Advanced Search (OLGA)

Gene: SSPO (SCO-spondin) Sus scrofa

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Symbol:

SSPO

Name:

SCO-spondin

RGD ID:

14180985

Description:

ENCODES a protein that exhibits peptidase inhibitor activity (inferred); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; Notch signaling pathway; FOUND IN cytoplasm (ortholog); INTERACTS WITH deoxynivalenol; graphene oxide

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

SCO-spondin, pseudogene; SSPOP

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SSPOP (SCO-spondin, pseudogene)	HGNC	Ensembl, NCBI, OrthoDB
Mus musculus (house mouse):	Sspo (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sspo (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sspo (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SSPOP (SCO-spondin, pseudogene)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SSPO (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101972385 (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103227202 (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sspo (SCO-spondin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	18	55,783,659 - 55,839,167 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

graphene oxide (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (ISO)

extracellular matrix (IBA)

extracellular region (IEA)

Molecular Function

extracellular matrix structural constituent (IBA)

peptidase inhibitor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Hedgehog signaling pathway (ISO)

mTOR signaling pathway (ISO)

Notch signaling pathway (ISO)

nuclear factor kappa B signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SSPO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	18	55,783,659 - 55,839,167 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SSPOP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	149,776,042 - 149,833,965 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	149,776,042 - 149,833,829 (+)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	7	149,473,131 - 149,531,054 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	149,104,064 - 149,161,987 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	7	144,142,344 - 144,200,269 (+)	NCBI		Celera
Cytogenetic Map	7	q36.1	NCBI
HuRef	7	143,549,056 - 143,606,500 (+)	NCBI		HuRef
CHM1_1	7	149,481,703 - 149,539,633 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	150,957,942 - 151,015,873 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	148,811,145 - 148,869,073 (+)	NCBI

Sspo
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	48,423,164 - 48,478,196 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	48,425,163 - 48,478,184 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	48,446,230 - 48,501,262 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	48,448,229 - 48,501,250 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	6	48,398,228 - 48,451,249 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	48,377,815 - 48,430,821 (+)	NCBI		MGSCv36	mm8
Celera	6	48,952,263 - 49,005,530 (+)	NCBI		Celera
Cytogenetic Map	6	B2.3	NCBI
cM Map	6	23.42	NCBI

Sspo
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	78,725,829 - 78,781,330 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	78,727,275 - 78,781,315 (+)	Ensembl				GRCr8
mRatBN7.2	4	77,394,915 - 77,450,526 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	77,397,059 - 77,450,412 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	82,604,065 - 82,657,564 (+)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	78,379,570 - 78,433,071 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	76,819,843 - 76,873,346 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	4	79,976,284 - 80,029,652 (+)	NCBI
Lyon_Normotensive	4	77,659,527 - 77,712,879 (+)	NCBI
Lyon_Hypertensive	4	78,176,459 - 78,229,817 (+)	NCBI
F344_StmMcwi	4	78,075,718 - 78,129,033 (+)	NCBI
Rnor_6.0	4	78,076,695 - 78,133,676 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	78,080,310 - 78,133,654 (+)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	4	142,741,801 - 142,797,367 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	76,533,300 - 76,587,372 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	72,334,747 - 72,387,924 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Sspo
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955491	4,840,657 - 4,888,929 (+)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955491	4,840,657 - 4,889,060 (+)	NCBI	ChiLan1.0	ChiLan1.0

SSPOP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	186,333,198 - 186,390,593 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	38,343,462 - 38,400,857 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	141,477,578 - 141,537,109 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	153,952,527 - 154,009,016 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

SSPO
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	14,547,529 - 14,599,163 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	14,548,097 - 14,599,147 (+)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	15,156,808 - 15,207,847 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	16,262,986 - 16,314,042 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	16,262,986 - 16,314,042 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	14,643,044 - 14,694,009 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	15,223,874 - 15,274,902 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	15,274,039 - 15,325,105 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC101972385
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	2	225,204,755 - 225,260,151 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024405118	7,028,434 - 7,081,083 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	5,824,319 - 5,874,879 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	5,821,533 - 5,874,995 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC103227202
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	21	122,804,637 - 122,866,675 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666072	14,298,648 - 14,359,362 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	21	118,339,676 - 118,399,716 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2

Sspo
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624800	6,196,413 - 6,242,808 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in SSPO
903 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021078747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_085005017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	GFLN01109329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JBREVY020000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021078747 ⟹ XP_020934406

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	18	55,783,659 - 55,839,167 (+)	NCBI

Sequence:

