Tbc1d22a (TBC1 domain family, member 22a) - Rat Genome Database

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Gene: Tbc1d22a (TBC1 domain family, member 22a) Mus musculus
Analyze
Symbol: Tbc1d22a
Name: TBC1 domain family, member 22a
RGD ID: 1551453
MGI Page MGI
Description: Predicted to enable 14-3-3 protein binding activity; GTPase activator activity; and protein homodimerization activity. Predicted to be active in Golgi apparatus. Orthologous to human TBC1D22A (TBC1 domain family member 22A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC023106; D15Ertd781; D15Ertd781e; DNA segment, Chr 15, ERATO Doi 781, expressed; MGC28337; TBC1 domain family member 22A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391586,095,502 - 86,382,704 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1586,098,660 - 86,382,704 (+)EnsemblGRCm39 Ensembl
GRCm381586,214,411 - 86,498,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1586,214,459 - 86,498,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371586,044,889 - 86,328,933 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361586,042,225 - 86,326,269 (+)NCBIMGSCv36mm8
Celera1588,356,819 - 88,637,955 (+)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tbc1d22aMouseintellectual disability  ISORGD:16020078554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Tbc1d22aMousePhelan-McDermid syndrome  ISORGD:16020078554872ClinVar Annotator: match by term: Phelan-McDermid syndromeClinVar 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tbc1d22aMouse1,2-dimethylhydrazine decreases expressionEXP 64804641,2-Dimethylhydrazine results in decreased expression of TBC1D22A mRNACTDPMID:22206623
Tbc1d22aMouse2,2',4,4'-Tetrabromodiphenyl ether increases expressionISORGD:160200764804642,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of TBC1D22A mRNACTDPMID:19095052
Tbc1d22aMouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of TBC1D22A mRNACTDPMID:21570461
Tbc1d22aMouse2,3,7,8-Tetrachlorodibenzofuran decreases expressionISORGD:130658864804642,3,7,8-tetrachlorodibenzofuran results in decreased expression of TBC1D22A mRNACTDPMID:32109520
Tbc1d22aMouse3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of TBC1D22A mRNACTDPMID:20188158
Tbc1d22aMouseaflatoxin B1 affects expressionISORGD:16020076480464Aflatoxin B1 affects the expression of TBC1D22A proteinCTDPMID:20106945
Tbc1d22aMouseaflatoxin B1 decreases methylationISORGD:16020076480464Aflatoxin B1 results in decreased methylation of TBC1D22A polyA tailCTDPMID:30157460
Tbc1d22aMouseaflatoxin B1 increases methylationISORGD:16020076480464Aflatoxin B1 results in increased methylation of TBC1D22A intronCTDPMID:30157460
Tbc1d22aMouseaflatoxin B1 decreases expressionISORGD:16020076480464Aflatoxin B1 results in decreased expression of TBC1D22A mRNACTDPMID:21641981|PMID:22100608
Tbc1d22aMouseAflatoxin B2 alpha affects methylationISORGD:16020076480464aflatoxin B2 affects the methylation of TBC1D22A intronCTDPMID:30157460
Tbc1d22aMouseantirheumatic drug decreases expressionISORGD:16020076480464Antirheumatic Agents results in decreased expression of TBC1D22A mRNACTDPMID:24449571
Tbc1d22aMousearistolochic acid A decreases expressionISORGD:16020076480464aristolochic acid I results in decreased expression of TBC1D22A mRNACTDPMID:33212167
Tbc1d22aMousearsane affects methylationISORGD:16020076480464Arsenic affects the methylation of TBC1D22A geneCTDPMID:25304211
Tbc1d22aMousearsenic atom affects methylationISORGD:16020076480464Arsenic affects the methylation of TBC1D22A geneCTDPMID:25304211
Tbc1d22aMouseatrazine affects methylationISORGD:13065886480464Atrazine affects the methylation of TBC1D22A geneCTDPMID:28931070|PMID:35440735
Tbc1d22aMousebenzo[a]pyrene decreases expressionEXP 6480464Benzo(a)pyrene results in decreased expression of TBC1D22A mRNACTDPMID:19770486
Tbc1d22aMousebenzo[a]pyrene affects methylationISORGD:16020076480464Benzo(a)pyrene affects the methylation of TBC1D22A intronCTDPMID:30157460
Tbc1d22aMousebenzo[a]pyrene decreases expressionISORGD:16020076480464Benzo(a)pyrene results in decreased expression of TBC1D22A mRNACTDPMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291|PMID:32234424
Tbc1d22aMousebenzo[a]pyrene diol epoxide I decreases expressionISORGD:160200764804647,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TBC1D22A mRNACTDPMID:26238291
Tbc1d22aMousebenzo[e]pyrene affects methylationISORGD:16020076480464benzo(e)pyrene affects the methylation of TBC1D22A intronCTDPMID:30157460

