Eif2b3 (eukaryotic translation initiation factor 2B, subunit 3) - Rat Genome Database

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Gene: Eif2b3 (eukaryotic translation initiation factor 2B, subunit 3) Mus musculus
Analyze
Symbol: Eif2b3
Name: eukaryotic translation initiation factor 2B, subunit 3
RGD ID: 1552242
MGI Page MGI
Description: Predicted to enable guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to contribute to translation factor activity, RNA binding. Predicted to be involved in several processes, including T cell receptor signaling pathway; cytoplasmic translational initiation; and oligodendrocyte development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2B complex and guanyl-nucleotide exchange factor complex. Is expressed in central nervous system; gonad; retina; and thyroid gland. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 3. Orthologous to human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1190002P15Rik; eukaryotic translation initiation factor 2B, subunit 3 gamma; translation initiation factor eIF-2B subunit gamma; translation initiation factor eIF2B subunit gamma
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,876,559 - 116,944,049 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,876,599 - 116,944,503 (+)EnsemblGRCm39 Ensembl
GRCm384117,019,399 - 117,086,852 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,019,402 - 117,087,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,692,013 - 116,759,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,517,334 - 116,585,238 (+)NCBIMGSCv36mm8
Celera4115,754,605 - 115,822,241 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The mechanism of eukaryotic translation initiation: new insights and challenges. Hinnebusch AG and Lorsch JR, Cold Spring Harb Perspect Biol. 2012 Oct 1;4(10). pii: a011544. doi: 10.1101/cshperspect.a011544.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11752298   PMID:12226475   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:24194600   PMID:27626380  


Genomics

Comparative Map Data
Eif2b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,876,559 - 116,944,049 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,876,599 - 116,944,503 (+)EnsemblGRCm39 Ensembl
GRCm384117,019,399 - 117,086,852 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,019,402 - 117,087,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,692,013 - 116,759,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,517,334 - 116,585,238 (+)NCBIMGSCv36mm8
Celera4115,754,605 - 115,822,241 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
EIF2B3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38144,850,522 - 44,986,595 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl144,850,522 - 44,986,722 (-)EnsemblGRCh38hg38GRCh38
GRCh37145,316,194 - 45,452,267 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,089,037 - 45,224,869 (-)NCBINCBI36Build 36hg18NCBI36
Build 34144,985,606 - 45,121,349NCBI
Celera143,598,935 - 43,735,148 (-)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef143,428,607 - 43,564,682 (-)NCBIHuRef
CHM1_1145,432,292 - 45,568,970 (-)NCBICHM1_1
T2T-CHM13v2.0144,721,756 - 44,858,197 (-)NCBIT2T-CHM13v2.0
Eif2b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,728,764 - 135,795,276 (+)NCBIGRCr8
mRatBN7.25130,492,167 - 130,558,692 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,492,220 - 130,563,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5133,123,091 - 133,188,111 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,877,699 - 134,942,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,900,110 - 134,965,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,882,946 - 135,949,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,882,967 - 135,949,818 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,677,822 - 139,744,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,323,754 - 137,398,327 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15137,328,979 - 137,403,552 (+)NCBI
Celera5129,018,586 - 129,084,980 (+)NCBICelera
Cytogenetic Map5q36NCBI
Eif2b3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546413,254,228 - 13,378,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546413,254,228 - 13,378,832 (+)NCBIChiLan1.0ChiLan1.0
EIF2B3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21181,821,005 - 181,956,859 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11180,962,564 - 181,098,380 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,154,600 - 44,290,407 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1145,520,587 - 45,655,424 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl145,525,137 - 45,650,259 (-)Ensemblpanpan1.1panPan2
EIF2B3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11515,337,421 - 15,481,427 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1515,337,483 - 15,481,425 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1515,458,142 - 15,601,622 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01515,492,735 - 15,636,800 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1515,492,756 - 15,636,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11515,289,691 - 15,433,641 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01515,357,619 - 15,501,550 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01515,429,796 - 15,574,243 (+)NCBIUU_Cfam_GSD_1.0
Eif2b3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505860,250,716 - 60,362,626 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,075,204 - 26,187,459 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,075,503 - 26,187,459 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2B3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6166,353,934 - 166,494,698 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16166,353,918 - 166,487,581 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26153,765,212 - 153,900,676 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2B3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12087,800,695 - 87,945,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2087,800,670 - 87,945,569 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603328,995,636 - 29,143,641 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif2b3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624906733,146 - 892,362 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624906733,148 - 882,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif2b3
1833 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2062
Count of miRNA genes:797
Interacting mature miRNAs:1055
Transcripts:ENSMUST00000070610, ENSMUST00000106447, ENSMUST00000106448, ENSMUST00000129587, ENSMUST00000135121, ENSMUST00000151760, ENSMUST00000155181
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488118237118557197Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4110857197125893793Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301996Mmtg2_mmodifier of mammary tumor growth 2 (mouse)Not determined4116270979124055180Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006502649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK004460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE952243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM945817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ828648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY277686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV041891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000070610   ⟹   ENSMUSP00000070334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,879,352 - 116,944,042 (+)Ensembl
GRCm38.p6 Ensembl4117,022,155 - 117,086,845 (+)Ensembl
RefSeq Acc Id: ENSMUST00000106447   ⟹   ENSMUSP00000102055
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,876,605 - 116,930,457 (+)Ensembl
GRCm38.p6 Ensembl4117,019,408 - 117,073,260 (+)Ensembl
RefSeq Acc Id: ENSMUST00000106448   ⟹   ENSMUSP00000102056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,876,599 - 116,944,049 (+)Ensembl
GRCm38.p6 Ensembl4117,019,402 - 117,086,852 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129587
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,938,478 - 116,944,045 (+)Ensembl
GRCm38.p6 Ensembl4117,081,281 - 117,086,848 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,901,673 - 116,916,522 (+)Ensembl
GRCm38.p6 Ensembl4117,044,476 - 117,059,325 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151760
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,923,668 - 116,931,497 (+)Ensembl
GRCm38.p6 Ensembl4117,066,471 - 117,074,300 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155181
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,924,660 - 116,944,503 (+)Ensembl
GRCm38.p6 Ensembl4117,067,463 - 117,087,306 (+)Ensembl
RefSeq Acc Id: NM_001111277   ⟹   NP_001104747
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,876,599 - 116,944,049 (+)NCBI
GRCm384117,019,402 - 117,086,852 (+)NCBI
MGSCv374116,692,013 - 116,759,457 (+)RGD
Celera4115,754,605 - 115,822,241 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001355225   ⟹   NP_001342154
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,876,599 - 116,944,049 (+)NCBI
GRCm384117,019,402 - 117,086,852 (+)NCBI
Sequence:
RefSeq Acc Id: NM_175135   ⟹   NP_780344
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,876,599 - 116,930,457 (+)NCBI
GRCm384117,019,402 - 117,073,260 (+)NCBI
MGSCv374116,692,013 - 116,759,457 (+)RGD
Celera4115,754,605 - 115,822,241 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006502649   ⟹   XP_006502712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394116,876,559 - 116,930,571 (+)NCBI
GRCm384117,019,399 - 117,074,879 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_780344   ⟸   NM_175135
- Peptide Label: isoform 2
- UniProtKB: Q3UKV0 (UniProtKB/TrEMBL),   B1AUN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104747   ⟸   NM_001111277
- Peptide Label: isoform 1
- UniProtKB: B1AUN2 (UniProtKB/TrEMBL),   B1AUN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502712   ⟸   XM_006502649
- Peptide Label: isoform X1
- UniProtKB: B1AUN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001342154   ⟸   NM_001355225
- Peptide Label: isoform 3
RefSeq Acc Id: ENSMUSP00000070334   ⟸   ENSMUST00000070610
RefSeq Acc Id: ENSMUSP00000102055   ⟸   ENSMUST00000106447
RefSeq Acc Id: ENSMUSP00000102056   ⟸   ENSMUST00000106448
Protein Domains
Nucleotidyl transferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1AUN2-F1-model_v2 AlphaFold B1AUN2 1-452 view protein structure

