Pde8a (phosphodiesterase 8A) - Rat Genome Database

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Gene: Pde8a (phosphodiesterase 8A) Mus musculus
Analyze
Symbol: Pde8a
Name: phosphodiesterase 8A
RGD ID: 1550182
MGI Page MGI
Description: Enables 3',5'-cyclic-AMP phosphodiesterase activity. Involved in cellular response to epidermal growth factor stimulus and positive regulation of ERK1 and ERK2 cascade. Is expressed in several structures, including genitourinary system; gut gland; integumental system; nervous system; and skeleton. Orthologous to human PDE8A (phosphodiesterase 8A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI551852; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A; mmPDE8; Pde; Pde8
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39780,863,013 - 80,984,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl780,863,344 - 80,984,281 (+)EnsemblGRCm39 Ensembl
GRCm38781,213,265 - 81,334,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,213,596 - 81,334,533 (+)EnsemblGRCm38mm10GRCm38
MGSCv37788,358,690 - 88,478,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36781,087,251 - 81,208,043 (+)NCBIMGSCv36mm8
Celera778,686,223 - 78,738,796 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMouseBloom syndrome  ISOPDE8A (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Pde8aMousecolorectal cancer  ISOPDE8A (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMouse1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of PDE8A mRNACTDPMID:22206623
Pde8aMouse17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of PDE8A mRNACTDPMID:17942748
Pde8aMouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PDE8A mRNACTDPMID:19933214
Pde8aMouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPde8a (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of PDE8A mRNACTDPMID:21215274 more ...
Pde8aMouse3',5'-cyclic AMP multiple interactionsISOPDE8A (Homo sapiens)6480464Dipyridamole inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP] and E 4021 inhibits the reaction [PDE8A protein results in increased metabolism of Cyclic AMP]CTDPMID:12681444
Pde8aMouse3',5'-cyclic AMP increases metabolic processingISOPDE8A (Homo sapiens)6480464PDE8A protein results in increased metabolism of Cyclic AMPCTDPMID:12681444
Pde8aMouse3',5'-cyclic AMP increases hydrolysisEXP 6480464PDE8A protein results in increased hydrolysis of Cyclic AMPCTDPMID:9671792
Pde8aMouse3',5'-cyclic AMP multiple interactionsEXP 6480464Dipyridamole inhibits the reaction [PDE8A protein results in increased hydrolysis of Cyclic AMP]CTDPMID:9671792
Pde8aMouse6-propyl-2-thiouracil decreases expressionISOPde8a (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of PDE8A mRNACTDPMID:24780913
Pde8aMouseacrolein multiple interactionsISOPDE8A (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PDE8A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PDE8A mRNACTDPMID:32699268
Pde8aMouseall-trans-retinoic acid increases expressionISOPDE8A (Homo sapiens)6480464Tretinoin results in increased expression of PDE8A mRNACTDPMID:21934132
Pde8aMousealpha-pinene multiple interactionsISOPDE8A (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PDE8A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PDE8A mRNACTDPMID:32699268
Pde8aMouseantirheumatic drug increases expressionISOPDE8A (Homo sapiens)6480464Antirheumatic Agents results in increased expression of PDE8A mRNACTDPMID:24449571
Pde8aMousearistolochic acid A decreases expressionISOPDE8A (Homo sapiens)6480464aristolochic acid I results in decreased expression of PDE8A mRNACTDPMID:33212167
Pde8aMousearsane affects methylationISOPDE8A (Homo sapiens)6480464Arsenic affects the methylation of PDE8A geneCTDPMID:25304211
Pde8aMousearsane multiple interactionsISOPDE8A (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PDE8A mRNACTDPMID:39836092
Pde8aMousearsenic atom affects methylationISOPDE8A (Homo sapiens)6480464Arsenic affects the methylation of PDE8A geneCTDPMID:25304211
Pde8aMousearsenic atom multiple interactionsISOPDE8A (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PDE8A mRNACTDPMID:39836092
Pde8aMousearsenite(3-) increases expressionEXP 6480464arsenite results in increased expression of PDE8A mRNACTDPMID:33053406
Pde8aMousearsenous acid increases expressionISOPDE8A (Homo sapiens)6480464Arsenic Trioxide results in increased expression of PDE8A mRNACTDPMID:22521957