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tbc1d22aMouseregulation of cilium assembly NOT|involved_inISORGD:16020079068941 PMID:17646400UniProtPMID:17646400

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tbc1d22aMouseGolgi apparatus is_active_inIBAPANTHER:PTN000538121|WB:WBGene00009322|CGD:CAL0000181837|SGD:S0000055962290270 GO_CentralGO_REF:0000033

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tbc1d22aMouse14-3-3 protein binding enablesISOUniProtKB:Q8WUA72290270 GO_CentralGO_REF:0000119
Tbc1d22aMouse14-3-3 protein binding enablesISSUniProtKB:Q8WUA72290270 UniProtGO_REF:0000024
Tbc1d22aMouseGTPase activator activity enablesIEAUniProtKB-KW:KW-03432290270 UniProtGO_REF:0000043
Tbc1d22aMouseGTPase activator activity enablesIBAPANTHER:PTN000537561|SGD:S000003332|FB:FBgn0262740|UniProtKB:Q96CN4|SGD:S000006170|UniProtKB:Q92738|MGI:1913937|MGI:2144695|WB:WBGene00007167|UniProtKB:Q9Y2I9|UniProtKB:O43147|SGD:S000005596|UniProtKB:Q8IYX1|SGD:S000005472|UniProtKB:Q9BYX2|UniProtKB:Q4KMP7|UniProtKB:Q96HU1|UniProtKB:O60447|UniProtKB:Q2NKQ1|SGD:S000005237|UniProtKB:Q3MII6|UniProtKB:Q8TBP0|WB:WBGene00022880|MGI:2385326|SGD:S000002393|dictyBase:DDB_G0280955|FB:FBgn0038855|dictyBase:DDB_G02761192290270 GO_CentralGO_REF:0000033
Tbc1d22aMouseprotein binding enablesISOUniProtKB:P27348|UniProtKB:P31946|UniProtKB:P61981|UniProtKB:P62258|UniProtKB:P63104|UniProtKB:Q04917|UniProtKB:Q9H3P7|UniProtKB:Q9Y6D69068941 PMID:23572552UniProtPMID:23572552
Tbc1d22aMouseprotein binding enablesISOUniProtKB:O43933|UniProtKB:O76024|UniProtKB:P02766|UniProtKB:P498219068941 PMID:32814053IntActPMID:32814053
Tbc1d22aMouseprotein binding enablesISOUniProtKB:Q9H3P79068941 PMID:23572552, PMID:33961781IntActPMID:23572552|PMID:33961781
Tbc1d22aMouseprotein homodimerization activity enablesISSUniProtKB:Q8WUA72290270 UniProtGO_REF:0000024
Tbc1d22aMouseprotein homodimerization activity enablesISOUniProtKB:Q8WUA72290270 GO_CentralGO_REF:0000119
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#
Reference Title
Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27103069   PMID:27626380   PMID:30550785   PMID:30973865   PMID:32245826   PMID:32325033   PMID:32554809   PMID:38355793  



