TUBB4B (tubulin beta 4B class IVb) - Rat Genome Database

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Gene: TUBB4B (tubulin beta 4B class IVb) Sus scrofa
Analyze
Symbol: TUBB4B
Name: tubulin beta 4B class IVb
RGD ID: 14283182
Description: ENCODES a protein that exhibits double-stranded RNA binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN cytoskeleton organization (inferred); microtubule cytoskeleton organization (inferred); microtubule-based process (inferred); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN axonemal microtubule (inferred); cytoplasm (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin beta-4B chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,135,349 - 314,137,803 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TUBB4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,135,349 - 314,137,803 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TUBB4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,241,287 - 137,243,707 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,241,287 - 137,243,707 (+)EnsemblGRCh38hg38GRCh38
GRCh379140,135,739 - 140,138,159 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,255,532 - 139,257,980 (+)NCBINCBI36Build 36hg18NCBI36
Celera9110,651,151 - 110,653,744 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,595,024 - 109,597,472 (+)NCBIHuRef
CHM1_19140,284,445 - 140,286,893 (+)NCBICHM1_1
T2T-CHM13v2.09149,478,956 - 149,481,376 (+)NCBIT2T-CHM13v2.0
Tubb4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,112,170 - 25,114,714 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,112,172 - 25,114,714 (-)EnsemblGRCm39 Ensembl
GRCm38225,222,158 - 25,224,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,222,160 - 25,224,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,077,678 - 25,080,222 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,044,171 - 25,046,650 (-)NCBIMGSCv36mm8
Celera224,949,941 - 24,952,486 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.08NCBI
Tubb4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,435,999 - 28,438,455 (-)NCBIGRCr8
mRatBN7.238,037,838 - 8,040,294 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,037,799 - 8,040,296 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,142,521 - 11,144,977 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,728,750 - 19,731,206 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,918,593 - 17,921,049 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,441,585 - 2,444,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,441,733 - 2,444,281 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,422,868 - 2,425,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,387,050 - 3,389,500 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,387,049 - 3,389,500 (-)NCBI
Celera32,864,558 - 2,867,008 (-)NCBICelera
Cytogenetic Map3p13NCBI
Tubb4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,235,629 - 5,239,370 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,237,050 - 5,239,370 (+)NCBIChiLan1.0ChiLan1.0
TUBB4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,155,911 - 2,159,194 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,158,244 - 2,160,933 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,300,868 - 108,303,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,269,849 - 137,271,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,268,942 - 137,271,758 (+)Ensemblpanpan1.1panPan2
TUBB4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,432,114 - 48,434,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,427,766 - 48,571,640 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,618,435 - 47,620,948 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,293,272 - 49,295,782 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,289,395 - 49,295,750 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,069,677 - 48,072,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,368,505 - 48,371,015 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,415,650 - 48,418,163 (-)NCBIUU_Cfam_GSD_1.0
Tubb4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,623,429 - 202,625,856 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669749,202 - 751,739 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669749,203 - 751,622 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUBB4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112945,643 - 948,087 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12945,459 - 948,065 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660584,357,929 - 4,360,605 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tubb4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760712,987 - 717,951 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624760715,013 - 717,462 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 4 2 2 2 17 1 1
Low 6 2 3 3 6 2 2 2
Below cutoff