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Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMousecAMP catabolic process involved_inIEAUniPathway:UPA007622290270 UniProtGO_REF:0000041
Pde8aMousecAMP-mediated signaling involved_inIBAPANTHER:PTN001682918 and CGD:CAL00001782662290270 GO_CentralGO_REF:0000033
Pde8aMousecellular response to epidermal growth factor stimulus involved_inIBAPANTHER:PTN002602939 more ...2290270 GO_CentralGO_REF:0000033
Pde8aMousecellular response to epidermal growth factor stimulus involved_inISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMousecellular response to epidermal growth factor stimulus involved_inIMP 2290270 PMID:23509299UniProtPMID:23509299
Pde8aMousepositive regulation of ERK1 and ERK2 cascade involved_inIBAPANTHER:PTN000886896 more ...2290270 GO_CentralGO_REF:0000033
Pde8aMousepositive regulation of ERK1 and ERK2 cascade involved_inIMP 2290270 PMID:23509299UniProtPMID:23509299
Pde8aMousepositive regulation of ERK1 and ERK2 cascade involved_inISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMousesignal transduction involved_inIEAInterPro:IPR002073 and InterPro:IPR0369712290270 InterProGO_REF:0000002
1 to 9 of 9 rows

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMouse3',5'-cyclic-AMP phosphodiesterase activity enablesIBAPANTHER:PTN001682918 more ...2290270 GO_CentralGO_REF:0000033
Pde8aMouse3',5'-cyclic-AMP phosphodiesterase activity enablesIDA 2290270 PMID:9671792MGIPMID:9671792
Pde8aMouse3',5'-cyclic-AMP phosphodiesterase activity enablesISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMouse3',5'-cyclic-GMP phosphodiesterase activity enablesISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMouse3',5'-cyclic-GMP phosphodiesterase activity enablesIEAUniProtKB:O60658 and ensembl:ENSP000003780562290270 EnsemblGO_REF:0000107
Pde8aMouse3',5'-cyclic-GMP phosphodiesterase activity enablesIBAPANTHER:PTN001682918 more ...2290270 GO_CentralGO_REF:0000033
Pde8aMousekinase binding enablesISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMousekinase binding enablesIEAUniProtKB:O60658 and ensembl:ENSP000003780562290270 EnsemblGO_REF:0000107
Pde8aMousemetal ion binding enablesIEAUniProtKB-KW:KW-04792290270 UniProtGO_REF:0000043
Pde8aMouseprotein kinase activator activity enablesISOUniProtKB:O606582290270 GO_CentralGO_REF:0000119
Pde8aMouseprotein kinase activator activity enablesIEAUniProtKB:O60658 and ensembl:ENSP000003780562290270 EnsemblGO_REF:0000107
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMouseprotein kinase A (PKA) signaling pathway   ISOPDE8A (Homo sapiens)2312479 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pde8aMousepurine metabolic pathway  IEA 6907045 KEGGmmu:00230

#
Reference Title
Reference Citation
1. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Conti M and Beavo J, Annu Rev Biochem. 2007;76:481-511.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. Soderling SH, etal., Proc Natl Acad Sci U S A 1998 Jul 21;95(15):8991-6.
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11371644   PMID:12477932   PMID:14610273   PMID:14681479   PMID:16141072   PMID:16141073   PMID:16696947  
PMID:16829211   PMID:17110338   PMID:17172443   PMID:17307970   PMID:17967808   PMID:18287559   PMID:20353794   PMID:20711499   PMID:21187369   PMID:21267068   PMID:21873635   PMID:22232524  
PMID:23509299   PMID:24194600   PMID:25852085   PMID:27626380   PMID:28851628   PMID:32325033   PMID:38355793   PMID:38506047   PMID:38782837  