show sequence

GAGGGGGCGTGTTCAGGGGCGGGAGGCCGTGCCTGCGCTGCGGGCTCAGAATCGCGGGCGCCCG
CCGGGAGTGTGTCTGCGCCGCGCTCCCGCGACGGGATCTAGTCTCCCGACTGTCGGTTGGTGGG
GTCGGTCTGGGAAACTCCGGGCCAGCCCCTACTCTCCACCTGGATCCCCCCAGACCCGCACCCC
CCCGCATCCTGATCGGAGAGCTCAAAGGAGACCAGTCGGGGCCCCAGTGCGCTCCAAGAACGGG
CTCTTCCAAGTAGAAATTGGGATGGGGGCTTTGAACCAGGTCCCCTGGGAGAAGGCAGGGCTGG
ACGGGAGGCGGTGGGGAGTGAGGCAGGAGTGGAGCACGGTGACGACTCCAACTGCGGGGTCCCG
GGGAGCCCGCCGGCGGGAGGAGAGAGTTCCCTGGAGGTGCTGGGGGAGGGGCGGGTCCCTCTGC
CGCCCGGGAACCTCTGCCCTCAGGTGTCCCTGCCCCAGGGCTCTGATGCCCCTCTTCAAAACGC
AGCGGGGGCACATCTGTATTTGTTGATGTTGAGGGTGAGAGGCTCGGCAAGGGAGGGTTCCTCG
AAACCCACTGTGAACGGTTCTTCCACCTTCTGCCTGGCCTGCTCAGTAGCCCTCGGGAGGGTCC
AGGAAGAAGAACACGGCACTGTGTGCACCTGTGTCTGTCCTTTTAAGACCTGCAGTGCGAGTGT
AAATTGTGAGGTGCCTGGGGAGAGTGTCCAGGCGTGCGTGTGTGAGAGACTGGCAAGAGCAGAG
TGTCTGACTCGGGACCCTTCTGAGGGCACCATCCTTCCCAAGGGACCCACTGCACCTTCTCTTG
GCTCAGAACCAACGGTGGGACCAGAAGTATGGCTGGCGTGGCTGTGGTTCCTGGCAGCCCCCCA
CCCCACAGGCGATGGTGCAAGCGGACAGAGACCATCTGGGTGGAGGAGGAAGTAACCCCCCGTC
AGGAGGACCTGGTGCCCTGCACCAGCCTCTCCCATTACCAGCGCCGGGGCTGGCGGCTGGACCT
GACCTGGAGTGGCCACGAGGGGCTCTGCCCCATCTACAAGCCCCCAGAAACCCGGCCTGCGGCA
TGGAACCGGACAGTGAGGGTTTGCTGCCCCGGCTGGGGGGGCCCCCACTGCACCCTGGCCCTTG
CAGAAACCAGCCCTGAGGGCCACTGCTTTGCCACAGGGCTGTGCCAGCTGCGGGCAGGCTCAGC
GAATGCCTCTGCAGGAAGCCTGGAGGAGTGCTGTGCCCAGCCCTGGGGACAAAGCTGGCAGGAT
GGCCGCTCCCAGGCGTGCCTCAGCTGCTCCAGCCACCAACTCCCAGGCACTGTGCCCTCTCCAG
CCCTCCTGCAGCCCCTGGCAGGGGCCGTGGCCCAACTCTGGAGCCAGCGCCAGCGTCCCTCAGC
CACCTGCGCCACCTGGTCAGGCTTCCACTATCGCACCTTTGACAGACGCCACTACCACTTCCTG
GGCCGCTGCACCTACCTGTTGGCGGGCGCTGCAGATTCCACTTGGGCTGTCCACCTCGAGCCCA
GGGGGCACTGCCCCCAGCCTGGGCACTGCCAGCTGGCCCGGGTGATGATGGGACCAGAGGAGGT
GCTGGTCCGGGGCAGAAACGTCTCTGTAAATGGGCAGCTGTTACCTGATGGGGAGTCTCAGCTG
CTCCCAGGGCTGAGCCTGCAGTGGCAAGGGGACTGGCTGGTGCTGTCAGGGGGACTGGGGGTCG
TTGTGCGGCTGGACGGGTCCAGTTCCGTCTCCATTTCCGTGGACCATGAGCTCCAGGGACAGAC
TCAAGGCCTCTGTGGGGTCTACAATGGCCAGCCTGAGGATGACTTCTTGGAGCCTGGCAGGAGA
CTGGCTGGGTTAGCTGCCACCTTTGGGAATTCCTGGAGGCTCCCAGACTCAGAGCCTGGGTGTC
TGGATGCAGTGGAGGCAGCCCAAGGCTGCGAGGACCCCCTGAGAGGCACAGAGGCGGGCATGGA
GCCTGGCCAGCTTCAGGCTGAAGCCCAGGATGTGTGCCACCAGCTGCTGGACAGTCCATTCAGG
GACTGCCATGTCCAGGTGCCCCCTGCTGAGTACCACGAGGCCTGCCTCTTTGCCTACTGTGCTG
CGGCCCCCGCGGGCAGCGGGCGGGAGGAGCGGCTGGAGGCCATCTGTGCCACCTTGGCCAACTA
TGCCCAGGACTGCGCGGCGCGGCGCGTCCTCCTGCGCTGGAGGAAGCCCGGCTTCTGCGAGCGC
CAGTGCCCGGGGGGCCAGCTGTACTCGGACTGCGCCTCGGCCTGCCCGCCCAGCTGCTCGGCAG
TGGACGACGGAGGCGAGGGGTCCTGCGGGGAGGAGTGCGTGAGCGGCTGCGAGTGCCCGCCCGG
CCTCTTCTGGGACGGCGCCGTCTGCGTGCCCGCCGCCCGCTGCCCCTGCTACCACCGACGCCGG
CGTTACAACCCCGGTGACACCGTGCGCCAGCTGTGCAACCCGTGTGTGTGCCAAGACGGCCGCT
GGCTCTGCGCGCAGGCGCCGTGCCCCGCCGAGTGCGCGGTGGGCGGGGACGGGCATTACCTCAC
CTTCGATGGGCGGAGCTTCTTCTTCCGCGGCGGCCCGGGTTGCGGCTCCAGGCTGGTGCAGGAC
TTTGTGAAGAGGGAGCTGCTGATTGTTCTGGAGCATGGGGACTGCGACTCTGGGAACTGCCTCC
GTGCCATCTCTGTCACCCTGGGGGACACCCACGTCCAGCTCAGGGACTCAGGAGCAGTACTGGT
CGATGGGCAGGATGTGGGCCTGCCCTGGAGTGGTGCTGGGGGCCTCAGCATCACCCGTGCCTCG
TCCACCTTCCTGCTGCTGCGCTGGCCTGGGGCCCACGTCCTCTGGGGCACATCGGACCCTGCAG
CCTACATCACCCTGGATCCCCGCCATGCCCACCAGGTGCAGGGTCTGTGTGGCACCTTCACCTG
GAACCAGCAGGATGACTTCCTGACACCCACTGGAGATGTGGAGACCAGTGTTGCAGCCTTTGCT
AGCAAGTTCCAAGTGGCAGGTGAGGGAAGGTGTCCTTCGGAGGAAGACAGCACCTCACTTTCCC
CCTGCAGCACCCATGCTCAGAGCCGTGTTTTCGCGGAAGCAGCCTGCGCCATCCTGCATGGCCC
AGCCTTCCAGGAGTGCCATGGGCTAGTGGACAGGGAGCCATTCCACCTGCGCTGCTTGGCAGCT
GTGTGCAGCTGTGCCCCCGGCAGAGACTGCCTGTGCCCTGTGCTCGCTGCCTATGCTCGGCGCT
GTGCCCAGGAGGGTGCCCTGCCTTCCTGGAGAAACCAGAGCCTCTGCCCTGTCCTGTGTCCTGG
TGGCCAGGAGTACCAGGAGTGTGCCCCAGCCTGCGGCCAGAACTGTGGGGAGCCAGAAGACTGT
