CHRM1 (cholinergic receptor muscarinic 1) - Rat Genome Database

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Gene: CHRM1 (cholinergic receptor muscarinic 1) Sus scrofa
Analyze
Symbol: CHRM1
Name: cholinergic receptor muscarinic 1
RGD ID: 14227533
Description: ENCODES a protein that exhibits G protein-coupled acetylcholine receptor activity (ortholog); INVOLVED IN entrainment of circadian clock; G protein-coupled acetylcholine receptor signaling pathway; phototransduction, visible light; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH asthma (ortholog); brain ischemia (ortholog); epilepsy (ortholog); FOUND IN asymmetric synapse (ortholog); axon terminus (ortholog); cholinergic synapse (ortholog); INTERACTS WITH pirenzepine
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mAChR; muscarinic acetylcholine receptor M1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.128,858,765 - 8,872,042 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,210,975 - 8,225,464 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
pirenzepine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:3762692   PMID:12196552   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CHRM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.128,858,765 - 8,872,042 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,210,975 - 8,225,464 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,908,679 - 62,921,878 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,908,679 - 62,921,807 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,676,151 - 62,688,835 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,432,727 - 62,445,588 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,432,727 - 62,445,588NCBI
Celera1159,999,724 - 60,012,585 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1159,005,193 - 59,018,054 (-)NCBIHuRef
CHM1_11162,559,164 - 62,572,025 (-)NCBICHM1_1
T2T-CHM13v2.01162,898,039 - 62,911,241 (-)NCBIT2T-CHM13v2.0
Chrm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,641,369 - 8,660,970 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,641,153 - 8,660,951 (+)EnsemblGRCm39 Ensembl
GRCm38198,664,005 - 8,683,606 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,663,789 - 8,683,587 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,738,495 - 8,758,096 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,723,372 - 8,748,612 (+)NCBIMGSCv36mm8
Celera198,422,264 - 8,441,868 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.44NCBI
Chrm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81214,996,180 - 215,012,136 (+)NCBIGRCr8
mRatBN7.21205,567,226 - 205,583,001 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,567,220 - 205,582,356 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1213,986,616 - 213,987,998 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,024,093 - 221,025,475 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,716,796 - 213,718,178 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,869,087 - 224,885,101 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,882,439 - 224,884,205 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,806,335 - 231,822,359 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,351,738 - 211,353,120 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,510,167 - 211,511,550 (+)NCBI
Celera1203,093,639 - 203,095,021 (+)NCBICelera
Cytogenetic Map1q43NCBI
Chrm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599349,744 - 356,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599349,744 - 356,714 (+)NCBIChiLan1.0ChiLan1.0
CHRM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2964,131,197 - 64,143,870 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,176,365 - 65,189,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,261,476 - 58,274,685 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,612,934 - 61,626,767 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,614,818 - 61,616,200 (-)Ensemblpanpan1.1panPan2
CHRM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,783,938 - 53,797,750 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,795,326 - 53,796,708 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,389,834 - 52,403,632 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,835,906 - 54,849,703 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,833,743 - 54,849,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11853,933,197 - 53,947,176 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,507,453 - 53,521,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,299,342 - 54,313,140 (+)NCBIUU_Cfam_GSD_1.0
Chrm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,273,646 - 10,286,998 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581387,705 - 400,740 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581387,939 - 400,740 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1110,978,464 - 10,991,650 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl110,989,207 - 10,990,589 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,331,823 - 108,345,191 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,326,866 - 1,330,805 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,326,851 - 1,335,477 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHRM1
534 total Variants

Sequence


RefSeq Acc Id: NM_214034   ⟹   NP_999199
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.128,858,765 - 8,872,042 (+)NCBI
Sequence:
RefSeq Acc Id: NP_999199   ⟸   NM_214034
- UniProtKB: P04761 (UniProtKB/Swiss-Prot),   A0A4X1VMI7 (UniProtKB/TrEMBL)
- Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00015069309 UniProtKB/Swiss-Prot
  ENSSSCG00025074060 UniProtKB/Swiss-Prot
  ENSSSCG00030011943 UniProtKB/Swiss-Prot
  ENSSSCG00035045451 UniProtKB/Swiss-Prot
  ENSSSCG00040045082 UniProtKB/Swiss-Prot
  ENSSSCG00045033695 UniProtKB/Swiss-Prot
  ENSSSCG00050010499 UniProtKB/Swiss-Prot
  ENSSSCG00055004285 UniProtKB/Swiss-Prot
  ENSSSCG00060036236 UniProtKB/Swiss-Prot
  ENSSSCG00065007001 UniProtKB/Swiss-Prot
  ENSSSCG00070024997 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00015092787.1 UniProtKB/Swiss-Prot
  ENSSSCT00025101968.1 UniProtKB/Swiss-Prot
  ENSSSCT00025102004.1 UniProtKB/Swiss-Prot
  ENSSSCT00030016391.1 UniProtKB/Swiss-Prot
  ENSSSCT00030016402.1 UniProtKB/Swiss-Prot
  ENSSSCT00035060405.1 UniProtKB/Swiss-Prot
  ENSSSCT00035060408.1 UniProtKB/Swiss-Prot
  ENSSSCT00040060497.1 UniProtKB/Swiss-Prot
  ENSSSCT00040060566.1 UniProtKB/Swiss-Prot
  ENSSSCT00045057639.1 UniProtKB/Swiss-Prot
  ENSSSCT00045057669.1 UniProtKB/Swiss-Prot
  ENSSSCT00050014122.1 UniProtKB/Swiss-Prot
  ENSSSCT00050014128.1 UniProtKB/Swiss-Prot
  ENSSSCT00055008469.1 UniProtKB/Swiss-Prot
  ENSSSCT00055008473.1 UniProtKB/Swiss-Prot
  ENSSSCT00060049104.1 UniProtKB/Swiss-Prot
  ENSSSCT00060049109.1 UniProtKB/Swiss-Prot
  ENSSSCT00065009381.1 UniProtKB/Swiss-Prot
  ENSSSCT00065009386.1 UniProtKB/Swiss-Prot
  ENSSSCT00070049953.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Musac_Ach_M1_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Musac_Ach_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397099 UniProtKB/Swiss-Prot
NCBI Gene CHRM1 ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MUSCARINIC ACETYLCHOLINE RECEPTOR M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MUSCARINICR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MUSCRINICM1R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1VMI7 ENTREZGENE, UniProtKB/TrEMBL
  ACM1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:111797 ENTREZGENE