Sequence


Protein Domains
Tubulin/FtsZ 2-layer sandwich   Tubulin/FtsZ GTPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037046 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015077423 UniProtKB/TrEMBL
  ENSSSCG00025066544 UniProtKB/TrEMBL
  ENSSSCG00030055804 UniProtKB/TrEMBL
  ENSSSCG00035014450 UniProtKB/TrEMBL
  ENSSSCG00040045981 UniProtKB/TrEMBL
  ENSSSCG00050031080 UniProtKB/TrEMBL
  ENSSSCG00055000353 UniProtKB/TrEMBL
  ENSSSCG00065001773 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041019 ENTREZGENE
  ENSSSCT00000041019.3 UniProtKB/TrEMBL
  ENSSSCT00000043658.3 UniProtKB/TrEMBL
  ENSSSCT00000068510.2 UniProtKB/TrEMBL
  ENSSSCT00000078146.2 UniProtKB/TrEMBL
  ENSSSCT00000092551.1 UniProtKB/TrEMBL
  ENSSSCT00000097764.1 UniProtKB/TrEMBL
  ENSSSCT00000103420.1 UniProtKB/TrEMBL
  ENSSSCT00015104878.1 UniProtKB/TrEMBL
  ENSSSCT00015104997.1 UniProtKB/TrEMBL
  ENSSSCT00025091472.1 UniProtKB/TrEMBL
  ENSSSCT00025091594.1 UniProtKB/TrEMBL
  ENSSSCT00025091707.1 UniProtKB/TrEMBL
  ENSSSCT00025091806.1 UniProtKB/TrEMBL
  ENSSSCT00025091873.1 UniProtKB/TrEMBL
  ENSSSCT00030077796.1 UniProtKB/TrEMBL
  ENSSSCT00030077832.1 UniProtKB/TrEMBL
  ENSSSCT00030077856.1 UniProtKB/TrEMBL
  ENSSSCT00030077891.1 UniProtKB/TrEMBL
  ENSSSCT00030077901.1 UniProtKB/TrEMBL
  ENSSSCT00035018334.1 UniProtKB/TrEMBL
  ENSSSCT00035018360.1 UniProtKB/TrEMBL
  ENSSSCT00035018370.1 UniProtKB/TrEMBL
  ENSSSCT00035018383.1 UniProtKB/TrEMBL
  ENSSSCT00035018389.1 UniProtKB/TrEMBL
  ENSSSCT00040061898.1 UniProtKB/TrEMBL
  ENSSSCT00040061967.1 UniProtKB/TrEMBL
  ENSSSCT00040062123.1 UniProtKB/TrEMBL
  ENSSSCT00040062317.1 UniProtKB/TrEMBL
  ENSSSCT00050041930.1 UniProtKB/TrEMBL
  ENSSSCT00050041932.1 UniProtKB/TrEMBL
  ENSSSCT00055000662.1 UniProtKB/TrEMBL
  ENSSSCT00055000727.1 UniProtKB/TrEMBL
  ENSSSCT00055000779.1 UniProtKB/TrEMBL
  ENSSSCT00055000799.1 UniProtKB/TrEMBL
  ENSSSCT00055000815.1 UniProtKB/TrEMBL
  ENSSSCT00065002314.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.600 UniProtKB/TrEMBL
  3.30.1330.20 UniProtKB/TrEMBL
  3.40.50.1440 UniProtKB/TrEMBL
InterPro Beta-tubulin_BS UniProtKB/TrEMBL
  Beta_tubulin UniProtKB/TrEMBL
  Tub_FtsZ_C UniProtKB/TrEMBL
  Tubulin UniProtKB/TrEMBL
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/TrEMBL
  Tubulin/FtsZ_C_sf UniProtKB/TrEMBL
  Tubulin/FtsZ_GTPase_sf UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
  Tubulin_CS UniProtKB/TrEMBL
  Tubulin_FtsZ_GTPase UniProtKB/TrEMBL
KEGG Report ssc:100516352 UniProtKB/TrEMBL
NCBI Gene TUBB4B ENTREZGENE
PANTHER OS01G0282866 PROTEIN UniProtKB/TrEMBL
  PTHR11588 UniProtKB/TrEMBL
  TUBULIN BETA-4B CHAIN UniProtKB/TrEMBL
  TUBULIN DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Tubulin UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
PRINTS BETATUBULIN UniProtKB/TrEMBL
  TUBULIN UniProtKB/TrEMBL
PROSITE TUBULIN UniProtKB/TrEMBL
  TUBULIN_B_AUTOREG UniProtKB/TrEMBL
SMART Tubulin UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
Superfamily-SCOP SSF52490 UniProtKB/TrEMBL
  SSF55307 UniProtKB/TrEMBL
UniProt A0A287A217_PIG UniProtKB/TrEMBL
  A0A287A275_PIG UniProtKB/TrEMBL
  A0A480JIK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480VZN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2Q9J2_PIG UniProtKB/TrEMBL
  A0A5G2QGK1_PIG UniProtKB/TrEMBL
  A0A8D0T1I2_PIG UniProtKB/TrEMBL
  A0A8D0UDV4_PIG UniProtKB/TrEMBL
  A0A8D0UZ64_PIG UniProtKB/TrEMBL
  A0A8D0XJ36_PIG UniProtKB/TrEMBL
  A0A8D0XJF4_PIG UniProtKB/TrEMBL
  A0A8D0YW67_PIG UniProtKB/TrEMBL
  A0A8D1CCX7_PIG UniProtKB/TrEMBL
  A0A8D1CM98_PIG UniProtKB/TrEMBL
  A0A8D1PA48_PIG UniProtKB/TrEMBL
  A0A8D1PB36_PIG UniProtKB/TrEMBL
  A0A8D1X742 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FBW3_PIG UniProtKB/TrEMBL
  A0A8W4FEL0_PIG UniProtKB/TrEMBL
  A0A8W4FJ07_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94580 ENTREZGENE