GGGGAGCTGGGCACCTGTGTGGCTGGTTGTAATTGCCCCCTGGGGCTGCTGTGGGACCCCGAGG
GCCAGTGTGTGCCCCCTAGCTTGTGTCCCTGCCAGCTTGGGGACCATCGCTATGCCCCTGGCAG
TGCCGTCAGGAAGGACTGCAACCACTGTGTCTGCCGGGAGAGGGGACTCTGGAATTGCACTGCT
CACCACTGTGCCCCTGAGCGGGCCTTCTGCCCTGGCGAGCTTGTCTATGTCCCTGGTGCCTGCC
TCCTTACCTGTGACAACCCCCATGCCAACGGCTCCTGCCCACCAGGCAGCATGGGGGGCTGTGT
CTGTCCCCCGGGCAACGTGCTGCTGGATGAGCGCTGCGTCCATCCCGAGCTCTGTCCCTGCCGT
CACGGTGGCCAGTGGTACCCTCCCAATGCCACAATCCAGGAGGACTGCAACATGTGTGTGTGCC
AGGGCCGTCAGTGGCACTGCACAGGCCAGCGGTGTGATGGACGGTGCCAGGCATCAGGTGCCCC
CCACTATGTGACATTTGATGGCCTGGCCTTCACCTTCCCTGGGGCCTGCGAGTACCTGCTGCTG
CGAGAGGCCGACGGCCAGTTTACAGTCTCTGCCCAGAACCTGCCCTGCGGGGCCAGTGGCCTCA
CCTGCACCAAGGCGCTGACCGTGCGGCTGCAGAGCGCTGTTGTGCACATGCTCAGAGGCCAGGC
GGTGACAGTGAATGGGGTGAGTGTGACGCCTCCCAAGGTCTACACTGGCCCTGGGCTGAGCCTG
CACCGAGCCGGCCTCTTTCTGCTGCTCACCACCCGCCTGGGCCTCACCCTTCTCTGGGATGGAG
GCACCCGGGTCCTGGTACAGCTGTCCCCCCAGTTCCATGGCCGGGTGGCTGGGCTGTGTGGAGA
CTTTGATGGAGACGCCAGCAATGACCTTCGGAGCCGCCAGGGAGTCCTGGAGCCCACGGCCGAA
CTGGCTGCCCACTCATGGCGCCTCAATCCTCTCTGCCCTGAGCCAGGGGACCTGCCGTACCCCT
GCACTGTGAATGCCCACCGGGCCGGCTGGGCCCGTGCCCGCTGTGGGGTGTTGCTGCAGCCCCT
CTTTGCCCAGTGCCATGCGGAGGTGCCCCCACAGCGACACTATGAGTGGTGTGTGTATGACACC
TGCGGCTGTGATGCAGGCGGCGACTGTGAGTGTCTCTGCTCCGCCATTGCCACCTATGCCGACG
AGTGTGCCCGGCATGGGCTCCATGTGCGCTGGCGCAGCCAGGAACTCTGCCGTGAGTGTGCCCG
GCCCTTGGTCCCTGGAATCCAATCCCTCCACTCGCTCAGCTCCCTCAAGGACACCTCTCCCGGC
CTGAGAGCCATTCACTCGCTCAAGGGCAGATACACGTGGAATGTCCCATGCGCTAGACACCTTC
CTATGGACCAGACTTGCCCAAATCCCTGCTCTGTGGAACTTGCTTGTTGCACACAGCCTTGGGA
GGGGCCCAGCAAGAGGCCACATGCACCCCCGTGCCCTCCTCAGGTGTCACCTTCGGTTGGCTCG
CCTGCTGCTGTTGCATCCTGGTGCCCTGGCAGTGACCCAAGCCTCTCCCCTCTCCACCCAGCTC
TGCAGTGTGAAGGGGGTCAGGTGTATGAGGCTTGTGGCCCCACGTGTCCCCCCACCTGTCACGA
CCGCGGTCTGGAGCCTGGGTGGCACTGCCAAGCTGTGGCCTGTGTGGAGGGCTGTTTCTGCCCA
GAGGGGACTCTATTGCATGGAGGAGTCTGTCTGGAGCCAGCGTCCTGCCCCTGCGAGTGGGGCG
GCAGCTTCTTCCCACCGGGCACTGTGCTGCAGAAGGACTGTGGCAACTGCACGTGCCAGGAAAG
TCAATGGCTTTGTGGGGAGGATGGTAGCCACTGTGAGGAGCTGGTGCCTGGCTGTGCAGAGGGA
GAGGTGCCATGCCAGGAGAGCGGGCACTGTGTGCCACACAGCTGGCTTTGTGACAACCAGGATG
ACTGCGGTGACGGCTCAGACGAGGCGGGCTGTGCCACCCCAGGCTGTGGGGAGGGGCAGATGTC
TTGCAGCTCTGGCCACTGCCTGCCCCTGGCCCTGCTCTGTGATGGACGGGATGACTGTGAGGAT
GGGATGGATGAGCAGGGCTGCCCATGCCCCCCAGACTCACTGCCCTGTGCTGATGGGCGCTGCC
TGCCCCTGGCCCTGCTCTGCGATGGGCATCCGGACTGTCCAGATGCTGCTGACGAGGAGTCTTG
TCTGGGGCAAGTCAGCTGCACCCCTGGGGAGGTGTCCTGCGTCGATGGCGCCTGCGTGGGGGCC
CTCCGGCTGTGTGACGGAATCTGGGACTGCCCAAACGGAGCCGACGAGGGGCCTGGGCACTGCC
CCCTCCCCTCTCTGCCCATGCCGCCTGCTGGCACCTTGCCTGGCCTTTCCACTGCCTCCCAGGG
GACTCCACCAACTCCCCCTGCCAGGGTCAGCCCTGCGCCGCCCTGCGGCCCCTTGGACATCGCG
TGCGGCAGCGGCGAGTGCGCGCCCCGGGGCTGGCGCTGCGACGGCGAGGAGGACTGCGCCGACG
GCAGCGACGAGCACGGCTGCGGCTGGCCCTGCGCGCCGCCCCACGCGCCCTGCGCCCGCGGCCC
GCTCTGCGTGGCACCTGCGCAGCTGTGCGACGGCGTCCCGCACTGCCCCGACGGCTGGGACGAG
AGCCCTGGCGCCTGCGAGGGGCTGCCAGCCCCAGGAGGCCCCAATGGGACTGGAGTTCCCTGCT
CAGAATACTCCTGCCCGGATGGCCTCTGCATCGGTTTCCAGCAGGTGTGCAACGGGCAGCCTGA
CTGTGAATTGGCAGGGGAGGTGGGGTCCTCACCGGAAGAGCAGGGCTGTGGAGCCTGGGGCCCC
TGGAGCCCATGGGGGCCATGCAGCCAGACCTGTGGGCCTGGGGTACAGGCCCGGAGCCGCCGCT
GCTCCCCTCCCAGCCTCCCAGTGCTGCAGCACTGCCTGGGTCCCGAGCATCAGACTCAGGCCTG
CTTCACTGCCGCCTGCCCAGTGGATGCAGAATGGACTTCCTGGTCCCCCTGGTCCCCGTGCTCT
GAGCCATGCAGGGGCACCAGGACCCGGCAGCGACAGTGCCACCCACCCCAGAACGGGGGCCGGA
CCTGTGCCATGCTGCCCGGGGACCCTCACGGCACCCACCAGACTGGGCCCTGCCCTCAGGATGG
CTGCCCCAATGTCACCTGCTCCAGGGAGCTGGTGTTCCATCCCTGTGCCCCTTGCCCTTTGACT
TGTGATGACATCTCTGGTCAGGCCGTGTGCCCCCCTGACCCACCCTGCAGCAGCCCAGGCTGCT
GGTGCCCTACAGGGCAGGTGCTGGATGACAAAGGGCGGTGCGTGTGGCCTGGGCAGTGCCCCTG
