Advanced Search (OLGA)

Gene: SPTLC2 (serine palmitoyltransferase long chain base subunit 2) Sus scrofa

Subscribe to Updates

Analyze

Symbol:

SPTLC2

Name:

serine palmitoyltransferase long chain base subunit 2

RGD ID:

14117549

Description:

ENCODES a protein that exhibits acyltransferase activity (inferred); pyridoxal phosphate binding (inferred); serine C-palmitoyltransferase activity (inferred); INVOLVED IN response to immobilization stress (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); serine palmitoyltransferase complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine palmitoyltransferase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	100,544,478 - 100,638,905 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	100,545,360 - 100,638,973 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	106,672,604 - 106,730,716 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	COVID-19		ISO	SPTLC2 (Homo sapiens)	9068941	mRNA:increased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	Charcot-Marie-Tooth disease		ISO	SPTLC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Charcot-Marie-Tooth disease	ClinVar	PMID:17081983 more ...
SPTLC2	Pig	genetic disease		ISO	SPTLC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:17576681 more ...
SPTLC2	Pig	hereditary sensory and autonomic neuropathy type 1C		ISO	SPTLC2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:16199547 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	psoriasis		ISO	Sptlc2 (Mus musculus)	9068941	OMIM:177900 more ...	MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	hereditary sensory and autonomic neuropathy type 1C		ISO	SPTLC2 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	adipose tissue development	involved_in	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	biosynthetic process	involved_in	IEA	InterPro:IPR004839	150520179		InterPro	GO_REF:0000002
SPTLC2	Pig	ceramide biosynthetic process	involved_in	IBA	MGI:108074 more ...	150520179		GO_Central	GO_REF:0000033
SPTLC2	Pig	ceramide biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:O15270 more ...	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	positive regulation of lipophagy	acts_upstream_of_or_within	IEA	UniProtKB:O15270 and ensembl:ENSP00000216484	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	response to immobilization stress		ISO	Sptlc2 (Rattus norvegicus)	9068941		RGD	PMID:34449011 and REF_RGD_ID:213230152
SPTLC2	Pig	sphinganine biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	sphingolipid biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:O15270 and ensembl:ENSP00000216484	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	sphingolipid biosynthetic process	involved_in	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	sphingomyelin biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	sphingosine biosynthetic process	involved_in	IBA	MGI:108074 more ...	150520179		GO_Central	GO_REF:0000033
SPTLC2	Pig	sphingosine biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	sphingosine biosynthetic process	involved_in	IEA	UniProtKB:O15270 and ensembl:ENSP00000216484	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	membrane	located_in	IEA	GO:0006686 more ...	150520179		GOC	GO_REF:0000108
SPTLC2	Pig	serine palmitoyltransferase complex	part_of	IBA	PANTHER:PTN000343811 more ...	150520179		GO_Central	GO_REF:0000033
SPTLC2	Pig	serine palmitoyltransferase complex	part_of	IEA	UniProtKB:O15270 and ensembl:ENSP00000216484	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	acyltransferase activity	enables	IEA	UniProtKB-KW:KW-0012	150520179		UniProt	GO_REF:0000043
SPTLC2	Pig	protein binding	enables	ISO	UniProtKB:O15269	9068941	PMID:19416851 and PMID:35271311	IntAct	PMID:19416851 and PMID:35271311
SPTLC2	Pig	pyridoxal phosphate binding	enables	IEA	InterPro:IPR004839	150520179		InterPro	GO_REF:0000002
SPTLC2	Pig	serine C-palmitoyltransferase activity	enables	IBA	FB:FBgn0002524 more ...	150520179		GO_Central	GO_REF:0000033
SPTLC2	Pig	serine C-palmitoyltransferase activity	contributes_to	IEA	UniProtKB:P97363 and ensembl:ENSMUSP00000021424	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	serine C-palmitoyltransferase activity	enables	IEA	UniProtKB:O15270 and ensembl:ENSP00000216484	150520179		Ensembl	GO_REF:0000107
SPTLC2	Pig	transferase activity	enables	IEA	InterPro:IPR001917	150520179		InterPro	GO_REF:0000002

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
SPTLC2	Pig	Fabry disease pathway		ISO	SPTLC2 (Homo sapiens)	9068941		SMPDB	SMP:00525
SPTLC2	Pig	Gaucher's disease pathway		ISO	SPTLC2 (Homo sapiens)	9068941		SMPDB	SMP:00349
SPTLC2	Pig	Krabbe disease pathway		ISO	SPTLC2 (Homo sapiens)	9068941		SMPDB	SMP:00348
SPTLC2	Pig	metachromatic leukodystrophy pathway		ISO	SPTLC2 (Homo sapiens)	9068941		SMPDB	SMP:00347
SPTLC2	Pig	sphingolipid metabolic pathway		ISO	SPTLC2 (Homo sapiens)	9068941		SMPDB	SMP:00034

PMID:14681463	PMID:22301074	PMID:30032202

SPTLC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	100,544,478 - 100,638,905 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	100,545,360 - 100,638,973 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	106,672,604 - 106,730,716 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPTLC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	77,505,997 - 77,616,637 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	77,505,997 - 77,616,637 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	77,972,340 - 78,082,980 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	77,043,023 - 77,152,863 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	77,043,024 - 77,152,863	NCBI
Celera	14	58,011,851 - 58,121,636 (-)	NCBI		Celera
Cytogenetic Map	14	q24.3	NCBI
HuRef	14	58,138,337 - 58,249,054 (-)	NCBI		HuRef
CHM1_1	14	77,911,814 - 78,022,586 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	71,715,382 - 71,825,999 (-)	NCBI		T2T-CHM13v2.0

Sptlc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	87,351,832 - 87,435,129 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	87,351,832 - 87,435,129 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	87,305,058 - 87,388,355 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	87,305,058 - 87,388,355 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	88,648,839 - 88,729,180 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	88,196,992 - 88,277,333 (-)	NCBI		MGSCv36	mm8
Celera	12	88,772,417 - 88,852,773 (-)	NCBI		Celera
Cytogenetic Map	12	D2	NCBI
cM Map	12	41.52	NCBI

Sptlc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	112,679,623 - 112,762,470 (-)	NCBI		GRCr8
mRatBN7.2	6	106,948,682 - 107,031,532 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	106,950,949 - 107,031,542 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	107,116,961 - 107,199,840 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	107,415,779 - 107,498,659 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	106,785,468 - 106,868,346 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	111,334,408 - 111,417,960 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	111,339,136 - 111,417,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	120,616,251 - 120,699,243 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	111,546,037 - 111,622,959 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	111,245,978 - 111,626,585 (-)	NCBI
Celera	6	104,771,427 - 104,849,755 (-)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

Sptlc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	1,385,431 - 1,491,578 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	1,385,431 - 1,491,534 (-)	NCBI	ChiLan1.0	ChiLan1.0

SPTLC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	78,591,247 - 78,702,589 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	77,807,751 - 77,918,929 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	58,066,123 - 58,170,472 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	77,266,545 - 77,370,663 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	77,266,545 - 77,370,663 (-)	Ensembl	panpan1.1		panPan2

SPTLC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	50,291,797 - 50,401,202 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	50,271,010 - 50,401,313 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	49,979,477 - 50,088,850 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	50,525,698 - 50,635,391 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	50,530,838 - 50,635,427 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	50,188,135 - 50,297,514 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	50,211,301 - 50,320,641 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	50,609,185 - 50,719,362 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101967158
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	25,664,744 - 25,778,794 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	6,315,715 - 6,419,882 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936488	6,289,833 - 6,296,849 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	6,313,189 - 6,404,425 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPTLC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	54,769,072 - 54,876,963 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	42,955,305 - 43,064,586 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sptlc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624734	24,281,482 - 24,400,870 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in SPTLC2
3326 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3


RefSeq Transcripts	XM_021099554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK230782	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU468695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU607058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01041499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000064054 ⟹ ENSSSCP00000045377

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	100,544,478 - 100,638,905 (-)	Ensembl

RefSeq Acc Id:

XM_021099554 ⟹ XP_020955213

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	100,545,360 - 100,638,973 (-)	NCBI

Sequence:

show sequence

TTTCCGGTTTCGGGGTGGTGGGAGGGGTGCGGAGCGGGACTTGGAGCCGCCGCTGCTTTGCCCGCCGCGTACAGATCCTGCCTCGCGCTTGGTGCTGCTGGGATGATGCGGTCGGGTCCCGAAGGCTG
CTGCCGTCGCCCGGTGCGGGCGAACGGCTGCGTGGCGAACGGGGAGGTGCGGAACGGGTACGTGAGGAGCAGCGCCGCTGCCGCCGCAGCCGCTGCCGGCCAGATACATCATGTTACACAAAATGGAG
GACTGTATAAAAGACCATTTAACGAAGCTTTTGAAGAAACACCAATGCTGGTCGCTGTGCTTACTTATGTCGGGTATGGTGTACTCACTCTCTTTGGATATCTTCGAGATTTCTTGAGGCATTGGAGA
ATTGAAAAGTGTCACCATGCAACGGAAAGAGAAGAACAACAGGACTTTGTGTCATTGTATCAGGATTTTGAAAACTTCTATACAAGGAACCTCTATATGAGGATTCGAGACAACTGGAATCGACCCAT
CTGCAGTGTGCCTGGAGCCAGGGTGGACATCATGGAGAGACAGTCTCACGACTACAACTGGTCATTCAAGTACACCGGGAATATAATTAAAGATGTTATAAACATGGGTTCCTACAATTATCTTGGAT
TTGCACGAAATACTGGAGCATGTCAAGAGGCAGCTGCCAAAGTCCTGGAGGAGTATGGTGTTGGAGTGTGCAGCACTCGGCAGGAAATTGGAAACCTGGACAAGCATGAAGAACTAGAGAAGCTTGTG
GCAAGTTTCTTGGGAGTAGAAGCTGCTATGGCATATGGCATGGGGTTTGCAACAAATTCAATGAACATTCCTGCTCTTGTTAGCAAAGGTTGCCTAATTCTGAGTGATGAACTAAACCATGCGTCACT
GGTTCTGGGAGCCAGACTCTCAGGAGCAACCATTCGAATCTTCAAACACAACAATATGCAAAGCCTAGAGAAGCTGTTGAAGGATGCCATTGTTTATGGTCAGCCTCGGACACGAAGGCCCTGGAAGA
AAATTCTAATCCTTGTGGAGGGAATATATAGCATGGAGGGATCTATTGTTCGCCTTCCTGAAGTGATTGCCCTTAAGAAGAAATACAAGGCATACTTGTATCTAGATGAAGCTCACAGCATTGGGGCT
CTGGGCCCCACAGGTCGAGGTGTGGTGGACTACTTCGGCCTGGATCCTGAGGACGTGGACATTATGATGGGAACATTTACAAAGAGCTTTGGTGCTTCTGGAGGATACATTGGAGGCAAGAAGGAGCT
GATTGACTATCTGCGGACACATTCTCACAGTGCCGTGTACGCCACGTCGCTGTCGCCACCTGTCGTGGAGCAGATCATCACCTCTATGAAGTGCATCATGGGGCAGGATGGCACCACCCTTGGCAAAG
AATGTATACAGCAGTTAGCCGAAAACACCAGGTATTTCAGGAGACGTCTAAAAGAGATGGGCTTCATCATCTATGGAAATGAAGATTCTCCAGTTGTGCCTCTGATGCTCTACATGCCGGCCAAAATT
GGCGCCTTTGGGCGGGAGATGCTAAAGCGGAATGTCGGTGTCGTTGTGGTAGGATTTCCTGCTACCCCAATCATCGAGTCCAGAGCCAGGTTTTGCCTGTCGGCAGCTCATACCAAAGAAATACTTGA
TACTGCTTTAAAGGAGATAGATGAAGTCGGGGACCTGTTGCAGCTGAAGTATTCCCGTCATCGGTTGGTACCCCTACTGGACAGGCCCTTTGATGAGACTACATATGAAGAAACAGAAGACTGAGCCT
TTTTGGTGCTCCCCTTGAGGGCCTCTCCCGCCCCCAGGACAGCGTGTGGCCTTTCTGAGCCAGTTCCAGGAACCACACTTCTGTGGCCGACTCACGTGCAAGACATTTCCTCAACTACTGACGGTGGC
CACCTCCACTCTAAATGGCATTTTGTAAATAGAAACTGCTTCACATCCTTCCTTTGCTACAGTTCACCGTTTAAAAAAGAGGTGACTCACTTTGCTTTTTTGTGCATTAAAAAGTATGTTTTATTTTT
TAACTACTCCACTTGTGACATCACGCTGACCCTAGCCTGCCTCTGGCTAACCTCGAAGGCCTTTTTCCTCTCCCAGCCACTTCCCAGACATGGGCGCATTGAAAGGTCCTGCTGGCCCTGACTCTGTG
GCCTCAAGACTCCGCTGGCCCTCCTCCCGGGGAGCAGGTGCCTTCCACTTACTTCCAGTCCAGGTCTCAGAGGTTGCCAGTCTTGGAATCTTTCTTTAACCTGCCACATAACCCAAGTGTTTTAATGC
GTCTTAAGTTTATCCATTTGAGAAAAACAGTAAATGCTAATCCTGCTGAAACTCCCCCTCATTGTGTGACCCTCCCTGGCCAGGAGCCTCCAGGGATGGGGCTTAGTCCATTCTCTTCTGGTGACCAG
ATGTTTCTTCGTAATTGTCACCATCTGAGGGCATGTCCAATTTCGGGATTCTTCCCAAGCTATAATCCTACACTCCCACCTCTATTTAAAACACTTAAATTGTTTTAAAAGCACCCACATCCCACCCC
AGTCAGACGTCTGTGGTGAAGCTGACTTGCACCCCACTATTCTGAGTACAAAGCTGCTCGATAGAGTGACTTGTACTTCTCTGGGGTAAGAGGGCAGGGGCCGTGTGGAAGGAATTGATGGCTCCTTA
CAGTGTCTGTGGTTTAGTTCTTATTACTTTCACATTTTCAAAATTGGGACAGCCCCTGCCTGGGTCTGGGTCCAGATTAGGACTTAAACTGATGAAAGAAAATGTTGGTAAATTCTCTGCTCAGAAAT
CATTTATCATGTTCCTAATTTAAGGATTAAACTTTTTAATTTACTCTTTTCAGGAGATGACCCATTTAAATATCACTGTCTGTGTGCTGGTTCTCCTTCATTCTTGATGTTCTCACGCAGTTCTAACC
TGGCATTGGGGGTCTAGAGGCGCCATCTCCTTCCGCTACCACCCCCCCCCTTTTCCCTTGAGAAATCCCGAACGTGTTTTTCTGTGCTAAACTGGGATCCTCTGTTTTGACTTTTCATACCAGGTGAG
GGGACTTCTTTCAGAGAGCTTTATACTGTTCAACCAAAGAACACATCTGAAAGTCACCATTGGAAAAGTTCCCTTTATTGCTTGTTTTCTGTTACGCTTAAGTGAAGAGAACTCTTGACTTTTTTCCT
ACCCAAGATCAGCTTGTCTTTTAATAGCCGTCAAATATCATGGGGGGAGGGATTGGAAACAAAATGGAAAAACATTGTGTGAAAGTTTTTGCACGTCATATTTTTTGAAATTATTCCTTTGATTGGTA
AAAACTCTCAGCCCAGATTCTCCTAAGCATCTCGTCATCAGCTGTGGTATGTTTGTGCAGGTACATGTGGTGGAGGATGTAAGCAATGCTATTATTGTTTGTGAAGTTTTATTTTCATGTCTTTTTTT
GCTTGTTAGGGCCGCATCCATGGCATATGGAAGTTCCCAGGCTAGGGGTCAAAGAATCGGGGCTACAAGCTGCTGGCCTACACCGAGCCTTGTCTGTGACCTGCATCACAGCTCACGGCAAAGCTGGA
TCCTTAACCCGCTCAGTGAAGCCAGGGACTGAACCTGCATCCTCATGGATACTAGTCAGGTTCCTTTCCACTGAGCCATAACCGGAACTCCTGTTTTCATGTCTTAAGTTACCTTTGGTCACTCTCAG
CATCTGAGAGCCTTAAGCCCTTGAAATATTCTAAGGTTTTATTTTACCTTTGTAAAGAGTAGAAAAAGGTGAATAAAAAAAAAAAACCAAGTACAGATGCAGGGACTGTATTTAGCATGTACAAGTTG
AAGTAAAAAAAGATACCACTTGGTGGTAACTAAGTAATTCGTCTTGTAAAATAAAATACATTACTAACCTTTCCCGCATATCTAGGTCCTCACCATAGACACCGTTAGAACACTAGAGAGCTTTTGCA
TTGTAGCTGCTATTTCATGGTAGAGGGTCCATGAAAAGTCATAAACATCAAGCAGTAAACTTACCAGCTAGTCCTTTCTTTTGGCTTGCATGAAGTCACTGTAACTTAAAATGTCAGTTAGTATGGGC
ATTGAAAATATATGTGTGTAAATATATATATATGCACACATGTATGTGTGTGTGTGCATATATATATATATCACTTTGCTTGTGCAGTTAGTTCTGGATAAATGCAGTTAAGTTACAGATTTATTTTG
AAGCGTTAAAACTCCTGTGATCTCTCCAGGACATCTACTTTCTAGAGGACAAAACATACACACTGGTTGTCTCTTCTTGAAACTGTAATATAAATCTAGGGTCCAGTCATATCACAAGTATCATCTAA
CCAAGCACTTGGGGAAATACAAGTGTATATAAATACAGTCATTGGGAATGAGGAGACATCTGGGATAAATAAGTCTTGTTTTAAGTACATGGTTTAACACAACCTGCTTCAGGAATCTGATGGGATTC
AAACAGGTATTAGCTAACCATTACTACCAAGGAGGATGATCAGAGTTAGTTAATAGAGGCGTGACTAATCCTTCTCACTTTTCCTCATTGCTCTTTTCATTTAGCGTTGTCTTTACGTATTTCAGGTT
CATCCAACCTCCTGCAGATCACATCAGAAACTAGGAAGTTTAACTAGGGGACATCAAAATCACACCCAAAGAATGGATCAAGTGGCAGTGGCCAGTTCTCCTCCCATGTTGATTTTAAAAGCTTTACC
CTAGAATATGGCATAAATTCTAGAGCAAGTGAATTTTGAAAGACAATGTTCAGGGGCAGGGTCTTTGGAGCACTAAGCTTTTTGCTTTGCTTTGGGAATTTCTTCCCTTTAAAAAACATTCTCGTCTC
TAGACCCTAGAGTACTGCTTGGTTGCTTTGACAAACATTGGCATCTTAGTCCTTTCATCACGATCTTAAACTTTCGTGATAGGGTGAGGATTTCAGGTGGTCAAACACGCTTCATCCTCACGGAGTCA
TGCAAGGTGAACAGAAATACCTGACTCACCTACTAAGGGCTGAGTGTTTGCCTAATGCCCTTTCAGAGGCAAAGGCCCTGTTTCTTCCCTCACAGCCCCCTTTCCAAATTGATGAGGATCTCTGGCCC
CTAGTCATGCTGGTCATGAAGGTTGATTTCACACCAGTAAAATAAATCAGTGTAGCCCAAAGGGGTTATGAAGGGAGAGTTAGAGCAAACAGTTGTTGAGCAGCTGTTTGCTTAAGCAGCCTCAGAAC
CTGTAGATGTGCTGCTGCAACCTGCTTAACACGGAGGTTCCGTGTCCAGCAGGCTTCTGAATCTGTTAAGCCTGAATCAGAATACCTTCCATGTGAAGAAAGGCATGTCCATTCTCTCCTCAGCTTTA
TCCACATGAAATGTAGTGTTCAGTTGCCATGTGCCCAGATAGCTACAAGGTAGAAGCCTGGCTTCCTGCCTCATCGTACAGAAGAAATGCCAAGACTAGCCAGTGACCCCTTTGCTTTTAATTGTGTA
GAACATGCTGTTGCACCCCCTTTTGCTGTAGATTAAATCTTTTCTAGGGAGGAAACCAAAGGAGCTAGCTCGAGAACCTAATGGAAATGTTTACTCCAATCTCTGCTGAGTCTGGAGGTATCACATTC
CCAGTCATCCTCGGGACTGGCCTGGTGGGGGCGCTGTGGGCAAAGTCTTGTTTACTACATAATGCACATGATAAATGGCCTTATAAACTGATTCTTTGTGGTATGATGACTTATAATAAACTGACCCT
AAAGAA

hide sequence


Protein RefSeqs	XP_020955213	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000045377
	ENSSSCP00000045377.1
	ENSSSCP00015018742.1
	ENSSSCP00025039556.1
	ENSSSCP00030019926.1
	ENSSSCP00035014715.1
	ENSSSCP00040010261.1
	ENSSSCP00045041548.1
	ENSSSCP00050029130.1
	ENSSSCP00060001246.1
	ENSSSCP00065044907.1
	ENSSSCP00070009893.1

RefSeq Acc Id:

XP_020955213 ⟸ XM_021099554

- UniProtKB:

A0A4X1T2C0 (UniProtKB/TrEMBL), F1SE08 (UniProtKB/TrEMBL), A0A8D0NHS0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MMRSGPEGCCRRPVRANGCVANGEVRNGYVRSSAAAAAAAAGQIHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQQDFVSLYQDFENFYTRNLYMR
IRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKDVINMGSYNYLGFARNTGACQEAAAKVLEEYGVGVCSTRQEIGNLDKHEELEKLVASFLGVEAAMAYGMGFATNSMNIPALVSKGCLIL
SDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVDYFGLDPEDVDIMMGTFTKSFGASG
GYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTTLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNVGVVVVGFPATPIIESRARFCLS
AAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED

hide sequence

Ensembl Acc Id:

ENSSSCP00000045377 ⟸ ENSSSCT00000064054

Protein Domains

Aminotransferase class I/classII large

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000002404	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015035547	UniProtKB/TrEMBL
	ENSSSCG00025065785	UniProtKB/TrEMBL
	ENSSSCG00030031970	UniProtKB/TrEMBL
	ENSSSCG00035027897	UniProtKB/TrEMBL
	ENSSSCG00040017885	UniProtKB/TrEMBL
	ENSSSCG00045034596	UniProtKB/TrEMBL
	ENSSSCG00050049928	UniProtKB/TrEMBL
	ENSSSCG00060003063	UniProtKB/TrEMBL
	ENSSSCG00065073986	UniProtKB/TrEMBL
	ENSSSCG00070006284	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000064054	ENTREZGENE
	ENSSSCT00000064054.3	UniProtKB/TrEMBL
	ENSSSCT00015047364.1	UniProtKB/TrEMBL
	ENSSSCT00025090290.1	UniProtKB/TrEMBL
	ENSSSCT00030044230.1	UniProtKB/TrEMBL
	ENSSSCT00035036910.1	UniProtKB/TrEMBL
	ENSSSCT00040024176.1	UniProtKB/TrEMBL
	ENSSSCT00045059294.1	UniProtKB/TrEMBL
	ENSSSCT00050067922.1	UniProtKB/TrEMBL
	ENSSSCT00060003779.1	UniProtKB/TrEMBL
	ENSSSCT00065101887.1	UniProtKB/TrEMBL
	ENSSSCT00070012007.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.640.10	UniProtKB/TrEMBL
	3.90.1150.10	UniProtKB/TrEMBL
InterPro	Aminotrans_II_pyridoxalP_BS	UniProtKB/TrEMBL
	Aminotransferase_I/II	UniProtKB/TrEMBL
	AON_synthase_class-II	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_dom1	UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_major	UniProtKB/TrEMBL
NCBI Gene	SPTLC2	ENTREZGENE
PANTHER	CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE	UniProtKB/TrEMBL
	SERINE PALMITOYLTRANSFERASE 2	UniProtKB/TrEMBL
Pfam	Aminotran_1_2	UniProtKB/TrEMBL
PROSITE	AA_TRANSFER_CLASS_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53383	UniProtKB/TrEMBL
UniProt	A0A4X1T2C0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0NHS0	ENTREZGENE, UniProtKB/TrEMBL
	F1SE08	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:93440	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB