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Gene: Gpsm2 (G-protein signalling modulator 2 (AGS3-like, C. elegans)) Mus musculus
Symbol: Gpsm2
Name: G-protein signalling modulator 2 (AGS3-like, C. elegans)
Description: Exhibits G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Involved in establishment of mitotic spindle orientation and lung epithelial cell differentiation. Localizes to the apical part of cell and lateral cell cortex. Predicted to colocalize with the cell cortex and mitotic spindle pole. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Is expressed in several structures, including ear; eye; genitourinary system; lung; and nervous system. Orthologous to human GPSM2 (G protein signaling modulator 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6230410J09Rik; G-protein-signaling modulator 2; LGN; Pins; pins homolog (Drosophia)
Homo sapiens (human) : GPSM2 (G protein signaling modulator 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gpsm2 (G-protein signaling modulator 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpsm2 (G protein signaling modulator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GPSM2 (G protein signaling modulator 2)
Canis lupus familiaris (dog) : GPSM2 (G protein signaling modulator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpsm2 (G protein signaling modulator 2)
Sus scrofa (pig) : GPSM2 (G protein signaling modulator 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383108,678,270 - 108,722,331 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373108,481,556 - 108,525,217 (-)NCBIGRCm37mm9NCBIm37
MGSCv363108,806,694 - 108,850,199 (-)NCBImm8
Celera3111,013,385 - 111,057,040 (-)NCBICelera
Cytogenetic Map3 F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gpsm2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1556993
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.