression of KCP mRNA	CTD	PMID:33045310
Kcp	Rat	valproic acid	increases methylation	ISO	RGD:1601689	6480464	Valproic Acid results in increased methylation of KCP gene	CTD	PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcp	Rat	hematopoietic progenitor cell differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q3U492\|ensembl:ENSMUSP00000099135	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcp	Rat	hematopoietic progenitor cell differentiation	acts_upstream_of_or_within	ISO	RGD:1557784	1624291	MGI:1343184 PMID:24029230	RGD	PMID:24029230
Kcp	Rat	positive regulation of BMP signaling pathway	acts_upstream_of_or_within	ISO	RGD:1557784	1624291	PMID:15793581	RGD	PMID:15793581
Kcp	Rat	positive regulation of BMP signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q3U492\|ensembl:ENSMUSP00000099135	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcp	Rat	positive regulation of BMP signaling pathway	involved_in	IBA	MGI:2141640\|PANTHER:PTN001682784	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcp	Rat	extracellular region	is_active_in	IBA	FB:FBgn0000395\|FB:FBgn0039257\|MGI:2141640\|PANTHER:PTN005316910	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kcp	Rat	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcp	Rat	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kcp	Rat	extracellular space	located_in	IEA	UniProtKB:Q3U492\|ensembl:ENSMUSP00000099135	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcp	Rat	extracellular space	located_in	ISO	RGD:1557784	1624291	PMID:15793581	RGD	PMID:15793581

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcp	Rat	protein binding	enables	ISO	RGD:1557784	1624291	PR:P23359 PMID:15793581	RGD	PMID:15793581

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:15793581	PMID:24029230

Kcp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	59,048,209 - 59,083,522 (-)	NCBI		GRCr8
mRatBN7.2	4	58,082,856 - 58,118,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	58,082,857 - 58,109,768 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	56,750,782 - 56,796,878 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	56,760,220 - 56,786,754 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	56,527,313 - 56,562,303 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	56,362,648 - 56,389,182 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	53,181,654 - 53,227,746 (-)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

KCP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	128,876,865 - 128,910,709 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	128,862,042 - 128,910,719 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	128,516,919 - 128,550,763 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	128,318,191 - 128,337,966 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	123,313,433 - 123,347,287 (-)	NCBI		Celera
Cytogenetic Map	7	q32.1	NCBI
HuRef	7	122,878,556 - 122,912,025 (-)	NCBI		HuRef
CHM1_1	7	128,450,213 - 128,484,063 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	130,189,791 - 130,223,635 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	127,900,664 - 127,934,517 (-)	NCBI

Kcp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	29,473,161 - 29,508,006 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	29,473,161 - 29,507,951 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	29,473,162 - 29,508,003 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	29,473,162 - 29,507,952 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	29,432,036 - 29,457,934 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	29,432,046 - 29,457,947 (-)	NCBI		MGSCv36	mm8
Celera	6	29,489,910 - 29,515,855 (-)	NCBI		Celera
Cytogenetic Map	6	A3.3	NCBI
cM Map	6	12.36	NCBI

Kcp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955479	9,670,430 - 9,727,275 (-)	NCBI	ChiLan1.0	ChiLan1.0

KCP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	165,681,441 - 165,715,574 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	17,691,544 - 17,725,820 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	120,822,442 - 120,861,638 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	133,353,386 - 133,387,202 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	133,353,558 - 133,387,170 (-)	Ensembl	panpan1.1		panPan2

KCP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	7,752,162 - 7,776,428 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	7,751,351 - 7,780,558 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	7,439,042 - 7,463,109 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	7,518,053 - 7,542,127 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	7,519,264 - 7,542,588 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	7,723,081 - 7,747,150 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	7,465,097 - 7,489,152 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	7,610,499 - 7,634,756 (+)	NCBI		UU_Cfam_GSD_1.0

