Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | DCDC1 | Human | 4,4'-sulfonyldiphenol | increases methylation | EXP | | 6480464 | bisphenol S results in increased methylation of DCDC1 gene | CTD | PMID:31601247 | DCDC1 | Human | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of DCDC1 gene and Aflatoxin B1 results in decreased methylation of DCDC1 intron | CTD | PMID:27153756 and PMID:30157460 | DCDC1 | Human | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of DCDC1 mRNA | CTD | PMID:32234424 | DCDC1 | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of DCDC1 mRNA | CTD | PMID:33212167 | DCDC1 | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of DCDC1 mRNA | CTD | PMID:32234424 | DCDC1 | Human | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of DCDC1 gene | CTD | PMID:31601247 | DCDC1 | Human | bisphenol A | increases methylation | ISO | Dcdc1-ps1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of DCDC1 gene | CTD | PMID:28505145 | DCDC1 | Human | bisphenol A | decreases expression | ISO | Dcdc1-ps1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DCDC1 mRNA | CTD | PMID:25181051 more ... | DCDC1 | Human | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCDC1 mRNA | CTD | PMID:35301059 | DCDC1 | Human | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of DCDC1 mRNA | CTD | PMID:38568856 | DCDC1 | Human | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCDC1 mRNA | CTD | PMID:35301059 | DCDC1 | Human | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of DCDC1 mRNA | CTD | PMID:27392435 | DCDC1 | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCDC1 mRNA | CTD | PMID:27188386 | DCDC1 | Human | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of DCDC1 mRNA | CTD | PMID:27188386 | DCDC1 | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of DCDC1 mRNA | CTD | PMID:28001369 | DCDC1 | Human | N-Nitrosopyrrolidine | decreases expression | EXP | | 6480464 | N-Nitrosopyrrolidine results in decreased expression of DCDC1 mRNA | CTD | PMID:32234424 | DCDC1 | Human | O-methyleugenol | decreases expression | EXP | | 6480464 | methyleugenol results in decreased expression of DCDC1 mRNA | CTD | PMID:32234424 | DCDC1 | Human | pentanal | decreases expression | EXP | | 6480464 | pentanal results in decreased expression of DCDC1 mRNA | CTD | PMID:26079696 | DCDC1 | Human | rotenone | decreases expression | ISO | Dcdc1-ps1 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of DCDC1 mRNA | CTD | PMID:28374803 | DCDC1 | Human | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | EXP | | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in increased expression of DCDC1 mRNA | CTD | PMID:35811015 | DCDC1 | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCDC1 mRNA | CTD | PMID:27188386 | DCDC1 | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of DCDC1 mRNA | CTD | PMID:34973136 | DCDC1 | Human | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of DCDC1 mRNA | CTD | PMID:29301061 | DCDC1 | Human | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of DCDC1 gene | CTD | PMID:29154799 | DCDC1 | Human | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCDC1 mRNA | CTD | PMID:27188386 | DCDC1 | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of DCDC1 mRNA | CTD | PMID:26272509 and PMID:28001369 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Imported Human Phenotype Annotations - ClinVar
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | GOAs Human GO annotations | GOA_HUMAN data from the GO Consortium |
| 2. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10819331 | PMID:11181995 | PMID:12477932 | PMID:12820024 | PMID:14702039 | PMID:16344560 | PMID:16554811 | PMID:16869982 | PMID:19801982 | PMID:20236041 | PMID:20379614 | PMID:20700443 |
| PMID:21321669 | PMID:21873635 | PMID:22159412 | PMID:22504420 | PMID:22797727 | PMID:26460568 | PMID:30021884 | PMID:31753913 | PMID:33961781 | PMID:37827155 |
Genomics
Comparative Map Data
| DCDC1 (Homo sapiens - human) |
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| Gm9342 (Mus musculus - house mouse) |
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| Dcdc1-ps1 (Rattus norvegicus - Norway rat) |
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| DCDC1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DCDC1 (Canis lupus familiaris - dog) |
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| Dcdc1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| LOC100517025 (Sus scrofa - pig) |
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| DCDC1 (Chlorocebus sabaeus - green monkey) |
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Variants
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Variants in DCDC1
86 total Variants 
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