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Gene: EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma) Homo sapiens
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Symbol: EIF2B3
Name: eukaryotic translation initiation factor 2B subunit gamma
Description: Contributes to guanyl-nucleotide exchange factor activity and translation initiation factor activity. Involved in T cell receptor signaling pathway; oligodendrocyte development; and translational initiation. Localizes to the eukaryotic translation initiation factor 2B complex. Implicated in leukoencephalopathy with vanishing white matter.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EIF-2B; eIF-2B GDP-GTP exchange factor subunit gamma; EIF2Bgamma; eukaryotic translation initiation factor 2b, subunit 3 (gamma, 58kd); eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl144,850,522 - 44,986,722 (-)Ensembl
GRCh38144,850,522 - 44,986,722 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37145,316,194 - 45,452,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,089,037 - 45,224,869 (-)NCBINCBI36hg18NCBI36
Build 34144,985,606 - 45,121,349NCBI
Celera143,598,935 - 43,735,148 (-)NCBI
Cytogenetic Map1p34.1NCBI
HuRef143,428,607 - 43,564,682 (-)NCBIHuRef
CHM1_1145,432,292 - 45,568,970 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on EIF2B3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732190
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.