GWAS736426_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS736426_H (bone density QTL GWAS736426 (human)) Homo sapiens

Symbol: GWAS736426_H
Name: bone density QTL GWAS736426 (human)
RGD ID: 407087450
Trait: bone mineral mass   (VT:0005007)    
Measurement Type: bone mineral density   (CMO:0001226)    
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381130,889,444 - 30,889,445RGD_MAPPER_PIPELINEGRCh38
GRCh371130,910,991 - 30,910,992RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS736426_HHumanbone mineral density  IAGPrs273573405850206Based on the EFO term IDGWAS_CATALOGPMID:29304378

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS736426_HHumanbone mineral mass  IAGPrs273573405850206Based on the EFO term IDGWAS_CATALOGPMID:29304378

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS736426_HHumanbone density  IAGPrs273573405850206 GWAS_CATALOGPMID:29304378
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1351849DCDC1doublecortin domain containing 1113086360331369739Human

Position Markers

Peak: (rs273573)
Human AssemblyChrPosition (strand)Source
GRCh381130,889,444 - 30,889,445RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576345LVC1_HLeft ventricular contractility QTL 1 (human)3.93Left ventricular contractility11797076733970767Human
1559104SCL15_HSerum cholesterol level QTL 15 (human)2.60.06Lipid levelhyperlipidemia susceptibility111589236841892368Human
407087450GWAS736426_Hbone density QTL GWAS736426 (human)2e-08bone mineral mass (VT:0005007)bone mineral density (CMO:0001226)113088944430889445Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS736426_H GCST005348 Total body bone mineral density 56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals A 0.3176 2E-8 7.699 rs273573 0.0342 bone density (EFO:0003923)
 PMID:29304378
Database Acc Id Source(s)
GWAS Catalog GCST005348 GWAS Catalog

RGD Curation Notes
Note Type Note Reference