Pde8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39780,863,013 - 80,984,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl780,863,344 - 80,984,281 (+)EnsemblGRCm39 Ensembl
GRCm38781,213,265 - 81,334,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,213,596 - 81,334,533 (+)EnsemblGRCm38mm10GRCm38
MGSCv37788,358,690 - 88,478,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36781,087,251 - 81,208,043 (+)NCBIMGSCv36mm8
Celera778,686,223 - 78,738,796 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.71NCBI
PDE8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381584,980,467 - 85,139,142 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1584,980,440 - 85,139,145 (+)EnsemblGRCh38hg38GRCh38
GRCh371585,523,698 - 85,682,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361583,326,209 - 83,483,377 (+)NCBINCBI36Build 36hg18NCBI36
Celera1561,951,944 - 62,111,125 (+)NCBICelera
Cytogenetic Map15q25.3NCBI
HuRef1561,609,653 - 61,768,261 (+)NCBIHuRef
CHM1_11585,364,949 - 85,523,920 (+)NCBICHM1_1
T2T-CHM13v2.01582,732,711 - 82,891,368 (+)NCBIT2T-CHM13v2.0
Pde8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,575,203 - 144,698,216 (+)NCBIGRCr8
mRatBN7.21135,166,143 - 135,288,986 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,166,237 - 135,288,024 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,080,882 - 143,202,783 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01150,250,292 - 150,372,196 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,162,918 - 143,285,137 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01143,036,083 - 143,160,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,036,218 - 143,159,433 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01143,980,312 - 144,102,752 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,415,852 - 137,544,337 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,494,257 - 137,622,743 (+)NCBI
Celera1127,217,639 - 127,339,111 (+)NCBICelera
Cytogenetic Map1q31NCBI
Pde8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541614,063,123 - 14,125,220 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541614,063,117 - 14,204,297 (-)NCBIChiLan1.0ChiLan1.0
PDE8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21673,934,543 - 74,094,624 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11578,154,258 - 78,310,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01563,649,336 - 63,805,613 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11582,971,764 - 83,127,963 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1582,971,986 - 83,127,957 (+)Ensemblpanpan1.1panPan2
PDE8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,278,498 - 54,367,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,128,680 - 54,367,400 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha356,852,891 - 57,008,693 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0354,631,013 - 54,787,194 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl354,631,028 - 54,787,190 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1354,151,873 - 54,307,649 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0354,360,516 - 54,516,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0354,702,916 - 54,859,444 (+)NCBIUU_Cfam_GSD_1.0
Pde8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640129,171,415 - 129,324,830 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648317,095,318 - 17,163,114 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648317,009,696 - 17,163,105 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDE8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl752,410,779 - 52,557,645 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1752,410,766 - 52,558,482 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2757,896,426 - 57,969,573 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDE8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1293,214,183 - 3,367,051 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl293,213,165 - 3,367,571 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605943,694,868 - 43,851,671 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pde8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476818,180,061 - 18,352,830 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476818,180,066 - 18,352,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Pde8a
5715 total Variants

Predicted Target Of
Summary Value
Count of predictions:729
Count of miRNA genes:489
Interacting mature miRNAs:591
Transcripts:ENSMUST00000026672, ENSMUST00000128154, ENSMUST00000130494
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 60 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse

1 to 10 of 60 rows
RH136499  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,222,156 - 81,222,363UniSTSGRCm38
GRCm381135,301,711 - 135,301,919UniSTSGRCm38
MGSCv37788,367,042 - 88,367,249UniSTSGRCm37
MGSCv371137,198,288 - 137,198,496UniSTSGRCm37
Celera778,627,281 - 78,627,488UniSTS
Celera1137,926,776 - 137,926,984UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map1FUniSTS
AI551852  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,334,116 - 81,334,203UniSTSGRCm38
MGSCv37788,479,002 - 88,479,089UniSTSGRCm37
Celera778,739,290 - 78,739,377UniSTS
Cytogenetic Map7D3UniSTS
Whitehead/MRC_RH7759.79UniSTS
21.MMHAP17FRG9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,299,989 - 81,300,089UniSTSGRCm38
MGSCv37788,444,875 - 88,444,975UniSTSGRCm37
Celera778,705,042 - 78,705,142UniSTS
Cytogenetic Map7D3UniSTS
Whitehead_YAC7 UniSTS
RH143306  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,212,894 - 81,213,008UniSTSGRCm38
MGSCv37788,357,780 - 88,357,894UniSTSGRCm37
Celera778,618,039 - 78,618,153UniSTS
Cytogenetic Map7D3UniSTS
AF067806  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,333,779 - 81,333,894UniSTSGRCm38
MGSCv37788,478,665 - 88,478,780UniSTSGRCm37
Celera778,738,953 - 78,739,068UniSTS
Cytogenetic Map7D3UniSTS
Whitehead/MRC_RH7763.92UniSTS
Pde8a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37788,460,000 - 88,460,066UniSTSGRCm37
Celera778,720,158 - 78,720,224UniSTS
Cytogenetic Map7D3UniSTS
cM Map7 UniSTS
Pde8a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,315,114 - 81,315,180UniSTSGRCm38
MGSCv37788,460,000 - 88,460,066UniSTSGRCm37
Celera778,720,158 - 78,720,224UniSTS
Cytogenetic Map7D3UniSTS