CCTGGTGGACGGCATCCACTACCCACCAGGGCAGCGCATCAAGGCCGACTGCCAGCTCTGCATC
TGCCAAGATGGGCGGCCCCGGCGCTGCCGGCCCAACCTGGACTGTGCCGTGAACTGTGGCTGGT
CACTCTGGTCCCCCTGGGCTGAGTGCCTGGGTCCCTGCGGGAGCCTGAGCATTCAGTGGTCCTT
CCGAAGCCCCAACAACCCCCGCCTCTCTGGCCGAGGCCACCAGTGCCGGGGCATCCACCGCAAG
GCCCGCAGGTGCCAGACGAGGCCCTGTGGGGGCTGTGAGCAGCACGGCCAGGTCCACCGTGTTG
GGGAGCGCTGGCGAGGGGGCCCCTGCAAGGTCTGCCAGTGTCTGCACAATGGCACGGCCCACTG
CTCCCCCTACTGCCCGCTGGGCAGCTGCCCCCAGGACTGGGTTCTGGTGGAAGGAGTGGGAGAG
TCGTGTTGCCACTGCGCCCCTCCTGGAGTGAACTGGACGGTCCAGCCCATGGCCACTCCCGGCC
CCACTCCAGCCCCCAGCCCCCAGATCGGACCCTCTCTGATCACCTATGTTCTGCCTCCCCCTGG
CGACTCCTGCTATTCTCGCCTGGACCTGACCCGGCTCCCCAAGGGGAGCCTACAGGCTTCACCC
CAGCTGCTGGACCAGCCCACAGGGGAGCCTGGCCAGCAGACCTGGAGCCCTGCAGAGGCTGGTG
ACCTTCTGCGCCACATGCAGGCCCCCTATTTGCAGCTGGACCTGCTTCGGCCCCGGAACCTCAC
TGGCATCATGGTGCAGGGGGCGGGATCCTCAGACTTGCTCCAGTTCAGCAGTGATGGTCTACAC
TGGCACAGCTATCGTGACCTCCTGCCTGCCATTCAGCCGCCCCTCAAGCTTTTCCCTGGGACCC
GGGATGACGTGGCCCCCACCGTGTGGCTATTTGGCCGGATGGTGCAGGCTCGGCACGTCCGTGT
GTGGTCCCTCGACGTCACTCGCGGCCCCGAAAGTGATGTCAACCACAGCATCCCCCTGCAGGTG
GAGCTGCTCGGTTGTGAGCCAGCACCTGCCTGCCCAGGGGCTGGGCACCGCTGTGCCAGTGGCT
CGTGTGTCCTGAGAGGGACCCTGTGTGATGGTGTGGAAGATTGCGAGGATGGCTCCGATGAGGA
GGGCTGTGTGCCCCCGCCCACGGGCACTGCCAGAGTCCAGTCCACAGCCCGGACCCCGGCCCTT
TACCACACCCAGCCTGGATGGCTGCACCCCCAGCCCATGGAGGGTCTGGCAGAGACTGAGCGCT
GGCATCCCAGGCAGGGGTCACCCCCGCCCCCCACAGGAAAGTGGCCAGCAAGTCTTGTGTCCGC
GTCTCCCCCAAGTCCTGAGGACTTTGTGCAGACCGCACCTGCCACCCCCACGTCCCGGCCTGAG
GTGACAACCCCGAGACCCGAAATGGCAGCCGTGACGGTGCTTCCCCCACACCCAACGATGTCTG
TGGCCCGTGATGGACACAGCATCGCCCCAGCGCCCTTCCCACCCATGCGGTGCCGCCTGGGCCA
GGTGCCCTGCAAGGTGCTGGGCTGCATGGAGCAAGAGCAGCTGTGTGACGGGAAGGAGGACTGT
CTGGATGGCTCTGACGAGAGGTCCTGCGGGCTCAGTTTATCATTCAGCTGGAATCACGTGTGTG
ACCCTGTTCCCCCACCTCCGCCTGCAGCATGGGCAGGGGGCACTGTGCCCTTTACAGTGCCCAC
CACGGCCCTACCTGGGCTGCCGGCCTCCAGAGCCCTCTGCTCCCCGAGCCAGCTGAGCTGCGGC
AGTGGGGAGTGCCTGCCCGCCGAGCGGCGCTGTGACCTGCAGCCCGACTGCCAGGACGGCTCAG
ATGAAGACGGCTGTGTGGACTGTGGCCTGGCGCCCTGGTCAGGCTGGAGCAGCTGCAGCCACAG
CTGTGGCCTGGGCCTCGCCTTCCAGCGCCGGGAGCTGCAGCGGCCTCCACTGCCTGGCGGCAGC
TGCCCGCCAGATCGGCTCCGCAGCCGGTCCTGCTTTGTGCGGGCCTGCCCAGTGGCTGGGGCGT
GGGCTGAGTGGGAGGCCTGGGGGCCCTGCAGCGTCTCTTGCGGGGGTGGCCATCGGAGTCGCCG
GCGGAGCTGTGTGGACCCCCCACCCAAGAATGGCGGCGCCCCCTGCCCTGGGGCCTCCCAAGAG
GGGGCGCCCTGCGGCTTGCAGTCCTGCACAGGTGGCACAGACTGCGGGCTGGGCCGTGTGCATG
TTAGTGAGGAAATGTGCCAGAAGGGGCTGGTGCCCCCGTGCCCCCCCTCCTGCCTGGACCCGGA
GGCCAACAGAAGCTGCAGCGGACACTGTCTGGAGGGATGCCGCTGCCCGCCTGGGCTCCTCCTC
CAGGACACCCGCTGCCTGCCCCTCTCCGAGTGCCCTTGCCTTGTGGGTGAAGAGCTGCAGCAGC
CAGGGCAGCCCTTCCTCCTGGACAACTGCAGCCGATGCATGTGCCAGAAGGGGGCTCTGCTGTG
TGAACCAGGGGGCTGCCCTATGCCCTGCGGCTGGTCAGCCTGGTCCTCCTGGGGTCCCTGCGAC
CGCTCCTGTGGCTCTGGCTTGAGGGCCAGGTTCAGGTCCCCCTCCAACCCTCCGGCCGCTTCGG
GGGGTGCCCCATGTGAAGGCGAAAGGCAGGAGCTGCAGGCCTGTCACTTGTCGACGTGTGGGGC
AGAGCCGCTGGGCTGGACGCCCTGGACACCCTGGTCCACCTGCTCCCAGAGCTGCCTTGTCCCT
GGAGGGGGCCCAGGCTGGCGCAGCCGTTCCCGGCTCTGTCCCAGCCCCAGCAACATGTCCTGCC
CAGGAGAGGCCATCCAGGAGGAGCCCTGCAGCCCCCTGGTGTGCCCAGTGGCCAGCATCTGGGG
TCTGTGGGCCGCTTGGTCCACCTGCTCGGCCCCTTGTGATGGAGGCATCCAGACACGTGGACGC
AGCTGCCCTGCCTTGGCTCCTGGGAACCCTGGGTGCCATGGACCCCACAGCCAGACGAGGGACT
GCAATATGCAGCCCTGCACAGCCCAGTGCCCAGAGGACATGGTGTTCCGCTCGGCGGAGCAGTG
CCGCCAGGAGGGGGGGCCGTGCCCTCGGCTGTGCCTGGCGCAGGGTCCTGGGGTGGAGTGCTCC
GGCCTCTGCAGCCCTGGCTGTACCTGCCCCCCTGGTCTCTTCCTGCACAACGCCAGTTGCCTGC
CCCTCAGTCAGTGCCCCTGCCAGCTGCGTGGGCAGCTCTATGCACCAGGAGCAGTGGCCCGGCT
GGACTCCTGCAACAATTGCACCTGCATCTCTGCTGAGATGGTGTGCACCTCGGAGCCCTGCCCA
GTGGCCTGTGGCTGGAGCCCCTGGACCCCGTGGAGTCTCTGCAGCCGCAGCTGTGATGTGGGCA
TTCGGCGGCGCTTCCGGGCGGGCACTGCACCCCCAGCTGCCTTTGGGGGGCCTTCATGCCAGGG