Kcp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	54,677,380 - 54,702,823 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936479	15,801,380 - 15,826,461 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936479	15,801,196 - 15,826,461 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	19,711,112 - 19,741,637 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	19,689,111 - 19,741,641 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	20,758,697 - 20,811,227 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	97,479,087 - 97,510,949 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666042	5,891,814 - 5,929,350 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624783	7,290,663 - 7,316,866 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Kcp
109 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	140
Count of miRNA genes:	106
Interacting mature miRNAs:	112
Transcripts:	ENSRNOT00000050644, ENSRNOT00000050795
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	14678065	59678065	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	56647776	78882945	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	40433388	85433388	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	43457976	88457976	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	56647776	78882945	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	26775591	168368347	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	39524264	74726312	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	57114432	81266970	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	57486946	102486946	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	10814170	91360527	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114705	78881294	Rat
2313401	Anxrr27	Anxiety related response QTL 27			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	4	17933508	62933508	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	26907285	75585128	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	34430484	82490359	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	39505275	73892441	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	40433414	85433414	Rat
61412	Pia2	Pristane induced arthritis QTL 2	3.9		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	4	21333343	62278020	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	29494195	81006281	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5214602	78882945	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
7387227	Uae40	Urinary albumin excretion QTL 40	2.9	0.0052	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	17946999	62946999	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	26907285	75585128	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5218294	65958103	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114432	91360801	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	56647776	78882945	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	56647776	78882945	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	XM_008762841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010065769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000050795 ⟹ ENSRNOP00000043530

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	58,082,857 - 58,109,768 (-)	Ensembl
Rnor_6.0 Ensembl	4	56,760,220 - 56,786,754 (-)	Ensembl

RefSeq Acc Id:

XM_017592967 ⟹ XP_017448456

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,118,170 (-)	NCBI
Rnor_6.0	4	56,760,152 - 56,796,878 (-)	NCBI

Sequence:

show sequence

TCTCTCTCTCTCAGAACTGTAGTTGAATTTGACTGTAAGTAAACTAAAAATAAAAGTTTCATGTATCCCAGGCTGGCTCAAACTTGTCTGTTTCTGGGTGCTAAGAATGGAGATTGGTATCACCATCC
GTGGCTCGGGGCTGGCAAACCCAGGTCTTCATGCGAGTAGGGCAAACGCACAACTGAGCTGGTACAGCCTCATCCCTAAAGATGGAATTGGAAGAAATTTAAGTCAGGCAATATTTAAGTACACACTT
GTACTTCCAGCATTTGGGAGATAAAGGCCAAAACCAAAGCCAAGGTTTGGCTGCATGAGACCGTGCCTCAAAAAGAAAAGGAAAAGGAGAAGGAAGAGGAAGGAAGAGGAGGTGGGAAGTTTAAAAAG
ATGAAAATAATTCTACCTGGCTTCTCTGTATTAGGCCCCAACTTGCCTCCCCATGACTCCCTCCTCCAGGATTCCCAGGACTCTTGAATGCTCAGCTTTAGCCAAGCTGAGGTCTTAGAAGGACATGG
GTGACATTGAACAGAGGTTAGCTTTGTAAAGGGGACATCCACAAAGGCATGACCAGGGAAACAAAAGGCATTTTGGAGATGCCACCAGTGTGAGACAGCCCTCCCTCAGAAAGGCTGCCCTCGGGACC
TGGGCTACACCAGGTGTGGGCAGAAGAAAGGATCCCCAAGTGCTCCCTTCTTTTGAGTTCCTAACTCTCGCCAGACCTTGAACCCACAGAGCACCTTGTCATACAGGCCAGGTGATTACCTGTTTTGA
GTAAGAGTAAGGCAGGAAAGGTCATAGGGCAGCACAGGAAGGGGTGTCAGATAGAGAAGCTGAAACTACATAGGGAGACCCCCTTAAGACCCATGGCTACCCCAAGTTTCACCCCACCAAAGCCAAAG
ATGCCAGCTTTTTGCAGGCTAGGAGTCCCTGACTGGATGATAAGGTTGTGAGTGGGTGAAAAGCTGCTGATTGTCGAAGGCTCTAAGAACCAGATGAGTAGTTTCCCAGGATTCCCAGCCTTTCAGGT
CATCAGGGACACTTTTCTGAGGACTCACTTCTGGGTCACATATAAATTGTGGACACGAGAAGGGATCAGGGTGGAATGGGGACCAGGACACCTGCATCAGTTGCTTATCTGTTTCTATGACCCAGTAT
GGGGCGATTCGAAGGCATAGTTGGTCATGGTGGGGAAGGTGTAGCGGTTTCAAGTGACTACGATCTCACTGCATCTGCAGGCAGGGGGCAGAGAGAAATGAATGCCTGTGTGCCCTCATTGCCTGTTT
TTATTTAGTCTGGGAACCCAGCACATGGGATGATGCCCCCACATTTGGGGCAGATCTTCCCTCCTTAGTTAAGCCTCTCCGGAAACACCGCCATACAAACATCTGGAGATATGCTTCTAAATCCAATC
AATTTAACAATAAAGATGGGCCACCACAGTACCCCTGCTGGACCCTGCGGAACCTGCAAGCCCTTCCTGGACACCTCCCCAAAGGATGGGTCCCTGAGAATTGCCTTCTTCATCTGGGCTACTCAGGA
ATACAGACTGAGTTTCTGGGACACAGTTGGGTGTCAGCTCCTCAGGAGATGGGAGGGACAGCTGTGTGCAGAACTATTGATCCGTGGTTAGAGTGGTGCGCATGTGCAAGGCAGCGGCTGAATTCCTT
CGTGCACGCGCCCCCTGCTGGGAAGAGCTGGGAATGACCAGAAGTATTTTCAGGTTGCCATGGAGACAGAGCTGGTTGGCAGCGCGTCTGACTGAGACTGACTTGTCTCCTGCCCGTGGTGGGATAGA
GATGGAACTGGCACAGTGATGGCACCACCACAAGCCCTGGTCTGCTTAGGTGCCTGCTCTGGGGACGAGAGCCTGAACATGCAGCTGTGTGAAGTCCATCCATCAAGGCAAGCTTGGTCGGGAACTCC
TGATGACTGCCCTGACTTCCCCAGCGGTTTCTGCCGGGTGTTGAGGAGGAACCTGAGAAGAGAAGTTTTAGCATCCAAGGTCACTTGGAAGCGCCTCAGAGCACAGACTTACCGCGAGGCGGGTCGAG
CGAGCATGGCGGGGGCTCGGGCGGCGCTGCTACTGCTGCTGCTGCTCCTGCACCTCTGGAACCTGGCGCTGGCCGCGCGGGGTGGAGAGGTCTCCAAAGGGCAGCCTAGACTTGCTGATGTCCTTGAG
TCTCAGCAGCAGGCCCCCTCCCACTCCTTGGTCCCTTGTGAGACCCAACAGCAGCAGTTATGCCCCCTGGAGGAGAGGCTGGAACGGCTGGAGGCAGACGTGACTTACCTCAGAAAGCAGAACAGGGA
