LOC100739508 (glutathione S-transferase P-like) - Rat Genome Database

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Gene: LOC100739508 (glutathione S-transferase P-like) Sus scrofa
Analyze
Symbol: LOC100739508
Name: glutathione S-transferase P-like
RGD ID: 14068854
Description: ENCODES a protein that exhibits dinitrosyl-iron complex binding (ortholog); fatty acid binding (ortholog); glutathione peroxidase activity (ortholog); INVOLVED IN glutathione derivative biosynthetic process (ortholog); hepoxilin biosynthetic process (ortholog); linoleic acid metabolic process (ortholog); PARTICIPATES IN paracetamol pharmacokinetics pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); TRAF2-GSTP1 complex (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; glutathione; monobromobimane
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.125,005,498 - 5,009,247 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,634,793 - 3,637,656 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
LOC100739508Pigacute kidney failure  ISOGSTP1 (Homo sapiens)9068941 RGDPMID:20798258 and REF_RGD_ID:6903954
LOC100739508Pigacute lymphoblastic leukemia no_associationISOGSTP1 (Homo sapiens)9068941DNA:polymorphism: :1578 a>G(human)RGDPMID:23979883 and REF_RGD_ID:10755417
LOC100739508Pigacute lymphoblastic leukemia disease_progressionISOGSTP1 (Homo sapiens)9068941DNA:haplotype:cds:RGDPMID:10666194 and REF_RGD_ID:10450829
LOC100739508Pigacute lymphoblastic leukemia susceptibilityISOGSTP1 (Homo sapiens)9068941DNA:transition mutation:exon:RGDPMID:15738600 and REF_RGD_ID:10755321
LOC100739508Pigacute myeloid leukemia susceptibilityISOGSTP1 (Homo sapiens)9068941chemotherapy-inducedRGDPMID:11553769 and REF_RGD_ID:10755420
LOC100739508Pigacute myeloid leukemia susceptibilityISOGSTP1 (Homo sapiens)9068941 RGDPMID:11906705 and REF_RGD_ID:10755328
LOC100739508Pigacute myeloid leukemia susceptibilityISOGSTP1 (Homo sapiens)9068941DNA:polymorphism:cds:p.I105V(human)RGDPMID:21729529 and REF_RGD_ID:10755422
LOC100739508PigAirway Obstruction severityISOGSTP1 (Homo sapiens)9068941associated with Bronchial Hyperreactivity and DNA:polymorphism:exon:p.I105V (rs1695) (human)RGDPMID:10919500 and REF_RGD_ID:4142525
LOC100739508Pigalcohol use disorder  ISOGSTP1 (Homo sapiens)9068941DNA:SNP:: rs1695(human)RGDPMID:31886888 and REF_RGD_ID:597621684
LOC100739508Pigallergic disease susceptibilityISOGSTP1 (Homo sapiens)9068941DNA:polymorphism:exon:p.I105V (rs1695) (human)RGDPMID:20526719 and REF_RGD_ID:5133266
LOC100739508PigAlzheimer's disease susceptibilityISOGSTP1 (Homo sapiens)9068941 RGDPMID:15805147 and REF_RGD_ID:5490123
LOC100739508PigAlzheimer's disease onsetISOGSTP1 (Homo sapiens)9068941DNA:polymorphism:exon:RGDPMID:17911365 and REF_RGD_ID:5490271
LOC100739508PigAlzheimer's disease  ISOGSTP1 (Homo sapiens)9068941DNA:polymorphismsRGDPMID:24584466 and REF_RGD_ID:10401912
LOC100739508Pigasthma  ISOGSTP1 (Homo sapiens)9068941DNA:SNP: :p.A114V (human)RGDPMID:18709160 and REF_RGD_ID:4140947
LOC100739508Pigasthma no_associationISOGSTP1 (Homo sapiens)9068941DNA:SNPs: :p.I105V and p.A114V (human)RGDPMID:16176403 and REF_RGD_ID:4142519
LOC100739508Pigasthma severityISOGSTP1 (Homo sapiens)9068941DNA:polymorphism:exon:p.I105V (rs1695) (human)RGDPMID:10806136 and REF_RGD_ID:4142526
LOC100739508Pigasthma  ISOGSTP1 (Homo sapiens)9068941DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)RGDPMID:15693909 and REF_RGD_ID:5490999
LOC100739508Pigasthma susceptibilityISOGSTP1 (Homo sapiens)9068941DNA:SNPs:intron and exon:(rs749174), (rs1138272)(human)RGDPMID:20210814 and REF_RGD_ID:5490991
LOC100739508Pigasthma disease_progressionISOGSTP1 (Homo sapiens)9068941DNA:polymorphism:exon:p.I105V (human)RGDPMID:18057098 and REF_RGD_ID:4140951
LOC100739508Pigasthma  ISOGSTP1 (Homo sapiens)9068941DNA:SNPs: :p.I105V and p.A114V (human)RGDPMID:20858151 and REF_RGD_ID:5490985
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Original Reference(s)
LOC100739508PigAicardi-Goutieres Syndrome 3  ISOGSTP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Aicardi-Goutieres syndrome 3ClinVarPMID:28492532
LOC100739508Pigchronic obstructive pulmonary disease  ISOGSTP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary disease more ...ClinVarPMID:25741868
LOC100739508Pigimmune system disease  ISOGSTP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Abnormality of immune system physiologyClinVarPMID:25741868
LOC100739508Pigimmunodeficiency 90  ISOGSTP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Infections more ...ClinVarPMID:28492532
LOC100739508Pigintellectual disability  ISOGSTP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
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Original Reference(s)
LOC100739508PigAcute Coronary Syndrome  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21751358
LOC100739508Pigacute kidney failure  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20623750
LOC100739508Pigamphetamine abuse  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15729709
LOC100739508Pigamyotrophic lateral sclerosis  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16109392
LOC100739508Pigasthma  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:11994713 more ...
LOC100739508Pigautism spectrum disorder  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:35663546
LOC100739508Pigautistic disorder  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17404132
LOC100739508PigBreast Neoplasms  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25322848
LOC100739508Pigcarcinoma  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:11196146
LOC100739508Pigcarotid artery disease  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16973168
LOC100739508PigChemical and Drug Induced Liver Injury  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20623750 and PMID:25226513
LOC100739508PigChromosome Aberrations  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16537716
LOC100739508Pigchronic myeloid leukemia  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20843134
LOC100739508Pigcontact dermatitis  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25724174
LOC100739508PigDisease Progression  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21364753
LOC100739508Pigdrug allergy  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20485159
LOC100739508Pigessential tremor  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:18215156
LOC100739508PigExperimental Liver Neoplasms  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20188851 more ...
LOC100739508Pighepatocellular carcinoma  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:9029167
LOC100739508Pighigh grade glioma  ISOGSTP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16899598
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Original Reference(s)
LOC100739508Pig1-chloro-2,4-dinitrobenzene affects metabolic processingEXP 6480464GSTP1 protein affects the metabolism of DinitrochlorobenzeneCTDPMID:14573868
LOC100739508Pigglutathione multiple interactionsEXP 6480464GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione]CTDPMID:14573868
LOC100739508Pigmonobromobimane multiple interactionsEXP 6480464GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione]CTDPMID:14573868
LOC100739508Pigmonobromobimane decreases activityEXP 6480464monobromobimane results in decreased activity of GSTP1 proteinCTDPMID:14573868


Biological Process
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Original Reference(s)
LOC100739508Pigglutathione derivative biosynthetic process involved_inISOGSTP1 (Homo sapiens)9068941 PMID:9084911UniProtPMID:9084911
LOC100739508Pigglutathione metabolic process involved_inIBAFB:FBgn0010226 more ...150520179 GO_CentralGO_REF:0000033
LOC100739508Pighepoxilin biosynthetic process involved_inISOGSTP1 (Homo sapiens)9068941 PMID:21046276UniProtPMID:21046276
LOC100739508Piglinoleic acid metabolic process involved_inISOGSTP1 (Homo sapiens)9068941 PMID:16624487BHF-UCLPMID:16624487
LOC100739508Pignegative regulation of ERK1 and ERK2 cascade involved_inISOGSTP1 (Homo sapiens)9068941 PMID:11408560BHF-UCLPMID:11408560
LOC100739508Pignegative regulation of extrinsic apoptotic signaling pathway involved_inISOGSTP1 (Homo sapiens)9068941 PMID:16636664BHF-UCLPMID:16636664
LOC100739508Pignegative regulation of interleukin-1 beta production involved_inISOGSTP1 (Homo sapiens)9068941 PMID:18962899BHF-UCLPMID:18962899
LOC100739508Pignegative regulation of JNK cascade involved_inISOGSTP1 (Homo sapiens)9068941 PMID:16636664BHF-UCLPMID:16636664
LOC100739508Pignegative regulation of monocyte chemotactic protein-1 production involved_inISOGSTP1 (Homo sapiens)9068941 PMID:18962899BHF-UCLPMID:18962899
LOC100739508Pignegative regulation of tumor necrosis factor production involved_inISOGSTP1 (Homo sapiens)9068941 PMID:18962899BHF-UCLPMID:18962899
LOC100739508Pigprostaglandin metabolic process involved_inISOGSTP1 (Homo sapiens)9068941 PMID:9084911UniProtPMID:9084911
LOC100739508Pigxenobiotic metabolic process involved_inISOGSTP1 (Homo sapiens)9068941 PMID:1540159UniProtPMID:1540159
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Cellular Component

  
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Original Reference(s)
LOC100739508Pigcytosol located_inISOGSTP1 (Homo sapiens)9068941 HPAGO_REF:0000052
LOC100739508Pigcytosol is_active_inIBAMGI:95864 more ...150520179 GO_CentralGO_REF:0000033
LOC100739508Pigmitochondrion located_inISOGSTP1 (Homo sapiens)9068941 HPAGO_REF:0000052
LOC100739508PigTRAF2-GSTP1 complex part_ofISOGSTP1 (Homo sapiens)9068941 PMID:16636664BHF-UCLPMID:16636664

Molecular Function
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Imported Annotations - SMPDB

Object Symbol
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Original Reference(s)
LOC100739508Pigparacetamol pharmacokinetics pathway   ISOGSTP1 (Homo sapiens)9068941 SMPDBSMP:00640
PMID:22301074   PMID:30032202  



LOC100739508
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.125,005,498 - 5,009,247 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,634,793 - 3,637,656 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GSTP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,583,812 - 67,586,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,583,742 - 67,586,656 (+)EnsemblGRCh38hg38GRCh38
GRCh371167,351,283 - 67,354,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,107,862 - 67,110,699 (+)NCBINCBI36Build 36hg18NCBI36
Build 341167,107,861 - 67,110,699NCBI
Celera1164,685,527 - 64,688,585 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1163,680,236 - 63,683,230 (+)NCBIHuRef
CHM1_11167,234,118 - 67,237,177 (+)NCBICHM1_1
T2T-CHM13v2.01167,578,501 - 67,581,343 (+)NCBIT2T-CHM13v2.0

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Variants in LOC100739508
88 total Variants





RefSeq Transcripts XM_005660621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01082166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_005660621   ⟹   XP_005660678
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.125,005,498 - 5,009,247 (-)NCBI
Sequence:
Protein RefSeqs XP_005660678 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000013714
  ENSSSCP00000013714.4
  ENSSSCP00000045999.3
  ENSSSCP00070008511.1
RefSeq Acc Id: XP_005660678   ⟸   XM_005660621
- UniProtKB: A0A4X1T0S7 (UniProtKB/TrEMBL)
- Sequence:
GST C-terminal   GST N-terminal



1 to 29 of 29 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000060071 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070005457 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014100 ENTREZGENE
  ENSSSCT00000014100.5 UniProtKB/TrEMBL
  ENSSSCT00000062862.3 UniProtKB/TrEMBL
  ENSSSCT00070010369.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.10 UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro Glutathione-S-Trfase_C-like UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/TrEMBL
  GST_C UniProtKB/TrEMBL
  GST_pi UniProtKB/TrEMBL
  GST_superfamily UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene LOC100739508 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  GST CLASS-PI UniProtKB/TrEMBL
Pfam GST_C_3 UniProtKB/TrEMBL
  GST_N UniProtKB/TrEMBL
PRINTS GSTRNSFRASEP UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/TrEMBL
  GST_NTER UniProtKB/TrEMBL
Superfamily-SCOP GST C-terminal domain-like UniProtKB/TrEMBL
  Thioredoxin-like UniProtKB/TrEMBL
UniProt A0A287AQ27_PIG UniProtKB/TrEMBL
  A0A4X1T0S7 ENTREZGENE, UniProtKB/TrEMBL
  F1RVN0_PIG UniProtKB/TrEMBL
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