Tbc1d22a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391586,095,502 - 86,382,704 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1586,098,660 - 86,382,704 (+)EnsemblGRCm39 Ensembl
GRCm381586,214,411 - 86,498,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1586,214,459 - 86,498,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371586,044,889 - 86,328,933 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361586,042,225 - 86,326,269 (+)NCBIMGSCv36mm8
Celera1588,356,819 - 88,637,955 (+)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.56NCBI
TBC1D22A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382246,762,650 - 47,175,699 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2246,762,617 - 47,175,699 (+)EnsemblGRCh38hg38GRCh38
GRCh372247,158,547 - 47,571,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362245,537,213 - 45,948,390 (+)NCBINCBI36Build 36hg18NCBI36
Celera2231,074,220 - 31,486,114 (+)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2230,103,503 - 30,516,056 (+)NCBIHuRef
CHM1_12247,117,886 - 47,530,004 (+)NCBICHM1_1
T2T-CHM13v2.02247,250,621 - 47,665,617 (+)NCBIT2T-CHM13v2.0
Tbc1d22a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87119,172,284 - 119,457,271 (+)NCBIGRCr8
mRatBN7.27117,292,481 - 117,577,473 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7117,292,631 - 117,577,483 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7119,044,006 - 119,331,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07121,269,640 - 121,557,332 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07121,239,221 - 121,526,927 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07127,081,769 - 127,227,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7127,081,978 - 127,223,231 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07126,792,288 - 126,930,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.17124,240,095 - 124,527,412 (+)NCBI
Celera7113,582,538 - 114,076,520 (+)NCBICelera
Cytogenetic Map7q34NCBI
Tbc1d22a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541330,709,724 - 31,026,238 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541330,710,432 - 31,025,784 (+)NCBIChiLan1.0ChiLan1.0
TBC1D22A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22356,605,984 - 57,025,743 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12259,297,405 - 59,716,769 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02226,934,409 - 27,353,029 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12245,830,747 - 46,241,738 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2245,830,747 - 46,241,738 (+)Ensemblpanpan1.1panPan2
TBC1D22A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11019,196,866 - 19,532,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1019,070,467 - 19,532,062 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1019,119,926 - 19,454,053 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01019,933,410 - 20,267,704 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1019,933,339 - 20,267,651 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11019,651,625 - 19,985,731 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01019,964,022 - 20,298,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01020,145,684 - 20,479,843 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d22a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049452,963,792 - 3,272,058 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366292,966,507 - 3,272,030 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366292,965,289 - 3,272,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D22A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,528,921 - 2,787,304 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.152,528,920 - 2,787,313 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25126,533 - 312,712 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D22A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11929,260,995 - 29,681,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1929,261,018 - 29,684,409 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604595,780,108 - 96,253,332 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d22a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247522,903,130 - 3,273,535 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247522,816,547 - 3,272,693 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Tbc1d22a
9048 total Variants

Predicted Target Of
Summary Value
Count of predictions:788
Count of miRNA genes:453
Interacting mature miRNAs:544
Transcripts:ENSMUST00000063414
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 44 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse

1 to 10 of 44 rows
D18941  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15E2UniSTS
cM Map1549.3UniSTS
Whitehead_YAC15 UniSTS
UniSTS:237373  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381586,213,864 - 86,213,957UniSTSGRCm38
MGSCv371586,044,294 - 86,044,387UniSTSGRCm37
Celera1588,360,044 - 88,360,137UniSTS
Celera1588,356,224 - 88,356,317UniSTS
Cytogenetic Map15E2UniSTS
cM Map1549.3UniSTS
D15Ertd320e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381586,354,318 - 86,354,521UniSTSGRCm38
MGSCv371586,184,748 - 86,184,951UniSTSGRCm37
Celera1588,491,806 - 88,492,009UniSTS
Cytogenetic Map15E2UniSTS
cM Map1549.3UniSTS
D15Ertd781e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381586,498,198 - 86,498,398UniSTSGRCm38
MGSCv371586,328,628 - 86,328,828UniSTSGRCm37
Celera1588,637,650 - 88,637,850UniSTS
Cytogenetic Map15E2UniSTS
cM Map1549.3UniSTS






1 to 30 of 43 rows
RefSeq Transcripts NM_001358062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC116764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC146911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02064807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 43 rows