CCTGCAAGCCAGGCTGCTGCAGCTGGAGTCCTGCAAGTGCTGCTCAACCTCCCCCCAGTGCTGGGGGCCAGGTCACCCCTGTCCTGAAGGAGCTCGCTGGGAGCCTGATGCCTGCACGGCCTGCGTGT
GCCGTGATGGGACCACGCACTGTGGCCCCCAGCCCAACCTGCCCCACTGCCGTGGCTGCAGCCACAATGGGCAGTCTTATGGTCATGGGGAGACCTTCTCCCCAGATGCTTGTACCACCTGCCGCTGT
CTGGCAGGAGCTGTGCAGTGCCAGGGGCCTTCCTGCTCTGAGCTCAACTGTCTGGAGAGCTTCACCCCGCCTGGAGAATGCTGCCCCATCTGCCGGCCAGGCTGTGAGTACGAGGGGCAGCTTCACCA
GGAAGGGACCAGCTTCCTGTCCACTTCCAACCCATGCCTCCAGTGTTCTTGCCTGAGGAGCCTGGTTCGGTGTGTGCCTGTGAAGTGCCAGCCAAGCCCCTGCCCCAACCCAGTCCTGAGACCTGGAC
ACTGCTGCCCAGTCTGCCAAGCCTCCGGCTGCACAGAAGGTCACTCTCACAGGGACCATGGCCAAGAGTGGACCACTCCTGGAGACCCCTGCCGCATCTGCCAGTGCCTGGAGGGGCACATCCAGTGC
CGCCAGCAGGAGTGTGCCAGTCTTTGTCCATACCCTGCCAGGCCCCTTCCGGGTACCTGCTGCCCAGTGTGTGACGGCTGTTTCCTAAATGGGCGGGAGCACAGCAGTGGGGAGCCCGTGGGCTCCCA
GGACCCCTGCTCCAGCTGCCACTGTGCTAATGGGAGTGTCCAGTGTGAGCCTCTGCCCTGCCCGCCTGCACCCTGCAGATATCCGGGCAGGATCCCCGGGCAATGCTGCCCTGTCTGTGATGGCTGTA
AATACCAGGGACATGAATATCGGAGCCAGGAGACCTTTACCCTCCAAGAGAATGGCCGCTGCCTTCGGTGCACCTGCCAGGCTGGTGAAGTATCCTGTGAGGAACAGGACTGCCCGGTCACCCCCTGT
GTCCACACTGCCTCCGGCCCCCAGCTCTGCTCAGCCTGTGTGCTCAATGGTGAGGAGTTTGCTGAGGGGATCCAGTGGGAGCCAGATGACCAGCCCTGTACTACCTGTTCCTGCCAAGACGGAGTGCC
TGTGTGCAGGGCTGCACTTTGCTCTCCAGTACCCTGCCAACATCCTACCCAGCCGCCCGGTGCCTGCTGCCCCAGCTGTGAGAGCTGCACCTACCACGGCCTAGTGTATTCTAATGGGCAGAACTTCA
CAGATGTGGACAGCCCTTGTCAGACCTGCTACTGTGAGGATGGGACTGTGAGGTGTTCGGTGATCAACTGTCCTTCCCTGACCTGTGCCAAGCCCCAGAATGGACCAGGCCAGTGCTGCCCCAAGTGC
CCAGACTGCATCCTGGAGGCACAGATGTTTGTAGATGGGGAGCGCTTTCCTCATCCAAGAGACCCCTGCCAGGAGTGCCTGTGTCAGGAAGGCCAGACTCACTGCCAGCTCCGAGCCTGCCACAGCGC
CCCCTGTGGTCACCCTCTGCCAAGCACCTGCTGCAGGAATGACTGCAAAGGCTGTGCCTTTGGCGGGAAAGAGTACCTCAACGGAGCAGACTTCCCGCATCCCACTGATCCGTGTCGCATGTGTCGCT
GTCTGAGCGGCAATGTACAATGCCTGGCGCGTCGCTGTCCGCCACTGGCCTGTCCGCAGCCAGTCCTCACTCCGGGAGACTGCTGCCCTCAGTGCCCCGATGCCCCTGCTGGCTGCCCACAGTCAGGG
AATACGGTCCTTGTCCGCCACCAGGAGCACTTTTTCCAACCGGGAGACCCCTGCAGCCGCTGCCTCTGCCTGGACGGCTCCGTGTCCTGCCAGCGACTGCCCTGTCCTCCTGCTCCCTGTGCCCACCC
GCGCCAGGGCGCCTGTTGCCCCTCTTGCGACGGCTGCCTGTATCATGGGAAGGAGTTTGCCAATGGAGAACGATTTCCATCACCTAGTGTCACGTGCCACGTGTGCCTCTGCTGGGAAGGCAGCGTCA
ACTGCGAGCCCAGGGCTTGTGCCCCTGCACAGTGCCCATTTCCCACCAGGGAAGATTGCTGTCCTGCCTGTGATAGCTGTGAGTATTTGGGGGTATCCTATCTGAACAGCCAGGAGTTCCCAGACCCC
