Smchd1 (SMC hinge domain containing 1) - Rat Genome Database

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Gene: Smchd1 (SMC hinge domain containing 1) Mus musculus
Analyze
Symbol: Smchd1
Name: SMC hinge domain containing 1
RGD ID: 1553193
MGI Page MGI
Description: Enables ATP hydrolysis activity and protein homodimerization activity. Acts upstream of or within inactivation of paternal X chromosome by genomic imprinting. Located in Barr body. Is expressed in several structures, including blastocyst and genitourinary system. Human ortholog(s) of this gene implicated in facioscapulohumeral muscular dystrophy 2. Orthologous to human SMCHD1 (structural maintenance of chromosomes flexible hinge domain containing 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4931400A14Rik; AW554188; ENSMUSG00000041913; mKIAA0650; MommeD; MommeD1; predicted gene, ENSMUSG00000041913; SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,651,484 - 71,782,361 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,651,484 - 71,782,338 (-)EnsemblGRCm39 Ensembl
GRCm381771,344,489 - 71,475,366 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1771,344,489 - 71,475,343 (-)EnsemblGRCm38mm10GRCm38
MGSCv371771,693,829 - 71,824,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361771,249,789 - 71,332,381 (-)NCBIMGSCv36mm8
Celera1775,615,403 - 75,745,635 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Aug 31;10(4):167-80.
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14691545   PMID:15782199   PMID:15890782   PMID:16141072  
PMID:16141073   PMID:18287559   PMID:18425126   PMID:18799693   PMID:19334288   PMID:21267068   PMID:21553025   PMID:21873635   PMID:22083510   PMID:22841499   PMID:22922362   PMID:23269277  
PMID:23754746   PMID:24025402   PMID:24457600   PMID:24818964   PMID:26091879   PMID:26391951   PMID:26496610   PMID:26733688   PMID:26981392   PMID:27059856   PMID:29281018   PMID:29748383  
PMID:29900695   PMID:30126901   PMID:30127357   PMID:30428357   PMID:30457570   PMID:30604745   PMID:30970248   PMID:31040226   PMID:31270318   PMID:31365290   PMID:31420322   PMID:32325033  
PMID:32546545   PMID:33004076   PMID:33186096   PMID:33523915   PMID:35831949   PMID:35843975   PMID:35879318   PMID:37253089   PMID:37749075   PMID:38355793  


Genomics

Comparative Map Data
Smchd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,651,484 - 71,782,361 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,651,484 - 71,782,338 (-)EnsemblGRCm39 Ensembl
GRCm381771,344,489 - 71,475,366 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1771,344,489 - 71,475,343 (-)EnsemblGRCm38mm10GRCm38
MGSCv371771,693,829 - 71,824,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361771,249,789 - 71,332,381 (-)NCBIMGSCv36mm8
Celera1775,615,403 - 75,745,635 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
SMCHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38182,655,726 - 2,805,017 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl182,655,726 - 2,805,017 (+)EnsemblGRCh38hg38GRCh38
GRCh37182,655,725 - 2,805,015 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36182,645,886 - 2,795,015 (+)NCBINCBI36Build 36hg18NCBI36
Celera182,531,141 - 2,680,454 (+)NCBICelera
Cytogenetic Map18p11.32NCBI
HuRef182,617,276 - 2,766,445 (+)NCBIHuRef
CHM1_1182,655,260 - 2,804,386 (+)NCBICHM1_1
T2T-CHM13v2.0182,811,308 - 2,960,649 (+)NCBIT2T-CHM13v2.0
Smchd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,690,050 - 118,837,281 (-)NCBIGRCr8
mRatBN7.29111,243,445 - 111,387,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9111,247,702 - 111,349,665 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.09119,675,750 - 119,818,620 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,676,628 - 119,818,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09119,128,945 - 119,272,041 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49110,535,987 - 110,680,034 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19110,753,793 - 110,888,830 (-)NCBI
Celera9108,371,971 - 108,513,633 (-)NCBICelera
Cytogenetic Map9q38NCBI
Smchd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554027,544,265 - 7,649,067 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554027,544,265 - 7,661,191 (-)NCBIChiLan1.0ChiLan1.0
SMCHD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21735,641,467 - 35,790,813 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11821,334,059 - 21,483,403 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01811,479,742 - 11,627,035 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11813,785,912 - 13,933,889 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1813,785,912 - 13,933,887 (-)Ensemblpanpan1.1panPan2
SMCHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1769,359,286 - 69,505,067 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl769,358,447 - 69,621,067 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha768,814,232 - 68,960,329 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0769,420,889 - 69,567,321 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl769,420,904 - 69,565,345 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1769,103,483 - 69,249,691 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0769,123,627 - 69,269,690 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0769,420,839 - 69,567,137 (+)NCBIUU_Cfam_GSD_1.0
Smchd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494465,703,624 - 65,855,869 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366721,685,734 - 1,838,315 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366721,686,070 - 1,838,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMCHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6103,808,066 - 103,965,335 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16103,809,732 - 103,986,057 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2696,820,958 - 96,945,192 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMCHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11861,921,477 - 62,069,187 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1861,921,124 - 62,070,878 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605036,779,796 - 36,928,892 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smchd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477013,000,316 - 13,124,031 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477013,000,532 - 13,123,346 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smchd1
4946 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:659
Count of miRNA genes:472
Interacting mature miRNAs:555
Transcripts:ENSMUST00000127430, ENSMUST00000136071, ENSMUST00000138193, ENSMUST00000147111, ENSMUST00000182049, ENSMUST00000182107, ENSMUST00000182205, ENSMUST00000182747, ENSMUST00000183046
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5753444780885776Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
11565819Ppipq1_mprepulse inhibition percentage QTL 1 (mouse)177105765575377655Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176894131995294699Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
14928308Manh82_mmandible shape 82 (mouse)176631524395294699Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177070119895294699Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177070119895294699Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177070119895294699Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177070119895294699Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse
13464254Ifvrq3_minfluenza virus resistance QTL 3 (mouse)176795765583908089Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse

Markers in Region
AW549786  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381771,458,380 - 71,458,468UniSTSGRCm38
GRCm3810128,089,115 - 128,090,063UniSTSGRCm38
MGSCv371771,807,720 - 71,807,808UniSTSGRCm37
MGSCv3710127,526,171 - 127,527,119UniSTSGRCm37
Celera1775,728,752 - 75,728,840UniSTS
Celera10130,483,851 - 130,484,799UniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map10D3UniSTS
Whitehead/MRC_RH17832.51UniSTS
AW554188  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381771,344,787 - 71,344,936UniSTSGRCm38
MGSCv371771,694,127 - 71,694,276UniSTSGRCm37
Celera1775,615,701 - 75,615,850UniSTS
Cytogenetic Map17E1.3UniSTS
Whitehead/MRC_RH17841.57UniSTS
D17Wsu164e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381771,458,201 - 71,458,436UniSTSGRCm38
MGSCv371771,807,541 - 71,807,776UniSTSGRCm37
Celera1775,728,573 - 75,728,808UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17E1.3UniSTS
cM Map1742.5UniSTS
ATP5B  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381771,459,426 - 71,459,562UniSTSGRCm38
GRCm3810128,084,331 - 128,084,467UniSTSGRCm38
MGSCv371771,808,766 - 71,808,902UniSTSGRCm37
MGSCv3710127,521,387 - 127,521,523UniSTSGRCm37
Celera1775,729,798 - 75,729,934UniSTS
Celera10130,479,068 - 130,479,204UniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map10D3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_028887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC076627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN668845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000127430   ⟹   ENSMUSP00000121835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,651,484 - 71,782,338 (-)Ensembl
GRCm38.p6 Ensembl1771,344,489 - 71,475,343 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,697,476 - 71,698,722 (-)Ensembl
GRCm38.p6 Ensembl1771,390,481 - 71,391,727 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138193
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,651,484 - 71,663,491 (-)Ensembl
GRCm38.p6 Ensembl1771,344,489 - 71,356,496 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147111
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,655,915 - 71,668,954 (-)Ensembl
GRCm38.p6 Ensembl1771,348,920 - 71,361,959 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182049
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,653,505 - 71,656,001 (-)Ensembl
GRCm38.p6 Ensembl1771,346,510 - 71,349,006 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,664,081 - 71,668,187 (-)Ensembl
GRCm38.p6 Ensembl1771,357,086 - 71,361,192 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182205
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,657,872 - 71,660,381 (-)Ensembl
GRCm38.p6 Ensembl1771,350,877 - 71,353,386 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182747
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,779,534 - 71,782,323 (-)Ensembl
GRCm38.p6 Ensembl1771,472,539 - 71,475,328 (-)Ensembl
Ensembl Acc Id: ENSMUST00000183046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,700,900 - 71,701,719 (-)Ensembl
GRCm38.p6 Ensembl1771,393,905 - 71,394,724 (-)Ensembl
Ensembl Acc Id: ENSMUST00000232914
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,682,978 - 71,684,025 (-)Ensembl
GRCm38.p6 Ensembl1771,375,983 - 71,377,030 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233839   ⟹   ENSMUSP00000156815
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,655,881 - 71,667,161 (-)Ensembl
GRCm38.p6 Ensembl1771,348,886 - 71,360,166 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233872   ⟹   ENSMUSP00000156880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1771,755,577 - 71,772,641 (-)Ensembl
GRCm38.p6 Ensembl1771,448,582 - 71,465,646 (-)Ensembl
RefSeq Acc Id: NM_028887   ⟹   NP_083163
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391771,651,484 - 71,782,338 (-)NCBI
GRCm381771,344,489 - 71,475,343 (-)ENTREZGENE
MGSCv371771,693,829 - 71,824,683 (-)RGD
Celera1775,615,403 - 75,745,635 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030250119   ⟹   XP_030105979
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391771,651,484 - 71,782,361 (-)NCBI
GRCm381771,344,489 - 71,475,366 (-)NCBI
Sequence:
RefSeq Acc Id: NP_083163   ⟸   NM_028887
- UniProtKB: Q8BP09 (UniProtKB/Swiss-Prot),   Q811H3 (UniProtKB/Swiss-Prot),   Q6ZQ78 (UniProtKB/Swiss-Prot),   Q6PE93 (UniProtKB/Swiss-Prot),   Q6PDM8 (UniProtKB/Swiss-Prot),   Q9D4M7 (UniProtKB/Swiss-Prot),   Q6P5D8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030105979   ⟸   XM_030250119
- Peptide Label: isoform X1
Ensembl Acc Id: ENSMUSP00000121835   ⟸   ENSMUST00000127430
Ensembl Acc Id: ENSMUSP00000156815   ⟸   ENSMUST00000233839
Ensembl Acc Id: ENSMUSP00000156880   ⟸   ENSMUST00000233872
Protein Domains
SMC hinge