Ensembl Acc Id: ENSMUST00000026672   ⟹   ENSMUSP00000026672
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl780,863,344 - 80,984,281 (+)Ensembl
GRCm38.p6 Ensembl781,213,596 - 81,334,533 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128154
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl780,945,455 - 80,964,935 (+)Ensembl
GRCm38.p6 Ensembl781,295,707 - 81,315,187 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl780,956,441 - 80,969,188 (+)Ensembl
GRCm38.p6 Ensembl781,306,693 - 81,319,440 (+)Ensembl
RefSeq Acc Id: NM_008803   ⟹   NP_032829
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39780,863,013 - 80,984,283 (+)NCBI
GRCm38781,213,265 - 81,334,535 (+)NCBI
MGSCv37788,358,690 - 88,478,508 (+)RGD
Celera778,686,223 - 78,738,796 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036152770   ⟹   XP_036008663
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39780,863,368 - 80,972,583 (+)NCBI
Sequence:
1 to 11 of 11 rows
Protein RefSeqs NP_032829 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008663 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40194 (Get FASTA)   NCBI Sequence Viewer  
  AAI25579 (Get FASTA)   NCBI Sequence Viewer  
  AAI32146 (Get FASTA)   NCBI Sequence Viewer  
  BAE28430 (Get FASTA)   NCBI Sequence Viewer  
  BAE28962 (Get FASTA)   NCBI Sequence Viewer  
  EDL06954 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000026672
  ENSMUSP00000026672.8
GenBank Protein O88502 (Get FASTA)   NCBI Sequence Viewer  
1 to 11 of 11 rows
RefSeq Acc Id: NP_032829   ⟸   NM_008803
- UniProtKB: Q059P6 (UniProtKB/Swiss-Prot),   O88502 (UniProtKB/Swiss-Prot),   Q3UFX9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000026672   ⟸   ENSMUST00000026672
RefSeq Acc Id: XP_036008663   ⟸   XM_036152770
- Peptide Label: isoform X1
PAC   PAS   PDEase

Name Modeler Protein Id AA Range Protein Structure
AF-O88502-F1-model_v2 AlphaFold O88502 1-823 view protein structure

RGD ID:8664611
Promoter ID:EPDNEW_M10337
Type:initiation region
Name:Pde8a_1
Description:Mus musculus phosphodiesterase 8A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38781,213,757 - 81,213,817EPDNEW
RGD ID:6841196
Promoter ID:MM_KWN:51327
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney
Transcripts:ENSMUST00000026672,   XM_001479535_GM4249
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36788,358,014 - 88,358,514 (+)MPROMDB
RGD ID:6841725
Promoter ID:MM_KWN:51330
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000060397
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36788,439,656 - 88,440,937 (+)MPROMDB


1 to 32 of 32 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000025584 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026672 ENTREZGENE
  ENSMUST00000026672.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1300.10 UniProtKB/Swiss-Prot
  3.40.50.2300 UniProtKB/Swiss-Prot
  PAS domain UniProtKB/Swiss-Prot
InterPro HD/PDEase_dom UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
  PAS-like_dom_sf UniProtKB/Swiss-Prot
  PDEase UniProtKB/Swiss-Prot
  PDEase_catalytic_dom UniProtKB/Swiss-Prot
  PDEase_catalytic_dom_sf UniProtKB/Swiss-Prot
  PDEase_CS UniProtKB/Swiss-Prot
KEGG Report mmu:18584 UniProtKB/Swiss-Prot
MGD MGI:1277116 ENTREZGENE
NCBI Gene 18584 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE PHOSPHODIESTERASE UniProtKB/Swiss-Prot
Pfam PAS_9 UniProtKB/Swiss-Prot
  PDEase_I UniProtKB/Swiss-Prot
PhenoGen Pde8a PhenoGen
PRINTS PDIESTERASE1 UniProtKB/Swiss-Prot
PROSITE PAS UniProtKB/Swiss-Prot
  PDEASE_I_1 UniProtKB/Swiss-Prot
  PDEASE_I_2 UniProtKB/Swiss-Prot
SMART HDc UniProtKB/Swiss-Prot
Superfamily-SCOP HD-domain/PDEase-like UniProtKB/Swiss-Prot
  SSF55785 UniProtKB/Swiss-Prot
UniProt O88502 ENTREZGENE, UniProtKB/Swiss-Prot
  Q059P6 ENTREZGENE
  Q3UEE9_MOUSE UniProtKB/TrEMBL
  Q3UFX9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q059P6 UniProtKB/Swiss-Prot
1 to 32 of 32 rows