FLRT3 (fibronectin leucine rich transmembrane protein 3) - Rat Genome Database

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Gene: FLRT3 (fibronectin leucine rich transmembrane protein 3) Sus scrofa
Analyze
Symbol: FLRT3
Name: fibronectin leucine rich transmembrane protein 3
RGD ID: 13977947
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); High Myopia (ortholog); FOUND IN axon terminus (ortholog); glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat transmembrane protein FLRT3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,940,492 - 22,954,424 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11722,940,491 - 22,955,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,670,538 - 25,684,556 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FLRT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,940,492 - 22,954,424 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11722,940,491 - 22,955,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,670,538 - 25,684,556 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLRT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382014,322,985 - 14,337,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2014,322,985 - 14,337,614 (-)EnsemblGRCh38hg38GRCh38
GRCh372014,303,631 - 14,318,258 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362014,252,643 - 14,266,270 (-)NCBINCBI36Build 36hg18NCBI36
Build 342014,252,642 - 14,266,270NCBI
Celera2014,379,950 - 14,393,623 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2014,264,895 - 14,278,567 (-)NCBIHuRef
CHM1_12014,304,603 - 14,318,275 (-)NCBICHM1_1
T2T-CHM13v2.02014,372,130 - 14,386,755 (-)NCBIT2T-CHM13v2.0
Flrt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,500,118 - 140,513,396 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,492,834 - 140,513,389 (-)EnsemblGRCm39 Ensembl
GRCm382140,658,198 - 140,671,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,650,914 - 140,671,469 (-)EnsemblGRCm38mm10GRCm38
MGSCv372140,483,934 - 140,497,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362140,349,640 - 140,362,910 (-)NCBIMGSCv36mm8
Celera2141,850,226 - 141,863,510 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Flrt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,448,115 - 148,461,458 (-)NCBIGRCr8
mRatBN7.23127,994,491 - 128,008,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,994,226 - 128,007,841 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,850,711 - 131,863,013 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,434,799 - 140,447,106 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03138,137,914 - 138,150,220 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,684,446 - 134,696,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,683,065 - 134,696,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03141,134,890 - 141,147,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,922,726 - 128,934,866 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3126,621,420 - 126,633,560 (-)NCBICelera
Cytogenetic Map3q41NCBI
Flrt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,669,749 - 23,683,235 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541523,669,749 - 23,683,235 (-)NCBIChiLan1.0ChiLan1.0
FLRT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22115,223,313 - 15,238,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12015,217,075 - 15,235,719 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02014,294,903 - 14,310,584 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12014,279,967 - 14,293,632 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2014,281,522 - 14,283,471 (-)Ensemblpanpan1.1panPan2
FLRT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,354,151 - 8,367,601 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,364,115 - 8,366,064 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,165,848 - 8,179,356 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0248,763,355 - 8,776,862 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl248,763,393 - 8,776,857 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,356,554 - 8,370,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,455,701 - 8,469,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0248,810,713 - 8,824,225 (+)NCBIUU_Cfam_GSD_1.0