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P5D8-F1-model_v2 AlphaFold Q6P5D8 1-2007 view protein structure

Promoters
RGD ID:13676722
Promoter ID:EPDNEW_M22510
Type:initiation region
Name:Smchd1_1
Description:Mus musculus SMC hinge domain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381771,475,311 - 71,475,371EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921605 AgrOrtholog
Ensembl Genes ENSMUSG00000024054 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000127430 ENTREZGENE
  ENSMUST00000127430.2 UniProtKB/Swiss-Prot
  ENSMUST00000233839.2 UniProtKB/TrEMBL
  ENSMUST00000233872.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1060.20 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/Swiss-Prot
  3.30.70.1620 UniProtKB/TrEMBL
InterPro HATPase_C_sf UniProtKB/Swiss-Prot
  SMC_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMC_hinge_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMCHD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74355 UniProtKB/Swiss-Prot
MGD MGI:1921605 ENTREZGENE
NCBI Gene 74355 ENTREZGENE
PANTHER PTHR22640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/Swiss-Prot
  SMC_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMCHD1_S5 UniProtKB/Swiss-Prot
PharmGKB SMCHD1 RGD
PhenoGen Smchd1 PhenoGen
SMART SMC_hinge UniProtKB/Swiss-Prot
Superfamily-SCOP SSF55874 UniProtKB/Swiss-Prot
  SSF75553 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2W494_MOUSE UniProtKB/TrEMBL
  A0A3B2WD81_MOUSE UniProtKB/TrEMBL
  Q6P5D8 ENTREZGENE
  Q6PDM8 ENTREZGENE
  Q6PE93 ENTREZGENE
  Q6ZQ78 ENTREZGENE
  Q811H3 ENTREZGENE
  Q8BP09 ENTREZGENE
  Q9D4M7 ENTREZGENE
  SMHD1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PDM8 UniProtKB/Swiss-Prot
  Q6PE93 UniProtKB/Swiss-Prot
  Q6ZQ78 UniProtKB/Swiss-Prot
  Q811H3 UniProtKB/Swiss-Prot
  Q8BP09 UniProtKB/Swiss-Prot
  Q9D4M7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-31 Smchd1  SMC hinge domain containing 1  ENSMUSG00000041913  predicted gene, ENSMUSG00000041913  Data merged from RGD:1616894 737654 PROVISIONAL