TCCCAACGTGGAGGCTGAATTCTGCAGCCTGCAGCCATGCCAGGGTCCTGGCGAGGAGTGGGGC
CCCTGGTCTCCGTGCTCCGTGCCCTGTGGCGGTGGCTACCGGAATCGCACCCGAGGGGGCAGCG
GGCACAGCCCCGTGGACTTCTCCACCTGCAGCCTGCAGCCCTGTGCAGGACCAGTACCCGGTGT
GTGTCCTCCGGGCAAGCGATGGCTGGACTGTGCCCAGGGCCCTGCCTCCTGTGCAGAGCTCAGC
ACCCCGAGAGGGACTGACCAGCCCTGCCACGCCGGCTGCTACTGCCTGCCCGGGATGCTCTTGT
TGAACAACGTGTGTGTGCCCACCCAGGACTGCCCCTGCACCCACGGGGGTCGCCTCCACCCCCC
GGGCAGTGCTGTGCTTCGTCCATGTGAGAATTGCTCCTGTGTCTCTGGGCTTGTCACCAACTGC
ACGGCCTGGCCCTGTGAGGAGGCTCGGCCCACGTGGTCACCCTGGACCCCATGGAGCGAGTGTT
CTGCCTCCTGTGGCCCTGCCCACCGCCACCGGCACCGCTTCTGCCCCAGGCCCCCCAGCGTGGC
ACAGCCGCCCCCATCGGCCTCACCTCCACTTCCTTGCCCTGGCCTTGAGGCAGACGAGGAGCCC
TGCCTCCTGCCAGCGTGTGACCGAGCTGGAGCCTGGGGCCCTTGGGGGCCCTGGTCCAGCTGTA
GCCGGAGCTGTGGGGGCGGCCTTTGGAGCCGGACCCGAGCCTGTGACCAGCCCCCGCCCCAGGG
CCTGGGGGATTACTGCGAGGGGCCTCGGGCCCAGGGCGCCGCCTGCCAGGTTCTGCCCTGCCCA
GGTGCCTGCCAGGGACAGGGGGGTCAAGGAGCAGAGGTGGGACAACTGCAGGGAGCCTTAGGGG
GGAGCAGGCCAGGATGGGTGACCCACTCAGCTCTCAGCCCATCCTGTCCCCTCCCCACAGTGAC
CAACTGCAGCGCCATTGAGGGCGCCGAATACAGCCCCTGTGGCCCTCCCTGTCCTCGCTCCTGT
GACGACCTCGTGCACTGTGTTTGGCACTGCCAGCCCGGCTGTTACTGTCCCCGGGGCCAGGTGC
TGAGTGCTGATGGCGCTGTCTGCGTGCAGCCCAGCCACTGCGGCTGCCTGGACCTGCTGACAGG
TGCACGGCACCATCCGGGCACCCAGCTGGCGAGGCCCGATGGCTGTAACTACTGCACTTGCTCG
GAGGGCAGGCTCACCTGCACAGATCTGCCATGCCCAGTGCCCGGCAGCTGGTGCCCATGGTCGG
AGTGGACCATGTGCACCCAGCCCTGCCGGGGCCAGATGAGGACACGCTCCAGGGCCTGCACCTG
CCCGGCTCCTCAGCATGGGGGGTCTCCGTGCCCTGGCGAGGCGGGGAAGGCAGGGGTCCAGCAT
CAGAGGGAGCCCTGTGCCAGCACCCCTGCGTGCCCAGTGGACGGAGCCTGGAGCCCGTGGGGGC
CGTGGTCTCCCTGTGACGTGTGCCTGGGGCAGTCCCATCGGAGCCGAGCTTGTAACTGGCCTCC
CACCCCAGAGGGAGGCCGGCCCTGCCCTGGGAGCTACAGGCAGAGTCGCCTCTGCTGGGACAAT
TCTACCCAATGCACTGACTGTGCCGGTGGCCAGGCTCTTCTTCCCTGTGGGCAGCCCTGCCCCC
GCTCCTGCCAGGACCTGTCCTCTGGGGTCATGTGTCAGCCAGGCCTGACGGGCTGCCAGCCCAG
CTGTGGGTGCCCCCCCGGCCAGCTGTTCCAGGATGGTCATTGTGTGTCCCCAGCCCAGTGCCGC
TGCCAGTACCAGCCCAGAGCCGTGGGGATCCCTGAGAACCACAGCCGGTCTGCAGGGTCTGGGC
TCAGCTCCTGGGAGAGCCTGGAACCTGGGGAGGTGGTGACTGGGCCGTGTGACAACTGCACCTG
TGTGGCTGGCATCCTGCAGTGCCAGGAGGTGCCTGACTGCCCCGGCCCTGGGGTCTGGGGCTCC
TGGGGTTCCTGGGAGGACTGCAGTGTTTCGTGTGGGGGAGGGGAGCAGCTGCGCTCCCGCCACT
GTGGGCGGCCGCCCTGCCCGGGGCCTGCCCGCCAGAGCCGCTCCTGCCACACCCAGGTCTGCAG
AGAGGCAGGCTGCCCGGCCGGGCGTCTGTACCGGGAGTGCCAGGCTGGCGAGGGGTGCCCCTTC
TCCTGTGCCCACGTCACTCAGCAGGTGGGCTGCTTCTCCGCTGGCTGCGAGGAGGGCTGTCACT
GCCCCGAGGGCACCTTCCTGCACCGCTGGGCCTGTGTCCAGGAGTGCCCCTGCGTGCTGCCTGC
CTCGCTGCCGTGGGAGCTGGGAGCTGCCAGTGCAGACCCTGGGGCTCCCCCCCCGATTCTGGGA
GAGGGAGGTGAGCCCCTCGGGCCTGGAGATGAGCTGGGCTCCGGTCAGACCCTCCGTATAGGCT
GCAGCAACTGCTCCTGCACGCATGGAAAGCTGTCCTGTTCCATGGGGGACTGCGACAAAGCTGG
TGGTGGCTTTGGTCCCTGGGGCCCCTGGGGCCTGTGCTCTCGCTCCTGTGGCGGGCTGGGCACC
CGCACTCGCAGCCGACAGTGTGTGCGTCCTGCACCTGCTCCTGGCGGCCAGAGCTGCCACGGGC
CTCGCCAGGACCTGGAGTACTGCCCCAGTCCTGACTGCCCAGGGGCTACAGGGTCCACGGCGGA
GCCGATGACAGACCTTCCAGGCGACTGGGGCCTGTGGTCCCCGTGGTCCCCCTGCTCCAGCACC
TGCACTGACCCCGCCCATCCTGCTTGGCGCAGCCGCAGCCGCCTCTGCCTGGCAAACTGCACTG
GGGGAGTCACTTCCCAGTGGCGCCCCTGCAACCTGCCCTTCTGCACAGAGCTGCCCCTGTGCCC
TGGCCCTGCCTGCGTGGCCGGGAACTGTTCCTGGACCACTTGGGCCCCATGGGAGCCGTGCTCC
CGCAGCTGTGGAGTGGGCCAGCAGCGTCGCCTGCGGGCGTACCACCCCCCTGGGCCCGGTGGCC
GCTGGTGCCCGGACATCCTCACAGCTTACCAGGAGCGCCGCTTCTGCAACCTGCGTGCTTGCCC
AGTGCCTGGAGGCTGGTCACGCTGGAGCCCCTGGTCCTGGTGTGACCGGAGCTGCGGAGGGGGC
CAATCCTTGAGGAGCCGCAGCTGCTCGAGCCCCCCACCCAAGAACGGGGGTGCCCCCTGTGTGG
GGGAGAGGCACCATGCTCGGCTCTGCAATCCCATGCCCTGTGGGGAGGGCTGCCCAGCAGGCAT
GGAGGTGGTCAGCTGTGCCAACCGCTGCCCGCGCCGCTGCTCAGACCTCCAGGAGGGGATTGTA
TGTCAGGATGACCAGGCCTGCCAGCGGGGCTGCCGCTGTCTCCAGGGCTCCCTGGAGCAGGACG