Promoters
RGD ID:6835185
Promoter ID:MM_KWN:39208
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000094862,   NM_175135,   OTTMUST00000022643,   UC008UHV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,691,896 - 116,692,412 (+)MPROMDB
RGD ID:6835187
Promoter ID:MM_KWN:39210
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:UC008UHW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,713,921 - 116,714,421 (+)MPROMDB
RGD ID:6884346
Promoter ID:EPDNEW_M5624
Type:initiation region
Name:Eif2b3_1
Description:Mus musculus eukaryotic translation initiation factor 2B, subunit3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384117,019,426 - 117,019,486EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1313286 AgrOrtholog
Ensembl Genes ENSMUSG00000028683 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070610.6 UniProtKB/TrEMBL
  ENSMUST00000106447 ENTREZGENE
  ENSMUST00000106447.9 UniProtKB/TrEMBL
  ENSMUST00000106448 ENTREZGENE
  ENSMUST00000106448.9 UniProtKB/TrEMBL
Gene3D-CATH Hexapeptide repeat proteins UniProtKB/TrEMBL
InterPro NTP_transferase UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  Trimer_LpxA-like UniProtKB/TrEMBL
KEGG Report mmu:108067 UniProtKB/TrEMBL
MGD MGI:1313286 ENTREZGENE
NCBI Gene 108067 ENTREZGENE
PANTHER TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA UniProtKB/TrEMBL
  TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA UniProtKB/TrEMBL
Pfam NTP_transferase UniProtKB/TrEMBL
PhenoGen Eif2b3 PhenoGen
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
  Trimer_LpxA_like UniProtKB/TrEMBL
UniProt A0AUM9_MOUSE UniProtKB/TrEMBL
  A4FUS0_MOUSE UniProtKB/TrEMBL
  B1AUN2 ENTREZGENE, UniProtKB/TrEMBL
  B1AUN3 ENTREZGENE, UniProtKB/TrEMBL
  Q3T9T4_MOUSE UniProtKB/TrEMBL
  Q3UKV0 ENTREZGENE, UniProtKB/TrEMBL