Or1d2 (olfactory receptor family 1 subfamily D member 2) - Rat Genome Database

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Gene: Or1d2 (olfactory receptor family 1 subfamily D member 2) Mus musculus
Analyze
Symbol: Or1d2
Name: olfactory receptor family 1 subfamily D member 2
RGD ID: 1552293
MGI Page MGI
Description: Predicted to enable identical protein binding activity and olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including OR1D2 (olfactory receptor family 1 subfamily D member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2P1NL-4500587-4501525; MOR127; MOR127-5P; olfactory receptor 412; olfactory receptor MOR127-5P; Olfr412
RGD Orthologs
Human
Rat
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,255,497 - 74,256,435 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,252,895 - 74,257,044 (+)EnsemblGRCm39 Ensembl
GRCm381174,364,671 - 74,365,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,362,069 - 74,366,218 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,178,173 - 74,179,111 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,180,866 - 74,181,804 (+)NCBIMGSCv36mm8
Celera1181,877,216 - 81,878,154 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or1d2Mouseacrylamide increases expressionISOOr1d2 (Rattus norvegicus)6480464Acrylamide results in increased expression of OR1D2 mRNACTDPMID:28959563
Or1d2Mouseaflatoxin B1 decreases methylationISOOR1D2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of OR1D2 geneCTDPMID:27153756
Or1d2Mousebisphenol A decreases expressionISOOr1d2 (Rattus norvegicus)6480464bisphenol A results in decreased expression of OR1D2 mRNACTDPMID:25181051
Or1d2Mousecadmium dichloride decreases expressionISOOR1D2 (Homo sapiens)6480464Cadmium Chloride results in decreased expression of OR1D2 mRNACTDPMID:21457566
Or1d2Mousecalcium atom multiple interactionsISOOR1D2 (Homo sapiens)6480464[bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of CalciumCTDPMID:21454470
Or1d2Mousecalcium(0) multiple interactionsISOOR1D2 (Homo sapiens)6480464[bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of CalciumCTDPMID:21454470
Or1d2Mousecrocidolite asbestos affects expressionISOOR1D2 (Homo sapiens)6480464Asbestos and Crocidolite affects the expression of OR1D2 mRNACTDPMID:17331233
Or1d2Mouseglycidol increases expressionISOOr1d2 (Rattus norvegicus)6480464glycidol results in increased expression of OR1D2 mRNACTDPMID:24395379
Or1d2Mouseresveratrol multiple interactionsISOOR1D2 (Homo sapiens)6480464[Plant Extracts co-treated with Resveratrol] results in decreased expression of OR1D2 mRNACTDPMID:23557933
Or1d2Mousethalidomide increases expressionEXP 6480464Thalidomide results in increased expression of OR1D2 mRNACTDPMID:26217789
Or1d2Mouseundecanal multiple interactionsISOOR1D2 (Homo sapiens)6480464undecanal inhibits the reaction [bourgeonal binds to and results in increased activity of OR1D2 protein]CTDPMID:21454470
Or1d2Mousevalproic acid decreases methylationISOOR1D2 (Homo sapiens)6480464Valproic Acid results in decreased methylation of OR1D2 geneCTDPMID:29154799
Or1d2Mousezinc atom decreases expressionISOOR1D2 (Homo sapiens)6480464Zinc results in decreased expression of OR1D2 mRNACTDPMID:19071009
Or1d2Mousezinc(0) decreases expressionISOOR1D2 (Homo sapiens)6480464Zinc results in decreased expression of OR1D2 mRNACTDPMID:19071009

1 to 14 of 14 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or1d2MouseG protein-coupled receptor signaling pathway involved_inISOOR1D2 (Homo sapiens)9068941 PMID:16820410UniProtPMID:16820410
Or1d2MouseG protein-coupled receptor signaling pathway acts_upstream_of_or_withinISAprotein_id:AAF033312290270 PMID:14611657MGIPMID:14611657
Or1d2Mousesensory perception of smell acts_upstream_of_or_withinISAprotein_id:AAF033312290270 PMID:14611657MGIPMID:14611657
Or1d2Mousesignal transduction involved_inIBAPANTHER:PTN001239850 and UniProtKB:P349822290270 GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or1d2Mousemembrane located_inISAprotein_id:AAF033312290270 PMID:14611657MGIPMID:14611657
Or1d2Mouseplasma membrane is_active_inIBAPANTHER:PTN001239850 and UniProtKB:A6NND42290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or1d2Mouseidentical protein binding enablesISOUniProtKB:P349822290270 GO_CentralGO_REF:0000119
Or1d2Mouseolfactory receptor activity enablesIBAPANTHER:PTN001239850 more ...2290270 GO_CentralGO_REF:0000033
Or1d2Mouseolfactory receptor activity enablesISAprotein_id:AAF033312290270 PMID:14611657MGIPMID:14611657
Or1d2Mouseolfactory receptor activity enablesISOUniProtKB:P349822290270 GO_CentralGO_REF:0000119


#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11170746   PMID:11802173   PMID:11875048   PMID:14611657   PMID:21267068   PMID:21873635   PMID:32295537  



Or1d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,255,497 - 74,256,435 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,252,895 - 74,257,044 (+)EnsemblGRCm39 Ensembl
GRCm381174,364,671 - 74,365,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,362,069 - 74,366,218 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,178,173 - 74,179,111 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,180,866 - 74,181,804 (+)NCBIMGSCv36mm8
Celera1181,877,216 - 81,878,154 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
OR1D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,088,484 - 3,104,422 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,088,484 - 3,104,422 (-)EnsemblGRCh38hg38GRCh38
GRCh37172,991,778 - 3,007,716 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,942,102 - 2,943,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 34172,942,101 - 2,943,040NCBI
Celera173,013,570 - 3,014,508 (-)NCBICelera
Cytogenetic Map17p13.3ENTREZGENE
HuRef172,887,600 - 2,888,538 (-)NCBIHuRef
CHM1_1173,004,202 - 3,005,140 (-)NCBICHM1_1
T2T-CHM13v2.0172,976,732 - 2,992,671 (-)NCBIT2T-CHM13v2.0
Or1d2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81059,711,377 - 59,712,312 (+)NCBIGRCr8
mRatBN7.21059,212,947 - 59,213,882 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,207,257 - 59,214,085 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1063,858,981 - 63,859,916 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,364,592 - 63,365,527 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01058,827,074 - 58,828,009 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,160,125 - 61,161,060 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,152,379 - 61,153,198 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,160,125 - 61,161,060 (+)EnsemblRnor6.0rn6Rnor6.0
RGSC_v3.41061,632,798 - 61,633,733 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11061,646,420 - 61,647,356 (+)NCBI
Celera1058,245,853 - 58,246,788 (+)NCBICelera
Cytogenetic Map10q24NCBI
LOC100992356
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21910,657,516 - 10,678,468 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11712,624,688 - 12,644,835 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,081,014 - 3,087,934 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,083,513 - 3,084,466 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,083,513 - 3,084,451 (-)Ensemblpanpan1.1panPan2
OR1D10P
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,061,492 - 47,062,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl947,061,492 - 47,062,498 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,213,588 - 46,214,594 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0947,896,453 - 47,897,459 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl947,896,453 - 47,897,459 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,660,812 - 46,661,818 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,957,061 - 46,958,067 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,009,991 - 47,010,997 (-)NCBIUU_Cfam_GSD_1.0
LOC103242147
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,754,981 - 2,766,197 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl162,765,210 - 2,766,148 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605919,135,063 - 19,136,087 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:85
Interacting mature miRNAs:89
Transcripts:ENSMUST00000077794
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse

1 to 10 of 51 rows






Ensembl Acc Id: ENSMUST00000077794   ⟹   ENSMUSP00000076967
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,255,497 - 74,256,435 (+)Ensembl
GRCm38.p6 Ensembl1174,364,671 - 74,365,609 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216362   ⟹   ENSMUSP00000149922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,252,895 - 74,257,044 (+)Ensembl
GRCm38.p6 Ensembl1174,362,069 - 74,366,218 (+)Ensembl
RefSeq Acc Id: NM_001011851   ⟹   NP_001011851
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,255,497 - 74,256,435 (+)NCBI
GRCm381174,364,671 - 74,365,609 (+)ENTREZGENE
MGSCv371174,178,173 - 74,179,111 (+)RGD
Celera1181,877,216 - 81,878,154 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein RefSeqs NP_001011851 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG42793 (Get FASTA)   NCBI Sequence Viewer  
  AAP70934 (Get FASTA)   NCBI Sequence Viewer  
  EDL12770 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000076967
  ENSMUSP00000076967.2
  ENSMUSP00000149922.2
RefSeq Acc Id: NP_001011851   ⟸   NM_001011851
- UniProtKB: Q7TRW7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000149922   ⟸   ENSMUST00000216362
Ensembl Acc Id: ENSMUSP00000076967   ⟸   ENSMUST00000077794
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-Q7TRW7-F1-model_v2 AlphaFold Q7TRW7 1-312 view protein structure



1 to 20 of 20 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000058275 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000077794 ENTREZGENE
  ENSMUST00000077794.4 UniProtKB/TrEMBL
  ENSMUST00000216362.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258153 UniProtKB/TrEMBL
MGD MGI:3030246 ENTREZGENE
NCBI Gene 258153 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1d2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRW7 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or1d2  olfactory receptor family 1 subfamily D member 2  Olfr412  olfactory receptor 412  Symbol and/or name change 5135510 APPROVED