GCGGCTGCGTGCCCATTGGGCACTGCGAGTGCACTGATGCACAGGGCCAGAGCTGGGCTCCTGG
GAGCCAGCACCAGGAGGCCTGCAACAACTGCACGTGCCGGGCCGGGAGGCTCTCCTGCACGGCT
CAGCCCTGCCCGCCACCCGCCCATTGTGCCTGGAGCCGCTGGTCAGCCTGGAGTCCCTGCAGCC
ACTCATGCGGGCCCTCAGGGCAGCAGAGCCGCTTCCGGTCTTCCACATCGGGCTCCTGGGCCCC
AGAGTGTCGGGAGGAGCAGTCCCAGAGCCAGCCCTGCCCTCAGCCCCCGTGCCCACCCCTGTGC
CTGCACGGGGCCCGCCTGCGCCCCCTGGGGGACAGCTGGCGACAGGGCGAGTGCCAGCAGTGCT
CCTGCACCCCGGAGGGCATCGTATGTGAAGACGTCGAGTGTGCAGGGCCCGGGGCCTGGACGCC
ATGGTCCCCCTGGTCTGGCTGCCCTGTCTCCTGTGGAGGCGGAAACCAGGTCCGCACCCGGGTC
TGCATGGCTTTGGCTGCCCACCAAGAGGGACCCCGGTGCCTGGGCCCGGACACCCAGACCCAGC
GCTGTGGGCAGCAGCCTTGCTGGGGGCTGCTGGACGCCTGCTCCTGGGGCCCCTGGGGGTCCTG
CTCCCGCAGCTGTGGCCCAGGCCTGGCCTCCCGCTCTGGGTCCTGTCCCTGCCCCCCGGCTGAG
GCTGCTGCCACCTGCAATGGTACCTTCCTCCACCTGGACACCCAGGCCTGCTACCCAGGGCCCT
GCCTGGAGGAGTGTGTGTGGAGCAGCTGGAGCAGCTGGACGCGATGCTCATGCCAGGTGCTGGT
CCAGCAGCGCTACCGACACCAGAGGCCAGCACGCAGAGGAGCCGGGGAGGGTCCCCCCTGCACA
CAGCTGGATGGCCACTTCCGGCCCTGCCTCATCGTCAACTGCTCTGAGGACGGCTGCACACCAC
CCTTCGAGTTCCAGGCCTGCGGCTCCCCCTGTGCCAGCCTCTGTGCCACACACCTGAGCCGTCG
GCTCTGCCAGGACCTGCCACCCTGCCAGCCTGGTTGCTACTGCCCCCAGGGACTGCTGGAGCAG
GCTGGAGGCTGCATTACCCCAGAACAGTGTAATTGCCAGCATGGCTCAGGAGAAGGAGCTGGAG
TGACTCTGGCCCCCGGGGACCGCCTGCAGCTGGGCTGCAAAGAGTGTGAATGCCGGCGTGGGGA
GCTGCAGTGCACCAGCCGGGGCTGTCAAGGTCTTCTGCCTCTGAGCGGCTGGTCTGAGTGGTCA
CCCTGTGGGCCCTGCCTGCCCCCCAGCCTGCTGGCCGCTGCCTCCAGGACTGCCCTGGAGGAGC
ACTGGCCCTGGGATCCAGCTGGCCTCTCCCCAACCCCGGCCTCCATGCTGGCTTCGGAGCAGCA
CCGCCACCGCCTCTGTTTGGACCCTGAGACAGGGAGGCCGTGGGCCGGGGACCCAGACCTCTGC
ACTGTGCCACTCAGCCAGCAACGCCTCTGTCCAGACCCTGGAGCCTGCCAAGACTCATGCCAGT
GGAGTCCTTGGGGGCCCTGGAGCCGCTGCCAGGTGCCCTGCAGTGGGGGGTTCCGGCTGCGCTG
GAGAGAGGCCGGGGGCCCCCCCGGAGGAGGCTGCCAGGGCCCATGGGCGCAGACCGAGAGCTGC
AACATGGGGCCTTGCCCAGGAGAGAGCTGCGAGGCTCGGGACACCATGCCCACCCCTGACTGTG
CCAACCAGTGCCCAAGAAGCTGTGCCGATCTCTGGGACCGTGTGCAGTGTCTGCAGGGACCGTG
CCGCCCAGGCTGCCGCTGTCCCCCTGGCCAGTTGGTGCAGGATGGGCACTGTGTGCCAGTGACC
TCTTGCCGCTGTGGTCTTCCCAGCCACAATGCTTCCTGGGTGCTGGCCCCGGCTGAGGTGGTAC
AGCTGGACTGCAAAAACTGCACCTGTGTCAACGGGTCCCTGGTGTGTCACCCCCATGAATGTCC
AGCCCTTGGGCCTTGGTCCGCCTGGAGCCGCTGCTCTGCTCCCTGCGGTGGGGGCACTGCCAAG
CGACAGCGGAGCTGCAAGGAGGGCCCTGGGGGGGCACCGTGCGAGGCCCAGGACACAGAGCAAT
GGCAGGAGTGTAACCTGCAGTCCTGCCCCGAGTGCCCTCCCGGCCAGGTGCTCAGTGCCTGTGC
TACCTTGTGCCCGCGCCTCTGCTCGCATCTGCAGCCGGGCACCCTCTGCGTGCAGGAACCCTGC
CAGCTTGGCTGCGGCTGCCCAGGAGGGAAGCTGCTGCACAATGGCACGTGTGTGCCCCCTGCCG
CGTGCCCCTGCGCCCAGCTCTCTCTGCCCTGGGGCCACACTTTGACTCTCGAAGAGCAGGCCCA
GGAGCTGCCCCCAGGAACTCTGCTCACCCAGAACTGCACCCACTGTGTCTGCCAGGGTGGAGCC
TTCAACTGCTCCCGCGGTGACTGTCATGAGTGCCCCCCTGGAGAAATGTGGCAGCAGGCGGCCC
CTGGGGAACTGGGGCCCTGTGAGCAGACGTGTCGGGAGCTCAACGCCGTGGAGGCTTGGGGCAA
CTGCAGTGCGGGGCAGGCTGCAGGCTGTGTGTGCCCGCCTGGGCGCTTCCGCAGCCAGCAGGGC
CTCTGCGTGCCCGCAGGCCAGTGCGAGTGCTGGCGCCACGGGCGTCCCCACCCGCCCGGATCCA
AGTGGCAGGAGGCCTGTGAGAGCTGCCGCTGCGTTGGTGGGAGGAGTGTCTGCACCCAGCCCTG
CCCCATCCTCTCCTGTGCCCAGGGTGAGGAGGCCGTGCAGGAGCCAGGCAGCTGCTGTCCCACT
TGCCGCCAGGAGACTCCAGAGGAGCGGCCTGCCTCCTGCCGGCACCTCACTGAGCTTCGCAACA
TCACCAAGGGCCCCTGTTACCTGGACCAGGTGGAAGTGAGCTACTGCAGTGGGCAGTGCCCATC
CAGCACCAACGTCCTGCCAGAGGAGCCGTACCTGCAGAGCCAGTGCGACTGCTGTAGCTACCGC
CTGGACCCCGAGAACCCGGTGCGGATCCTGAACCTGCGCTGCCCCGGCGGCCACACAGAGCTGG
CGGTGCTGCCGGTCATCCACAGCTGCCAGTGCAGCGCGTGCCAGGGAGGTGATTTCTCAAAGCG
CTGACGGCTCCGCTGGGAGAAGCCCCGCCGCCTCTCTTGGGGTCCCTGGGCTCAGCAGCACGAA
CCCCTCCTCCTCTCATGCCCACCCATCCCCTCCCCGTCCTGGCTGTGGTGTATCCCAAATAAAG
CGACCTTGGCAGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_084861143	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000076781.1
	ENSSSCP00000079217.1