CGGGAAGCCTGCAACCTGTGCACCTGCCTTGGAGGCTTTGTGACTTGCACCCGCCGGCCCTGCGAGCCTCCAGCCTGCAGCCACCCACTCATCTTACCGAAGCACTGCTGTCCAACCTGCCAGGGATG
CCTGTACCACGGAATCACCGCTGCCCTCGGAGAGACCCTTCCTGATCCTCTTGACCCCACCTGCTCCCTCTGCACCTGTGAGGAAGGTTCTATGCGCTGTCACAAGAAACCATGTCCTCCGGCTCTCT
GCACACACCCTTCTCCAGGCCCCTGTTTCTGCCCTGTGTGTCGCAGCTGCCTCTTTCAGGGCCAGGAGCACCAAGACGGGGAGGAGTTCGAGGGACCTGAGGGCAGCTGTGAGCGCTGCCGCTGTCTG
GCTGGCCAGGTCAGCTGTATGAGGCTCCAGTGCCCGCCTCTGCCCTGCTTGCTTCAGGCCACAGAACCAGGCACCTGTTGTCCTCGATGCACAGGCTGCCGCGTTCGTGGGGAGGAGCATCCTGAAGG
TAGTAGCTGGGTGCCGGCGGACAGCCCCTGTTCTTCCTGCATGTGTCACAAGGGCATTGTCACTTGTGCCCAAGTCCAGTGTGTCAGCGCCTGCATCTGGCCCCAGCAGGGGCCCAGTGACTGCTGCC
CTTCATGCTCTGGCTGTGAGCATGAGGGCAGAAAGTACGAACCCGGGGAGAGCTTCCAACCTGGGGACGACCCATGTGAAGTGTGCATCTGCGAGCTGAAGGGCAAGGGGCCTCCCAGCCTGCACTGT
CGCCGGCGCCAGTGCCCCAGTCTGGTGGGCTGCCCACCAAGCCAGCTACTTCCTCCTGGCCCCCAGCACTGCTGCCCTGCCTGTGCCCAGGCACTGAGTAACTGCACAGAGGACCTGCTGGGGTCTGA
GCTGGTGCCACCAGACCCCTGCTACACCTGCCAGTGTCAGGATCTGACATGGCTCTGTACTCACCGGGCCTGTCCTGCGCTCAGCTGTCCCCTGTGGGAGCACCACACAACCCCTGGGAGCTGCTGCC
CCGTGTGTAAAGACCCTACCGGATCATGCTCGCACCAGGGTCGCTGGGTGGCCTCTGGAGAACACTGGATAGTGGACGCCTGCACCAGCTGTGCCTGTGTGGCTGGTACTGTGCACTGCCAGAGCCAG
CGCTGCAGGAACCTCTCATGTGGCCGGGATGAGGTCCCTGCCCTGAGTCCCGGCAGCTGCTGTCCCCGCTGTTTGCCCGGGCTGGCTTCCTGCATGGCCTTCGGAGACCCCCATTACCGCACCTTCGA
TGGCCGCCTGCTGCACTTCCAGGGCAGCTGCAGCTACGTGCTGGCCAAGGACTGCCACAGCGAGGACTTCAGTGTGCACGTGACTAATGATGACCGGGGCCGGAGGGGTGTGGCCTGGACCCAAGAGG
TAGCGGTGCTGTTGGGAACCGTGGCTGTGAGGCTGCTGCAAGGCAGGACAGTCATGGTGGACCAGCACACGGTGACCTTGCCCTTCCTTCGGGAGCCACTGCTGTACATTGAGCTTCGTGGTCACACC
GTGATCCTGCATGCCCAGCCTGGGCTTCAGGTGCTGTGGGACGGGCAATCCCAGGTGGAGGTGAGAGTTCCCAGCTCCTACCGGGGCCAGACCTGTGGCCTCTGTGGGAACTTCAATGGCTTTGCCCA
GGACGATCTGCAGGGTCCGGATGGGAGGCTCCTGCCCACAGAGGCTGCATTTGGGAACAGCTGGAAGGTCCCCAAGGGGCTGGGGCCTGGCCGGCCATGTTCTGCAGGCCGAGAGGTGGACCCCTGCC
GGGCAGCAGGCTACCGTGCCAGACGTGAGGCCAATGCCCGGTGCGGGATCCTGAAGTCTTCACCGTTCAGTCGCTGCCATGCTGTGGTGCCACCAGAACCCTTCTTTGCCGCCTGTGTGTATGACCTG
TGTGCTTGTGGGCCAGGCTCCTCAGCTGATACCTGTCTCTGTGATGCCCTTGAAGCCTATGCTAGCCACTGTCGCCAGGCTGGGGTGACTCCTGTCTGGAGGGGCCCTACACTCTGTGTGGTGGGCTG
CCCTGTGGAACGTGGCTTTGTGTTTGATGAGTGTGGACCGCCTTGTCCCCGTACCTGTTTCAACCAGCACATACCCCTAGGGGAGCTGGCAGCCCACTGCGTGAGGCCCTGTGTTCCAGGCTGCCAGT
GTCCTGCAGGCCTGGTGGAGCATGAAGGCCATTGCATCTCACCTGAGGCCTGCCCATCAGTCCTGCTTACTGGAGGCTAGCCAGCTCGCATGCTGTCCACTCCCAGTCAGGAGCAGCCTCTGGGTCCA
CCCTGAGTTAAGAACACCCT

