IRX5 (iroquois homeobox 5) - Rat Genome Database

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Gene: IRX5 (iroquois homeobox 5) Sus scrofa
Analyze
Symbol: IRX5
Name: iroquois homeobox 5
RGD ID: 14215050
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell development (ortholog); neuron maturation (ortholog); regulation of gene expression (ortholog); ASSOCIATED WITH anodontia (ortholog); Bone Fractures (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: iroquois-class homeodomain protein IRX-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl630,511,894 - 30,514,808 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1630,511,263 - 30,515,015 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IRX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl630,511,894 - 30,514,808 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1630,511,263 - 30,515,015 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IRX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381654,930,865 - 54,934,485 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1654,930,865 - 54,934,485 (+)EnsemblGRCh38hg38GRCh38
GRCh371654,964,777 - 54,968,397 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361653,522,612 - 53,525,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 341653,522,611 - 53,525,894NCBI
Celera1639,479,883 - 39,483,213 (+)NCBICelera
Cytogenetic Map16q12.2NCBI
HuRef1640,851,390 - 40,854,676 (+)NCBIHuRef
CHM1_11656,372,071 - 56,375,357 (+)NCBICHM1_1
T2T-CHM13v2.01660,728,978 - 60,732,598 (+)NCBIT2T-CHM13v2.0
Irx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39893,084,424 - 93,088,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl893,084,253 - 93,102,914 (+)EnsemblGRCm39 Ensembl
GRCm38892,357,796 - 92,361,456 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl892,357,625 - 92,376,286 (+)EnsemblGRCm38mm10GRCm38
MGSCv37894,881,695 - 94,885,355 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36895,246,924 - 95,250,584 (+)NCBIMGSCv36mm8
Celera896,669,925 - 96,673,589 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map844.93NCBI
Irx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81930,812,033 - 30,816,885 (-)NCBIGRCr8
mRatBN7.21914,639,052 - 14,643,911 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1914,624,225 - 14,642,318 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1916,335,573 - 16,338,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01921,530,376 - 21,533,070 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01924,476,554 - 24,479,248 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01916,415,813 - 16,421,088 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1916,415,636 - 16,421,191 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01927,490,017 - 27,494,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41915,747,720 - 15,750,414 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1914,553,091 - 14,555,785 (-)NCBICelera
Cytogenetic Map19p11NCBI
Irx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543312,519,338 - 12,522,118 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543312,518,786 - 12,522,744 (+)NCBIChiLan1.0ChiLan1.0
IRX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21864,359,486 - 64,363,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11670,278,544 - 70,282,165 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01635,164,884 - 35,168,189 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11654,272,272 - 54,275,431 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1654,272,412 - 54,275,124 (+)Ensemblpanpan1.1panPan2
IRX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1260,957,353 - 60,978,782 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl260,968,193 - 61,041,385 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha257,609,385 - 57,612,765 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,516,686 - 61,520,066 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,509,877 - 61,582,135 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1258,341,971 - 58,345,349 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0259,367,066 - 59,370,437 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0260,245,608 - 60,248,977 (-)NCBIUU_Cfam_GSD_1.0
Irx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934952,231,182 - 52,234,905 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364757,354,642 - 7,358,553 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364757,354,273 - 7,358,328 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1540,705,061 - 40,708,749 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604735,643,147 - 35,667,057 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247571,947,032 - 1,966,352 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247571,962,574 - 1,966,330 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IRX5
23 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
2 2 11 1 7 5 11 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021094164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000042364   ⟹   ENSSSCP00000032113
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl630,511,894 - 30,514,808 (-)Ensembl
RefSeq Acc Id: XM_021094164   ⟹   XP_020949823
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1630,511,263 - 30,515,015 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020949823   ⟸   XM_021094164
- UniProtKB: A0A286ZKM7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000032113   ⟸   ENSSSCT00000042364
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025064371 UniProtKB/TrEMBL
  ENSSSCG00030031403 UniProtKB/TrEMBL
  ENSSSCG00035047941 UniProtKB/TrEMBL
  ENSSSCG00040050575 UniProtKB/TrEMBL
  ENSSSCG00045023773 UniProtKB/TrEMBL
  ENSSSCG00055008441 UniProtKB/TrEMBL
  ENSSSCG00060064312 UniProtKB/TrEMBL
  ENSSSCG00065006534 UniProtKB/TrEMBL
  ENSSSCG00070015170 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042364 ENTREZGENE
  ENSSSCT00000042364.3 UniProtKB/TrEMBL
  ENSSSCT00025088248.1 UniProtKB/TrEMBL
  ENSSSCT00030043507.1 UniProtKB/TrEMBL
  ENSSSCT00035063847.1 UniProtKB/TrEMBL
  ENSSSCT00040068268.1 UniProtKB/TrEMBL
  ENSSSCT00045040629.1 UniProtKB/TrEMBL
  ENSSSCT00055016488.1 UniProtKB/TrEMBL
  ENSSSCT00060087790.1 UniProtKB/TrEMBL
  ENSSSCT00065008792.1 UniProtKB/TrEMBL
  ENSSSCT00070029797.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  Iroquois_homeo UniProtKB/TrEMBL
NCBI Gene IRX5 ENTREZGENE
PANTHER IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX UniProtKB/TrEMBL
  IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  IRO UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A286ZKM7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U574_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89219 ENTREZGENE