RefSeq Acc Id:

XP_020934406 ⟸ XM_021078747

- Sequence:

show sequence

MAGVAVVPGSPPPHRRWCKRTETIWVEEEVTPRQEDLVPCTSLSHYQRRGWRLDLTWSGHEGLC
PIYKPPETRPAAWNRTVRVCCPGWGGPHCTLALAETSPEGHCFATGLCQLRAGSANASAGSLEE
CCAQPWGQSWQDGRSQACLSCSSHQLPGTVPSPALLQPLAGAVAQLWSQRQRPSATCATWSGFH
YRTFDRRHYHFLGRCTYLLAGAADSTWAVHLEPRGHCPQPGHCQLARVMMGPEEVLVRGRNVSV
NGQLLPDGESQLLPGLSLQWQGDWLVLSGGLGVVVRLDGSSSVSISVDHELQGQTQGLCGVYNG
QPEDDFLEPGRRLAGLAATFGNSWRLPDSEPGCLDAVEAAQGCEDPLRGTEAGMEPGQLQAEAQ
DVCHQLLDSPFRDCHVQVPPAEYHEACLFAYCAAAPAGSGREERLEAICATLANYAQDCAARRV
LLRWRKPGFCERQCPGGQLYSDCASACPPSCSAVDDGGEGSCGEECVSGCECPPGLFWDGAVCV
PAARCPCYHRRRRYNPGDTVRQLCNPCVCQDGRWLCAQAPCPAECAVGGDGHYLTFDGRSFFFR
GGPGCGSRLVQDFVKRELLIVLEHGDCDSGNCLRAISVTLGDTHVQLRDSGAVLVDGQDVGLPW
SGAGGLSITRASSTFLLLRWPGAHVLWGTSDPAAYITLDPRHAHQVQGLCGTFTWNQQDDFLTP
TGDVETSVAAFASKFQVAGEGRCPSEEDSTSLSPCSTHAQSRVFAEAACAILHGPAFQECHGLV
DREPFHLRCLAAVCSCAPGRDCLCPVLAAYARRCAQEGALPSWRNQSLCPVLCPGGQEYQECAP
ACGQNCGEPEDCGELGTCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGDHRYAPGSAVRKDCNHC
VCRERGLWNCTAHHCAPERAFCPGELVYVPGACLLTCDNPHANGSCPPGSMGGCVCPPGNVLLD
ERCVHPELCPCRHGGQWYPPNATIQEDCNMCVCQGRQWHCTGQRCDGRCQASGAPHYVTFDGLA
FTFPGACEYLLLREADGQFTVSAQNLPCGASGLTCTKALTVRLQSAVVHMLRGQAVTVNGVSVT
PPKVYTGPGLSLHRAGLFLLLTTRLGLTLLWDGGTRVLVQLSPQFHGRVAGLCGDFDGDASNDL
RSRQGVLEPTAELAAHSWRLNPLCPEPGDLPYPCTVNAHRAGWARARCGVLLQPLFAQCHAEVP
PQRHYEWCVYDTCGCDAGGDCECLCSAIATYADECARHGLHVRWRSQELCRECARPLVPGIQSL
HSLSSLKDTSPGLRAIHSLKGRYTWNVPCARHLPMDQTCPNPCSVELACCTQPWEGPSKRPHAP
PCPPQVSPSVGSPAAVASWCPGSDPSLSPLHPALQCEGGQVYEACGPTCPPTCHDRGLEPGWHC
QAVACVEGCFCPEGTLLHGGVCLEPASCPCEWGGSFFPPGTVLQKDCGNCTCQESQWLCGEDGS
HCEELVPGCAEGEVPCQESGHCVPHSWLCDNQDDCGDGSDEAGCATPGCGEGQMSCSSGHCLPL
ALLCDGRDDCEDGMDEQGCPCPPDSLPCADGRCLPLALLCDGHPDCPDAADEESCLGQVSCTPG
EVSCVDGACVGALRLCDGIWDCPNGADEGPGHCPLPSLPMPPAGTLPGLSTASQGTPPTPPARV
SPAPPCGPLDIACGSGECAPRGWRCDGEEDCADGSDEHGCGWPCAPPHAPCARGPLCVAPAQLC
DGVPHCPDGWDESPGACEGLPAPGGPNGTGVPCSEYSCPDGLCIGFQQVCNGQPDCELAGEVGS
SPEEQGCGAWGPWSPWGPCSQTCGPGVQARSRRCSPPSLPVLQHCLGPEHQTQACFTAACPVDA
EWTSWSPWSPCSEPCRGTRTRQRQCHPPQNGGRTCAMLPGDPHGTHQTGPCPQDGCPNVTCSRE
LVFHPCAPCPLTCDDISGQAVCPPDPPCSSPGCWCPTGQVLDDKGRCVWPGQCPCLVDGIHYPP
GQRIKADCQLCICQDGRPRRCRPNLDCAVNCGWSLWSPWAECLGPCGSLSIQWSFRSPNNPRLS
GRGHQCRGIHRKARRCQTRPCGGCEQHGQVHRVGERWRGGPCKVCQCLHNGTAHCSPYCPLGSC
PQDWVLVEGVGESCCHCAPPGVNWTVQPMATPGPTPAPSPQIGPSLITYVLPPPGDSCYSRLDL
TRLPKGSLQASPQLLDQPTGEPGQQTWSPAEAGDLLRHMQAPYLQLDLLRPRNLTGIMVQGAGS
SDLLQFSSDGLHWHSYRDLLPAIQPPLKLFPGTRDDVAPTVWLFGRMVQARHVRVWSLDVTRGP
ESDVNHSIPLQVELLGCEPAPACPGAGHRCASGSCVLRGTLCDGVEDCEDGSDEEGCVPPPTGT
ARVQSTARTPALYHTQPGWLHPQPMEGLAETERWHPRQGSPPPPTGKWPASLVSASPPSPEDFV
QTAPATPTSRPEVTTPRPEMAAVTVLPPHPTMSVARDGHSIAPAPFPPMRCRLGQVPCKVLGCM
EQEQLCDGKEDCLDGSDERSCGLSLSFSWNHVCDPVPPPPPAAWAGGTVPFTVPTTALPGLPAS
RALCSPSQLSCGSGECLPAERRCDLQPDCQDGSDEDGCVDCGLAPWSGWSSCSHSCGLGLAFQR
RELQRPPLPGGSCPPDRLRSRSCFVRACPVAGAWAEWEAWGPCSVSCGGGHRSRRRSCVDPPPK
NGGAPCPGASQEGAPCGLQSCTGGTDCGLGRVHVSEEMCQKGLVPPCPPSCLDPEANRSCSGHC
LEGCRCPPGLLLQDTRCLPLSECPCLVGEELQQPGQPFLLDNCSRCMCQKGALLCEPGGCPMPC
GWSAWSSWGPCDRSCGSGLRARFRSPSNPPAASGGAPCEGERQELQACHLSTCGAEPLGWTPWT
PWSTCSQSCLVPGGGPGWRSRSRLCPSPSNMSCPGEAIQEEPCSPLVCPVASIWGLWAAWSTCS
APCDGGIQTRGRSCPALAPGNPGCHGPHSQTRDCNMQPCTAQCPEDMVFRSAEQCRQEGGPCPR
LCLAQGPGVECSGLCSPGCTCPPGLFLHNASCLPLSQCPCQLRGQLYAPGAVARLDSCNNCTCI
SAEMVCTSEPCPVACGWSPWTPWSLCSRSCDVGIRRRFRAGTAPPAAFGGPSCQGPNVEAEFCS
LQPCQGPGEEWGPWSPCSVPCGGGYRNRTRGGSGHSPVDFSTCSLQPCAGPVPGVCPPGKRWLD
CAQGPASCAELSTPRGTDQPCHAGCYCLPGMLLLNNVCVPTQDCPCTHGGRLHPPGSAVLRPCE
NCSCVSGLVTNCTAWPCEEARPTWSPWTPWSECSASCGPAHRHRHRFCPRPPSVAQPPPSASPP
LPCPGLEADEEPCLLPACDRAGAWGPWGPWSSCSRSCGGGLWSRTRACDQPPPQGLGDYCEGPR
AQGAACQVLPCPGACQGQGGQGAEVGQLQGALGGSRPGWVTHSALSPSCPLPTVTNCSAIEGAE
YSPCGPPCPRSCDDLVHCVWHCQPGCYCPRGQVLSADGAVCVQPSHCGCLDLLTGARHHPGTQL
ARPDGCNYCTCSEGRLTCTDLPCPVPGSWCPWSEWTMCTQPCRGQMRTRSRACTCPAPQHGGSP
CPGEAGKAGVQHQREPCASTPACPVDGAWSPWGPWSPCDVCLGQSHRSRACNWPPTPEGGRPCP
GSYRQSRLCWDNSTQCTDCAGGQALLPCGQPCPRSCQDLSSGVMCQPGLTGCQPSCGCPPGQLF
QDGHCVSPAQCRCQYQPRAVGIPENHSRSAGSGLSSWESLEPGEVVTGPCDNCTCVAGILQCQE
VPDCPGPGVWGSWGSWEDCSVSCGGGEQLRSRHCGRPPCPGPARQSRSCHTQVCREAGCPAGRL
YRECQAGEGCPFSCAHVTQQVGCFSAGCEEGCHCPEGTFLHRWACVQECPCVLPASLPWELGAA
SADPGAPPPILGEGGEPLGPGDELGSGQTLRIGCSNCSCTHGKLSCSMGDCDKAGGGFGPWGPW
GLCSRSCGGLGTRTRSRQCVRPAPAPGGQSCHGPRQDLEYCPSPDCPGATGSTAEPMTDLPGDW
GLWSPWSPCSSTCTDPAHPAWRSRSRLCLANCTGGVTSQWRPCNLPFCTELPLCPGPACVAGNC
SWTTWAPWEPCSRSCGVGQQRRLRAYHPPGPGGRWCPDILTAYQERRFCNLRACPVPGGWSRWS
PWSWCDRSCGGGQSLRSRSCSSPPPKNGGAPCVGERHHARLCNPMPCGEGCPAGMEVVSCANRC
PRRCSDLQEGIVCQDDQACQRGCRCLQGSLEQDGGCVPIGHCECTDAQGQSWAPGSQHQEACNN
CTCRAGRLSCTAQPCPPPAHCAWSRWSAWSPCSHSCGPSGQQSRFRSSTSGSWAPECREEQSQS
QPCPQPPCPPLCLHGARLRPLGDSWRQGECQQCSCTPEGIVCEDVECAGPGAWTPWSPWSGCPV
SCGGGNQVRTRVCMALAAHQEGPRCLGPDTQTQRCGQQPCWGLLDACSWGPWGSCSRSCGPGLA
SRSGSCPCPPAEAAATCNGTFLHLDTQACYPGPCLEECVWSSWSSWTRCSCQVLVQQRYRHQRP
ARRGAGEGPPCTQLDGHFRPCLIVNCSEDGCTPPFEFQACGSPCASLCATHLSRRLCQDLPPCQ
PGCYCPQGLLEQAGGCITPEQCNCQHGSGEGAGVTLAPGDRLQLGCKECECRRGELQCTSRGCQ
GLLPLSGWSEWSPCGPCLPPSLLAAASRTALEEHWPWDPAGLSPTPASMLASEQHRHRLCLDPE
TGRPWAGDPDLCTVPLSQQRLCPDPGACQDSCQWSPWGPWSRCQVPCSGGFRLRWREAGGPPGG
GCQGPWAQTESCNMGPCPGESCEARDTMPTPDCANQCPRSCADLWDRVQCLQGPCRPGCRCPPG
QLVQDGHCVPVTSCRCGLPSHNASWVLAPAEVVQLDCKNCTCVNGSLVCHPHECPALGPWSAWS
RCSAPCGGGTAKRQRSCKEGPGGAPCEAQDTEQWQECNLQSCPECPPGQVLSACATLCPRLCSH
LQPGTLCVQEPCQLGCGCPGGKLLHNGTCVPPAACPCAQLSLPWGHTLTLEEQAQELPPGTLLT
QNCTHCVCQGGAFNCSRGDCHECPPGEMWQQAAPGELGPCEQTCRELNAVEAWGNCSAGQAAGC
VCPPGRFRSQQGLCVPAGQCECWRHGRPHPPGSKWQEACESCRCVGGRSVCTQPCPILSCAQGE
EAVQEPGSCCPTCRQETPEERPASCRHLTELRNITKGPCYLDQVEVSYCSGQCPSSTNVLPEEP
YLQSQCDCCSYRLDPENPVRILNLRCPGGHTELAVLPVIHSCQCSACQGGDFSKR

hide sequence

Protein Domains

CTCK F5/8 type C VWFC VWFD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000039661	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000045656.3	UniProtKB/TrEMBL
	ENSSSCT00000095078.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.128.620	UniProtKB/TrEMBL
	Galactose-binding domain-like	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
	Low-density Lipoprotein Receptor	UniProtKB/TrEMBL
	Thrombospondin type-1 (TSP1) repeat	UniProtKB/TrEMBL
InterPro	Cys_knot_C	UniProtKB/TrEMBL
	FA58C	UniProtKB/TrEMBL
	Galactose-bd-like_sf	UniProtKB/TrEMBL
	LDL_receptor-like_sf	UniProtKB/TrEMBL
	LDLR_class-A_CS	UniProtKB/TrEMBL
	LDrepeatLR_classA_rpt	UniProtKB/TrEMBL
	Mucin_vWF_Thrombospondin_sf	UniProtKB/TrEMBL
	Pacifastin_dom_sf	UniProtKB/TrEMBL
	Ser_inhib-like_sf	UniProtKB/TrEMBL
	TIL_dom	UniProtKB/TrEMBL
	TSP1_rpt	UniProtKB/TrEMBL
	TSP1_rpt_sf	UniProtKB/TrEMBL
	VWF/SSPO/ZAN-like_Cys-rich_dom	UniProtKB/TrEMBL
	VWF_dom	UniProtKB/TrEMBL
	VWF_type-D	UniProtKB/TrEMBL
NCBI Gene	SSPO	ENTREZGENE
PANTHER	EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED	UniProtKB/TrEMBL
	SCO-SPONDIN	UniProtKB/TrEMBL
Pfam	F5_F8_type_C	UniProtKB/TrEMBL
	Ldl_recept_a	UniProtKB/TrEMBL
	PF08742	UniProtKB/TrEMBL
	TIL	UniProtKB/TrEMBL
	TSP_1	UniProtKB/TrEMBL
	VWD	UniProtKB/TrEMBL
	VWF	UniProtKB/TrEMBL
PRINTS	LDLRECEPTOR	UniProtKB/TrEMBL
PROSITE	CTCK_2	UniProtKB/TrEMBL
	FA58C_3	UniProtKB/TrEMBL
	LDLRA_1	UniProtKB/TrEMBL
	LDLRA_2	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
	VWFC_1	UniProtKB/TrEMBL
	VWFC_2	UniProtKB/TrEMBL
	VWFD	UniProtKB/TrEMBL
SMART	LDLa	UniProtKB/TrEMBL
	SM00041	UniProtKB/TrEMBL
	SM00832	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
	VWC	UniProtKB/TrEMBL
	VWC_out	UniProtKB/TrEMBL
	VWD	UniProtKB/TrEMBL
Superfamily-SCOP	FnI-like domain	UniProtKB/TrEMBL
	Galactose-binding domain-like	UniProtKB/TrEMBL
	LDL receptor-like module	UniProtKB/TrEMBL
	PMP inhibitors	UniProtKB/TrEMBL
	Serine protease inhibitors	UniProtKB/TrEMBL
	TSP-1 type 1 repeat	UniProtKB/TrEMBL
UniProt	A0A8W4FBK8_PIG	UniProtKB/TrEMBL
	A0A8W4FLN3_PIG	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-06-13	SSPO	SCO-spondin	SSPOP	SCO-spondin	Symbol and/or name change	5135510	APPROVED
2022-08-09	SSPOP	SCO-spondin	SSPO	SCO-spondin	Symbol and/or name change	5135510	APPROVED
2020-08-04	SSPO	SCO-spondin	SSPOP	SCO-spondin, pseudogene	Symbol and/or name change	5135510	APPROVED
2020-01-21	SSPOP	SCO-spondin, pseudogene	SSPO	SCO-spondin	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - PID (archival)