hide sequence

RefSeq Acc Id:

XM_039108993 ⟹ XP_038964921

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XM_039108995 ⟹ XP_038964923

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XM_039108996 ⟹ XP_038964924

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,083,439 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,118,083 (-)	NCBI

RefSeq Acc Id:

XM_039108999 ⟹ XP_038964927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,069,783 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,104,694 (-)	NCBI

RefSeq Acc Id:

XM_039109000 ⟹ XP_038964928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,069,783 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,104,694 (-)	NCBI

RefSeq Acc Id:

XM_039109001 ⟹ XP_038964929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,069,955 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,104,694 (-)	NCBI

RefSeq Acc Id:

XM_039109004 ⟹ XP_038964932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,054,669 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,089,317 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XM_039109005 ⟹ XP_038964933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,064,715 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,099,362 (-)	NCBI

RefSeq Acc Id:

XM_039109007 ⟹ XP_038964935

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,048,209 - 59,063,665 (-)	NCBI
mRatBN7.2	4	58,082,856 - 58,098,315 (-)	NCBI

RefSeq Acc Id:

XR_005504136

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,050,513 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,085,161 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XR_005504137

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,050,513 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,085,161 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XR_005504138

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,052,534 - 59,083,520 (-)	NCBI
mRatBN7.2	4	58,087,181 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XR_005504140

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,059,985 - 59,083,522 (-)	NCBI
mRatBN7.2	4	58,094,633 - 58,118,170 (-)	NCBI

RefSeq Acc Id:

XR_010065769

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	59,052,534 - 59,083,520 (-)	NCBI


Protein RefSeqs	XP_017448456	(Get FASTA)	NCBI Sequence Viewer
	XP_038964921	(Get FASTA)	NCBI Sequence Viewer
	XP_038964923	(Get FASTA)	NCBI Sequence Viewer
	XP_038964924	(Get FASTA)	NCBI Sequence Viewer
	XP_038964927	(Get FASTA)	NCBI Sequence Viewer
	XP_038964928	(Get FASTA)	NCBI Sequence Viewer
	XP_038964929	(Get FASTA)	NCBI Sequence Viewer
	XP_038964932	(Get FASTA)	NCBI Sequence Viewer
	XP_038964933	(Get FASTA)	NCBI Sequence Viewer
	XP_038964935	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043530
	ENSRNOP00000043530.5

RefSeq Acc Id:	XP_017448456 ⟸ XM_017592967
- Peptide Label:	isoform X4
- UniProtKB:	D3ZGP6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPPQALVCLGACSGDESLNMQLCEVHPSRQAWSGTPDDCPDFPSGFCRVLRRNLRREVLASKVTWKRLRAQTYREAGRASMAGARAALLLLLLLLHLWNLALAARGGEVSKGQPRLADVLESQQQAP SHSLVPCETQQQQLCPLEERLERLEADVTYLRKQNRDLQARLLQLESCKCCSTSPQCWGPGHPCPEGARWEPDACTACVCRDGTTHCGPQPNLPHCRGCSHNGQSYGHGETFSPDACTTCRCLAGAVQ CQGPSCSELNCLESFTPPGECCPICRPGCEYEGQLHQEGTSFLSTSNPCLQCSCLRSLVRCVPVKCQPSPCPNPVLRPGHCCPVCQASGCTEGHSHRDHGQEWTTPGDPCRICQCLEGHIQCRQQECA SLCPYPARPLPGTCCPVCDGCFLNGREHSSGEPVGSQDPCSSCHCANGSVQCEPLPCPPAPCRYPGRIPGQCCPVCDGCKYQGHEYRSQETFTLQENGRCLRCTCQAGEVSCEEQDCPVTPCVHTASG PQLCSACVLNGEEFAEGIQWEPDDQPCTTCSCQDGVPVCRAALCSPVPCQHPTQPPGACCPSCESCTYHGLVYSNGQNFTDVDSPCQTCYCEDGTVRCSVINCPSLTCAKPQNGPGQCCPKCPDCILE AQMFVDGERFPHPRDPCQECLCQEGQTHCQLRACHSAPCGHPLPSTCCRNDCKGCAFGGKEYLNGADFPHPTDPCRMCRCLSGNVQCLARRCPPLACPQPVLTPGDCCPQCPDAPAGCPQSGNTVLVR HQEHFFQPGDPCSRCLCLDGSVSCQRLPCPPAPCAHPRQGACCPSCDGCLYHGKEFANGERFPSPSVTCHVCLCWEGSVNCEPRACAPAQCPFPTREDCCPACDSCEYLGVSYLNSQEFPDPREACNL CTCLGGFVTCTRRPCEPPACSHPLILPKHCCPTCQGCLYHGITAALGETLPDPLDPTCSLCTCEEGSMRCHKKPCPPALCTHPSPGPCFCPVCRSCLFQGQEHQDGEEFEGPEGSCERCRCLAGQVSC MRLQCPPLPCLLQATEPGTCCPRCTGCRVRGEEHPEGSSWVPADSPCSSCMCHKGIVTCAQVQCVSACIWPQQGPSDCCPSCSGCEHEGRKYEPGESFQPGDDPCEVCICELKGKGPPSLHCRRRQCP SLVGCPPSQLLPPGPQHCCPACAQALSNCTEDLLGSELVPPDPCYTCQCQDLTWLCTHRACPALSCPLWEHHTTPGSCCPVCKDPTGSCSHQGRWVASGEHWIVDACTSCACVAGTVHCQSQRCRNLS CGRDEVPALSPGSCCPRCLPGLASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSEDFSVHVTNDDRGRRGVAWTQEVAVLLGTVAVRLLQGRTVMVDQHTVTLPFLREPLLYIELRGHTVILHAQ PGLQVLWDGQSQVEVRVPSSYRGQTCGLCGNFNGFAQDDLQGPDGRLLPTEAAFGNSWKVPKGLGPGRPCSAGREVDPCRAAGYRARREANARCGILKSSPFSRCHAVVPPEPFFAACVYDLCACGPG SSADTCLCDALEAYASHCRQAGVTPVWRGPTLCVVGCPVERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEGHCISPEACPSVLLTGG hide sequence