Ensembl Acc Id: ENSMUST00000063414   ⟹   ENSMUSP00000065721
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1586,098,660 - 86,382,704 (+)Ensembl
GRCm38.p6 Ensembl1586,214,459 - 86,498,503 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229242   ⟹   ENSMUSP00000155727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1586,119,706 - 86,176,363 (+)Ensembl
GRCm38.p6 Ensembl1586,235,505 - 86,292,162 (+)Ensembl
RefSeq Acc Id: NM_001358062   ⟹   NP_001344991
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,161,871 - 86,382,704 (+)NCBI
GRCm381586,277,675 - 86,498,503 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001409162   ⟹   NP_001396091
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_001409163   ⟹   NP_001396092
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_001409164   ⟹   NP_001396093
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_001409165   ⟹   NP_001396094
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_001409166   ⟹   NP_001396095
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_001409167   ⟹   NP_001396096
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
RefSeq Acc Id: NM_145476   ⟹   NP_663451
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,098,647 - 86,382,704 (+)NCBI
GRCm381586,214,459 - 86,498,503 (+)NCBI
MGSCv371586,044,889 - 86,328,933 (+)RGD
Celera1588,356,819 - 88,637,955 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036159365   ⟹   XP_036015258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,095,502 - 86,382,704 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159366   ⟹   XP_036015259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,095,502 - 86,382,704 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159367   ⟹   XP_036015260
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,161,866 - 86,382,704 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004938824
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,095,502 - 86,382,704 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004938825
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391586,095,502 - 86,382,704 (+)NCBI
Sequence:
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_663451   ⟸   NM_145476
- Peptide Label: isoform 1
- UniProtKB: Q8R5A6 (UniProtKB/Swiss-Prot),   Q8CA49 (UniProtKB/Swiss-Prot),   Q3U268 (UniProtKB/Swiss-Prot),   Q3U3T0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001344991   ⟸   NM_001358062
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000065721   ⟸   ENSMUST00000063414
Ensembl Acc Id: ENSMUSP00000155727   ⟸   ENSMUST00000229242
RefSeq Acc Id: XP_036015258   ⟸   XM_036159365
- Peptide Label: isoform X1
Rab-GAP TBC

Name Modeler Protein Id AA Range Protein Structure
AF-Q8R5A6-F1-model_v2 AlphaFold Q8R5A6 1-516 view protein structure

RGD ID:6825598
Promoter ID:MM_KWN:19348
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK012625_2810001A02RIK,   ENSMUST00000063414,   ENSMUST00000109385
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361586,044,529 - 86,045,029 (-)MPROMDB
RGD ID:8684770
Promoter ID:EPDNEW_M20364
Type:initiation region
Name:Tbc1d22a_1
Description:Mus musculus TBC1 domain family, member 22a , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381586,214,446 - 86,214,506EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000051864 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000063414 ENTREZGENE
  ENSMUST00000063414.9 UniProtKB/Swiss-Prot
Gene3D-CATH putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/Swiss-Prot
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/Swiss-Prot
InterPro Rab-GTPase-TBC_dom UniProtKB/Swiss-Prot
  Rab-GTPase_TBC_sf UniProtKB/Swiss-Prot
KEGG Report mmu:223754 UniProtKB/Swiss-Prot
MGD MGI:1289265 ENTREZGENE
NCBI Gene Tbc1d22a ENTREZGENE
PANTHER TBC1 DOMAIN FAMILY MEMBER 22A UniProtKB/Swiss-Prot
  TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot
Pfam RabGAP-TBC UniProtKB/Swiss-Prot
PhenoGen Tbc1d22a PhenoGen
PROSITE TBC_RABGAP UniProtKB/Swiss-Prot
SMART TBC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47923 UniProtKB/Swiss-Prot
UniProt A0A2R8W718_MOUSE UniProtKB/TrEMBL
  Q3U268 ENTREZGENE
  Q3U3T0 ENTREZGENE
  Q8CA49 ENTREZGENE
  Q8R5A6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3U268 UniProtKB/Swiss-Prot
  Q3U3T0 UniProtKB/Swiss-Prot
  Q8CA49 UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Tbc1d22a  TBC1 domain family, member 22a  D15Ertd781e  DNA segment, Chr 15, ERATO Doi 781, expressed  Symbol and/or name change 5135510 APPROVED
2024-08-21 D15Ertd781e  DNA segment, Chr 15, ERATO Doi 781, expressed  Tbc1d22a  TBC1 domain family, member 22a  Symbol and/or name change 5135510 APPROVED