Flrt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,532,853 - 5,546,392 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,532,554 - 5,547,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLRT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1243,252,181 - 43,267,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl243,255,347 - 43,257,296 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660543,530,057 - 3,543,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flrt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474115,343,653 - 15,355,727 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474115,343,304 - 15,355,742 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FLRT3
189 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000007750   ⟹   ENSSSCP00000007541
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1722,940,492 - 22,954,424 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000035207   ⟹   ENSSSCP00000030135
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1722,940,500 - 22,954,366 (-)Ensembl
RefSeq Acc Id: XM_001926449   ⟹   XP_001926484
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11722,940,491 - 22,955,277 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005672710   ⟹   XP_005672767
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11722,940,491 - 22,955,276 (-)NCBI
Sequence:
RefSeq Acc Id: XP_001926484   ⟸   XM_001926449
- UniProtKB: A0A8D1V7H9 (UniProtKB/TrEMBL),   K7GQG6 (UniProtKB/TrEMBL),   F1SBJ0 (UniProtKB/TrEMBL),   A0A481BIJ7 (UniProtKB/TrEMBL),   A0A4X1UT49 (UniProtKB/TrEMBL),   A0A8D0HSE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672767   ⟸   XM_005672710
- UniProtKB: A0A8D1V7H9 (UniProtKB/TrEMBL),   K7GQG6 (UniProtKB/TrEMBL),   F1SBJ0 (UniProtKB/TrEMBL),   A0A481BIJ7 (UniProtKB/TrEMBL),   A0A4X1UT49 (UniProtKB/TrEMBL),   A0A8D0HSE3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000030135   ⟸   ENSSSCT00000035207
Ensembl Acc Id: ENSSSCP00000007541   ⟸   ENSSSCT00000007750
Protein Domains
Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007079 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005003517 UniProtKB/TrEMBL
  ENSSSCG00015033283 UniProtKB/TrEMBL
  ENSSSCG00025054191 UniProtKB/TrEMBL
  ENSSSCG00030002563 UniProtKB/TrEMBL
  ENSSSCG00035050575 UniProtKB/TrEMBL
  ENSSSCG00040056014 UniProtKB/TrEMBL
  ENSSSCG00045015027 UniProtKB/TrEMBL
  ENSSSCG00050004691 UniProtKB/TrEMBL
  ENSSSCG00055026186 UniProtKB/TrEMBL
  ENSSSCG00060034807 UniProtKB/TrEMBL
  ENSSSCG00065034821 UniProtKB/TrEMBL
  ENSSSCG00070019999 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007750 ENTREZGENE
  ENSSSCT00000007750.4 UniProtKB/TrEMBL
  ENSSSCT00000035207.2 UniProtKB/TrEMBL
  ENSSSCT00005005130.1 UniProtKB/TrEMBL
  ENSSSCT00005005150.1 UniProtKB/TrEMBL
  ENSSSCT00015044054.1 UniProtKB/TrEMBL
  ENSSSCT00015044096.1 UniProtKB/TrEMBL
  ENSSSCT00025074084.1 UniProtKB/TrEMBL
  ENSSSCT00025074129.1 UniProtKB/TrEMBL
  ENSSSCT00030003266.1 UniProtKB/TrEMBL
  ENSSSCT00030003278.1 UniProtKB/TrEMBL
  ENSSSCT00035067393.1 UniProtKB/TrEMBL
  ENSSSCT00035067397.1 UniProtKB/TrEMBL
  ENSSSCT00040075888.1 UniProtKB/TrEMBL
  ENSSSCT00040075913.1 UniProtKB/TrEMBL
  ENSSSCT00045025486.1 UniProtKB/TrEMBL
  ENSSSCT00045025514.1 UniProtKB/TrEMBL
  ENSSSCT00050006470.1 UniProtKB/TrEMBL
  ENSSSCT00050006474.1 UniProtKB/TrEMBL
  ENSSSCT00055051683.1 UniProtKB/TrEMBL
  ENSSSCT00055051718.1 UniProtKB/TrEMBL
  ENSSSCT00060047179.1 UniProtKB/TrEMBL
  ENSSSCT00060047184.1 UniProtKB/TrEMBL
  ENSSSCT00065047381.1 UniProtKB/TrEMBL
  ENSSSCT00065047382.1 UniProtKB/TrEMBL
  ENSSSCT00070039651.1 UniProtKB/TrEMBL
  ENSSSCT00070039658.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SLRP UniProtKB/TrEMBL
KEGG Report ssc:100158214 UniProtKB/TrEMBL
NCBI Gene FLRT3 ENTREZGENE
PANTHER AGAP007037-PA UniProtKB/TrEMBL
  AGAP008170-PA UniProtKB/TrEMBL
  LEUCINE RICH REPEAT FAMILY PROTEIN UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt A0A481BIJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UT49 ENTREZGENE
  A0A8D0HSE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1V7H9 ENTREZGENE, UniProtKB/TrEMBL
  F1SBJ0 ENTREZGENE, UniProtKB/TrEMBL
  K7GQG6 ENTREZGENE
UniProt Secondary A0A4X1UT49 UniProtKB/TrEMBL
  K7GQG6 UniProtKB/TrEMBL
VGNC ID VGNC:96304 ENTREZGENE