Ensembl Acc Id:

ENSRNOP00000043530 ⟸ ENSRNOT00000050795

RefSeq Acc Id:	XP_038964923 ⟸ XM_039108995
- Peptide Label:	isoform X2
- UniProtKB:	D3ZGP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038964921 ⟸ XM_039108993
- Peptide Label:	isoform X1
- UniProtKB:	D3ZGP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038964924 ⟸ XM_039108996
- Peptide Label:	isoform X3
- UniProtKB:	D3ZGP6 (UniProtKB/TrEMBL)

Protein Domains

VWFC VWFD

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZGP6-F1-model_v2	AlphaFold	D3ZGP6	1-1552	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-45391	BioCyc
Ensembl Genes	ENSRNOG00000021855	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000050795	ENTREZGENE
	ENSRNOT00000050795.6	UniProtKB/TrEMBL
Gene3D-CATH	6.20.200.20	UniProtKB/TrEMBL
	Complement Module, domain 1	UniProtKB/TrEMBL
InterPro	Kielin_Chordin-BMP_Reg	UniProtKB/TrEMBL
	Ser_inhib-like_sf	UniProtKB/TrEMBL
	Unchr_dom_Cys-rich	UniProtKB/TrEMBL
	von_Willebrand_fac_D	UniProtKB/TrEMBL
	VWF_C	UniProtKB/TrEMBL
NCBI Gene	296952	ENTREZGENE
PANTHER	CROSSVEINLESS 2	UniProtKB/TrEMBL
	KIELIN_CHORDIN-LIKE PROTEIN	UniProtKB/TrEMBL
Pfam	VWC	UniProtKB/TrEMBL
	VWD	UniProtKB/TrEMBL
PhenoGen	Kcp	PhenoGen
PROSITE	VWFC_1	UniProtKB/TrEMBL
	VWFC_2	UniProtKB/TrEMBL
	VWFD	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000021855	RatGTEx
SMART	SM00832	UniProtKB/TrEMBL
	VWC	UniProtKB/TrEMBL
	VWC_out	UniProtKB/TrEMBL
	VWD	UniProtKB/TrEMBL
Superfamily-SCOP	Cysrich_TIL	UniProtKB/TrEMBL
	FnI-like domain	UniProtKB/TrEMBL
UniProt	D3ZGP6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-21	Kcp	kielin cysteine rich BMP regulator	Kcp	kielin/chordin-like protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-29	Kcp	kielin/chordin-like protein	LOC102555244	involucrin-like	Data merged from RGD:7663438	737654	PROVISIONAL
2013-12-18	LOC102555244	involucrin-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2009-02-23	Kcp	kielin/chordin-like protein	Crim2	cysteine rich BMP regulator 2 (chordin like)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Crim2	cysteine rich BMP regulator 2 (chordin like)	RGD1561119_predicted	similar to kielin-like (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561119_predicted	similar to kielin-like (predicted)	LOC296952	similar to kielin-like	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC296952	similar to kielin-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar