Flrt3 (fibronectin leucine rich transmembrane protein 3) - Rat Genome Database

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Gene: Flrt3 (fibronectin leucine rich transmembrane protein 3) Ictidomys tridecemlineatus
Analyze
Symbol: Flrt3
Name: fibronectin leucine rich transmembrane protein 3
RGD ID: 12580140
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); fibroblast growth factor receptor binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synapse assembly (ortholog); response to axon injury (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); High Myopia (ortholog); FOUND IN axon terminus (ortholog); glutamatergic synapse (ortholog); postsynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibronectin leucine rich transmembrane protein 3, transcript variant X1; fibronectin leucine rich transmembrane protein 3, transcript variant X2; fibronectin leucine rich transmembrane protein 3, transcript variant X3; leucine-rich repeat transmembrane protein FLRT3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,532,853 - 5,546,392 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,532,554 - 5,547,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Flrt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,532,853 - 5,546,392 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,532,554 - 5,547,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLRT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382014,322,985 - 14,337,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2014,322,985 - 14,337,614 (-)EnsemblGRCh38hg38GRCh38
GRCh372014,303,631 - 14,318,258 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362014,252,643 - 14,266,270 (-)NCBINCBI36Build 36hg18NCBI36
Build 342014,252,642 - 14,266,270NCBI
Celera2014,379,950 - 14,393,623 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2014,264,895 - 14,278,567 (-)NCBIHuRef
CHM1_12014,304,603 - 14,318,275 (-)NCBICHM1_1
T2T-CHM13v2.02014,372,130 - 14,386,755 (-)NCBIT2T-CHM13v2.0
Flrt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,500,118 - 140,513,396 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,492,834 - 140,513,389 (-)EnsemblGRCm39 Ensembl
GRCm382140,658,198 - 140,671,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,650,914 - 140,671,469 (-)EnsemblGRCm38mm10GRCm38
MGSCv372140,483,934 - 140,497,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362140,349,640 - 140,362,910 (-)NCBIMGSCv36mm8
Celera2141,850,226 - 141,863,510 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Flrt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,448,115 - 148,461,458 (-)NCBIGRCr8
mRatBN7.23127,994,491 - 128,008,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,994,226 - 128,007,841 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,850,711 - 131,863,013 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,434,799 - 140,447,106 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03138,137,914 - 138,150,220 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,684,446 - 134,696,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,683,065 - 134,696,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03141,134,890 - 141,147,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,922,726 - 128,934,866 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3126,621,420 - 126,633,560 (-)NCBICelera
Cytogenetic Map3q41NCBI
Flrt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,669,749 - 23,683,235 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541523,669,749 - 23,683,235 (-)NCBIChiLan1.0ChiLan1.0
FLRT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22115,223,313 - 15,238,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12015,217,075 - 15,235,719 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02014,294,903 - 14,310,584 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12014,279,967 - 14,293,632 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2014,281,522 - 14,283,471 (-)Ensemblpanpan1.1panPan2
FLRT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,354,151 - 8,367,601 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,364,115 - 8,366,064 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,165,848 - 8,179,356 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0248,763,355 - 8,776,862 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl248,763,393 - 8,776,857 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,356,554 - 8,370,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,455,701 - 8,469,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0248,810,713 - 8,824,225 (+)NCBIUU_Cfam_GSD_1.0
FLRT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,940,492 - 22,954,424 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11722,940,491 - 22,955,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,670,538 - 25,684,556 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLRT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1243,252,181 - 43,267,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl243,255,347 - 43,257,296 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660543,530,057 - 3,543,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flrt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474115,343,653 - 15,355,727 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474115,343,304 - 15,355,742 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000008999   ⟹   ENSSTOP00000008063
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364855,532,853 - 5,546,392 (+)Ensembl
RefSeq Acc Id: XM_005320461   ⟹   XP_005320518
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBI
SpeTri2.0NW_0049364855,532,554 - 5,546,387 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005320462   ⟹   XP_005320519
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBI
SpeTri2.0NW_0049364855,532,963 - 5,547,430 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723255   ⟹   XP_021578930
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640157,101,485 - 157,115,032 (+)NCBI
SpeTri2.0NW_0049364855,532,554 - 5,546,387 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005320518 (Get FASTA)   NCBI Sequence Viewer  
  XP_005320519 (Get FASTA)   NCBI Sequence Viewer  
  XP_021578930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008063.2
GenBank Protein KAG3262818 (Get FASTA)   NCBI Sequence Viewer  
  KAG3262819 (Get FASTA)   NCBI Sequence Viewer  
  KAG3262820 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005320518   ⟸   XM_005320461
- UniProtKB: I3MCQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005320519   ⟸   XM_005320462
- UniProtKB: I3MCQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578930   ⟸   XM_021723255
- UniProtKB: I3MCQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000008063   ⟸   ENSSTOT00000008999
Protein Domains
Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009011 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008999.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SLRP UniProtKB/TrEMBL
NCBI Gene Flrt3 ENTREZGENE
PANTHER AGAP007037-PA UniProtKB/TrEMBL
  AGAP008170-PA UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt I3MCQ8 ENTREZGENE, UniProtKB/TrEMBL