GPSM2 (G protein signaling modulator 2) - Rat Genome Database

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Gene: GPSM2 (G protein signaling modulator 2) Sus scrofa
Analyze
Symbol: GPSM2
Name: G protein signaling modulator 2
RGD ID: 13979079
Description: ENCODES a protein that exhibits dynein complex binding (inferred); G-protein alpha-subunit binding (inferred); GDP-dissociation inhibitor activity (inferred); INVOLVED IN establishment of mitotic spindle orientation (ortholog); lung epithelial cell differentiation (ortholog); neurotransmitter receptor localization to postsynaptic specialization membrane (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive nonsyndromic deafness (ortholog); Chudley-Mccullough syndrome (ortholog); FOUND IN apical part of cell (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G-protein-signaling modulator 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4111,102,396 - 111,165,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14111,100,912 - 111,165,902 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,594,274 - 121,661,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
GPSM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4111,102,396 - 111,165,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14111,100,912 - 111,165,902 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,594,274 - 121,661,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPSM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381108,876,985 - 108,934,545 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1108,875,350 - 108,934,545 (+)EnsemblGRCh38hg38GRCh38
GRCh371109,419,607 - 109,477,167 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361109,221,350 - 109,274,546 (+)NCBINCBI36Build 36hg18NCBI36
Build 341109,131,868 - 109,185,060NCBI
Celera1107,689,180 - 107,742,602 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1107,312,482 - 107,365,905 (+)NCBIHuRef
CHM1_11109,534,554 - 109,587,989 (+)NCBICHM1_1
T2T-CHM13v2.01108,910,322 - 108,967,901 (+)NCBIT2T-CHM13v2.0
Gpsm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,585,954 - 108,629,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,585,954 - 108,629,625 (-)EnsemblGRCm39 Ensembl
GRCm383108,678,270 - 108,722,331 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,678,638 - 108,722,309 (-)EnsemblGRCm38mm10GRCm38
MGSCv373108,481,556 - 108,525,217 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,806,694 - 108,850,199 (-)NCBIMGSCv36mm8
Celera3111,013,385 - 111,057,040 (-)NCBICelera
Cytogenetic Map3F3NCBI
cM Map347.53NCBI
Gpsm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82199,015,250 - 199,063,788 (-)NCBIGRCr8
mRatBN7.22196,327,149 - 196,375,322 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,327,149 - 196,375,154 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,965,006 - 204,004,696 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,846,975 - 201,886,687 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,663,951 - 196,703,663 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02211,480,120 - 211,528,096 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,480,400 - 211,527,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,953,071 - 230,992,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,278,765 - 204,319,522 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2188,970,456 - 189,014,462 (-)NCBICelera
Cytogenetic Map2q34NCBI
Gpsm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,334,462 - 12,387,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,334,462 - 12,387,262 (+)NCBIChiLan1.0ChiLan1.0
GPSM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,371,171 - 118,428,126 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,531,227 - 117,588,204 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,253,158 - 111,309,619 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,418,940 - 110,474,066 (+)NCBIpanpan1.1PanPan1.1panPan2
GPSM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,828,611 - 42,878,334 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl642,824,455 - 42,868,690 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha645,603,445 - 45,654,570 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0643,160,694 - 43,211,820 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl643,149,595 - 43,212,031 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1642,891,237 - 42,942,313 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0642,850,140 - 42,900,772 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0643,291,232 - 43,342,358 (-)NCBIUU_Cfam_GSD_1.0
Gpsm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,597,321 - 19,667,028 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936704462,971 - 516,829 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936704462,984 - 516,929 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPSM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12024,659,470 - 24,713,714 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2024,659,957 - 24,713,677 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603833,636,699 - 33,692,971 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpsm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247724,651,326 - 4,704,280 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247724,634,005 - 4,704,280 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPSM2
2799 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 12 1
Low 5 4 3 5 2 11 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000023502   ⟹   ENSSSCP00000021274
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4111,102,396 - 111,165,886 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091839   ⟹   ENSSSCP00000080133
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4111,103,190 - 111,165,886 (-)Ensembl
RefSeq Acc Id: XM_021090096   ⟹   XP_020945755
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14111,100,912 - 111,165,902 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021090097   ⟹   XP_020945756
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14111,100,912 - 111,165,889 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021090098   ⟹   XP_020945757
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14111,102,396 - 111,165,890 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021090099   ⟹   XP_020945758
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14111,102,396 - 111,165,890 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002343535
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14111,115,034 - 111,165,890 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020945755   ⟸   XM_021090096
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TE08 (UniProtKB/TrEMBL),   I3LB55 (UniProtKB/TrEMBL),   A0A480UHZ0 (UniProtKB/TrEMBL),   A0A8D0LEM7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945756   ⟸   XM_021090097
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TI86 (UniProtKB/TrEMBL),   A0A8D1L3V9 (UniProtKB/TrEMBL),   A0A8D0I6V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945758   ⟸   XM_021090099
- Peptide Label: isoform X4
- UniProtKB: A0A8D1L3V9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945757   ⟸   XM_021090098
- Peptide Label: isoform X3
- UniProtKB: A0A480UHZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000021274   ⟸   ENSSSCT00000023502
RefSeq Acc Id: ENSSSCP00000080133   ⟸   ENSSSCT00000091839


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021440 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005004876 UniProtKB/TrEMBL
  ENSSSCG00025012336 UniProtKB/TrEMBL
  ENSSSCG00035004749 UniProtKB/TrEMBL
  ENSSSCG00045028657 UniProtKB/TrEMBL
  ENSSSCG00050038884 UniProtKB/TrEMBL
  ENSSSCG00065071116 UniProtKB/TrEMBL
  ENSSSCG00070009076 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000023502 ENTREZGENE
  ENSSSCT00000023502.3 UniProtKB/TrEMBL
  ENSSSCT00000091839 ENTREZGENE
  ENSSSCT00000091839.1 UniProtKB/TrEMBL
  ENSSSCT00005007325.1 UniProtKB/TrEMBL
  ENSSSCT00005007363.1 UniProtKB/TrEMBL
  ENSSSCT00025016300.1 UniProtKB/TrEMBL
  ENSSSCT00035005972.1 UniProtKB/TrEMBL
  ENSSSCT00045049212.1 UniProtKB/TrEMBL
  ENSSSCT00050052432.1 UniProtKB/TrEMBL
  ENSSSCT00065097729.1 UniProtKB/TrEMBL
  ENSSSCT00070017620.1 UniProtKB/TrEMBL
  ENSSSCT00070017624.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro GoLoco_motif UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene GPSM2 ENTREZGENE
PANTHER G-PROTEIN-SIGNALING MODULATOR 2 UniProtKB/TrEMBL
  LD33695P UniProtKB/TrEMBL
Pfam GoLoco UniProtKB/TrEMBL
  TPR_10 UniProtKB/TrEMBL
  TPR_12 UniProtKB/TrEMBL
  TPR_7 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PROSITE GOLOCO UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
SMART GoLoco UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A480UHZ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TE08 ENTREZGENE
  A0A4X1TI86 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0I6V6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LEM7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1L3V9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FMK8_PIG UniProtKB/TrEMBL
  I3LB55 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1TE08 UniProtKB/TrEMBL
VGNC ID VGNC:88649 ENTREZGENE